The Donald Pinkel Endowed Chair supports the hospital's CEO, Dr. William E. Evans, in his research and academic programs. This endowment honors St. Jude's first director, who developed a revolutionary approach to treating childhood cancer.
The Japanese vehicle delivers new hardware to NASA's Robotic Refueling Mission (RRM), enabling the demonstration of satellite-servicing activities and cryogen replenishment. The RRM team will work with the Dextre robot to test intermediate steps leading up to cryogen transfer.
A study by Montana State University researchers found that the 25 wildlife crossings on the Trans-Canada Highway in Banff allow grizzly bears to access a prime patch of buffalo berries habitat safely. The crossings also enable bears to move between food, shelter and dispersal areas on both sides of the highway.
Scientists at the University of Bristol found significant differences in viral proteins for all four DENV types, which may impact anti-viral therapy design. This discovery could lead to more effective treatments for dengue disease, a mosquito-borne infection affecting millions worldwide.
Consumers of grapes and grape products have increased intakes of essential nutrients, including vitamin A, C, fiber, calcium, magnesium, and potassium. This study suggests that incorporating grapes into one's diet may lead to healthier dietary patterns and improved nutrient intake.
Scientists have unexpectedly created two differently colored crystals from one chemical, revealing new insights into agostic bonds crucial for industrial catalytic reactions. The discovery provides valuable information for making plastics and fuels.
Researchers have developed a new laboratory model to study hepatitis C by infecting monkey stem cells with the virus. The model may lead to new treatments and vaccines for the disease, which affects over three million people in the US.
A study of gene expression in five closely related mouse species reveals the first steps of evolution in gene regulation. The research found that transcription-factor binding variation is an important indicator of gene-regulation activity.
The Eastern Pacific Ocean has become extremely active, with NASA tracking Hurricane Gil and two developing tropical low-pressure areas. System 91E is expected to slow down as it approaches the Central Pacific, while Hurricane Gil is expected to weaken over cooler waters and stronger wind shear.
Researchers have developed two new classes of compounds that target the gamma-secretase enzyme to treat Alzheimer's disease. These compounds produce shorter forms of amyloid peptide 38, which do not aggregate into neurotoxic plaques. Early-onset hereditary forms of Alzheimer's may be linked to mutations in the APP protein gene, leading...
A new Florida State University study has found a significant link between physical fights and IQ decline in teenagers. After two fights, boys experience an average IQ loss of 1.62 points, while girls lose an average of 3.02 points.
Researchers from Drexel University present findings on Northern Pine Snake population decline due to road mortality in New Jersey. Climate change may impact their behavior, while baby snake mazes and counting tongue flicks shed light on early life stages.
Researchers from UC Riverside and international partners discover a new mineral, cubic boron nitride, named qingsongite, which has unique properties resembling those of diamond. Qingsongite was found in the southern Tibetan mountains under extreme conditions and has been officially approved by the International Mineralogical Association.
Researchers found that a specific gene polymorphism is associated with an increased risk of ischemic stroke in the Han Chinese population. The study identified the -607C allele as a strong risk factor for ischemic cerebrovascular disease, while the A allele may provide protective effects.
A new process, dubbed 'bio-inspired approach to thermal control,' has been developed by University of Toronto professor Ben Hatton and his colleagues. This technique involves attaching optically clear, flexible elastomer sheets to regular glass window panes, resulting in a 7-9 degree cooling effect. The innovation could lead to signifi...
The article highlights the need for a national 'Mental Health Pathway' to enable paramedics to provide appropriate care for patients with mental health issues. The proposed pathway aims to reduce admissions and re-attendance while improving care for patients.
Researchers at Queen Mary University of London discovered that omega-3 fatty acids selectively inhibit the growth of malignant and pre-malignant cells without affecting normal cells, suggesting potential use in cancer treatment and prevention. Further research is needed to define therapeutic doses.
A new study published in The Annals of Thoracic Surgery found that oversized donor lungs are associated with a 30% increased chance of survival one year after the operation. The researchers analyzed data from over 4,500 double lung transplants and single lung transplants performed between 2005 and 2010.
Researchers found a link between spontaneous mutations and impaired neurogenesis in the prefrontal cortex of people with schizophrenia. The study suggests that genetic damage can disrupt brain development and lead to early signs of the illness, such as impaired executive functions.
Researchers identified Skp2 inhibitor that blocks malignancy-promoting effects, shrinks tumors in preclinical studies. The compound suppresses prostate cancer stem cells, which play a role in cancer initiation and progression.
