Researchers identified glypican-1 protein that prevents cancer cells from spreading to bone, reducing aggressiveness. The study provides a potential new target for future treatments and supports previous findings suggesting the protein's role in preventing tumor growth.
Researchers at UNIGE found that digital initiatives within country offices have the strongest impact on changing ways of working, embedding new skills, and restructuring teams across the UN. The study highlights the power of bottom-up innovation, where ideas can spread from country to country, achieving scale and changing the organizat...
A new synthesized chemical compound demonstrates how introducing diradical systems can alter the properties of carbon nanotubes, including spin states and aromaticity. The findings show smaller singlet state systems exhibit in-plane aromaticity and stability.
Researchers found that tiny hairs on honeybee abdomens reduce friction during movements, conserving energy and reducing wear. This discovery could inspire the design of longer-lasting moving parts.
Researchers from Hiroshima University used a meta-analysis of publicly available transcriptome databases to identify four new genes associated with hypoxia. By combining transcriptomic and bibliometric analyses, they found previously unknown genes that were not well studied in relation to hypoxia.
New research from the University of Arizona suggests that asteroid 16 Psyche may not be as dense or metallic as previously predicted. The findings propose an alternative origin story where 16 Psyche is composed of 82.5% metal, 7% low-iron pyroxene, and 10.5% carbonaceous chondrite.
The CHIME telescope has detected over 500 fast radio bursts, quadrupling the number of known radio bursts. The newly discovered signals reveal two distinct classes: repeaters and one-offs, which are thought to arise from separate mechanisms and astrophysical sources.
A new study analyzing medical evidence on domestic mass shooters in the US finds that a majority of perpetrators have psychiatric disorders without treatment, increasing risk of violence. The researchers identified signs and symptoms of brain illness in 32 out of 35 perpetrators, with most having schizophrenia or other diagnoses.
Researchers develop a new method to create ultrathin functional materials with highly defined structures, using self-organization and photopolymerization. The process produces porous two-dimensional polymers with nearly perfect order, opening up potential applications in filtration, membranes, and other contexts.
Researchers at PPPL have designed a novel X-ray crystal spectrometer to measure fine structure in HED plasmas, revealing their state of matter under extreme conditions. The new spectrometer addresses design challenges such as reducing statistical errors and improving energy resolution for NIF-produced HED plasmas.
A new Arizona State University study has shown that high fat diets can trigger a molecular cascade of events leading to colon cancer through intestinal stem cells. The research found that PPARs, specifically PPAR delta and alpha, play a crucial role in elevating cancer risk by stimulating the metabolism of fats.
Researchers at Kumamoto University developed a new analytical method to detect degraded beta-lactam antibiotics. Cysteine persulfide, a reactive sulfur species produced by bacteria, degrades and inactivates these antibiotics.
Researchers have developed a platform that produces bespoke star-shaped polypeptide nanoparticles, effectively delivering range of therapies including gene therapies. The material accelerates bone tissue regeneration with a six-fold increase in new bone formation.
Researchers achieved giant nonlinearity of UV hybrid light-matter states up to room temperature in a wide bandgap semiconductor material. This breakthrough enables the development of new on-chip ultrafast spectroscopy devices with unprecedented sensitivity.
Improv pedagogy enhances musical learning and social skills, fostering cooperation and uncertainty-faciling
Researchers at UNIST have successfully controlled the physical properties of naturally-formed nanoscale wrinkles in 2D semiconductors. The team developed a hyperspectral adaptive tip-enhanced photoluminescence spectroscopy approach to investigate and control the nano-optical and excitonic properties of wrinkles.
A new study published in the Journal of the American Geriatrics Society found that heart transplant surgery has a similar mortality rate for adults aged 18-69 and 70+, with only minor differences in stroke risk and donor hearts. Advanced age alone should not prevent people from being considered as candidates for heart transplants.
Research reveals people with hyperphantasia have a stronger connection between the visual network and the prefrontal cortices, linked to decision-making and attention. This contrasts with aphantasics, who have lower ability to recognize faces and perform autobiographical memory tasks
The new Gluon Exchange Model (GEM) describes protons as complex systems with virtual quark-antiquark pairs, challenging the concept of stable diquarks. GEM predicts the disintegration of diquarks in certain collisions, offering a new perspective on proton interactions.
Researchers discovered a new bacterium, Dysosmobacter welbionis, present in 70% of the population, which produces butyrate and has anti-inflammatory effects. The bacteria was found to increase mitochondrial activity, lowering sugar levels and weight in mice, suggesting potential for treating type 2 diabetes and obesity.
