A comprehensive systematic review and meta-analysis of testosterone treatment for women found significant improvements in sexual desire, function, and pleasure. Non-oral formulations appear to have fewer side effects compared to oral testosterone, with benefits including reduced concerns and distress about sex.
A study published in the Journal of Endocrinology found that high levels of caffeine during pregnancy can lead to lower birth weights, altered growth hormone levels, and impaired liver development. The study suggests that excessive prenatal caffeine consumption may increase the risk of fatty liver disease in adulthood.
A nationwide study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that high blood sugar levels significantly increase the risk of pancreatic cancer. The study suggests that early detection of hyperglycemia and lifestyle modifications to improve glucose profiles may help lower this risk.
A mouse study published in the Endocrine Society's journal Endocrinology found that BPA exposure may contribute to autism by disrupting nerve cell connections in the brain. Mice exposed to BPA during pregnancy showed social behavioral deficits similar to autistic behavior.
A randomized clinical trial found that patients taking IDegLira achieved and maintained lower blood glucose levels for longer periods compared to those taking insulin only. The study showed improved outcomes without the need for additional therapy, reducing side effects often associated with insulin-only treatment.
Two new trials show oral semaglutide is more effective than subcutaneous liraglutide in treating type 2 diabetes, with the latest trial showing it's also safe for patients with moderate renal impairment. Another trial found that insulin degludec plus liraglutide is a durable therapy option for type 2 diabetes.
Research suggests that exposure to phthalates, commonly found in everyday items, may increase the risk of metabolic disorders such as obesity and diabetes. Higher levels of phthalate exposure were associated with markers of impaired liver function, insulin resistance, and cholesterol in people with obesity and diabetes.
Top female athletes have higher testosterone levels, which enhance physical performance and raise questions about fairness in competition. The European Society of Endocrinology recommends a maximum testosterone level of 5.0 nmol/L for female athletic events to ensure competitive fairness.
Exposure to environmental pollutants alters brain development, affecting sexual development and fertility for multiple generations. Research suggests that current levels of endocrine-disrupting chemicals may already be causing long-lasting harm.
Limiting evening exposure to light-emitting screens can improve sleep quality and reduce symptoms of fatigue and bad mood in teenagers. A one-week study found that adolescents who reduced screen time experienced earlier wake-up times and fewer symptoms of sleep loss.
Anabolic steroids pose significant health risks, including damaged sperm and increased risk of heart disease and liver damage. Men are often aware of these risks but choose to continue using steroids to improve strength and physical performance.
Women who breastfed their babies are less likely to develop heart disease later in life, with a stronger effect seen in women who breastfed for longer periods. The study's findings provide further evidence for the long-term health benefits of breastfeeding and its potential role in reducing cardiovascular disease risk.
A study using family-based genetic analysis has identified the DENND1A gene as playing a major role in PCOS, enabling personalized medicine approaches and better disease prediction. The findings suggest that rare genetic variants in this gene contribute to the disorder's distinctive hormonal profile.
A study published in The Lancet Diabetes & Endocrinology journal found that metformin can halve the risk of late miscarriage and preterm births for women with polycystic ovary syndrome (PCOS). Women who received metformin during pregnancy also gained less weight, but there was no effect on gestational diabetes or pre-eclampsia.
A study published in Fertility and Sterility found that female reproductive endocrinology and infertility subspecialists make $67,000 less than their male counterparts annually. Researchers attribute the pay gap to factors such as salary compression and women's reluctance to negotiate over salary.
A study found that economic growth in China led to a decrease in stunting and thinness among children and adolescents, but a significant increase in overweight and obesity rates. The research suggests a need for policies promoting dietary diversity, physical activity, and health education.
A new study suggests that short-term strength training can improve liver health and blood sugar regulation in obese mice. The findings indicate that strength training may be a fast and effective strategy for reducing the risk of diabetes and fatty liver disease in obesity. However, further research is needed to confirm these results.
Researchers at Osaka University found that activated adipocyte GRs restrict healthy fat expansion, causing metabolic disturbances such as insulin resistance and liver steatosis. Adipocytes are the primary sites of steroid action, contributing to the development of steroid diabetes.
A new study published in Cell Metabolism suggests that energy balance - the calories consumed versus burned - may not determine the development of gestational diabetes. Women with obesity tend to develop gestational diabetes due to primary risk factors such as excess fat and insulin resistance, which can be evident early in pregnancy.
