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Development of a definition of Long COVID

Researchers identified 37 symptoms across multiple pathophysiological domains that are more common in SARS-CoV-2 infected participants at six months post-infection. A preliminary rule for identifying postacute sequelae of SARS-CoV-2 infection (Long COVID) was derived from a composite symptom score and requires further refinement.

SourceJAMA Network·JournalJAMA·DateMay 25, 2023

Life stressors may contribute to multiple sclerosis flares, disability

A Michigan Medicine-led study reveals that life stressors across the lifespan, including childhood trauma and adult abuse, contribute significantly to worsening health and functional outcomes for people with multiple sclerosis. The findings highlight the importance of analyzing the impact of life stressors on MS patients.

SourceMichigan Medicine - University of Michigan·JournalBrain and Behavior·TypeData/statistical analysis·DateMay 24, 2023

Two thirds of childhood physical abuse survivors are psychologically flourishing in adulthood

Research published in Children and Youth Services Review found that approximately two-thirds (63%) of adult survivors of childhood physical abuse are in complete mental health. Barriers to achieving this include a lack of social support, chronic pain, and a history of mental illness like depression or substance use disorders.

SourceUniversity of Toronto·JournalChildren and Youth Services Review·TypeSurvey·DateMay 23, 2023

The aging mouse prostate: kinetics of lymphocyte infiltration

Researchers tracked immune cell clusters in the aging mouse prostate using highly multiplexed immune profiling. Early adulthood sees myeloid cells, while between 6-12 months old, there's a profound shift to T and B lymphocyte-dominance. The study reveals new insight into prostatic inflammaging and the window for interventions.

SourceImpact Journals LLC·JournalAging-US·TypeComputational simulation/modeling·DateMay 23, 2023

Lesbian, bisexual women more likely to have worse heart health than heterosexual women

A new study found that lesbian and bisexual women are less likely to have ideal cardiovascular health scores compared to heterosexual women. In contrast, gay and bisexual men were more likely to have ideal cardiovascular health scores. The study highlights the need for prevention strategies among sexual minority adults in France.

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateMay 17, 2023

Wakefulness-promoting agents effective for excessive daytime sleepiness but patients may discontinue due to side effects

Researchers found that solriamfetol, armodafinil–modafinil, and pitolisant reduce excessive daytime sleepiness in patients with obstructive sleep apnea already using conventional therapy. However, patients may be more likely to discontinue the use of these medications due to adverse events including headache, anxiety, and insomnia.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeLiterature review·DateMay 8, 2023

Can internet usage help protect against dementia?

Researchers found that regular internet users had approximately half the risk of dementia compared to non-users, regardless of factors such as education and age. The study suggests that online engagement may help develop cognitive reserve, which can compensate for brain aging.

SourceWiley·JournalJournal of the American Geriatrics Society·DateMay 3, 2023

Trends in the prevalence of stroke

A nationally representative sample of community-dwelling adults found that stroke prevalence remained stable overall, but increased among men. The study's estimates underestimate the total burden due to institutional settings not included in National Health and Nutrition Examination Surveys.

SourceJAMA Network·JournalJAMA Neurology·DateApr 24, 2023

USPSTF statement on screening for skin cancer

The USPSTF finds the current evidence is insufficient to assess the balance of benefits and harms of visual skin examination by a clinician to screen for skin cancer. Skin cancer is the most commonly diagnosed cancer in the U.S., with melanomas causing the most skin cancer deaths.

SourceJAMA Network·JournalJAMA·DateApr 18, 2023

Black women’s childhood symptoms of disordered eating predict symptoms in adulthood

A new study finds that childhood symptoms of disordered eating are predictive of symptoms in adulthood for both Black and white women. Black women's symptoms were predicted by earlier ages compared to white women, suggesting cultural and psychological factors may influence symptom presentation.

SourceAssociation for Psychological Science·JournalClinical Psychological Science·TypeMeta-analysis·DateApr 12, 2023

Assisted reproduction kids grow up just fine – but it may be better to tell them early about biological origins, twenty-year study suggests

A landmark study by University of Cambridge researchers found no difference in psychological wellbeing or quality of family relationships between children born through assisted reproduction and those born naturally. However, mothers who disclosed their child's origins early on reported more positive relationships and lower anxiety and ...

SourceUniversity of Cambridge·JournalDevelopmental Psychology·DateApr 12, 2023

Readers found to rely on word spelling rather than sound in reading

A study published in the Journal of Experimental Child Psychology found that Russian-speaking readers, including both children and adults, rely on orthographic information during parafoveal pre-processing. The participants were able to recognize words with incorrect letter order more easily than those with pseudohomophones.

SourceNational Research University Higher School of Economics·JournalJournal of Experimental Child Psychology·DateMar 21, 2023

THE LANCET: Contracting a respiratory infection in early childhood associated with a higher risk of dying from respiratory disease as an adult, study finds

A new study published in The Lancet found that contracting a respiratory infection in early childhood is associated with a higher risk of dying from respiratory disease as an adult. Children who had a lower respiratory tract infection (LRTI) before the age of two were 93% more likely to die prematurely from respiratory disease, account...

SourceThe Lancet·JournalThe Lancet·TypeObservational study·DateMar 7, 2023

Youth overweight a risk factor for blood clots as adult

A University of Gothenburg study of over 37,000 men found that being overweight in childhood and young adulthood significantly increases the risk of venous blood clots later in life. The study also suggests that overweight in puberty has a marked impact on future risks of venous thrombi.

SourceUniversity of Gothenburg·JournalJournal of Internal Medicine·TypeData/statistical analysis·DateMar 2, 2023

More evidence that sugary drinks cause weight gain

A review of dozens of studies found a positive association between sugary drinks and weight gain in both adults and children, with increasing SSB intake linked to greater weight gain over time. Limiting SSB consumption is an effective way to prevent age-related weight gain.

SourceUniversity of Toronto·JournalAmerican Journal of Clinical Nutrition·TypeMeta-analysis·DateMar 2, 2023

Any regular physical activity at any age linked to better brain function in later life

A long-term study found that regular leisure time physical activity at any age is associated with better brain function in later life. Maintaining an exercise routine throughout adulthood was particularly beneficial for preserving mental acuity and memory. The study, which included over 1,400 participants, showed that being physically ...

SourceBMJ Group·JournalJournal of Neurology Neurosurgery & Psychiatry·TypeObservational study·DateFeb 21, 2023