A new study from Karolinska Institutet found that biological drugs used to treat severe asthma do not completely eradicate inflammatory cells. Researchers discovered an increase in blood levels of these cells during treatment, which could explain why inflammation often returns when treatment is tapered or discontinued. The study aims t...
A new recycling technology has been developed to turn used tires into raw materials for rubber and nylon, achieving high selectivity of up to 92% and a yield of 82%. The process uses dual catalysis to convert waste rubber into valuable chemicals.
The SEB Conference 2025 will feature over 500 talks on latest advances in experimental research across animal, plant and cell biology. The event highlights groundbreaking research in biomechanics, wildlife conservation, human disease and bio-inspired robotics.
A USC-developed shipboard system using limestone and seawater can remove up to half of carbon dioxide emitted from shipping vessels, cutting maritime CO2 emissions by 50%. The process mimics a natural chemical reaction in the ocean, where CO2 is absorbed into water pumped onboard and then neutralized through a bed of limestone.
Astronomers have detected a vast cloud of energetic particles surrounding one of the most distant galaxy clusters ever observed. This discovery reveals that entire galaxy clusters were immersed in high-energy particles for most of their existence.
A recent study published in JAMA Network Open found significant associations between social factors like financial hardship, housing and food insecurity, and unsafe firearm storage practices. The researchers suggest that community-based education and support are key to understanding the behaviors driving gun ownership.
Researchers developed a solid-state NMR method to characterize separation and recycling processes of real-life plastic waste mixtures. The technique identified individual components in complex polymer systems, enabling precise tracking of chemical evolution and mapping of conversion processes.
Advanced computer simulations reveal shear deformations and internal mechanical stresses play a crucial role in grain growth and evolution. This discovery helps explain why real polycrystals behave differently than predicted and offers insights into designing stronger materials.
Researchers discovered two distinct ways mutation of the FOXA1 gene alters tumor formation and therapy resistance in prostate cancer in mouse models. The findings provide insight into how different classes of FOXA1 mutations operate, shedding light on the complex mechanisms driving prostate cancer progression.
Researchers developed a novel CrTe2/NbSe2 heterostructure to create stable, controllable interfaces between magnetic and superconducting materials. The structure forms stripe-like patterns hosting localized magnetic moments, enabling topological quantum computing applications.
A study reveals how HIF-1α adapts cells to different levels of oxygen deprivation by activating specific genes, including those involved in glycolysis, immune suppression and angiogenesis. The research provides a framework for understanding hypoxia-induced cellular responses and identifying precision targets for therapeutic strategies.
Scientists have developed a method to produce macrocyclic peptides using brewer's yeast, which can be rapidly analyzed for therapeutic applications. The approach harnesses the natural machinery of yeast to create biocompatible and biodegradable peptide molecules with precision targeting and stability.
NRG Oncology has appointed Tambre Leighn as Chair of the Patient Advocate Committee and Chris Holsinger as Surgical Vice Chair of the Head and Neck Cancer Committee. These new leaders will focus on advancing patient advocate engagement and expanding NRG's head and neck cancer portfolio.
A recent study published in Stem Cell Reports found that microgravity accelerates skeletal muscle degeneration, leading to a decline in muscle strength and protein content. The researchers used an ISS lab-on-chip model to simulate ageing-related muscle loss and discovered that electrical stimulation can mitigate these changes.
A new study suggests current return-to-play protocols for community sport athletes may not be enough to ensure player safety following a concussion. Researchers recommend symptom-based assessments and personalized rehabilitation plans to support recovery and reduce the risk of reinjury.
Researchers discovered lower α-synuclein levels in red blood cells of patients with Dementia with Lewy Bodies, a potential biomarker for early diagnosis. This finding may contribute to improving treatment outcomes and patient care for those affected by DLB.
Researchers at the University of Oklahoma investigate the overlap between cognitive decline caused by chemotherapy and aging, discovering decreased blood flow, disrupted blood-brain barriers, and senescent cells. Removing these cells with senolytics can improve cerebral blood flow, cognition, and overall brain health.
Researchers used advanced neuroimaging and the Julich-Brain Atlas to identify specific brain networks linked to psychopathy, finding reduced volumes in multiple regions including basal ganglia, thalamus, and cortex. This study advances research on neuropsychobiological correlates of aggression.
Research reveals that KNL2 degradation is critical for centromere integrity and mitotic fidelity. The study found that alpha-KNL2 in Arabidopsis thaliana is degraded during mitosis through ubiquitin-dependent proteolysis, highlighting the importance of tight protein regulation during cell division.
Researchers found several volatile phases in the polar jet stream over the past 125 years that predate significant climate change effects. The study suggests that natural fluctuations may be driving recent erratic behavior of the jet stream, rather than climate change.
