Researchers at MIT have developed a technique to integrate both analogue and digital computation in living cells, enabling gene circuits capable of carrying out complex processing operations. The synthetic circuits can measure the level of an analogue input and decide whether it's within the right range to turn on an output.
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Researchers found that stimulation from outside world guides neurons' early development, leading to two different types of inhibitory neurons. This adds complexity and regulation to brain circuitry, with implications for treating neurological disorders like autism, schizophrenia, and depression.
Researchers from Tohoku University have developed a technology to stack magnetic tunnel junctions directly on vertical interconnect access, reducing the chip area of STT-MRAM and increasing memory bit yield. This breakthrough will significantly lower manufacturing costs, making STT-MRAM competitive with DRAM.
Scientists have developed a system that can efficiently transfer electrical energy between separated circuits using metamaterials. This breakthrough enables wireless charging of mobile devices at longer distances than current technology.
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University of Illinois researchers have created a simple and scalable graphene patterning technique using stencil masks fabricated via a laser cutter. This approach enables rapid design iterations and pattern replications, promoting cleaner quality graphene patterns without polymeric transfer layers or organic solvents.
A deep-brain structure called the habenula contains two neural circuits that influence whether a fight will be won or lost in zebrafish. The circuits regulate surrender or continuing aggression based on activity levels in different sub-regions, suggesting a dynamic mechanism for determining fight outcomes.
Researchers at Max Planck Florida Institute for Neuroscience used electrophysiological and optical approaches to visualize and manipulate neuronal activity in individual neurons of the somatosensory cortex. They found that the formation of functional microcircuits was determined by specific settings and the number of neurons stimulated...
Researchers will focus on brain-derived neurotrophic factor (BDNF) and its receptor TrkB to develop novel interventions for obesity. The study aims to understand the mechanisms governing energy balance in the body.
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Researchers have developed a terahertz transmitter that can transmit data at over 10 gigabits per second over multiple channels, exceeding 100 gigabits per second. The technology could revolutionize wireless communication with speeds ten times higher than current technology allows.
Researchers at Case Western Reserve University created a complete model to describe serotonin's role in brain development and structure. The study supports the importance of serotonin for normal functioning of neurons, synapses, and networks in the cortex.
A new study reveals GIT proteins as critical presynaptic regulators of synaptic strength, uncovering previously unknown roles in regulating neurotransmitter release. This finding has significant implications for understanding neuronal communication and the development of neurological diseases.
A recent study published in Neuron shows that brain layers facilitate the rapid development of neuronal circuits, but are not essential for establishing cell-type specific connections. The researchers used zebrafish as a model system to demonstrate this and found that layer formation is necessary for speeding up circuit assembly.
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Scientists have discovered that most neurons in visual cortex respond selectively to light vs dark stimuli and combine this information with selectivity for other stimulus features. This discovery sheds new light on how the brain encodes black and white information.
Researchers developed a new method to analyze neural activity, revealing an organized geometric structure in neurons. The study used clique topology and found similar structure in activities among place cells in different experimental conditions.
Scientists have developed an artificial skin that can detect static objects using flexible organic circuits and specialized pressure sensors. The system translates static pressure into digital signals, which are then transferred to the brain cells of mice, offering a potential solution for people with prosthetic limbs to feel sensation
Researchers at MPFI and FIAS will analyze large datasets to understand spontaneous brain activity in early visual cortex development. They aim to extract general principles of how this activity influences cortical development.
Researchers at the University of Georgia found that the same genetic tools responsible for limb development in animals also control the formation of external genitalia in snakes. The study suggests that snakes retained DNA associated with limb development through millions of generations, as it may have been important for their reproduc...
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Researchers at Northwestern University have developed a solution to create stable carbon nanotube-based integrated circuits using newly designed encapsulation layers. These layers protect the sensitive devices from environmental degradation, enabling reliable operation for years or even decades.
Researchers at Virginia Tech Carilion Research Institute used 'brainbow' technique to tag retinal ganglion cell terminals, revealing individual terminals from multiple cells in mature mouse brains. The study challenges traditional understanding of neural development and connections between the retina and brain.
Yevgenia Kozorovitskiy, a Northwestern University scientist, has been named a Rita Allen Foundation Scholar to research how fast-acting antidepressants impact the brain's neural circuitry. Her goal is to improve treatment effectiveness for major depressive disorders.
Physicists at Jena University successfully simulated charged Majorana particles, a theoretical concept long considered impossible. The experiment allows for the study of non-physical processes and may lead to breakthroughs in quantum computing.
