Researchers from USTC introduced a 'bubble diode' concept to address the issue of bubble precipitation in fast-charging Zn-air batteries. The design guides the development of bubble-free electrodes, leading to improved energy density, safety and environmental friendliness.
A study published by The BMJ found that ending performance-related payments for NHS GPs in Scotland was associated with a decline in the quality of some aspects of care compared to England. Researchers recommend continuing data collection to monitor the impact of changes on care quality.
Researchers at the University of Michigan have developed a new virtual testing environment that reduces the time and cost of autonomous vehicle (AV) testing by 99.99%. The system uses simulated terrible drivers to create challenging scenarios, allowing AVs to encounter rare safety-critical events in a shorter amount of time.
Two early-career cognitive neuroscientists, Anna Schapiro and Freek van Ede, have been awarded the prestigious Young Investigator Award by the Cognitive Neuroscience Society. Their research focuses on understanding human learning and working memory.
The study resolves a long-standing question about the structure of respiratory supercomplexes in unicellular eukaryotic organisms. Complex II is found to be part of the supercomplex in these organisms, optimizing ATP formation and revealing a surprising variety in supercomplex construction.
Researchers at St. Jude Children's Research Hospital and Rockefeller University have gained a better understanding of the cystic fibrosis transmembrane conductance regulator (CFTR). The new findings reveal how CFTR functions mechanistically and how disease mutations affect its function, paving the way for more effective therapies.
The oxygen-ion battery has an extremely long service life due to its ability to regenerate and store capacity that does not decrease over time. It also solves the problem of fire hazards associated with lithium-ion batteries.
A new study by Linköping University reveals that climate change alters natural greenhouse gas fluxes from streams and lakes, making landscape carbon sinks less effective. The researchers found that increased precipitation and temperature affect the amount of carbon washed into streams and lakes, leading to greater emissions.
Researchers used a monoclonal antibody to reduce circulating IgG levels, allowing for successful gene delivery to the liver and heart via systemic AAV-based gene therapy in mice and non-human primates. The strategy has potential to circumvent neutralizing antibody limitations and expand gene therapy accessibility.
Researchers from CHOP developed a prediction model that determines which newborn babies are likely to experience seizures in the NICU. The model, built using machine learning methods, can predict seizures with over 90% accuracy, particularly in newborns with hypoxic-ischemic encephalopathy.
Researchers found an increase in biologically available nitrogen during the time when marine eukaryotes became dominant, leading to a new era for life on Earth. This discovery links ancient ocean records to the present and beyond, providing context for global changes.
Researchers from Kyushu University found that the single mechanosensitive protein VGLL3 induces fibrosis, thickening and scarring tissue. The study suggests targeting this protein could lead to new treatments against fibrosis.
A study found that prenatal exposure to environmental pollutants contributes to childhood obesity and metabolic disorders. However, the researchers discovered that high levels of vitamin B12 may enhance the obesogenic effect of certain pollutants, while β-cryptoxanthin from oranges or apples may protect against these effects.
Researchers developed a neural implant that restored limb function to amputees and paralysed individuals by integrating with the brain and nerve. The biohybrid device combines electronic components with reprogrammed muscle cells, preventing scar tissue formation and improving signal extraction.
A Danish cohort study found that children born by cesarean section had lower chances of graduating from secondary education, but no significant difference in grade point averages or intelligence scores. Additionally, male CS births were less likely to be drafted into the military.
Researchers discovered that mechanical loading can exacerbate inflammation in aged muscles, hindering healing. However, combining mechanotherapy with anti-inflammatory treatment significantly improves healing in aged muscles.
A new study reveals that 31% of middle-aged people are frail or pre-frail, with frail individuals facing delayed or omitted medical care. Socioeconomic disadvantages exacerbate these disparities, making it challenging for frail, poorer Americans to access healthcare.
A rare strain of Toxoplasma has been found in California sea otters, killing them with severe inflammation and potentially threatening other marine life. The COUG strain was first detected in Canadian mountain lions, and its impact on humans and other animals is unknown.
A new study links shorter telomeres to multiple changes in the brain associated with dementia, including reduced grey matter volume and a thicker cerebral cortex. Longer telomeres were found to be protective, reducing the risk of dementia but not stroke or Parkinson's disease.
A new course at Norwegian University of Science and Technology teaches risk management and resilience in maritime digital security. Despite the importance of training, many deck officers reported uncertainty about handling cyber incidents on board.
