The Lasker Foundation has announced the 2025 Lasker Award winners, recognizing Dirk Görlich and Steven L. McKnight for their discovery of low-complexity domains within protein sequences. Michael J. Welsh, Jesús González, and Paul A. Negulescu have also been honored for developing a novel triple-drug combination therapy for cystic fibro...
A new analysis reveals African women remain significantly underrepresented in water governance, with only 17% of national ministries led by women. Practical steps are needed to address social and institutional barriers and ensure women's equal representation in shaping policies and decisions.
Ochsner Health has been recognized as one of the best companies to work for in the U.S. by Fortune Media and Great Place to Work, based on analysis of survey responses from nearly 228,000 employees. The recognition reflects Ochsner's commitment to supporting its team members' full potential.
A study by Okinawa Institute of Science and Technology researchers found that 79% of endemic ant species in Fiji are declining over the past few hundred years, coinciding with European contact and modern agricultural techniques. In contrast, non-native ant species are exploding in population.
A research team from HKUST developed a novel AI-powered tool named STIMP for diagnosing coastal ocean productivity and ecosystem health. The tool significantly outperformed existing geoscience tools in tests across four global coastal regions.
Ginseng exhibits multifaceted benefits through its immunomodulatory properties, improving quality of life by alleviating chronic fatigue and cognitive decline. Its extracts also show promise in inhibiting tumor growth and metastasis, suggesting potential as an adjunct therapy in oncology.
A Norwegian researcher has identified key factors contributing to recidivism after imprisonment, including mental health, relationships, motivation, and support systems. The study found that 'soft' factors are equally important as 'hard' variables in predicting reoffending risk.
Researchers at Ohio State University are developing a new nuclear thermal propulsion system, called the centrifugal nuclear thermal rocket (CNTR), which could potentially double an engine's efficiency. The CNTR concept aims to improve rocket performance while minimizing risk and enabling faster travel times to distant destinations.
Lucy Shapiro, a pioneering biologist and advocate, is awarded the Lasker-Koshland Award for her life-changing trajectory in chemistry and biology. Her work on bacterial compartmentalization has overturned prevailing ideas and paved the way for new discoveries.
Researchers are analyzing leaf and soil samples from diverse areas to determine beneficial or harmful roles of different microbes. The study aims to improve crop production practices and overall yield by assessing the health of soil rhizosphere.
A study by the University of Oulu found that adolescent ADHD symptoms affect adult income indirectly, through education and other psychiatric disorders. The study revealed a 25% decrease in incomes among individuals with both ADHD and ODD, highlighting the importance of preventive services and investments in education and mental health.
A study by SeoulTech researchers found high levels of polycyclic aromatic hydrocarbons (PAHs) in common food items, including cooking oils and meats. The QuEChERS-GC-MS method revealed carcinogenic compounds with limits of detection ranging from 0.006 to 0.035 µg/kg.
The Society for the Advancement of Material and Process Engineering has awarded Oak Ridge National Laboratory the 2025 SAMPE Organizational Excellence Award. The award recognizes ORNL's extraordinary contributions to advanced materials and processes, enabling breakthroughs in industries such as aerospace and automotive.
ThriveLink has been selected as the winner of the inaugural Kraft Prize, a $100,000 national prize dedicated to transforming health outcomes in communities. The organization's telephonic AI enrollment solution empowers families to verbally complete and submit applications for safety-net programs.
A recent article argues traditional educational research has reached a breaking point and must be reimagined in the age of artificial intelligence. The authors identify long-standing problems with educational research and outline a vision for its rebirth in an AI-driven world.
A significant increase in Pap smear avoidance was observed among US women following the COVID-19 pandemic, with 26% of women going without screening in 2022 compared to 19% in 2019. This trend was particularly pronounced among African American women, highlighting the need for targeted health interventions.
Ves-GAN, an unsupervised vessel-targeted denoising framework, significantly improves LDCTA imaging by minimizing noise while preserving intricate vascular structures. This innovation enhances diagnostic accuracy in cardiovascular disease diagnosis, directly impacting patient outcomes.
The International Classification of Diseases (ICD) is now assigning a dedicated diagnostic code to Gulf War illness, recognizing the condition's chronic nature and physical symptoms. This development aims to improve diagnosis, treatment, and research for veterans affected by the Gulf War.
A recent study reveals that circFKBP8(5S,6) or cFKBP8 promote susceptibility to chronic unpredictable mild stress in mice by down-regulating DRD3 expression and disrupting AMPK/mTOR/ULK1 autophagy signaling. Behavioral studies demonstrate exacerbated depressive-like phenotypes, which can be mitigated by the DRD3 agonist cariprazine.
