A new study suggests that data centers can lower average energy costs by providing grid flexibility during high-cost periods. The researchers found cost savings of up to 5% in Texas, 4% in the Mid-Atlantic region, and 2% in western U.S. states by shifting more than 20% of their consumption to non-peak hours.
Researchers identified a previously unrecognized immune system pathway that connects cigarette smoking to cardiovascular disease. Cigarette smoke activates immune cells, triggering widespread inflammation throughout the body and accelerating plaque buildup in arteries.
A new study by Texas A&M University researchers uses a non-toxic virus to induce Parkinson's-like brain damage and movement problems in animal models. The breakthrough model confirms that viral infections can trigger Parkinson's disease, paving the way for future studies on early warning signs and biological markers.
A recent study found that moderate soil moisture enhances nitrification under higher ammonium supply, while waterlogged conditions suppress aerobic nitrifiers due to limited oxygen. The researchers observed a mismatch between microbial activities, leading to nitrite accumulation.
New research shows that young salmon are more susceptible to heat stress than older fish, and current methods may be underestimating the risks. Younger fish can tolerate warmer temperatures for longer periods, but fish acclimated to cooler temperatures struggle with rapid heat events.
A digital financial-incentives intervention provides rewards for verified smoking abstinence, supporting the effectiveness of a smartphone-based treatment. The treatment aims to bypass limitations in rural communities and deliver life-saving support directly to families who need it most.
Researchers discovered graphene can host multiple superconducting states, some persisting even in the presence of strong magnetic fields. The team found that certain experimental conditions could control the material's properties, leading to a new family of unconventional superconducting states.
A new study published in JAMA Network Open has found an association between cardiovascular disease risk factors and visual impairment in Hispanic/Latino adults. The research suggests that individuals with three or more risk factors, such as diabetes, high cholesterol, and hypertension, are more likely to experience visual impairment.
A new estimate of insect species globally suggests that there may be 8-14 million more species than previously thought, with many yet to be discovered. The study, using genetic information and statistical strategies, conservatively estimates the total number of insect species at around 14-20 million.
Scripps Research scientists captured high-resolution structural images of human Argonaute 2 in its cutting-ready state, identifying precise atomic interactions that determine when and where the machinery cuts. The structures reveal key amino acids driving the cutting reaction, including Lysine709 and Arginine710.
Researchers found evidence of early ozone loss dating back to the late 1950s, linked to carbon tetrachloride use, in contrast to CFCs' later role. This discovery reveals that modern monitoring tools could have detected earlier signs of human-induced depletion.
Researchers at Australian National University trained people to detect AI-generated faces using global qualities such as symmetry and attractiveness. The ability to spot AI faces improved significantly, with high performers achieving near perfection.
A global study reveals that culture influences how people try to regulate the emotions of others, with individualistic cultures prioritizing comforting and expressing care, while collectivistic cultures often view unpleasant emotions as valuable. This finding highlights the importance of cultural context in emotional support.
Researchers have identified an alternative path for membrane protein insertion in bacterial cells, contradicting previous assumptions. This finding sheds light on the folding processes of membrane proteins and their evolutionary development.
A new analysis of state health department data reveals that more than 6,400 Illinois residents were diagnosed with tickborne diseases from 2004-2022. Lyme disease is the most common tickborne malady in humans in the state, accounting for 4,297 infections.
A new study from Boston Medical Center found that a group mindfulness program can effectively treat chronic low back pain. Participants showed significant improvements to pain and daily functioning after the program, with gains sustained at a 12-month follow-up.
Research suggests that an anti-inflammatory molecule, IL-6, plays a role in driving excessive drinking behavior in alcohol use disorder. Blocking IL-6 reduced alcohol consumption in female mice, but not male mice or non-dependent animals. The study adds to growing evidence of brain inflammation's involvement in alcohol use disorder.
Scientists at Scripps Research have found that disabling a specific bacterial enzyme called SagA can restore the effect of vancomycin against resistant bacteria, making them treatable without needing a new antibiotic. This approach targets basic aspects of bacterial physiology and could overcome antibiotic resistance.
A new study reveals ATOX1 as a key regulator of oxidative stress, neuroinflammation, and microglial survival in Alzheimer's disease. ATOX1 expression is downregulated in microglia associated with Aβ plaques, leading to copper accumulation and cellular toxicity.
Researchers are conducting a large online study to better understand how people make decisions about short-term versus long-term rewards. The study, which involves over 15,000 participants from 77 countries, aims to uncover the factors that influence intertemporal choices and their effects on daily life.