A Texas A&M-led study reveals that transcription factor Foxo1 plays a crucial role in regulating blood glucose levels and may serve as a key therapeutic target for preventing Type 2 diabetes. By understanding the molecular mechanism of Foxo1, researchers aim to develop novel interventions for controlling blood glucose homeostasis.
Researchers found that participants who completed mindfulness training lost an average of 3 kilograms more than those who did not attend the course. The study suggests that mindfulness techniques can help improve eating behavior and facilitate successful weight loss in individuals with obesity.
Researchers found that hysterectomy in rats with intact ovaries led to a memory deficit, suggesting the uterus may have functions beyond reproduction. The study tested rats with different types of menopause surgical interventions and found that only those with just the uterus removed had a negative effect on working memory.
Scientists from the Diabetes Research Institute renewed their original theory that pancreatic progenitor cells exist and can regenerate in humans. The study's findings could potentially address a major challenge in type 1 diabetes by regrowing patients' own insulin-producing cells.
A study published in Clinical Endocrinology found that DHEA therapy increased bone mineral density in older women, particularly in the lumbar spine, total hip, and trochanter. However, the increases were not as large as seen with other treatments like bisphosphonates.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism reveals weight cycling is associated with a higher risk of death. Conversely, weight loss from weight cycling can reduce diabetes risk in people with obesity.
Researchers found that areas with higher rat complaints had increased trap rates and more garbage, suggesting a correlation between waste and rodent abundance. The study also revealed neighborhoods with high rental units tended to have more rats, possibly due to increased trash and access points.
A new study suggests that regular vitamin B12 screening in metformin-treated type-2 diabetes patients can reduce the risk of irreversible nerve damage. The study found that nearly 70% of patients were not being checked for vitamin B12 levels, despite a link to peripheral nerve damage.
A global study predicts a 20% increase in insulin use by 2030 due to rising type 2 diabetes cases. Without improved access, nearly half of the 79 million adults with type 2 diabetes will not receive insulin.
A new study suggests that antioxidants can reduce cognitive impairments caused by low blood sugar in diabetic patients. The research found that stimulating antioxidant defenses with sulforaphane improved cognitive ability in mice, indicating potential benefits for humans.
A new study found that inflammatory skin disorders like psoriasis increase the risk of type-2 diabetes. Improving skin health could be crucial for controlling blood sugar levels and reducing diabetes risk.
Research using young mice suggests that a nutrient-rich diet during early-life stress can improve brain development and function. The study found that micronutrients could help mitigate the negative effects of early-life stress on cognition, suggesting potential benefits for children's learning and memory abilities.
A new study reveals that women can be as resilient to extreme physical activity as men, contrary to previous claims about gender differences. The research found no significant negative health effects in six female participants who completed a transantarctic expedition.
A live debate at the Society for Endocrinology annual conference explores the roles of gut and brain hormones in regulating appetite and metabolism. Experts argue over whether the gut or brain is more important, with implications for treating obesity and diabetes.
Children's hospitals will use electronic health records and DNA samples to identify genetic markers for severe pediatric growth disorders, enabling early diagnosis and targeted treatments.
A recent study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that midlife women transitioning to menopause have a higher risk of developing metabolic syndrome. The study identified central obesity as the most common factor, but also showed that physically active women were less likely to deve...
Consuming too much vitamin A may decrease bone thickness and increase fracture risk in humans. A recent study found that mice exposed to lower doses of vitamin A equivalent to 4.5-13 times the recommended daily allowance showed significant weakening of bones over a 10-week period.
A large meta-analysis of 81 randomised trials found no effect of vitamin D supplementation on bone mineral density, fractures, or falls in adults. The study suggests that clinical guidelines should be changed to reflect the best available evidence and that there is little justification for using vitamin D supplements for musculoskeleta...
Researchers found that lixisenatide slowed the progression of kidney damage in patients with macro-albuminuria and type 2 diabetes. The study showed a statistically significant reduction in urinary albumin-to-creatinine ratio and a borderline significant reduction in risk of incidence of macroalbuminuria.
Researchers found that vitamin B complex supplementation improved blood glucose regulation and kidney function in children with type-1 diabetes. The study suggests that simple supplementation may be a safe and cost-effective strategy for early protection of kidney function.
A study of 232 obese children found that vitamin D supplementation led to significant reductions in body mass index and body fat. This suggests a potential role for vitamin D in reducing the risk of serious health problems, such as heart disease and diabetes, later in life.
