A recent analysis found that most cancer drug submissions lack health-related quality of life data and fail the cost-effectiveness test. The study highlights the need for better reimbursement policies to balance costs and benefits of expensive cancer treatments.
Researchers at the University of Nottingham found that drivers often forget seeing approaching motorcycles, leading to fatal crashes. In experiments using a driving simulator, drivers failed to recall critical approaching vehicles on up to 15% of occasions.
Megan Young, MD, assistant dean and geriatrics professor at Boston University School of Medicine, received the 2019 Women Physicians Section Inspiration Award. She is known for her infectious enthusiasm, thoughtful approach to teaching, and dedication to mentoring students.
A study of 69 individuals with obsessive-compulsive disorder (OCD) reveals that conflict-related brain activity in 36 regions predicts successful exposure-based psychotherapy. The findings provide new insights into the neural mechanisms underlying OCD and support a tailored treatment strategy.
The new national guideline provides evidence-based treatment options for people with severe opioid use disorder, including injectable opioid agonist treatment with prescription heroin and hydromorphone. The guideline aims to reduce overdose deaths by supporting health care providers in delivering life-saving treatments.
A study found that older adults with chronic obstructive pulmonary disease (COPD) are twice as likely to use prescription synthetic oral cannabinoids compared to those without COPD. This raises concerns about the potential dangers associated with this medication class, particularly in subgroups at heightened risk for adverse events.
A study published in Annals of Neurology found that the spread of seizures through the brain can be suppressed by a
Researchers at Ohio State University have found a new method for harnessing thermal energy by exploiting paramagnetic particles, which can produce spin and generate electricity. This breakthrough could lead to the development of more efficient thermoelectric materials and energy harvesting technologies.
Russian and French scientists confirm Karla crater is an impact structure through paleomagnetic, petromagnetic, and geochemical samples. The study was conducted by researchers from Kazan Federal University and CEREGE, France.
The research focuses on improving oil recovery efficiency through innovative integrated methods and polymer solutions. Laboratory experiments demonstrate the significant influence of mineral skeleton properties on polymer viscosity, highlighting the importance of optimal concentration selection.
Tropical Storm Kiko exhibits a tight circulation center with low clouds and deep convection. The storm is forecast to strengthen briefly before weakening and potentially becoming a remnant low later this week.
A study found that only 4% of adolescents with nicotine use disorder received counseling, and 1.2% were prescribed medications to help them quit. Medical professionals are largely missing opportunities to intervene and prevent long-term health consequences of nicotine use disorder.
A new study finds that kids who specialize in a chosen sport tend to engage in higher levels of vigorous exercise, increasing their risk of injuries such as stress fractures, tendinitis, and ACL tears. The study suggests moderating the amount of time young athletes spend engaging in vigorous physical activity can help mitigate this risk.
A new study framework improves and expands current practice in fossil color reconstruction by incorporating chemical signatures of different pigments. This framework provides a reliable and repeatable approach to test fundamental hypotheses related to animal physiology, ecology, and behavior.
Ancient rauisuchian fossils found in southern Africa reveal that these croc-like predators fed on vegetarian dinosaurs during the Triassic period. The discovery sheds light on how these carnivores thrived in a region close to the Antarctic Circle, challenging previous assumptions about their physiology.
The study reveals climate models may overestimate aerosol particle numbers by a factor of 4 to 7 and underestimate radiative energy scattering by a factor of 2 to 5. Sea-spray aerosol production is closely tied to sea-surface temperature and phytoplankton-related biomass.
Increasing nut consumption by half a serving a day may help stave off gradual weight gain, according to researchers. Substituting unhealthy foods with nuts was associated with lower risk of obesity and weight gain.
The report examines wind energy impacts on sensitive wildlife, citing the need to balance wildlife conservation with rapid greenhouse gas emissions reductions. It highlights areas where further research is needed to minimize wind turbine effects on birds and bats.
A study by University of Michigan wildlife ecologist Nyeema Harris found that human pressures on mammals in West African protected areas are driven primarily by livestock grazing and forest product gathering, not poaching. The research highlights the need for conservation efforts to incorporate livestock husbandry into management plans.
A $1.2M grant will establish a network of recirculating aquaculture systems to produce Atlantic salmon in the US, increasing sustainability and reducing imports. The project aims to develop environmentally friendly land-based systems that can replace imported seafood, promoting domestic production and reducing trade deficits.
