Researchers found that just one simulated night shift altered levels and time-of-day patterns of over 100 proteins in the blood. These disruptions can lead to higher diabetes rates and decreased energy expenditure, highlighting the importance of timing treatments around the circadian clock.
A new study published in The Journal of Physiology found that proper maternal care can significantly reduce abnormalities in the offspring's body clock, leading to a lower likelihood of developing heart disease. This suggests that early life experiences may play a crucial role in shaping an individual's health later in adulthood.
The American Physiological Society honors four distinguished physiologists with Distinguished Lectureships. Ole H. Petersen presents on pancreatic physiology and pathophysiology, while Yatrik M. Shah discusses oxygen sensing pathways and their link to cancer. Merry L. Lindsey shares her top five mentoring tips in her lecture.
Researchers at UCLA have developed a new method that enables them to observe astrocytes' influence on nerve-cell communication in real time, shedding light on their role in neurological disorders such as Alzheimer's and Huntington's disease.
A $3.4 million grant will help researchers study endocrine-disrupting chemicals in medical devices, with a focus on improving transfusion safety and understanding the impact on cardiovascular health.
University of Tennessee assistant professor Tyson Raper received the 2018 Dr. J. Tom Cothren Outstanding Young Cotton Physiologist Award for his research contributions to cotton physiology. He leads education and research efforts on cotton, wheat, and small grain crops.
Hawkeye's advanced eyesight can be used to explain the physiology of the human eye and its limitations. This can lead to discussions on genetic engineering, wearable technologies, and responsible innovation in genetics. The article suggests using Hawkeye as a tool for engaging students in scientific communication and outreach.
Research published in Experimental Physiology found that Bikram yoga, practiced at room temperature, shows similar benefits to traditional yoga for vascular health and atherosclerosis prevention. The study isolated the effects of heat on Bikram yoga, finding no benefit from heated environment.
Researchers found that Antarctic fish can adapt to warmer waters but are unable to withstand both climate stressors simultaneously. The study suggests these fish must use their existing physiology, which is limited, to cope with the challenges.
Research published in The Journal of Physiology found that elderly people walk at a slower speed and tire more quickly due to muscle loss. Building up leg muscles may be the only way to improve elderly walking, according to the study's findings.
A Penn-led team discovered that midshipman fish release small amounts of calcium to sustain their muscle contractions for an hour, allowing them to produce a sustained hum. This finding sheds light on the physiology behind this extraordinary ability and may apply to other animals moving at high speeds.
Scientists have determined the kinetic cycle of a potassium channel at atomic resolution, allowing for more precise targeting of specific spots within the channel structure. This breakthrough could lead to the creation of new drug molecules that can correct potassium channels dysfunction, addressing conditions such as epilepsy and diab...
Researchers studied six healthy young male volunteers to collect physiological information as they went about their daily lives, measuring thousands of physiological indicators. The study found that most sensor readouts showed time-specific variability, including blood pressure, heart rate, and cortisol levels.
Research published in Experimental Physiology found that spinal cord injury affects the heart, with changes dependent on injury severity. The study suggests preserving more nerve fibers can improve heart function in individuals with spinal cord injury, who are at higher risk of heart disease.
A team of scientists used a novel microscope to measure the orientation of integrins on cell surfaces in real-time, revealing that actin flow inside the cell aligns with external forces. The study provides new insights into how cells migrate towards wounds or pathogens, shedding light on the fundamental mechanisms of cellular movement.
Researchers at Saint Louis University report promising results slowing DMD progression using SR8278, a nuclear receptor regulator drug that increases lean mass and muscle function while decreasing fibrosis and protein degradation.
Researchers discovered a novel mechanism of estrogen action on heart physiology, revealing that xenoestrogens can influence cardiac function by regulating thyroid hormone production. This study highlights the potential risks of environmental estrogens on human health.
A team of scientists discovered that a major cause of variation between genetically identical C. elegans worms is their mother's age, particularly in younger mothers. The study found that the youngest mothers produce offspring with impaired characteristics such as size, growth rate, and starvation resistance.
New research finds that eating breakfast decreases genes involved in fat metabolism and increases sugar uptake in fat cells. This may lead to lower diabetes and cardiovascular risk in obese individuals.
New research challenges common perception that polar species are best at adapting to changing temperatures. Acclimation is most effective at temperate latitudes, with slow seasonal changes allowing for optimal adaptation. This could alter our understanding of which species are most vulnerable to climate change.