A novel sperm sex selection technique has been found to be around 80% effective in producing offspring of the desired sex. The new method is considered safe and its efficacy was determined through a small clinical trial.
Researchers achieved optical switching of a light signal at attosecond speeds, exceeding data transfer speeds by 1 million times. This breakthrough enables the development of ultrafast optical electronics and could increase data processing speed in long-distance communications.
Advances in drilling technology are unlocking geothermal energy's full potential, with supercritical water offering an efficient energy source. Improved drilling methods aim to overcome the financial barrier of deep geothermal exploration, enabling a step-change in power output.
Researchers examine phytoplankton blooms induced by tropical cyclones to predict climate change impacts. The study found a massive bloom in the wake of Cyclone Oma, which occurred once every 1500 years, and may indicate changes in ocean temperatures.
Researchers at Penn Medicine discovered that maintaining nicotinamide adenine dinucleotide (NAD) levels may protect against kidney disease. NAD supplements were shown to be effective in reversing NAD loss and suppressing inflammation in mouse kidneys, suggesting a potential therapeutic target for kidney disease prevention and treatment.
Researchers have developed a new restoration method that utilizes color space-based segmentation to clean up ancient manuscripts. This technique allows for the analysis of previously inaccessible or damaged texts, providing insights into history and culture.
The Academy of Breastfeeding Medicine has released new guidelines to help parents manage night-time breastfeeding in young infants. The guidelines emphasize the importance of mothers sleeping close to their babies and taking measures to minimize nighttime feedings, promoting a more responsive and baby-led approach to breastfeeding.
Researchers have found a potential treatment for osteoarthritis by targeting the GP130 immune receptor, which causes hyper-inflammation in joints. The new compound R805/CX-011 showed promising results in animal studies, reducing joint pain and stiffness, and may lead to Phase 1 and 2A clinical trials.
A study published in the Journal of Experimental Medicine reveals a unique subset of fibroblastic reticular cells in omental milky spots crucial for immune cell recruitment to prevent sepsis. These cells regulate the display of CXCL12, recruiting lymphocytes to sites of inflammation.
A study by Ruhr-University Bochum investigated how 76 prospective biology teachers argue about controversial topics such as mandatory vaccination against COVID-19. The researchers found that the structural complexity of their argumentation was good, but they could include a broader range of content areas and perspectives in their argum...
Researchers found that a plakophilin-2 mutation leads to increased desmosomal protein degradation in ACM hearts, causing structural and functional changes. Studying human heart samples and mice models confirmed the role of protein degradation in ACM development.
Researchers found that the Alba morph in female Colias butterflies evolved once near the last common ancestor over 1.2 million generations ago. The genetic basis of Alba was identified as a regulatory region in DNA, maintained through gene flow and balancing selection.
A recent study found that moderate exercise duration (≥150 minutes/week) improves gut microbiome richness and diversity, with no significant impact from exercise intensity. Additionally, normal-weight individuals showed the most beneficial changes, while overweight individuals' microbiomes were influenced by poor dietary habits.
Researchers have developed a new simulation method to study polarons in 2D materials, which could lead to breakthroughs in OLED TVs and hydrogen fuel production. The study uses quantum mechanical theory and computation to determine the fundamental properties of polarons in 2D materials.
Patricia M. LoRusso, DO, PhD (hc), has been elected as the American Association for Cancer Research President-Elect for 2023-2024, succeeding an unnamed previous president-elect. She is a professor of medicine and chief of experimental therapeutics at Yale Cancer Center and Smilow Cancer Hospital.
The new test helps detect new HIV infection and follows current guidelines for testing patients on HIV prevention medication. The study identified successful efforts and opportunities for process improvement during the first three months of implementation.
Researchers found that miR-145 suppresses cervical cancer cell growth and inhibits aerobic glycolysis. Targeting miR-145 is expected to be an effective strategy for cervical cancer treatment, according to the study.
A new study from PetDx shows OncoK9 performs similarly to its landmark clinical validation study in real-world settings, detecting 26 types of cancer in high-risk dogs. The test also provides peace of mind for veterinarians and families by detecting cancer in over 94% of negative cases.
A study of over 6,000 participants found that those consuming more than 550 milligrams of magnesium per day had a brain age approximately one year younger by 55 compared to those with normal intake. Increased magnesium intake was also associated with lower risk of dementia and better cognitive function.
Researchers have developed a novel process to convert nitrogen and hydrogen into ammonia at ambient temperature and pressure with high energy efficiency. The process uses a solid polymeric electrolyte and eliminates the need for purification, producing pure ammonia gas.
