Articles tagged with Adipose Tissue
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Researchers at the University of North Carolina discovered that the pelvis continues to widen as people age from 20-79, leading to an estimated three-inch increase in waist size. This finding suggests that pelvic growth contributes to increased body weight and body fat accumulation over time.
A study published in Acta Paediatrica found that physically inactive children as young as 9 years old are at a higher risk of future heart problems. The research showed that moderate to vigorous physical activity accounted for 8% of the variance in cardiac risk scores, while general physical activity accounted for 11% in boys.
Stem cells extracted from human fat may revolutionize soft tissue reconstruction, cartilage and bone development, and cardiovascular disease treatment. The researchers have developed a technique to decellularize adipose tissue, creating a scaffold for stem cell growth.
Researchers at the University of Alabama at Birmingham found that an antioxidant called MitoQ can prevent damage to the liver caused by excessive alcohol consumption. The study suggests that MitoQ may be a useful agent for treating liver damage caused by prolonged, habitual alcohol use.
Researchers identify protein TLE3 as a key regulator of fat cell development, which can be targeted to improve adipose tissue function and alleviate symptoms of diabetes. By understanding how fat cells form, scientists aim to develop better treatments for obesity and related disorders.
Researchers at the University of Edinburgh have identified a protein that plays a key role in storing fat in the body. The study found that mice with high levels of this protein were more prone to developing unhealthy fat tissue after a high-fat diet, highlighting its potential as a target for obesity treatment.
Women with polycystic ovary syndrome (PCOS) have aberrations in their fat tissue that can lead to insulin resistance and increase the risk of developing type 2 diabetes. The study, published in The Journal of Clinical Endocrinology and Metabolism, found that large fat cells and low levels of adiponectin are strongly associated with ins...
Researchers have isolated and characterized adult fat cell-derived stem cells, which maintain their stem cell characteristics and could aid in tissue regeneration. The study's findings suggest that these cells may be useful for cell-based therapies and represent a promising area of research for plastic surgery applications.
A study found that body fat distribution is associated with an increased risk of ER-negative breast cancer. Abdominal adiposity was more strongly linked to ER-negative breast cancer than ER-positive breast cancer, suggesting sex hormone-independent pathways may be involved.
A recent study followed 44 ultra-marathon runners for two months to investigate the physical effects of long-distance running. The research found that runners experienced significant muscle loss in their legs, as well as substantial fat reduction, particularly in visceral fat, which is linked to cardiovascular disease.
Cardiac researchers at the University of Cincinnati found a new cellular pathway that could help develop therapeutic treatments for obesity-related disorders, including diabetes and heart disease. The study identified histone deacetylase 9 (HDAC9) as a potential target for intervention.
Research reveals that morbidly obese people's fat cells reach a storage limit, leading to changes in metabolism that may increase the risk of diabetes and cardiovascular disease. SFRP1 protein production is linked to these changes, which may trigger metabolic syndrome and other health problems.
Children with third-degree burns lose almost half of their stored vitamin E in just three weeks, despite receiving high-calorie diets. This rapid depletion may lead to health complications, including peripheral neuropathy.
A recent study published in the American Journal of Clinical Nutrition found that individuals who consume several servings of whole grains per day and limit their intake of refined grains appear to have less visceral adipose tissue, a key factor in cardiovascular disease and type 2 diabetes. The study observed a 10% lower VAT volume in...
Scientists have identified 80 different proteins produced by human fat cells, including six new proteins and 20 previously undetected ones. These findings suggest that fat cells play an active role in hormone secretion and may contribute to diseases like heart disease and diabetes.
Researchers found that increased abdominal fat increases the risk of metabolic disease, while fat gain in the thighs lowers the risk. The study challenges the concept that the number of fat cells remains stable in adults and suggests a potential protective effect of lower-body fat cells.
A University of Georgia study suggests that mothers who consume a diet high in trans fats double the likelihood that their infants will have high levels of body fat. Infants whose mothers consumed more than 4.5 grams of trans fats per day while breastfeeding were twice as likely to have high percentages of body fat.
A five-year study found that teenagers who increased their screen time had the greatest increases in percent body fat, while those who decreased their screen time had the lowest gains. The study suggests that public health strategies to reduce overall screen time among youth could be beneficial.
A University of Alberta study discovered that muscular heart failure patients with more muscle mass tend to have better nutritional status and reduced severity of the disease. Higher body fat is associated with increased inflammation and reduced exercise capacity, suggesting a potential benefit from having lower body fat.
Researchers found an association between physical fitness and lower metabolic risk factors, such as triglycerides and blood glucose levels, in college students. Even those with higher than desirable body fat percentages can benefit from exercise to reduce chronic disease risk.