A study suggests that childhood habits, including diet and physical activity, can shape the gut microbiota of teenagers, which may contribute to developing conditions like diabetes and cardiovascular disease. Healthy lifestyle habits during childhood appear to promote a balanced gut microbiota in late adolescence.
A meta-analysis of 99 studies found that levothyroxine, a common medication for hypothyroidism, is inadequate in controlling high cholesterol levels. The study's findings suggest that patients may require additional therapies or adjustments to their treatment plans.
A study found that people with prediabetes who prefer to be active and alert later in the day tend to have higher body mass indices compared to those with morning preferences. This association is partly due to lack of sufficient sleep, which can increase the risk of obesity and diabetes.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism reveals that broken bones among older people increase their risk of death for up to 10 years. Non-hip fractures, such as femur and pelvic fractures, pose a significant risk of mortality, with a one-year excess mortality rate ranging from 20%...
A recent study found that most adolescents with gynecomastia do not require routine endocrinology assessment and hormone laboratory testing. Most cases of gynecomastia can be identified without such testing, according to the study.
Research from the University of Eastern Finland found a link between higher serum vitamin D levels and lower plasma cholesterol levels in primary school children. Children with sufficient vitamin D levels had lower total and LDL cholesterol levels compared to those with insufficient levels.
An observational study tracking over 100000 men and women found that job strain is associated with a higher risk of premature death in men with coronary heart disease, stroke, or diabetes. Despite achieving treatment targets, men experiencing job strain had a 68% greater risk of death compared to those with no job strain.
Universal thyroid testing for pregnant women could detect mild thyroid problems that are currently missed in up to 75% pregnancies. However, experts debate the potential risks and benefits of this approach, with some arguing it may not provide significant improvements in pregnancy outcomes.
A study found that brain activity and structure in transgender adolescents are more similar to their desired gender than their assigned biological sex. This suggests that differences in brain function may occur early in development, making brain imaging a useful tool for earlier identification of transgenderism in young people.
Obese individuals with larger waistlines are at a greater risk of developing vitamin D deficiency. The study found that lower levels of belly fat were associated with lower vitamin D levels in both men and women.
A new brain stimulation technique, dTMS, has shown promising results in reducing food cravings in obese patients. The study found that high-frequency dTMS significantly increased beta-endorphins levels, leading to a decrease in glucose and leptin levels, suggesting a potential safer alternative to treat obesity.
Research suggests that everyday products carry environmental chemicals that interfere with hormones, contributing to obesity. By following simple recommendations, such as choosing fresh food and reducing plastic use, individuals can minimize exposure and potentially reduce the risk of obesity.
Fasting every other day impairs insulin function, leading to potential long-term health risks, including type-2 diabetes. This study found that even in normal-weight rats, intermittent fasting diets can cause damage to the pancreas and increase insulin resistance.
A recent case report documents how a patient's use of biotin supplements caused clinically misleading test results, prompting multiple consultations and unnecessary testing. The study highlights the need for caution when using biotin supplements, as they can interfere with certain lab tests.
A new study reveals that a family history of obesity is a significant risk factor for early onset and severity of childhood obesity. The research found that the youngest children were the most severely obese and showed signs of insulin resistance, increasing the risk of developing type 2 diabetes.
A UAB-led study published in The Lancet Diabetes & Endocrinology found that denosumab was superior to risedronate in increasing bone density in patients with glucocorticoid-induced osteoporosis. The 12-month study enrolled 795 patients and showed promising results for the new drug.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that girls with recently diagnosed type 2 diabetes had a high rate of menstrual irregularities. Many of these girls also had high testosterone levels, suggesting PCOS as an underlying cause.
The Biochemical Society has announced the winners of its annual awards, recognizing established and early-career researchers in cell biology, endocrinology, and plant sciences. The award recipients include Dr Melina Schuh, Professor Dame Caroline Dean, and Professor R. John Ellis.
A new study published in the Journal of Clinical Endocrinology & Metabolism found that menopausal hormone therapy users tend to have less abdominal fat tissue than other menopausal women. The protective effect disappeared rapidly after treatment stopped.
Low levels of vitamin D during pregnancy and breastfeeding have been linked to differences in social behavior in children later in life. The study found that rats born to mothers with vitamin D deficiency displayed abnormal social behaviors, altered brain chemistry, and impaired learning and memory.