Researchers found PLXNC1 expression is significantly upregulated in CMS4 tumors, serving as an independent risk factor for poor overall survival. Elevated PLXNC1 promotes mesenchymal phenotype, stromal infiltration, and immunosuppressive tumor microenvironment.
Lipid molecular geometry controls membrane stretching elasticity, while three-dimensional DNA networks govern bending resistance. Researchers developed a framework to dissect the mechanics of artificial cells, revealing a clear division of labor at the molecular level.
A new international study reveals that evolutionary success is not fixed and follows no rules when environmental conditions change. Using corals as an example, researchers demonstrated that even seemingly successful life strategies can lose their advantage when environmental conditions shift.
Ionic thermoelectric materials have been found to tap into low-grade waste heat with unusually high thermopowers, enabling applications such as wearable patches, smart buildings, and energy-harvesting smart windows. Challenges in standardization, scalability, and sustainability hinder commercialization.
The ANERIS project successfully demonstrated cutting-edge technologies for marine life sensing and monitoring, focusing on Operational Marine Biology (OMB) products. Key findings include the deployment of four case studies connected to Research Infrastructures, showcasing high-temporal marine life resolution monitoring.
Researchers observed a 'buckling' behavior in viral capsids as they transitioned from hydrated to dehydrated states. The changes occurred locally, with some regions adapting before others, challenging a common assumption about viruses being rigid containers.
A study of three Canadian cities found that children and older adults are less likely to live near bike lanes. Montreal made significant progress in closing the gap, while Vancouver and Victoria had more concentrated expansions in downtown areas.
Recent research suggests that senescence often limits stem cell activity in normal tissues but can also promote tumor progression in cancer. Understanding the dynamic interplay between these two biological processes is crucial for developing safer regenerative therapies and more effective cancer treatments.
A novel dynamic modeling approach for a net-membrane capture system accounts for combined deformations, enabling effective capture of stationary and spinning debris. The study identifies optimal shooting parameters, demonstrating excellent despinning capability during capture.
A nanosensor developed to study cardiovascular disease successfully distinguishes autism spectrum disorder (ASD) from intellectual disability (ID), even when both conditions share the same genetic mutation. This method measures real-time nitric oxide production in patient-derived stem cells, offering a new diagnostic pathway for ASD.
Researchers discover that kidney cancer cells lacking the tumor suppressor gene SETD2 become highly dependent on protein BCL-xL for survival. By targeting this dependency, they can selectively eliminate SETD2-deficient cancer cells, offering a potential new therapeutic strategy for patients with aggressive subset of kidney cancers.
A new study reveals that Neanderthals and modern humans shared strikingly similar growth processes during the later stages of pregnancy. The researchers used high-resolution micro computer tomography to analyze fossils from three young Neanderthals, which showed a remarkable similarity in skeletal development before birth.
Scientists discovered a protein secreted by deep-sea extremophile Pyrodictium abyssi that self-assembles into a highly stable biofilm. This discovery opens new avenues for biomedical research and could lead to breakthroughs in wound dressing, medical device coatings, and tissue engineering.
Researchers engineered HER2-specific CAR-T cells to simultaneously silence TIM-3 expression, demonstrating improved anti-tumor responses and significantly elevated lytic cytotoxicity. In vivo evaluations showed delayed tumor growth and minimized tumor burden with this strategy.
Researchers used a brain vital signs framework to monitor cognitive and neurophysiological function in astronauts on a 17-day mission. The results showed minimal differences in accuracy and reaction time across various cognitive tasks, with no significant neurophysiological decline.
The Building Envelope Alliance brings together research institutions, universities, and innovation accelerators to provide integrated access to consulting services, testing, and training. This network aims to simplify innovation tools for designers and industry professionals, bridging the gap between technological development and pract...
A new study from the University of Georgia suggests marigold flowers contain similar amounts of protein as quinoa, making them a potential plant-based protein source. The flower's proteins also exhibit unique properties, such as stability at high temperatures and umami flavor, which could make it ideal for baking and food formulation.
A study analyzing 287 people with MS found distinct patterns of brain damage and repair linked to disease severity. Genetic variants contributing to MS were associated with inflammation, immune cell activity, and myelin repair.
A new study reveals that excessive fibrin deposition drives chronic inflammation in diabetic periodontitis. A targeted peptide successfully stops this inflammation and promotes periodontal bone regeneration, offering a potential universal therapeutic strategy for various immune-mediated diabetic comorbidities.
The restitution follows several years of collaborative provenance research under the Benin Initiative Switzerland, which showed that the objects were most likely looted from the Kingdom of Benin during the British attack in 1897. The returned artefacts will be displayed at the National Museum in Lagos and temporarily stored in Edo State.