Researchers discovered that low-intensity ultrasound therapy can improve the survival and function of tissue grafts after surgery. The treatment increased cellular activity, reduced waste buildup, and enhanced molecular motion, leading to better outcomes for patients undergoing various surgical procedures.
A study published in the International Journal of Obesity found that male and female fat cells have distinct genetic profiles, which may contribute to differences in fat storage patterns. The researchers used mice with different sex hormone levels to determine whether hormones play a role in fat distribution.
Researchers have developed a microscope-based cell scanner to measure physical parameters in Petri dishes, allowing scientists to investigate fat cells at the cellular level. This tool enables rapid assessment of individual cell changes under experimental conditions, providing clues about treatment toxicity or effectiveness.
Researchers found that chokeberry extract reduced body weight, improved blood glucose regulation, and decreased inflammation in prediabetic rats. The study suggests that chokeberry's antioxidant properties may help modulate genes associated with adipose tissue growth and inflammatory pathways.
A new technique using tissue from below-the-waist 'love handles' improves cosmetic breast reconstruction in slim, athletic cancer patients. The method is less complicated than other options for surgeons and turns out to be effective in all 12 patients who underwent the procedure.
A Rice University researcher has developed a natural extracellular matrix from adipose cells that supports the growth of living cells into tissues. The substance, called Adipogel, has been proven effective for growing liver cells and may be used to repair damaged organs in the future.
Researchers found that a certain form of body fat inflammation is necessary for fat cell turnover in lean, healthy individuals. This challenges the theory that inflammation in adipose tissue only causes insulin resistance and type 2 diabetes.
Researchers found that patients with larger volumes of epicardial fat tend to have more dangerous atherosclerotic plaques, which can lead to active buildup in coronary arteries. The study also showed that epicardial fat volume correlates with ischemia during nuclear stress tests.
A recent study by Dr. Richard Kremer found that nearly 60% of healthy young women had insufficient vitamin D levels, leading to increased body fat and decreased muscle strength. The research highlights the importance of vitamin D in maintaining overall health and suggests a potential link between low vitamin D levels and various diseases.
A study by American Heart Association found that organized physical activity is associated with better academic performance, lower body fat levels in adolescent girls, and improved overall health. The research suggests that encouraging regular physical activity can lead to healthier, happier, and smarter children.
Researchers found evidence that fat tissue contains functional hematopoietic stem and progenitor cells, which can regenerate and develop into various cell types. The study suggests that adipose tissue may be a valuable alternative source of these cells, potentially replacing bone marrow transplantation in the future.
Researchers found that college football linemen are at risk of obesity, insulin resistance, and metabolic syndrome due to their high body fat percentage. The study suggests that athletes concerned about maintaining a large size should prioritize healthy weight management and nutrition strategies.
A new study by a European research team has found that obese people have high levels of the molecule CXCL5, produced by fatty tissue cells. This discovery could lead to an experimental treatment aimed at inhibiting the action of CXCL5 to protect against type 2 diabetes.
Researchers found that dialysis patients with very low body fat are at a higher risk of death compared to those with average or high body fat percentage. The study suggests that body fat may be protective for dialysis patients and contradicts the 'obesity paradox' theory.
A new study found that South Asians are more likely to develop insulin resistance and type 2 diabetes due to their body composition, specifically higher total body fat and lower muscle mass. Researchers measured insulin levels in four ethnic groups and discovered a strong association between body fat distribution and diabetes risk.
A new study reveals that angiopoietin-like protein 2 (Angptl2) is a primary contributor to chronic inflammation in fat tissue, exacerbating conditions like diabetes and cardiovascular disease. Elevated Angptl2 levels have been found in obese individuals and those with insulin resistance.
Researchers found that excess liver fat is linked to metabolic problems such as insulin resistance and high blood triglycerides. Losing weight can reverse fatty liver disease, with even brief calorie restriction showing significant reductions in liver fat.
A study found that obese individuals and those with pre-diabetes have high levels of SPARC, a protein linked to fat tissue scarring. This scarring can prevent proper fat storage, increasing the risk of type 2 diabetes.
A University of Iowa study found that kids who were active at age 5 had less body fat by ages 8 and 11. Even small increases in physical activity, such as an extra 10 minutes per day, can make a difference in protecting against excessive fat gains.
A large abdominal wall lipoma caused bowel obstruction in a patient with Proteus syndrome. Excision of the lipoma improved bowel passage and reduced symptoms. The treatment was successful, allowing the patient to continue medical treatment on an outpatient basis.