A team of scientists developed a technique using light to activate an Iridium-based compound that cuts off the 'power source' in cancer cells, even under hypoxia. This method could reduce side effects and potentially immunize against future cancers.
A study published in Nutrition and Cancer found that consuming sofrito, which includes onions and garlic, was associated with a reduced risk of breast cancer. Women who ate sofrito more than once per day had a 67% decrease in risk compared to those who never ate it.
A recent study found that domestic cats bond with their owners in a way that's surprisingly similar to infants, with about 65% of both cats and kittens classified as securely attached. This suggests that cats' human attachments are stable and present in adulthood.
Researchers identified links between genetic variants and early activation of memory T cells, suggesting problems with regulating this process could lead to immune diseases. The study's findings could help narrow down the search for molecular pathways involved in immune diseases.
This observational study found that insulin treatment was used less frequently among older adults (75-79 years) in poor health compared to those in good health. The study also revealed higher discontinuation rates of insulin treatment among those in poor health, suggesting potential implications for diabetes management.
Doctors argue that UK TV advertising regulations on unhealthy kids' foods were weakened due to industry influence. A thematic analysis of public consultations found that commercial interests often took precedence over public health concerns.
The new AR head-mounted display delivers a realistic 3D viewing experience with an enlarged eye-box and increased field of view. It uses pixel beam scanning to keep images in focus regardless of distance, resulting in high-quality images without dispersion.
A new study has revealed a possible role of oxytocin in hypersexual disorder, which affects 3-6% of the population. The researchers found that microRNA-4456 targets genes involved in regulating oxytocin, suggesting its potential as a treatment target.
Research at the Geological Society of America Annual Meeting explores geoheritage, a concept that connects people, landscapes, and geological processes. By preserving America's geoheritage, communities can experience local economic benefits through geology-related tourism.
Researchers found layers of ancient African dust in volcanic rocks and dune sands on Canary Islands, dating back to 4.8-2.8 million years ago. The findings agree with deep-sea sediments and suggest the Sahara Desert has taken breaks, with wetter periods interspersed with arid times.
The Grand Canyon's 6 millionth anniversary marks a pivotal moment for advancing scientific discoveries, promoting geoscience research and education, and inspiring millions of visitors. Recent research reveals new insights into the formation of the North American continent and the diversity of animal life.
Researchers used machine learning to identify previously unidentified cave entrances in a densely vegetated area of Belize. The computer program successfully picked up smaller caves that were invisible to the naked eye, and confirmed the existence of several large surprise finds, including a collapsed cave complex.
Wildfires can lead to significant impacts on soil infiltration, triggering flooding and erosion. Sediment flows can carry large amounts of debris downstream, posing a threat to reservoirs. Researchers are developing new models to predict the risks of post-wildfire sediment on reservoirs.
The European Society of Cardiology emphasizes the importance of preventing cardiovascular disease in children, who are already at risk due to sedentary lifestyles and unhealthy diets. The SBC Goes to School project aims to educate 63,000 students through teacher-student monitors, promoting exercise and healthy eating habits.
A study published in the American Journal of Roentgenology found that diagnostic radiologists with lifetime ABR certificates were significantly less likely to participate in Maintenance of Certification (MOC) programs. Participation rates were only 13.9% among those with lifetime certificates, compared to nearly universal participation...
The study reveals how cholesterol is incorporated into cells through a previously unknown pathway, providing new understanding of cellular function. The discovery has significant implications for the regulation of cholesterol uptake and potential applications in treating diseases such as cardiovascular disease.
A new study by Dr. Norman Lee and his team uses a performance index and treadmill system to measure how well flies respond to different cricket songs. The findings provide insights into the sensory basis of song recognition, signal discrimination, learning and memory in eavesdropping enemies.
Researchers at Penn Medicine have developed a vaccine that protects against genital herpes, with almost all animal subjects exposed to the virus showing sterilizing immunity. The vaccine stimulates three types of antibodies to block the virus from entering cells and ensure innate immune system protective functions are not turned off.
Researchers from SUTD have developed a holistic approach that applies data-driven methods in design search and optimization for additive manufacturing (AM) products. The new method uses surrogate models to rapidly narrow down the high-dimensional design space, enabling designers to explore millions of design alternatives.
A recent UCSF study revealed that unauthorized immigrant recipients of liver transplants in the US have similar three-year survival rates as US citizens. Despite this, disparities in access to life-saving organs vary widely by state due to policies and provider attitudes.