Researchers at Tokyo Tech developed a flexible device capable of rapidly increasing temperature of target tissues without tissue burning. The device overcomes limitations of existing heat-generating devices and opens up possibilities for wide clinical scenarios including minimally invasive endoscopic surgery.
The AIDS Clinical Trials Group (ACTG) has added BMS-986414 and BMS-986413, two monoclonal antibodies, to the ACTIV-2 outpatient treatment study for COVID-19. The combination therapy aims to improve efficacy, cover multiple variants, and reduce resistance. Participants will receive subcutaneous injections of the antibodies or placebo.
A study evaluating 22 patients with recurrent Anti-hormonal granulosa cell tumors found low-to-moderate FDG uptake and variable ERα/ERβ expression. FES-PET/CT showed promising results in identifying treatment-eligible patients, with stable tumor locations decreasing in size during anti-hormonal treatment.
Research published in Acta Paediatrica suggests that a pregnant woman's mental health impacts the touch behavior of twins and singletons, with maternal depression affecting soothing mechanisms for fetuses. The study also found differences in touch and movement behaviors between singletons and twins.
Panama has expanded its Coiba protected area, covering 98,228.25 square kilometers, to achieve the 30x30 Initiative's goal of protecting 30% of the world's marine surface nine years early. The expansion protects unique underwater mountain ranges and migratory marine species.
Researchers have developed an unconventional method for controlling solid-state spin qubits using anti-Strokes (AS) excitation, which reduces the energy requirement compared to conventional Strokes excitation. This breakthrough enables improved quantum information processing and high-sensitivity quantum sensing capabilities.
Scientists at McMaster University have developed a new treatment approach for people suffering from VITT, combining anti-clotting drugs with high doses of intravenous immunoglobulin. The treatment's effectiveness was shown in three Canadian patients who received the AstraZeneca vaccine and developed VITT.
Researchers found that 75% of medicinal plant services are linguistically-unique and known to one language, highlighting the critical role of indigenous languages in preserving medicinal knowledge. The study suggests that language loss will be even more critical to medicinal knowledge extinction than biodiversity loss.
A recent study suggests that using CPAP therapy for moderate to severe obstructive sleep apnea reduces the risk of heart problems. Patients with untreated sleep apnea are at a higher risk of cardiovascular events, but those who use CPAP have a lower risk.
A new wearable electroencephalogram device gathers reliable sleep data from the ear, measuring neural signature stability over time. The study found a 90.1% classification accuracy for individualized signatures.
Researchers warn that karst aquifers are vulnerable to contamination due to fast infiltration of pollutants during rainfall events. The study highlights the risks of degradable pollutants like glyphosate exceeding safe levels by 19 times.
A model for broaching these issues is described, involving joining, assessment, preparation, and delivery steps. The model provides a framework for counselors to address client concerns about racial, ethnic, and cultural topics.
Researchers found two gene variants associated with an increased risk of triple negative breast cancer (TNBC) in African American women. The ANKLE1 gene variant is protective against TNBC, but a version found in African Americans may be oncogenic. A mutation in the Duffy gene also increases TNBC risk in African American women.
A study by Braxton Boren suggests that prolonged pandemic lockdowns and noise in multiunit housing contribute to increased social tension and isolation. Incorporating virtual reality and spatial audio may help mitigate these effects, improving overall well-being.
A recent study found an association between rideshare use and increased risk of alcohol-associated motor vehicle crash traumas. The research compared traumas and convictions before and after Uber's introduction in Houston, Texas, revealing a significant correlation.
Researchers at Colorado State University discovered that soil microbes can metabolize polyphenols, a breakthrough that could change how we view carbon cycling. The study showed that polyphenols are not just inaccessible to soil microbes, but are actually food sources for them in oxygen-free conditions.
A recent study found that college football teams' performance is associated with both the direction of travel and the time of day when games were played. Away teams playing in the afternoon allowed more points and forced more opponent turnovers than those playing in the evening, while teams traveling eastward threw more interceptions.
Researchers from KIT and universities in Göttingen and Toronto develop machine learning methods to simulate material behavior, achieving high accuracy and speed. Hybrid methods combining machine learning and molecular mechanics are also suggested to accelerate simulations of large biomolecules.
Research found that Filipino-Americans are more likely to be diagnosed with advanced thyroid cancer, while European Americans tend to have early-stage disease. DBP expression was also linked to cancer staging in both groups, suggesting a protective role for the protein.
Studies presented at SLEEP 2021 show a potential model for predicting COVID-19 infection based on sleep duration, quality, and heart rate variability. The 360 smart bed's SleepIQ technology provides individualized sleep health evaluations and outcomes.