A new study from the University of Bath found that individuals with a higher IQ make more realistic predictions, leading to improved life outcomes. Smarter people are significantly better at forecasting, making fewer errors and showing more consistent judgement compared to those with a lower IQ.
The latest issue of Optica Quantum features research on cryogenic photonic links for superconducting qubits, spatio-spectral quantum state estimation of photon pairs from optical fiber, and quantum optical reservoir computing powered by boson sampling. These studies demonstrate breakthroughs in measuring and optimizing quantum states, ...
A team of Korean researchers has successfully recreated a golden fiber akin to that of 2,000 years ago using the pen shell cultivated in Korean coastal waters. The breakthrough reveals the scientific basis behind its unchanging golden color and demonstrates the potential of eco-friendly materials.
Research by Christian Schubert and Scott Lafontaine reveals rice's brewing benefits, including improved flavor profiles and shorter fermentation times. The study highlights the potential of rice to enhance nonalcoholic beer quality, offering a sustainable alternative to traditional brewing methods.
A study has discovered a connection between ferroptosis, a type of iron-dependent cell death, and inflammatory bowel disease. Lipid ROS activate ferroptosis, which drives cell death in the colon lining, and inhibiting this process may lead to new treatment options for IBD.
Researchers analyzed genomic data from over 2,700 Indians to reconstruct evolutionary history, revealing ancestry tied to Neolithic Iranian farmers, Eurasian Steppe pastoralists, and South Asian hunter-gatherers. The study highlights the impact of ancient migrations on genetic variation and disease susceptibility.
The study found that significant changes in sleep metrics occurred only when inflammation was present in the body, with symptoms alone not resulting in any notable sleep disruption. Sleep disturbances worsened leading up to inflammatory flares and improved afterward, suggesting that sleep changes may signal upcoming disease activity.
Academic medical centers can transform patient care by adopting learning health system principles, harnessing real-time data analysis and AI to improve patient outcomes. The proposed model aims to establish a smarter, more efficient and equitable care model by integrating diverse databases and leveraging AI for personalized, proactive ...
Researchers from SNU developed a groundbreaking hardware security technology based on commercially available V-NAND flash memory, enabling secure generation, storage, and concealment of keys. The Concealable PUF technology maintains unclonability and randomness while adding the ability to hide and reveal the security key as needed.
A nanometer-thin spacer layer has been inserted into exciplex upconversion OLEDs (ExUC-OLEDs) to improve energy transfer, enhancing blue light emission by 77-fold. This design enables the use of previously incompatible materials, paving the way for lightweight, low-voltage, and more flexible OLEDs.
Researchers studied the effects of 6-PPDQ on the citric acid cycle in C. elegans, finding disruptions at environmentally relevant concentrations. The study revealed reductions in key metabolites and enzyme gene expressions, contributing to mitochondrial dysfunction and toxicity.
PTEN-deficient mouse models exhibit ASD-like characteristics due to circuit imbalance and altered behavior. The study reveals specific circuit changes in the amygdala resulting from PTEN loss in inhibitory neurons, providing new insights into the underlying circuit alterations that contribute to heightened fear and anxiety.
A new study from UC San Diego reveals that even mild heat can significantly hinder team performance, while leaving individual productivity unaffected. Teams in warmer conditions experienced a notable decline in productivity due to communication and interaction breakdowns.
The Nature Relationship Index (NRI) aims to measure a country's sustainable path by assessing its relationships with nature, tracking progress and development. The NRI adds an environmental dimension to the Human Development Index, fostering mutually beneficial relationships between humans and the natural world.
Increased public awareness of solar geoengineering may lead to bipartisan engagement in US politics. The study found that Americans' views on the technology became more moderate as they gained knowledge about its effects and mechanisms.
A new study published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging found that individuals with remitted depression show increased habenula activity and reduced connectivity between the habenula and dopamine-producing regions, suggesting a heightened sensitivity to negative cues. This suggests that even after recove...
The BONSAI Climate Footprint Analyser helps users understand the climate impact of various products and materials through a free, publicly accessible platform. The tool provides accurate CO₂e values for over 1,000 products across 40 countries, enabling organisations to assess and reduce their climate footprint.
FANDANGO, a new open-source fuzzing tool, employs an iterative procedure modeled on biological evolution to produce high-quality test inputs that cover both semantics and syntax. The tool enables complete control over test inputs, allowing testers to specify input characteristics and explore specific parts of the program.
Researchers found that 2.7% of 70-year-old women had meningiomas, a type of tumor on the meninges outside the brain tissue. The study emphasizes the importance of diligence and careful consideration in managing these tumors, which are often benign and grow slowly.