An international team developed a novel method for evaluating AI interpretability methods to decipher the basis of AI reasoning and possible biases. The approach helps users understand what influences AI results and whether they can be trusted, especially in medical applications where AI-powered decisions can impact health and lives.
The research demonstrates that low concentration ether-based electrolyte can successfully endure the long-term high voltage operation of practical LMB. The findings show that regulating solvation structure and adjusting surficial electric double layer can prevent degradation and improve performance.
Researchers from Kessler Foundation found that transcutaneous spinal stimulation does not interfere with implanted intrathecal baclofen pump delivery systems. However, communication between the pump and its interrogator may be briefly affected due to electromagnetic interference.
A recent study found that adolescents living in areas with healthier built environments are less likely to be obese and have healthier eating habits. The study suggests that strategies for addressing childhood obesity should focus on improving built environments.
Researchers are conducting a six-year study to explore epistemic injustices in healthcare, which occur when patients' testimonies and perspectives are ignored or dismissed. The project aims to find ways to correct these injustices and improve the relationship between patients and healthcare practitioners.
A new surgical therapy has proven effective in treating melanoma in the eye that has spread to the liver, with 40% of patients experiencing tumor shrinkage, and offers a promising alternative to current treatments.
A recent survey experiment by Regina Bateson reveals that people with pandemic employment gaps are perceived more negatively than those who remained employed. This stigma could have long-term social and economic consequences for individuals who lost their jobs during the pandemic.
A new study found that girls born to obese mothers are at higher risk of developing obesity or overweight, with similar BMI and fat mass to their mothers. The association was not seen in boys or daughters from non-obese fathers.
A recent study found that graduate engineering identity and advisor-peer relationships play a crucial role in predicting degree completion intention. The research, conducted across 98 universities, reveals that strengthening these connections can lead to increased retention rates and improved support for neurodivergent students.
Researchers have discovered a novel medication that effectively treats a rare hereditary muscle disease causing complete immobility and death. The treatment has also shown promise in treating severe statin-associated myopathy, with improved symptoms in patients awaiting treatment.
A new study published in the European Heart Journal shows that using waist-to-height ratio instead of BMI provides a clearer picture of patient outcomes in heart failure. The researchers found that greater adiposity is associated with worse outcomes, including high rates of hospitalization and reduced health-related quality of life.
Researchers found that hematopoietic stem cells use aggrephagy to collect and destroy misfolded proteins, a process that is critical for maintaining stem cell fitness and longevity. Boosting this pathway could help preserve stem cell health and mitigate blood and immune disorders.
Researchers found that women with multiple sclerosis were more likely to report sleep disorders, including obstructive sleep apnea, insomnia, and sleepiness. Insomnia mediated more than 10% of the cognitive problems reported by women with MS, while sleep apnea accounted for 34%.
Scientists have calculated that the Amundsen Sea Embayment in West Antarctica has lost over 3,000 billion tonnes of ice over a 25-year period. The ice loss is attributed to extreme snowfall events and changes in ocean temperature and currents, contributing up to nine millimetres to global sea levels.
Scientists studied how the marsupial sabertooth's wide-set eyes and large canines affected its vision, finding that it could achieve about 70% visual field overlap through morphological compensation. This allowed it to be a successful active predator despite having orbits not favorably positioned for 3D vision.
Researchers found that physical activity can prevent cancer recurrence in stage III colon cancer patients by lowering the recurrence rate within the first year of treatment. This association persisted for approximately three years after surgery, suggesting a long-term survival benefit.
A new study found that exotic pet owners are concerned about species conservation and prefer captive-bred exotic pets. The survey of over 300 keepers across 33 countries revealed that relational motivations, such as caring about the species, outweighed aesthetic or morphological traits.
A novel lensless radiomicroscope has been developed for nuclear medicine imaging, offering high-resolution images of cells with a field of view over 500 times larger than current technology. The instrument is made from off-the-shelf parts and costs less than $100, making it accessible to more labs.
Alpha-gal syndrome is an allergy caused by lone star tick bites, leading to symptoms like stomach pain, diarrhea, and nausea. Patients with suspected alpha-gal should undergo a blood test to check for immunoglobulin E antibodies, and the main treatment is avoiding foods containing alpha-gal.
Researchers at ct.qmat created ferromagnetic topological insulator MnBi6Te10 with stronger magnetic field than its antiferromagnetic predecessor. The material's surface exhibits ferromagnetic properties, enabling lossless current conduction.