Climate change and increased demand for energy may lead to a scarcity of water resources for power plants in developing parts of Asia. The study analyzed existing and planned coal-fired power plants and found that there may not be enough water to cool them, particularly under scenarios with higher global temperatures.
Researchers from the University of Copenhagen and Memorial Sloan Kettering Cancer Center have discovered six proteins essential for directing PRC2 to specific areas in the genome. These findings provide insight into how cells maintain their identity, normal embryonic development, and may impact cancer treatment.
Researchers found that certain flavored e-cigarette flavors, even without nicotine, can exacerbate asthma symptoms and increase tissue scarring. Flavors like Black Licorice and Banana Pudding were particularly problematic.
The University of Maryland School of Medicine has been awarded a $200 million contract from the National Institute of Allergy and Infectious Diseases to develop and test new influenza vaccines. The research aims to protect against emerging flu strains and improve seasonal vaccines.
New research by University of Sheffield scientists reveals a direct link between surface melting and short bursts of glacier acceleration in Antarctica, with some glaciers moving up to 400m per year. As temperatures continue to rise, this phenomenon is expected to become more common, affecting sea level rise predictions.
Researchers have applied a novel method to model bacterial colony growth, replicating fractal patterns observed in nature. The study used agent-based modeling to simulate the behavior of bacteria, varying parameters such as cell division speed and mechanical forces.
Biochemists at Nagoya University have found a way to selectively kill Pseudomonas aeruginosa bacteria using a hijacked haem acquisition system that targets other dangerous bacteria, providing an alternative treatment strategy for resistant infections.
Researchers at Michigan State University are using $2.8M in NIH grants to study the piRNA pathway and its role in controlling male fertility. They hope to identify new targets for male contraception, addressing a significant reproductive health issue affecting one in ten couples.
Researchers found that surgical intervention for sleep apnea in children does not significantly improve behavior, cognitive performance, or symptoms of attention deficit hyperactivity disorders. The study suggests alternative explanations for improved outcomes, shedding new light on a widely performed pediatric surgical procedure.
An interdisciplinary team of Indiana University scientists found a link between healthcare industry payments to medical providers and their billed medical costs, with a 10% increase in industry payments associated with 1.3% higher medical costs and 1.8% higher drug costs.
A new shock classification scheme has been validated in a retrospective study analyzing over 10,000 cardiac intensive care patients, revealing a stepwise increase in unadjusted CICU and hospital mortality with each successive SCAI shock stage.
The National Institute of Mental Health (NIMH) has awarded six research grants to develop a learning health care system for the treatment of early psychosis. The grants aim to improve quality of care and patient outcomes while speeding advances in early psychosis services and science.
Researchers have clarified a new synthesis mechanism for transition metal dichalcogenides (TMD), a type of semiconductor atomic sheet. The breakthrough enables the large-scale integration of atomic-order materials, paving the way for next-generation flexible electronics.
A recent study published in Nature Communications found that a circular RNA called circFndc3b plays a critical role in tissue repair after a heart attack. The RNA acts like a 'sponge' to bind harmful molecules, preventing cell death and promoting vascular growth, which aids the repair process.
Researchers developed a nano-tomographic technique to detect invisible properties of nano-structured light landscapes in the focus of a lens. This approach enables single, fast, and straightforward camera imaging of these complex light fields.
A recent study examined marijuana use among US adults with and without medical conditions, finding that nearly one-third of adults reported using marijuana in the past year. The study suggests that marijuana use is common across various populations, with potential implications for both medical and non-medical conditions.
A study conducted at 26 Malawi government hospitals found that the national adoption of rugged, low-cost neonatal CPAP devices improved survival rates for newborns admitted with breathing problems. The study showed a 10% improvement in survival after CPAP was available for babies with respiratory distress syndrome.
Using electric shocks accelerates the formation of limb and tail buds in early chicken embryos. The study reveals that concentric rings within the blastula deform in a cascade-like process, inducing each ring to change shape.
A study found that climate change could cause the maple syrup season to shift one month earlier, with eastern North America potentially losing production capacity. The research suggests that areas like Quebec will see increased production, while others may experience declines.
Aerobic microorganisms like Bacillus subtilis natto can reduce oxygen availability, leading to higher steel corrosion resistance in concrete. This process enhances the formation of calcium carbonate, sealing cracks and facilitating self-healing.