Researchers have developed an antireflex device that efficiently uncouples high-frequency signals from nanocomponents to larger circuits. By minimizing impedance differences, the scientists can transmit signals with reduced loss and increase the performance of electronics.
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Scientists have developed a 'Neuronal Positioning System' that maps the axonal wiring of individual neurons, revealing organizational principles of neuronal networks. This new approach enables researchers to study how specific neurons are wired to other types and regions, providing insights into brain function and development.
A breakthrough study published in The Journal of Neuroscience reveals the critical role of a gene associated with a rare disease in pain processing. Lmx1b mutations cause reduced pain responses in patients, but removing this gene only in the spinal cord allows mice to survive, yet results in reduced sensitivity to stimuli.
Researchers found that dietary deficiencies in n-3 polyunsaturated fatty acids limit brain growth during fetal development and early in life. A balanced diet rich in these fatty acids is essential for proper pre- and postnatal neural growth.
Researchers at IRCM have uncovered a new synergy mechanism required for neural circuits to form properly. This breakthrough may lead to the development of tools to repair nerve cells following injuries to the nervous system.
Pediatric dysphagia affects 35-80% of newborns with neurodevelopmental disorders, leading to malnutrition, choking, and infections. The GW researchers will develop fundamental understanding of the disorder through three projects, aiming to define pathology, developmental origins, and prevention strategies.
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Researchers at the Max Planck Florida Institute for Neuroscience will investigate a newly discovered circuit in the visual cortex using novel imaging technologies. The project aims to understand how this circuit processes visual information and interacts with other neural circuits.
The Grete Lundbeck European Brain Research Foundation has awarded TUM Prof. Arthur Konnerth the million-euro Brain Prize for his work on two-photon microscopy, enabling detailed images of individual nerve cells and synapses in living brains. His research has improved understanding of brain development, plasticity, and functional circui...
Quantum physicists at the University of California - Santa Barbara have developed a quantum circuitry system that self-checks for errors and suppresses them, preserving qubits' state(s) and imbuing the system with reliability. The system uses the surface code scheme to detect errors based on parity information.
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Scientists have developed a new mechanism for engineering traits governed by multiple genes, paving the way for personalized gene therapies and regenerative medicine. The approach uses the Cas9 protein to activate specific genes, allowing for precise control over multiple genes and potentially treating diseases.
Researchers at Max Planck Florida Institute for Neuroscience and Frankfurt Institute for Advanced Studies report substantial postnatal changes in the functional properties of brain circuits. These changes improve the ability of brain cells to encode information, enhancing brain function.
Researchers have discovered a neural circuit that controls compulsive sugar consumption in mice without affecting normal feeding behavior, providing a potential target for treating compulsive overeating. The study reveals a distinct subset of neurons responsible for mediating food-seeking behavior and responding to reward consumption.
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Researchers at EPFL have developed a way to control the formation of conductive pathways in ferroelectric materials, allowing for the creation of adaptable electronic circuits. This technology has the potential to miniaturize devices and enable resilient circuits that can function even with damaged components.
Researchers at Berkeley Lab found that proper copper levels modulate spontaneous neural activity in developing circuits, which is critical for brain health and development. The study highlights the importance of managing copper levels to prevent misregulation of signaling in cell-to-cell communications.
Research shows that serotonin's early regulation is vital for brain circuit formation, particularly in inhibitory interneurons. Dysregulation of this system can lead to psychiatric problems, highlighting the importance of understanding its role in brain development.
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A Northwestern University study found that smokers are three times more likely to develop chronic back pain and that quitting the habit may reduce vulnerability to this condition. The research also identified a key brain region involved in addictive behavior and motivated learning.
Researchers have developed a new technique using electromagnetic induction to create a flexibly designed microscopic trap for atoms. This breakthrough could revolutionize the development of quantum technologies, including high-precision sensors and superfast computers.
Scientists have successfully demonstrated the flow of electrical current through long DNA molecules, paving the way for the development of DNA-based programmable circuits. The breakthrough could lead to more sophisticated, cheaper and simpler computer circuits.
Bio-engineers at ETH Zurich have created a biological circuit that controls sensor components using internal timers, enabling precise signal transmission. This breakthrough could lead to reprogramming cancer cells and creating complex bio-computers to detect and kill cancer cells.
