A new study suggests that children under 5 infected with Omicron have a lower risk of severe health outcomes compared to those infected with the Delta variant. The study found that Omicron is 6-8 times more infectious than Delta, but resulted in fewer hospitalizations and mechanical ventilation cases.
Researchers developed a new method, EpiDamID, to analyze single cells and determine the location of modified proteins around which DNA is wrapped. This technique helps understand how PTMs affect gene expression and has implications for early development and disease research.
Researchers found that flash droughts are happening more quickly, with the fastest ones occurring within five days, affecting areas like South Asia, Southeast Asia, and central North America. The study highlights the importance of understanding and preparing for these events.
A new study reveals that leafcutter ants employ complex strategies to maximize the growth of their fungal
Researchers found that warmer and longer autumn conditions made it less likely for green-veined white butterflies to survive winter. The butterflies used more energy under these conditions, which can lead to lasting negative consequences, including reduced fitness.
A preclinical study suggests that SARS-CoV-2 infection can cause ferroptosis in pacemaker cells, leading to cardiac arrhythmias. Researchers used animal models and human stem cell-derived pacemaker cells to demonstrate the virus's impact on these cells.
A study of 3.5 million Medicare decedents found the percentage of dementia diagnoses at end-of-life increased from 35% in 2004 to 47% in 2017. This rise may be attributed to heightened awareness and changes in billing practices.
A research team from City University of Hong Kong developed a multi-functional electrostatic droplet tweezer that can precisely trap and remotely guide liquid droplets on flat and tilted surfaces, as well as in oil mediums. The technology offers precise and programmable droplet manipulation with high velocity and agile direction steering.
Researchers analyzed 3D facial size and shape to quantify sex differences, providing data-driven anatomic guidance for gender-affirming facial surgery. The study shows significant differences in male and female craniofacial features, particularly in brow, jaw, nose, and cheek regions.
Researchers propose a new research paradigm for material studies based on the concept of functional motifs, which are critical microstructure units governing material functions. This approach enables the rational design of new materials with desired properties by understanding the quantitative relationships between structure and property.
A new study found that omega-3 fatty acid supplementation can broadly improve immunotherapy and other anti-cancer drugs in the clinical setting. In mice, diets enriched with omega-3s blocked tumor growth when combined with immunotherapy or anti-inflammatory treatment, indicating possible synergistic anti-tumor activity.
A new study found that common variable immunodeficiency (CVID) affects only one identical twin due to alterations in immune cell-cell communication and epigenome. Researchers identified defects in B cells and other immune cell types, as well as massive epigenetic problems with DNA methylation.
Claire Célérier, a leading expert in household finance, has been recognized by the Bank of Canada with its Governor's Award for her groundbreaking research on financial inclusion. The award provides a $30,000 annual research grant to support her work on innovative financial products and behavioral biases.
A new study from Northwestern University found that once-weekly prednisone treatment improved exercise endurance, increased lean body mass, and reduced weight in obese mice. The treatment also promoted nutrient uptake into muscles and increased adiponectin levels, a hormone that helps protect against diabetes and insulin resistance.
The paper discusses 2D MIMO-OTA testing algorithms for UE and 3D MIMO-OTA testing algorithms for base stations in the MPAC test setup, comparing related algorithms. Key requirements for designing OTA testing systems are also summarized.
A new study by researchers at New York University found that people tend to prioritize men when referring to individuals in general. The study analyzed over 630 billion words from internet web pages using artificial intelligence tools to measure word meanings.
A combination of two biomarkers has been found to identify patients with subcortical small-vessel disease, a common cognitive diagnosis. This discovery improves the potential for treatment and medication development for this patient group.
Researchers project COVID-19 deaths in US states after lifting nonpharmacologic interventions. The study found significant differences in mortality rates among states, highlighting the need for targeted health policies.
A developmental gene found in humans is also present in sea anemones and plays a critical role in their ability to sense touch. This discovery sheds light on the ancient evolutionary roots of human hearing and its connection to other sensory modalities.
The new ACC/AHA/HFSA guideline redefines heart failure stages to focus on prevention, updating treatment options for people with symptomatic heart failure. It recommends blood pressure control, SGLT-2 inhibitor medicines, and healthy lifestyle habits to prevent HF risk factors from developing.
The Eastern North China Craton's destruction led to CO2 outgassing from the deep mantle. High Ca/Al and low Ti/Eu Mg isotopic compositions indicate recycled surface carbonates stored in the lithospheric mantle.
Post-surgery patients exhibit moderate speech disorders affecting all language processing aspects, whereas post-stroke patients display specific phonological deficits. Understanding these differences is crucial for developing targeted therapies.
A gene therapy trial has shown significant reduction in infections and improvement in eczema symptoms in children with Wiskott-Aldrich syndrome (WAS). The treatment, using lentiviral gene therapy, offers a safe alternative to bone marrow transplantation for patients without suitable donors.
Researchers at Northwestern University used CRISPR to identify human genes important for HIV infection in blood cells, finding 86 genes that may play a role in replication and disease. The study proposes a new map for understanding how HIV integrates into the DNA and establishes chronic infections.