A Kaiser Permanente study found that hospitalization rates for heart attacks remained stable during subsequent COVID-19 surges, contrary to initial declines during the pandemic's onset. The research suggests effective public health campaigns encouraged people to seek care, resulting in a rebound of hospitalizations.
A retrospective study of 33,360 patients found a 41% increased risk of Parkinson's disease in those with osteoarthritis. Patients with knee or hip osteoarthritis had a higher risk compared to others.
The COVID-19 pandemic has threatened Chile's defined contribution pension system, undermining its financial foundation and exposing it to political risk. The government's response to the crisis, including emergency withdrawals from pension fund savings accounts, has set a dangerous precedent for using retirement funds for basic needs.
Researchers develop a framework to identify and evaluate feasibility concerns in climate mitigation scenarios, highlighting institutional constraints and socio-cultural limitations. The study applies the framework to IPCC scenarios, revealing that many assume fast decarbonization rates in regions with low mitigation capacity.
An observational study of over 27,000 US veterans found that risk factors like housing problems and financial hardship were not associated with higher mortality rates among those infected with COVID-19. Instead, the study suggests that other factors such as alcohol use and substance abuse may be more closely linked to increased risk.
Research reveals a strong link between hyperhomocysteinemia and migraine with aura in rats, showing elevated HCY levels increase susceptibility to cortical spreading depression. The study suggests timely correction of high homocysteine levels may be beneficial for treating migraine-related symptoms.
Researchers from Nara Institute of Science and Technology discovered that plants can gain heat tolerance through an epigenetic memory mechanism involving JUMONJI proteins. This mechanism allows plants to adapt to future heat stress by 'remembering' how to deal with heat shock genes.
A Curtin study reveals that aspirin, a naturally occurring compound found in willow trees, can improve the survival of grass species important for ecological restoration and sustainable pasture. Low concentrations of salicylic acid applied to seeds can boost plant growth and resistance to stress.
Research finds periodic oscillations in COVID-19 cases attributed to seasonal modulations and reporting bias. Mass gatherings are identified as the main cause of the COVID-19 disaster, while non-pharmacological interventions remain essential for controlling the epidemic.
A new analysis by Massachusetts General Hospital researchers found that COVID-19 disproportionately affected people of color, low-income populations, and those with certain socioeconomic characteristics. The study, based on data from 394,536 patients, highlights the role of structural factors in the pandemic's spread.
Lehigh University engineers use Frontera supercomputer to simulate photovoltaic fabrication and train AI to optimize energy production. Their 'physics-informed machine learning' approach reduces time required to reach optimal process by 40%.
A sea count survey and tagging data revealed an estimated 10,000 harbor seals inhabiting the Northern Inland Waters of Washington State. The study used line-transect methods to estimate the stock size of Phoca vitulina richardii in these waters.
Researchers have calculated that exomoons orbiting free-floating planets could harbor sufficient water to make life possible and sustain it. The study found that the presence of cosmic radiation and tidal forces could keep water in a liquid state, making these systems promising for the detection of life beyond Earth.
Researchers from Mainz University and Fraunhofer Institute collaborate with Iranian and Iraqi partners to provide drinking water to settlements on the Persian Gulf. The goal is to use temperature-sensitive polymer gels to convert seawater into drinking water, enabling an energy-independent process.
Researchers found SARS-CoV-2 on hospital floors and surfaces, especially after patient onset of symptoms. The virus was often accompanied by the bacteria Rothia, which strongly predicted its presence.
Researchers at Berkeley Lab, University of Hawaii, and Florida International University found a new way for free radicals to react, leading to the formation of benzene rings. This discovery could help create more efficient gas engines and reduce air pollution.
A team of scientists has observed direct atomic evidence of the anionic redox mechanism in lithium-rich cathodes, which could lead to breakthroughs in battery technology. The discovery provides conclusive evidence for this mechanism, nearly doubling the energy storage capacity compared to conventional cathodes.
Intranasal COVID-19 vaccines aim to provide both mucosal and systemic immunity, potentially offsetting global vaccination disparities. Despite challenges in studying the mucosal immune system, scientists are working to develop nasal doses of COVID-19 vaccine.
Researchers developed a cell-penetrating peptide to prevent septic shock in animal models. The treatment shows promise in protecting patients with metabolic syndrome and those at risk of severe COVID-19 complications.
Research from Binghamton University finds a higher association between dietary factors and women's mental health compared to men. Exercise is shown to reduce the negative impact of unhealthy foods on mental wellbeing in mature women.