This issue of SLAS Technology features a high-precision microfluidic flow splitter that outperforms commercial alternatives, enabling even flow division and simplifying multi-inlet perfusion. The journal showcases technological leaps in the life sciences, including rapid pathogen detection and AI-driven insights into schizophrenia.
Researchers detected a slow slip earthquake in Japan's Nankai Fault, behaving like a tectonic shock absorber. The event revealed fluids are a key ingredient for slow earthquakes and confirmed that the fault releases pent-up energy harmlessly.
Researchers found increased activity in two brain areas when participants reported cognitive fatigue: the right insula and dorsal lateral prefrontal cortex. These areas work together to regulate mental effort, suggesting that external incentives can prompt increased cognitive effort.
A new study by Boston University's Richard A. Currie explores the impact of workplace nosiness on employee performance and satisfaction. Researchers found that employees react to nosiness by pulling down their privacy boundaries, leading to higher stress levels and lower task performance.
Researchers Brian Yanites and colleagues propose a unified, interdisciplinary approach to studying cascading land surface hazards. The new framework aims to refine theory, models, and hazard monitoring to better understand and manage interconnected threats.
Researchers used magnetoencephalography (MEG) technology to determine how levodopa affects brain signals in patients with Parkinson's disease. The study found that some patients experience 'off-target' effects of the drug, affecting brain regions beyond the intended dopamine-replacement therapy area.
Access to buprenorphine and naltrexone for opioid use disorder is affected by race and ethnicity, as well as insurance type. Targeted interventions, including culturally tailored care and expanded access points, are needed to address disparities and reduce inequities contributing to the overdose crisis.
Researchers at the University of Córdoba develop a biodegradable emulsifier from avocado pruning residue, improving stability and shelf life of emulsions. The new emulsifier also exhibits enhanced antimicrobial and antioxidant activity, making it a promising alternative to petrochemical-based emulsifiers.
Researchers have characterised the human protease SENP5, implicated in various diseases such as cancer and neurodegenerative disorders. The study reveals a positively charged region that prefers SUMO2 binding, opening the way for specific inhibitor design with minimal side effects.
A global coalition of experts released the Copenhagen Declaration, a framework to revolutionize diabetes care and research globally. The declaration outlines four urgent strategies to close gaps in treatment and innovation, with a focus on low- and middle-income countries.
Researchers identified hundreds of molecular markers in saliva associated with systemic pathological processes beyond the oral cavity. These markers can reflect genetic heritability of diseases such as prostate cancer, coronary disease, and Type 2 diabetes.
A Kobe University team developed a technique to classify thousands of enzymes, allowing for rapid evaluation and identification of highly active and versatile enzymes. The approach enabled the discovery of an enzyme with up to 10 times higher productivity than industry standards.
A new study suggests tailoring TB treatment to disease severity could improve patient outcomes and prevent the spread of drug-resistant strains. By identifying patients with less severe forms of TB, treatment courses can be safely shortened, reducing the risk of treatment failure and relapse.
A new approach enables hospital pharmacists to rapidly create bespoke medicine cartridges for rare disease patients, boosting access to personalized treatment. The NANOSPRESSO platform could open up treatments for underfunded and underserved rare conditions worldwide.
A study reveals that ultra-small nanoparticles can induce abnormal protein conformation and have the potential to cause pathological conditions like Alzheimer's disease. The researchers used spectroscopy-based experiments to analyze the interactions between bovine serum albumin and silica nanoparticles.
More than 1 million people worldwide are diagnosed with bronchiectasis, a chronic lung disease characterized by enlarged airways. Global partners unite for World Bronchiectasis Day to share resources on self-management, mental health, and nutrition to improve care and quality of life for those affected.
The new centre will investigate neural dynamics, developing novel interventions and devices to improve symptom relief and quality of life for people with brain disorders. It aims to harness neural dynamics for people with conditions like Parkinson’s disease or epilepsy.
Veterans with female sex and racial/ethnic minority groups are disproportionately affected by opioid overdose deaths. Younger females and racially minoritized veterans experience high rates of overdose deaths during times of healthcare stress.
The American Society for Radiation Oncology (ASTRO) has updated its guideline on radiation therapy for high-grade diffuse gliomas, the most common primary brain tumor in adults. The new guideline provides evidence-based recommendations for multidisciplinary treatment and addresses optimal radiation dosing, fractionation, and techniques.
A new study found that runners who focus on a single point ahead of them, such as the finish line, can increase their effort and performance. This mental strategy, known as attentional narrowing, was associated with faster running times and higher heart rates.
Most opioid treatment programs still do not offer all three forms of medication-assisted treatment (MAT) as of 2023. Government-operated programs and those accepting Medicare are more likely to provide comprehensive MAT offerings.