Research reveals that municipalities near healthy forests face lower risk from cardiovascular and respiratory diseases. The study, led by the International Union for Conservation of Nature, found that Indigenous forests bring health benefits to millions and can prevent millions of cases of respiratory and cardiovascular infections each...
Researchers cataloged octopus arm movements in six different locations, revealing diverse behaviors such as foraging and locomotion. The study provides insights into the complex motions of octopus arms, which are guided by sensory organs and can perform a variety of tasks, including manipulating objects.
Researchers have identified a key immunoregulatory mechanism in aspergillosis, where the dendritic cell receptor limits the host's response to fungal infections. Neutrophils play a crucial role in clearing fungal hyphae, and Dcir regulates their degranulation activity, which is essential for killing pathogens.
A recent study developed three distinct caregiver personas: Checklist Cheryl, Social Sam, and Responsive Rhonda. These personas embody different approaches to medication management, varying in organization, technology use, collaboration, and response to challenges. The study found that caregivers employ diverse strategies blending tech...
A four-year NIH grant will support a study of type 1 diabetes, led by Dr. Shuibing Chen at Weill Cornell Medicine. The researchers will investigate the interplay between genetic and environmental triggers using advanced laboratory and computational tools.
A new genetic test developed at Mayo Clinic is redefining how clinicians diagnose and manage hereditary pancreatitis. The test includes nine genes and uses whole exome sequencing to analyze coding regions, providing comprehensive analysis of disease-causing genes.
A recent sale of genetic data by 23andMe highlights critical gaps in legal protection for genetic information in the US. The authors argue that stronger safeguards are needed to protect consumers from potential misuse and exploitation of their genetic data.
A new evidence-based plan tackles anaemia, a major obstacle to global health goals. The study recommends cost-effective strategies and calls for better data systems to track anaemia and its causes.
A new study published in Clinical Chemistry and Laboratory Medicine has developed a practical tool to support harmonization and quality improvement in vitamin D testing. The multicentre study evaluates the measurement uncertainty of various 25-(OH)D assays and their ability to detect physiologically relevant changes over time.
The study found that buprenorphine produced the greatest health gains and cost savings for mothers and infants compared to alternative treatments. Buprenorphine was shown to be protective against critical outcomes such as preterm birth and low birth weight, despite its association with neonatal opioid withdrawal syndrome.
A recent study using transits and light curves revealed that TOI-3884 is a highly tilted planetary system with a misaligned stellar spin axis and planet's orbital axis. The star's rotation period was also measured, providing insight into the system's unique geometry.
Researchers have developed a high-performance mid-infrared imaging system without lenses, capturing clear pictures over large distances and in low light. The system uses an optical pinhole inside a nonlinear crystal to form an image, which is then converted into visible light, allowing for distortion-free and large-depth imaging.
A new nanostructure acts like a wire and switch that can control the flow of quantum quasiparticles called excitons at room temperature. The transistor-like switch developed by University of Michigan engineers could speed up information transfer or enable circuits that run on excitons instead of electricity.
Researchers at UMass Amherst found that certain T-cells have an inherent ability to remember past viral foes, which could lead to next-generation cancer vaccines. This 'immunological memory' is crucial for the body's immune response and can be harnessed for targeted therapies.
American Indian and Alaska Native residents in Oklahoma face significant cancer disparities due to barriers in accessing lifesaving cancer care. A new care coordination and communication program aims to address these challenges by facilitating virtual huddles between healthcare teams.
A study by Aarhus University researchers has identified a defect in the production of exosomes in cells as being associated with mutations seen in dementia patients. This defect may lead to a better understanding and potential treatment for Alzheimer's disease.
This study introduces ViFT, an AI framework that accelerates and stabilizes visual field testing. By leveraging transformer structures and simulated patient responses, ViFT achieves higher accuracy than state-of-the-art strategies with reduced test time.
A new study finds that wildfires in the western US worsen local air quality but unexpectedly improve air quality in the eastern US due to heat's effect on weather patterns. This overlooked factor significantly alters regional air quality, with climate models overestimating pollution impacts.
A European consortium presents an innovative mission concept to explore the moon's hidden caves using three heterogeneous robots that collaborate autonomously. The mission aims to map and collect data in extreme environments, with promising applications for future lunar or Mars missions.
Paleontologists have identified a new species of dinosaur from Triassic fossil beds in South Wales, using modern digital scanning techniques. The fossil jawbone was correctly identified after being on display for over 125 years.
Record cattle prices and large government payments are expected to boost US farm income to $177 billion in 2025. However, crop price declines and reduced future support raise concerns about a potential $31 billion decline in farm income next year.
