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Fundação de Amparo à Pesquisa do Estado de São Paulo


Researchers warn of the need for Brazil to turn promises into practical actions at COP30

Researchers warn that Brazil's domestic policies must align with international commitments on forest conservation and climate justice. The country must take concrete actions, such as reversing anti-environmental policies and protecting indigenous peoples' rights.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalInternational Environmental Agreements Politics Law and Economics·DateNov 20, 2025

Gene editing produces plants that are indigestible to pests

Researchers have made significant advances in genetically modified plants that produce alpha-amylase inhibitor proteins, making them indigestible to pests like bedbugs, beetles, weevils, and woodworms. Gene editing techniques, such as CRISPR, offer a promising solution to combat insect pests without compromising human consumption.

Rainfall and temperature shape mosquito fauna in Atlantic Forest bromeliads, including malaria vectors

A recent study found that rainfall and temperature significantly impact the water volume in bromeliad tanks, which in turn affects mosquito development and species diversity. This knowledge can be useful for predicting malaria transmission risk and estimating the effects of climate change on disease outbreaks.

Mindfulness improves the health of women with chronic jaw pain

A study conducted at the University of São Paulo found that mindfulness can help reduce pain sensitivity and improve emotional regulation in women with TMD. The research involved 53 women who participated in an eight-week mindfulness program, showing significant improvement in pressure pain threshold and reduction in painful points.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalJournal of Oral Rehabilitation·DateNov 4, 2025

Biosensor identifies protein linked to depression and schizophrenia in saliva

Researchers at the University of São Paulo developed a low-cost, portable biosensor that can quickly identify altered levels of BDNF associated with psychiatric disorders. The device detects extremely low concentrations of BDNF in human saliva, which is crucial for growth and maintenance of neurons and development of brain functions.

Plant biomass substance helps combat weeds

A study found that lignin, a polymer from plant cell walls, can improve the performance of nanoparticles with herbicide. Lignin was subjected to a green process and showed distinct properties, making it suitable for customizing different applications. The substance demonstrated potential for sustainable agricultural pest management.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalACS Sustainable Chemistry & Engineering·DateOct 29, 2025

South American long-necked dinosaur could easily stand on two legs

Researchers used computational engineering techniques to simulate weight and gravitational stress on sauropod femurs. They found that two South American genera, Uberabatitan and Neuquensaurus, could generally remain standing for extended periods, allowing them to feed on high branches and defend against predators. The simulations sugge...

Technique allows estimation of the force acting on each grain of sand in a dune

Brazilian researchers have developed a technique that estimates the force exerted on each grain of sand in a dune from images, enabling the study of previously unmeasurable physical processes. The method uses numerical simulations and artificial intelligence to transform the study of granular system dynamics.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalGeophysical Research Letters·DateOct 23, 2025

Portable sensor detects synthetic cannabinoids in e-cigarettes and biological fluids

Researchers developed a portable sensor to detect synthetic cannabinoids in e-cigarette liquids and biological fluids, allowing for early intervention and harm reduction. The device shows high selectivity and sensitivity, detecting concentrations as low as 0.2 µM and identifying specific peaks that quantify substances present.

Super-resistant bacteria found in wild birds at a rehabilitation center on the coast of São Paulo state, Brazil

Antibiotic-resistant Escherichia coli clones were found in two colonized birds, a vulture and an owl, at the Santos Municipal Orchid Garden rehabilitation center. The presence of these strains in animals raises concerns about potential impact on wildlife health.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalVeterinary Research Communications·DateSep 25, 2025

Group creates tool to predict whether multiple sclerosis medication will be effective for patients

Researchers have developed a tool that can predict how patients with multiple sclerosis will respond to natalizumab treatment, allowing for targeted treatments with fewer side effects. The tool uses high-content imaging and machine learning to analyze cell morphology and identify individuals who are unlikely to respond to the medication.

Study identifies candidates for therapeutic targets in pediatric germ cell tumors

Researchers have identified distinct immune profiles for different subtypes of pediatric germ cell tumors, which could lead to more targeted therapies. The study found that certain tumor subtypes respond well to immunotherapy and others exhibit an immunosuppressive environment, making them more aggressive.

Plant-derived compound has antimicrobial and anti-inflammatory effects against periodontal disease

Researchers developed a powder based on morin, extracted from plants like guava leaves, apple peels, and figs, to combat periodontal disease. The study found that the substance can be slowly released through polymers, providing an alternative to antibiotics for controlling microorganisms.

Green tea improves insulin sensitivity and glucose tolerance in obese mice

A recent study found that green tea extract improved glucose sensitivity and insulin resistance in obese mice, preserving muscle morphology. The treatment reduced body weight by up to 30% and increased the expression of genes related to glucose metabolism, suggesting a selective effect on excess body fat.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalCell Biochemistry and Function·DateSep 10, 2025

Variations in glucose levels may indicate severity of heart attack damage

Research in Brazil found that glycemic delta, a measure of blood sugar variability, is associated with the size of the heart attack and the strength of heart contractions. The study suggests that high glycemic delta may be a biomarker for worse outcomes in patients who have experienced their first acute myocardial infarction.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalDiabetology & Metabolic Syndrome·DateSep 4, 2025