A new review article argues that incorporating natural variability into experiments can provide more accurate insights into the effects of climate change on corals and other reef organisms. Studies found that varying factors such as temperature and pH can affect the physiology and response to future changes, warranting further research.
Researchers at Kent State University will investigate the use of probiotics during exercise in a hot environment. The study aims to understand how probiotic supplementation affects physical performance, psychological status, and cognitive function under heat stress.
A comprehensive study of heart-spleen and heart-kidney networks reveals the interconnectedness of organ damage after a heart attack. Researchers found histological and cellular changes in the spleen and kidney, as well as bimodal inflammatory responses and irreversible dysregulation in the cardiosplenic and cardiorenal networks.
Research found that eating fat at night leads to higher blood fat levels, a risk factor for heart disease and diabetes. The study's findings suggest ignoring the body's natural 24-hour cycle can harm health.
Research finds that late preterm babies, born at 35 weeks, are more likely to develop altered heart control and increased cardiovascular disease risk. Adult premature males also show decreased blood pressure regulation.
A new high-throughput system enables rapid and standardized mouse behavior and physiology studies, reducing experimental animal usage and time requirements. The system aims to facilitate reproducibility and data sharing, addressing issues of varying training protocols and data comparison across labs.
A study published in Journal of General Physiology investigated the functional effects of specific mutations in Na/K pumps found in tumors that induce primary aldosteronism. The researchers found that impaired sodium and potassium transport is a common mechanism behind the pathology, contradicting previous 'gain-of-function' proposals.
A new study analyzes Google Trends data across eight countries, finding summer and fall seasons correlate with greater hair loss. The findings provide evidence for seasonality in hair loss at a population level, supporting future research into the physiology of the hair cycle.
A team of scientists developed an innovative way to prevent sleeping sickness in cattle using the smell of antelopes. By mimicking the waterbuck's repellent scent, more than 80 percent of cows were spared from infection. The method is cheaper and more popular among Maasai herders than traditional treatments.
A team of researchers is working on a computer software that can deliver better therapies for patients with life-threatening heart failure. The computer model will take MRI or genetic data of a patient and build a multiscale simulation of their heart, leading to more personalized treatment plans.
A new study published in The Journal of Physiology found that pregnant women who sleep on their backs during late pregnancy may be at increased risk of late stillbirth. Fetal activity levels were lower when mothers slept on their backs, suggesting a potential link between maternal position and fetal wellbeing.
Researchers will investigate how individual differences in stress response affect escalation of alcohol drinking after traumatic stress, with potential treatments for vulnerable populations. The study aims to identify neurobiological targets for treating alcohol abuse in PTSD patients.
Brandon Cooper, a new University of Montana faculty member, has received a $1.8 million grant from the National Institutes of Health to investigate the effects of Wolbachia bacteria on insect physiology and fitness. The study aims to understand how these bacteria spread within and between host species.
Michael W. Young, a Rockefeller University biologist, has been awarded the Nobel Prize in Physiology or Medicine for his groundbreaking work on circadian rhythm. His research revealed the molecular mechanisms that govern biological clocks, which regulate sleep, eating behavior, and metabolism.
A team of researchers at Kansas State University is partnering with NASA to study the health and fitness levels of astronauts during emergency escape maneuvers. They are using a mock space capsule to test the strength, cardiovascular health, and aerobic capacity needed for a safe landing or escape.
Researchers at the University of Bonn have developed a new compound extracted from coralberry leaves that effectively relieves bronchial spasms and may be more effective than common asthma medication salbutamol. The study was conducted in mice, but further human trials are needed before its application.
A team of marine biology researchers from King Abdullah University of Science and Technology (KAUST) identified key mechanisms that enable corals to adapt to environmental changes. The study suggests that microbes play a vital role in coral physiology, allowing them to adjust quickly under changing conditions.
The University of Arizona is conducting a Phase 2 trial to determine whether the peptide angiotensin 1-7 can mitigate or reverse cognitive deficits after bypass surgery. The trial involves administering the compound before and after surgery, with participants undergoing regular tests to evaluate their memory.
A comprehensive taxonomic summary of all recognized species of crayfish worldwide has been created. The updated classification includes five families and 38 genera, and will impact various fields such as physiology, ecology, neurobiology, conservation, and evolution.
Recent reports on gymnosperms' slow photosynthetic use of sunflecks prompted a call for cycad species study. Experimental protocols should be defined from natural habitats to accurately represent species behavior.