Tropical Storm Jebi developed on July 31 and is now filling half of the South China Sea. NASA satellite data shows strong winds and heavy rainfall in a band of thunderstorms southwest of the center.
A study published in Cell has confirmed that non-coding DNA, previously considered 'junk', plays a crucial role in regulating cell development. The researchers found that certain white blood cells use introns to control the activity of genes involved in their function.
A study by Carnegie Mellon University's George Loewenstein found that Americans struggle to comprehend traditional health insurance concepts like deductibles and co-insurance. A simplified insurance plan with copays appealed more to consumers, who were better able to compute costs and make informed decisions.
Researchers discovered a new molecular pathway causing heart failure and showed that JQ1 blocks this pathway to protect the heart. The compound works within the cell's nucleus, preventing damaging stress responses.
Researchers discovered a protein linked to cognitive impairments in Angelman syndrome, a condition characterized by autism, intellectual disability, and motor abnormalities. The study found that reducing the expression of this protein improved cognitive function in Angelman syndrome model mice.
A study on postpartum sexuality found that partners of new mothers experience changes in sexual desire due to factors like fatigue and stress related to caring for a new baby. The research highlights the importance of considering the co-parent's perspective, as their sexual health can be related to each other regardless of the cause.
Researchers found that a non-invasive ultrasound treatment can prevent acute kidney injury in mice by stimulating an anti-inflammatory response. The therapy, which uses sound waves to activate the immune system, showed promise as a potential prevention method for patients at risk of kidney damage after surgery.
Researchers found genetic associations for four odors: malt, apple, blue cheese, and β-ionone. The study suggests that individual sensitivities to these compounds determine unique smells experienced in foods and drinks.
The LSU Health Sciences Center New Orleans School of Dentistry has been awarded a $1.8 million grant to educate dental students about caring for HIV/AIDS patients and provide dental services to this population. Over 2,000 patients received dental care last year alone, with thousands more provided since the program's inception.
A portable diagnostic device developed by Chinese researchers can travel to patients anywhere in the world, providing an opportunity for early cancer detection. The device uses microfluidics technology and is designed to be low-cost, easy-to-use, and power-independent.
Researchers used iPS cells from a CAMT patient to study the disease, finding that thrombopoietin receptor signaling is crucial for megakaryocyte and erythrocyte production. Compensatory transduction of receptors normalized these processes, highlighting the potential for thrombopoietin-like drugs to treat anemia.
Researchers will study tuberculosis in India, examining co-morbidities such as smoking and malnutrition that increase risk of developing the disease. The joint program aims to identify new diagnostic biomarkers for early detection and targeted interventions.
Researchers have discovered that a small protein chemokine called CCL26 plays a crucial role in the development and severity of asthma. CCL26 induces a greater migration of eosinophils in asthmatic airways compared to healthy volunteers, making it a potential target for new treatments.
A University of Oklahoma-led research team has been awarded a $750,000 grant to develop a novel, self-sustaining energy storage system. The project aims to create nanobatteries that can be charged by photovoltaic systems, increasing capacity and reducing size for increased scientific payloads in satellites and rovers.
Researchers at Scripps Research Institute have successfully synthesized a highly complex, plant-derived compound called ingenol, which has long been of interest for its potential in treating various cancers. The efficient chemical synthesis will enable scientists to investigate the therapeutic properties of ingenol derivatives and pote...
Researchers have identified prolactin as a potential treatment for inflammatory joint disease, reducing chondrocyte death and associated cartilage degradation. A protein called CTHRC1 has also been linked to bone health, suggesting it could be a target for osteoporosis treatment.
A study by the American Society of Nephrology found that moderate chronic kidney disease (CKD) costs Medicare tens of billions of dollars each year. The study estimated that Medicare spending attributable to CKD stages 2 through 4 is likely to exceed $48 billion per year, with costs ranging from $1700 to $12,700 per person per year.
A unique four-point test using clinical variables such as serum albumin levels and white cell count can accurately predict the death risk of patients with C. difficile infections. This method has potential benefits for patients, hospitals, and health services worldwide.
A study found that PET/CT is more sensitive and accurate than bone marrow biopsy in detecting bone marrow involvement in DLBCL patients. The imaging modality also predicted progression-free survival and changed treatment plans for 42% of patients with bone marrow involvement.
Researchers discover human blood stem cells residing in the end of bones have highest regenerative ability, potentially improving bone marrow transplants. The discovery aims to lower donated bone marrow needs while increasing regeneration and reducing rejection rates.