A new study suggests that dramatic swings in food intake can have long-term impacts on cardiovascular health and metabolism. Researchers found that rats who experienced cycles of weight loss and gain had reduced heart and kidney function, as well as increased insulin resistance.
A new study reveals that competitive debates lead to increased polarization as individuals persuade themselves of their side's superiority, even if it conflicts with personal beliefs. The results suggest that self-persuasion is a significant contributor to the growing divide in society.
People with positive past attitudes and long-term planning skills are less depressed, sleep better, and handle isolation more easily. Those who focus on short-term plans and have negative past attitudes show signs of depression, poor sleep quality, and mental disorders.
Researchers at the University of Eastern Finland have developed a novel nuclear microRNA, miR-466c, that regulates vascular endothelial growth factor A (VEGFA) expression in response to hypoxia. The drug has commercial relevance for treating ischemic cardiovascular disease by increasing VEGFA levels.
Researchers used NASA's Planetary Spectrum Generator to analyze light from Venus, Mars, and Jupiter, shedding new light on the presence of biosignatures and chemical compounds. The study helps clarify the association between methane on Mars and life, as well as the fate of Martian water.
Researchers at Virginia Tech have found that key parts of the global carbon cycle used to track movement of carbon dioxide in the environment are not correct. The estimate of how much carbon dioxide plants pull from the atmosphere is critical to accurately monitor and predict the amount of climate-changing gases in the atmosphere.
Researchers found severe brain inflammation and injury in COVID-19 patients, with neuron damage and death also present. The study suggests that nonhuman primates can serve as a proxy for understanding human neurological consequences of COVID-19.
A new study finds that climate change will increase the risk of debris flows, flash floods, and extreme rainfall events following wildfires in the western US. By the end of the century, more than 90% of extreme fire events will be followed by at least three extreme rainfalls within five years.
A randomized controlled trial found that community health workers (CHWs) employed by Medicaid plans can help low-income individuals rely less on emergency rooms and more on outpatient care. The study showed significant reductions in acute care visits and costs, while outpatient visits increased among participants who connected with a CHW.
Offline subscription platforms must consider the local market condition to succeed, with variety-seeking customers, differentiated vendor offers, and alleviated price competition being key factors. Platforms also have a dual relationship with vendors, collaborating on services while competing on prices.
Researchers from Georgia Tech have developed a novel tile-based approach to construct on-demand, massively scalable arrays of 5G+ enabled smart skins. The study demonstrates the ability to enhance 5G+ technologies while featuring flexible and conformal capabilities.
Dystonia is characterized by involuntary movements and postures, limiting daily activities. A new study maps specific brain networks for treatment success in patients with cervical and generalized dystonia. The findings reveal distinct stimulation sites depending on the type of dystonia, offering a more targeted approach to improving t...
The March 2022 nTIDE Jobs Report shows employment-to-population ratios for working-age people with disabilities increasing from 33.1% in February to 34.1% in March, a historic high. Labor force participation rates also increased, with workers with disabilities remaining engaged in the labor market throughout the pandemic.
A new study by NIH-funded researchers shows that adolescents with severe substance use disorder symptoms are more likely to develop prescription drug misuse and overdose risks in adulthood. Screening for substance use disorder in teens may help predict adult problems and prevent overdoses.
Researchers from North Carolina State University have released a dataset providing detailed information on COVID-19 vaccine shipments and wastage across the US. The data aims to inform modeling and decision-making to optimize vaccine supply chains.
A new study reveals that nearly half of all older adults now die with a dementia diagnosis listed on their medical record, a 36% increase from two decades ago. This rise may be attributed to better public awareness, more detailed medical records, and Medicare billing practices, rather than an actual increase in the condition.
New research published in Strategic Entrepreneurship Journal suggests that higher unemployment insurance benefits discourage entrepreneurship by disincentivizing business creation and discouraging people from transitioning out of unemployment. Removing profit deduction requirements could encourage more unemployed entrepreneurs to start...
A new University of Michigan study found that most adolescents with severe substance use disorder symptoms continue to struggle with addiction into adulthood. The study's lead author warns that prescribing controlled substances to individuals with multiple substance use disorder symptoms poses safety concerns.
Dendritic cells, or 'sentinel' immune cells, are vital to maintaining the body's immune balance. Researchers have discovered their essential role in treating cancer and severe viral infections by preventing immunopathology.
A new study reports breakthrough bleeding and other period symptoms in non-menstruating individuals after COVID-19 vaccination, highlighting the need to include gender-diverse people in vaccine research. The study found that one-third of respondents reported breakthrough bleeding, with some experiencing significant mental health impacts.
Perseverance mission has recorded the first ever sounds from Mars, showing that the planet is quiet due to low natural sound sources. The rover's microphone captured sounds within the human audible spectrum, including shock waves and helicopter flights.
Researchers have engineered probiotic bacteria to produce the dopamine precursor L-DOPA, a potential treatment for Parkinson's disease. The new approach eliminates side effects and reduces treatment complications, offering a promising alternative to existing treatments.
Researchers found that cichlids and stingrays can perform simple arithmetic operations, such as adding or subtracting one, in the number range of one to five. The fish were trained using a color-based system and showed impressive learning abilities.