Researchers have developed a new skin cell model to study the genetic mutation ACTA2-R258C, which is linked to early-onset aortic aneurysm and moyamoya-like cerebrovascular disease. The study found that the mutation disrupts cytoskeleton functions, leading to impaired smooth muscle contraction and increased risk of heart disease.
Researchers at Wyss Institute have enhanced Organs-on-Chips technology to monitor cell health and electrical activity, enabling the study of human organ physiology and potential drug responses. The new design allows for real-time assessment of trans-epithelial electrical resistance and electrical activity of living cells.
SLU researchers have made a breakthrough in understanding muscle regeneration, identifying the nuclear receptor REV-ERB as a key player. By targeting this receptor, scientists may be able to develop new drugs to treat a range of muscle disorders and injuries, including muscular dystrophy and sarcopenia.
Researchers found that HDAC3 inhibitors increase expression of aquaporin-3, a channel that transports glycerin, helping to improve skin health and reducing inflammation. The study's findings suggest that HDAC inhibitors could be an effective therapy for psoriasis.
The Moscow State University has opened a new cryobank to store biotechnological plant material, including rare species cell cultures. The facility aims to prevent cross-contamination by storing biological samples in nitrogen vapor, not liquid nitrogen.
A large dataset reports that deferring revascularization in patients with intermediate stenosis leads to fewer interventions. The rate of major adverse cardiovascular events (MACE) was low, especially in those without acute coronary syndromes.
Young veterans with combat-related PTSD have an increased 'fight or flight' response during mental stress, contributing to higher risks of high blood pressure and cardiovascular disease. Researchers found that these individuals had higher adrenaline levels and less control over their heart rate in response to blood pressure changes.
Researchers at Kansas State University found that astronauts' exercise capacity decreases by 30-50% due to decreased oxygen transport efficiency. This decrease can impact astronaut performance and has implications for understanding blood vessel function in older patients with heart failure.
A recent study by UPV/EHU-University of the Basque Country suggests that high-intensity interval training can cause a significant decline in brain oxygenation among elite athletes, particularly Kenyans. This finding has implications for understanding human performance and endurance.
Researchers connect classical acupuncture to advances in physiology, systems biology, and mechanotherapeutics. They explore the body's interconnectedness as a whole system, suggesting an exciting convergence in Eastern and Western medicine.
Researchers develop new method to calculate indoor CO2 concentrations more accurately, using established concepts from human metabolism and exercise physiology. The new approach considers body size, composition, diet, and physical activity to provide a more reliable estimate of CO2 generation rates.
Dr. Chad M. Walesky receives the ASIP Young Scientist Leadership Award for his contributions to liver cancer pathogenesis, including a novel function of HNF4α as a tumor suppressor. His work has been published in top journals such as The American Journal of Physiology and Hepatology.
Rats that experience past episodes of limited food resources develop physiological adaptations to conserve energy and survive prolonged starvation. Researchers found that starved rats have lower body temperatures and blood sugar levels than fed controls, allowing them to hold onto stored fat for energy.
Scientists have identified a molecular mechanism by which E. coli bacteria regulate lipid storage in C. elegans, leading to increased fat accumulation and mitochondrial fragmentation. This discovery reveals unsuspected connections between bacteria and mitochondria, suggesting a new language for communication between the two.
The American Physiological Society's (APS) Porter Physiology Development Fellowship has supported 140 minority doctoral and postdoctoral researchers in the study of physiological sciences. Since its inception in 1967, the program has increased diversity in physiology and within APS membership.
The American Physiological Society has announced its 2017 Distinguished Lecturers, who will present talks at Experimental Biology. The winners include Michael J. Welsh, Brant Isakson, and Kurt Albertine, recognized for their lifetime achievement and contributions to physiology.
A new study by researchers at the University of California, Davis and the University of New Hampshire found hundreds of differences in gene activity between male and female rock doves. The findings aim to promote sex and gender inclusion in experimental science and shed light on physiological differences between sexes.
A team of physicists, biologists, and bioengineers from UC San Diego developed a new
A recent study published in the American Journal of Physiology - Endocrinology and Metabolism suggests that increasing dietary potassium intake can have an equally important effect on hypertension as decreasing sodium intake. Eating foods high in potassium, such as sweet potatoes, avocados, and spinach, may help lower blood pressure.
Researchers found that mitochondrial-nuclear interactions affect energy production in animal cells, leading to variations in traits and potentially influencing human health. The study suggests that metabolic fitness relies on these interactions, which have significant implications for physiology and medical interventions.