Researchers have established that two individuals, Mitochondrial Eve and Y-chromosomal Adam, shared a similar timeline for their existence, with estimates suggesting they overlapped between 120,000 to 156,000 years ago.
Iran's unique biodiversity and climate have led to the discovery of over 200 Fulgoromorpha species, many found only in Iran. The country's high endemism rate indicates a strong potential for speciation among these insects.
Researchers at Michigan State University found that genetic background affects the outcomes of interactions between genetic mutations about 75 percent of the time. This discovery has huge implications for understanding how genes interact with each other, and may help explain why some people respond differently to treatments.
A new study presented at the American Psychological Association's convention found that people who feel isolated are more likely to make risker financial decisions. The research, led by Rod Duclos, discovered that socially excluded individuals prefer longer odds for bigger lottery payoffs and take greater risks with their finances.
A recent study published in the Journal of Antimicrobial Chemotherapy found that more than 60% of antibiotic prescriptions in the US are for broad-spectrum drugs, which can be ineffective against viral infections. The overuse of these antibiotics contributes to the development of antibiotic-resistant bacteria and side effects.
Researchers at Michigan State University found that evolution punishes selfishness and promotes cooperation. The study, published in Nature Communications, suggests that cooperators are more likely to survive and thrive in the long term due to their ability to communicate and adapt to different opponents.
Dr. Andrew S. Weyrich receives the 2013 William Dameshek Prize for his seminal work on the cellular and molecular causes of blood clots, revolutionizing our understanding of platelet function. His research has far-reaching implications in hematology and beyond.
The CU-Boulder team has developed a solar-thermal system that splits water into hydrogen and oxygen, paving the way for a sustainable hydrogen economy. The system uses concentrated sunlight to drive chemical reactions, producing hydrogen gas with minimal energy input.
Scientists have identified a unique enzyme that is abundant in cancer cells but rare in normal adult tissues. By silencing this enzyme, researchers were able to stop the growth of cancer in laboratory mice without causing harm.
A study published in Cell reveals the key role of bromodomain and extraterminal domain proteins in activating genes contributing to heart failure. BET-inhibiting drugs show promise as a new treatment avenue.
Researchers at Monash University have developed a new strategy for engineering supercapacitors, making them viable for widespread use in renewable energy storage and electric vehicles. The device achieves an unprecedented energy density of 60 Watt-hours per litre, comparable to lead-acid batteries.
A study published in the Journal of Clinical Investigation identifies Olfm4 as a potential therapeutic target for Chronic Granulomatous Disease (CGD) patients. Deletion of Olfm4 in mouse models protected against Staphylococcus aureus infections, including community-associated MRSA strains.
Researchers at National University of Mexico found that prolactin can prevent chondrocyte death and associated cartilage degradation in rheumatoid arthritis models. Prolactin treatment reduced inflammation, bone erosion, joint swelling, and pain in rat models.
A University of Maryland-led research team found a specific class of inhibitory neurons controlling the timing of synaptic plasticity, which regulates amblyopia. The discovery offers hope for treating amblyopia late in life by targeting the NARP protein.
Jocelyn Millar, a professor of entomology at UC Riverside, has been elected a fellow of the Entomological Society of America (ESA) for his outstanding contributions to entomology. He is recognized internationally as an expert in chemical ecology and has developed practical applications for detecting and managing insect populations.
A new ultrasound patch has been shown to significantly accelerate healing in patients with venous ulcers, a type of chronic wound that affects millions. The patch, developed by researchers at Drexel University, delivers low-frequency ultrasound directly to wounds and was found to reduce wound size in just four weeks.
Researchers have discovered a key protein called LIN28 that triggers malignant germ cell tumors, a type of cancer affecting the testes and ovaries. By targeting this protein, scientists hope to develop new therapies with less severe side effects.
Researchers at Scripps Research Institute have discovered a new type of chemical modification that affects proteins involved in glucose metabolism, potentially playing a role in cancer and diabetes. The modification acts as a regulator of cellular processes, including the production of glucose.
A new analysis found that people across all social standings accumulate harmful chemicals in their bodies. The study shows strong associations between 18 different chemicals and poverty ratings, with individuals from higher incomes having larger amounts of toxicants like mercury and benzophenone-3.
Scientists discovered that certain sugars can control the timing and placement of minerals used to produce hard structures like shells and exoskeletons. The research proposes a theory on how charged and uncharged sugars can create these structures, offering potential for new environmental and medical technologies.