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The NIH is developing an advanced electrode array system that will enable researchers to better understand how the brain works through unprecedented resolution and scale. The system, which will pack over 1,000 tiny electrodes, will allow scientists to simultaneously study thousands of neuronal cells in various brain regions during comp...
New Tel Aviv University research reveals a single-neuron 'hub' orchestrates the activity of an entire brain circuit. The study finds that timely activation of cells is fundamental for proper operation of hub neurons, which orchestrate entire network dynamics.
A University of Iowa study found that sleep twitches activate the brains of mammals differently than movements made while awake. Twitches during rapid eye movement (REM) sleep comprise a different class of movement and provide evidence that sleep twitches teach newborns about their limbs.
The NSF/SRC STARSS program aims to reduce the likelihood of unintended behavior in semiconductors. Researchers will focus on strategies and tools for authentication throughout the supply chain and in the field.
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EPFL scientists have developed a silicon-based photonic crystal nanocavity that requires record-low energy to operate as a switch, enabling faster and more efficient technology. The device's high Q factor and small size produce higher light intensity for the same energy, making it a significant step towards optical circuits.
New technologies solve bottlenecks in CLARITY, a technique for peering into the brain, making it easier to understand brain wiring and probe brain diseases. The advancements enable faster data collection and reduce risks associated with imaging valuable clinical samples.
Researchers at USC Viterbi School of Engineering developed a hybrid circuit combining carbon nanotube thin film transistors with indium, gallium and zinc oxide (IGZO) thin film transistors. This energy-efficient hybrid circuit has the potential to replace silicon as the traditional transistor material used in electronic chips.
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Researchers at EPFL create a novel method to design and optimize photonic crystal nanocavities, which can control the flow of light at the nanometer scale. The approach significantly speeds up the development of optical circuits, with quality factors exceeding one million.
Jessell's seminal research revealed how naïve neural cells develop into distinct motor neuron subtypes to form the spinal cord circuitry. His work has helped create a blueprint for treating neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS).
Researchers developed a new circuit board, Neurogrid, capable of simulating 1 million neurons and billions of synaptic connections using 16 custom-designed chips. The device is more efficient than other brain mimics on the power it takes to run a tablet computer.
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Researchers discovered specialized astrocyte functions support specific neurons, contributing to neurodegenerative disorders like ALS. The study also found potential links to developmental disorders such as autism and schizophrenia.
Scientists have successfully directed charges through single molecules using a bi-layer arrangement of organic molecules, enabling precise control over electronic properties. This breakthrough brings us closer to nanoscale circuitry, which could be used in various applications such as OLEDs and biomedical devices.
Researchers at the University of Pennsylvania School of Medicine found a critical link between sleep disruption in early life and adult courtship behavior in fruit flies. The team discovered that sleep deprivation affects dopamine production, leading to impaired development of courtship circuits and altered mating behavior.
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Researchers at MIT have developed a new, low-power signal-processing chip that could lead to a wirelessly rechargeable cochlear implant without external hardware. The device uses the natural microphone of the middle ear and can be charged via an ordinary cell phone in two minutes.
A study published in Cell reveals that obesity in mothers can predispose their children to lifelong obesity and metabolic disorders due to abnormal neuronal circuits in the hypothalamus. Mothers who consume a large amount of fat during the third trimester may be putting their children at risk for these conditions.
A study in mice reveals an essential brain circuit that helps dictate how the eyes connect to the brain, which could lead to new treatments for amblyopia. The research found that manipulating a specific brain circuit can prevent ocular dominance in young mice and induce it in older mice beyond the critical period.
The University of Toronto has awarded Michel Devoret and Robert Schoelkopf the John Stewart Bell Prize for their groundbreaking contributions to quantum mechanics. Their pioneering work in 'circuit quantum electrodynamics' has opened up new avenues for studying fundamental quantum physics.
A new microscopy technique called Through-Focus Scanning Optical Microscopy (TSOM) can detect tiny differences in the three-dimensional shapes of circuit components. This enables the semiconductor industry to improve chips for the next decade or more by measuring features as small as 10 nanometers across.
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A Weill Cornell study reveals that faulty wiring occurs when RNA molecules embedded in a growing axon are not degraded, interfering with new signals meant to guide the axon. This knowledge may lead to new therapies and strategies to correct faulty pathways.
Researchers have identified a protein responsible for controlling the growth of gigantic synapses in the auditory part of the brain. These massive synapses allow for rapid signal transmission, outpacing other neuronal circuits by a fraction of a millisecond, enabling humans to pinpoint sound sources with remarkable accuracy.