Researchers create mathematical model to predict optimal blood vessel size for tissue transfer, ensuring successful flap transfer and reducing failures. The model takes into account variables such as oxygen pressure and capillary spacing to provide a more accurate estimate of required blood vessel diameter.
Ben-Gurion University researchers have identified a key signaling pathway in intra-abdominal fat that contributes to obesity-related disorders. The study found that this pathway is activated in response to fat accumulation in the abdomen, correlating with increased cardio-metabolic risk and whole-body insulin resistance.
A study found that safflower oil supplements reduced trunk fat in obese postmenopausal women with Type 2 diabetes, while CLA supplementation lowered total body fat and BMI. Both oils also improved fasting blood sugar levels.
Conventional body fat measurements overestimate obesity in African-Americans compared to Caucasians of the same age and weight. The study suggests that muscle mass may be higher in Blacks, which could explain the discrepancy.
A new study found that hormone therapy combined with physical activity significantly reduces belly fat and body fat percentage in postmenopausal women. The research, which included 34 healthy women, showed that active women had lower waist measurements and better cholesterol levels after 4 months of hormone replacement therapy.
Researchers found that curcumin, a compound in turmeric, suppresses angiogenic activity in mice fed high-fat diets, leading to reduced fat tissue growth and lower blood cholesterol levels. The study suggests potential benefits for preventing fat tissue growth in humans.
A study found that teens with lower vitamin D intakes had higher body fat and visceral fat percentages, while those with adequate intake had lower body fat and visceral fat. Researchers suggest that encouraging teens to consume enough vitamin D through diet or supplements may promote a healthy body as they grow and develop.
Researchers at the Salk Institute found a protein called CREB that promotes insulin resistance in obese mice. Blocking CREB's activity improved insulin sensitivity and reduced inflammation, suggesting a potential therapeutic target for type II diabetes. The study provides hope for new treatments that don't require weight loss.
Researchers at UIC will enroll 500 men with early-stage prostate cancer to investigate the biological factors behind poorer outcomes in obese patients. The study aims to identify new approaches to preventing prostate cancer recurrence or progression after treatment.
Researchers have successfully used stem cells to grow on a scaffold made from tissue extract, overcoming two key challenges for organ transplantation. This breakthrough enables the creation of bioengineered organs that can be transplanted without rejection.
A study by University of Cincinnati researchers found that high-fat diets can cause inflammation in fat tissue surrounding blood vessels, potentially leading to cardiovascular disease. The study suggests a direct link between poor dietary habits and inflammation of blood vessels, independent of weight gain or cholesterol levels.
A study of 22,211 people found that abdominal obesity increased the risk of migraine headaches in those aged 20-55, especially in women. Losing weight around the stomach area may be beneficial for reducing migraine risk in this age group.
UT Southwestern researchers discovered that mice without the AGPAT2 enzyme accumulated excessive liver fat, leading to metabolic complications. A fat-free diet reduced liver triglycerides by approximately 50% in these mice.
A new study by UC Berkeley researchers reveals that disabling a key enzyme in fat cells allows mice to overeat without gaining weight. The enzyme, AdPLA, plays a crucial role in regulating fat metabolism and body weight, making it a promising target for obesity treatment.
Researchers found that irradiation damages fat tissue in mice, reducing its weight and size, and altering its ability to support reconstruction. Additionally, a study on multiple sclerosis found that CXCL1 decreases disease severity by promoting remyelination. A new molecule, FPR-2, has been identified as a potential anti-inflammatory ...
Researchers at Mayo Clinic found a strong association between dense breasts and increased breast cancer risk, citing tissue composition differences between dense and non-dense tissue. Dense breast tissue contains more epithelium and stroma, and higher aromatase enzyme levels than non-dense tissue.
Researchers at UT Southwestern Medical Center have found immature fat cells embedded in blood vessel walls that can grow into adult monsters with excess calories. These cells, called progenitor cells, could be used to treat obesity, diabetes and other metabolic conditions by isolating them from unwanted fat.
A new study from the University of Cincinnati found that Bisphenol A (BPA) suppresses a key hormone, adiponectin, which regulates insulin sensitivity and puts people at risk for metabolic syndrome. The study used fresh human fat tissues and found that BPA exposure resulted in suppression of this hormone.
A recent study published in Obesity found that having excess fat around the heart may increase the risk of heart attacks. Researchers discovered that the volume of pericardial fat was related to the development of calcified coronary plaque, a marker for increased cardiovascular risk.
A University of Missouri study found that Weight Watchers participants lost an average of 5% body weight, but mostly lean tissue. Fitness center members, despite little weight loss, improved health by reducing intraabdominal fat. Group support is crucial for success in both programs.