A recent study identifies C1orf122 as a novel biomarker for hepatocellular carcinoma (HCC) progression and prognosis. C1orf122 promotes HCC via the SRPK1-PI3K/AKT/GSK3β axis, enhancing cell proliferation, suppressing apoptosis, and facilitating cell migration.
Researchers discovered elevated TSPO levels in the brain of genetically engineered mouse models and human patients with familial Alzheimer's disease, indicating a potential biomarker for early detection. The study aims to explore how blocking or enhancing TSPO could halt disease progression.
Researchers have identified a risk category called 'pre-prediabetes' that occurs years before standard criteria for prediabetes are met. This stage is characterized by severe insulin resistance and measurable cardiovascular disease, highlighting the need for early detection and treatment.
Researchers investigated tirzepatide's therapeutic efficacy on MASLD, a complex liver disease characterized by abnormal lipid accumulation and inflammation. Tirzepatide alleviated hepatic steatosis in mouse models by enhancing lipolysis and reducing lipid uptake through the regulation of CD36 and OBP2A.
A new study finds that most native Fijian ant species have declined since humans first arrived 3,000 years ago, while introduced species have expanded. Human activities such as habitat destruction and agricultural intensification are shaping fragile island ecosystems.
A new study suggests that volcanic activity on early Mars emitted sulfur gases, creating a greenhouse effect and making the planet's climate more hospitable to life. The research found high concentrations of chemically reduced forms of sulfur, which are highly reactive and could have induced a hazy environment.
A study led by Danish researchers highlights the rapid spread of invasive plant species in tropical regions, altering food chains and damaging traditional ecosystem services. The phenomenon is exacerbated by climate change, leading to widespread ecosystem collapse and degradation.
Researchers at Hiroshima University have developed a highly sensitive method to detect the Unruh effect, which is a prediction at the intersection of relativity and quantum theory. The approach utilizes circular motion of metastable fluxon-antifluxon pairs in coupled annular Josephson junctions.
A prospective study of the Adolescent Brain Cognitive Development cohort found that modifiable parental factors, such as screen use and emotional regulation, are associated with specific adolescent sleep outcomes. Parental warmth is also linked to sleep chronotype, highlighting potential targets for evidence-based interventions.
Researchers have demonstrated a portable, noninvasive technology that can detect metabolic changes linked to Alzheimer's disease by measuring cytochrome c oxidase activity. The study found that including oxCCO measures improved the ability of the brain-monitoring tool to capture clinically relevant brain changes.
A sophisticated neutron flux diagnostic system will gather knowledge of plasma and power released in nuclear reactions at ITER. The High Resolution Neutron Spectrometer (HRNS) measures both neutron number and energies, providing information on fuel composition, ion temperature, and combustion quality.
Researchers found a significant association between financial toxicity and worse emotional and physical well-being among cancer patients. Financial toxicity, which includes stress, expense, and instability caused by healthcare costs, can have far-reaching consequences, including psychological distress and lower quality of life.
A study reveals how PGC-1α protein and estrogen work together to boost thermogenesis in females, outperforming males. This finding highlights a sex-specific mechanism of energy metabolism and suggests new therapeutic targets for obesity and diabetes prevention.
Boston University researcher Nobuyuki Ishibashi has been awarded a $6.5M grant from the Department of Defense to study caspase inhibition for neuroprotection in pediatric cardiac surgery patients who suffer from life-long neurological deficits and behavioral problems.
Researchers investigate the role of mast cells in eosinophilic esophagitis, a chronic disease causing inflammation and scarring. The study aims to identify new treatments to improve quality of life for patients with EoE.
A new study finds that women who have overcome cervical cancer are nearly twice as likely to develop anal cancer compared to the general population. The study highlights the need for updated screening guidelines for these patients.
Researchers studying age-related cognitive decline may discover a novel therapy using extracellular vesicles from young stem cells. The treatment aims to slow memory loss with aging and potentially protect against Alzheimer's disease.
Scientists at King's College London discover mathematical equations that turn random events into clocks, potentially understanding cell timekeeping and detecting quantum effects. The study also aims to shed light on the nature of time itself, including its directionality and quantization.
A new study found that individuals with lower life satisfaction and daily challenges were more likely to use digital well-being apps, but app engagement was highest among those with higher life satisfaction. The study identified three user archetypes: thriving nonactive users, struggling nonactive users, and active users.
Researchers at Yale University have measured the movement of protons through electrically charged water on a microscopic scale for the first time. The study provides well-defined parameters for chemical simulations, which can inform theorists about water-mediated proton transfer.