A mouse study found that social isolation during adolescence impairs emotion recognition and social behavior in adulthood. Resocializing does not reverse these behavioral changes. The study also showed that socially isolated adult mice were unable to tell the difference between stressed and unstressed mice.
Researchers at Rice University develop a new way to model the cochlea's sound processing using graph signal processing, identifying broader functional relationships between sensory cells. The model, called GSP Cochlea, performs better in detecting signals in noise and may hold the key to personalized device settings for hearing aids.
Researchers propose homeostasis-restoring strategies involving exogenous nitrate interventions and targeted stem cell regulation for diseases such as dental caries, periodontitis, cancer, cardiovascular and metabolic diseases. This new paradigm aims to prevent diseases before they arise.
A new study published in EMBO Molecular Medicine shows that anle138b can significantly reduce toxic protein clumps in the brain and alleviate symptoms of Huntington's disease. The compound also addresses the underlying cause of the disease by preventing disease-specific harmful protein aggregates.
The new photonic architecture harnesses three fundamental degrees of freedom: wavelength, mode, and polarization, achieving 192 parallel computing channels. The chip supports large, reconfigurable convolution kernels up to 13x13, capturing global structural contours while preserving fine details.
Researchers use unsupervised learning and neural networks to group anomalous Hall curves into distinct families, creating a roadmap for understanding complex magnetic behaviors. The framework predicts desirable properties and guides the search for rare quantum states.
Researchers proposed a novel method for detecting Earth's free oscillations utilizing TianQin, achieving high signal-to-noise ratio of 73 and distinguishing multiple modes. This method leverages frequency splitting effect to circumvent calibration errors, enabling precise probing of Earth's internal structure.
Researchers identify CD36 as a key regulator connecting circadian rhythm disturbances to abnormal bile acid metabolism and cholestatic liver injury. Elevated CD36 expression contributes to inflammatory activation and liver fibrosis, while CD36 deficiency restores bile acid metabolic rhythms and reduces liver damage.
The Insect Calculator web tool uses a formula based on twelve influencing factors to predict the number of insects per square meter. By comparing unmown and mowed meadows, researchers found that mowing reduces insect populations by up to 73%.
Researchers develop novel PROTACs to target molecular drivers of cancer, showing effectiveness against aggressive tumor cells and limited side effects. The new approach offers a promising strategy for treating treatment-resistant cancers and improving survival rates.
University of Michigan researchers developed a framework to help stakeholders consider economic, environmental, and social trade-offs in EV battery development. The framework aims to balance the needs of various stakeholders, including manufacturers, drivers, and recyclers, to achieve better outcomes for batteries and electric vehicles.
Researchers used eye-tracking technology to analyze how student nurses interact with intravenous smart pumps, identifying design flaws that lead to medication errors. The study found significant differences in usability and ease of use among four IV smart pumps, suggesting that interface design plays a critical role in user performance.
A new study from Ben-Gurion University of the Negev found that long-term Salmonella infections severely damage blood stem cells. However, researchers discovered that giving an effective course of antibiotics fully restores the stem cells' health and rebuilds their power.
This study proposes a frequency-sweeping interferometry technique to measure intertelescope baselines with high precision and stability. Experimental results demonstrate improved stability by 33.47% and ranging accuracy of 44.30 μm over 10 m range.
A new Cornell University study found that young adults who reflected on their life story and connected it to different stages reported reduced symptoms of depression. The intervention involves writing about motivations, passions, or goals at various life stages over two weeks, with participants summarizing their identity in a word.
A new five-year project at Wayne State University aims to investigate the effects of e-cigarette use during pregnancy on fetal brain development. The research will utilize a state-of-the-art vaping system to model real-world exposures and examine their effects on neurodevelopment.
Researchers found limited benefits to under-twos' screen time and a lack of guidance for parents, calling for targeted support and reduced screen time. The iADDICT group recommends no intentional screen time for under-twos to mitigate developmental concerns and promote healthier habits.
A new review reveals autophagy's complex role in neuropathic pain, with moderate protection in neurons and pro-inflammatory effects in astrocytes and microglia. Targeting autophagy may address both pain and its emotional comorbidities like anxiety and depression.
A patient-derived KDF1 mutation impairs enamel-forming cells by disrupting cell adhesion and Hippo-YAP signaling. Mutant mice exhibit thinner enamel, reduced mineral density, and delayed tooth eruption.
A new review article highlights the molecular mechanisms behind the anti-diabetic effects of 16 medicinal plants, including Gymnema sylvestre, Morus alba, and red ginseng. The study found that these compounds slow carbohydrate digestion, enhance glucose uptake, and protect organs from oxidative stress.