A higher rate of sudden infant death syndrome (SIDS) was observed among siblings of children who died of SIDS compared to the general population. Shared genetic and/or environmental factors may contribute to this clustering of SIDS, warranting consideration of family history in clinical assessments.
A study published in the Journal of Occupational Health found that certain occupations in South Korea are associated with a higher risk of pregnancy loss. Women in health and social work, manufacturing, and education had increased risks of no live births and early abortive outcomes.
A new study finds that many US coastal communities rely on low estimates of sea level rise, omitting high-end scenarios that could result in costly and dangerous underestimates. The study's authors hope to identify and address gaps in how communities use the most recent assessments of sea level rise in their policy decisions.
A systematic review and meta-analysis of 17 studies found mRNA COVID-19 vaccination to be associated with lower risks of SARS-CoV-2 infections, severe illnesses, and hospitalizations. While vaccination was linked to higher adverse event rates, the frequency of severe adverse events remained low.
Research published in BMJ Open found that carrying excess weight from mid-life onwards increases the risk of physical frailty in older age. The study tracked over 4500 participants and found that obesity and high waist circumference were associated with a higher risk of pre-frailty/frailty, highlighting the importance of maintaining a ...
Insufficient sleep during teenage years is linked to a higher risk of developing multiple sclerosis (MS). Short sleep duration and poor sleep quality are associated with a 40% and 50% increased risk, respectively. The study suggests that sufficient restorative sleep may be an important preventive factor against MS.
A new study led by Mayo Clinic researchers found that women carrying specific genetic changes, such as BRCA1 and BRCA2, have a twofold increased risk of developing contralateral breast cancer. Premenopausal women with these mutations are more likely to develop cancer in both breasts.
A new American Heart Association scientific statement emphasizes the importance of rapid evaluation for TIA, which can lead to full-blown stroke. The statement offers a standardized approach to evaluating people with suspected TIA, including guidance for hospitals in rural areas with limited resources.
Researchers analyzed data from the VITAL trial and found that vitamin D supplementation increased biomarkers associated with vitamin D metabolism in people, regardless of their weight. However, these increases were significantly smaller in people with elevated BMIs, suggesting a blunted response to supplementation.
Researchers found that p53 mutations in blood cells increase the risk of developing coronary heart disease and peripheral artery disease. The study provides solid evidence for the link between acquired p53 gene mutations and cardiovascular disease, suggesting a potential new risk factor.
A pooled data analysis of international evidence finds that COVID-19 infection during pregnancy nearly doubles the risk of maternal death and severe illness. Babies born to infected mothers are also at increased risk of premature birth and low birth weight.
Researchers found that global wave models can vary in their estimates of extreme wave heights by up to 20 feet, which can lead to underprotected areas during extreme events. The study emphasizes the need for considering multiple models and modern observational data to better assess offshore and coastal risks.
A school-based gardening, nutrition, and cooking intervention improved glucose control and reduced low-density lipoprotein cholesterol in high-risk youth. Elementary schools can incorporate garden-based interventions to improve metabolic parameters in children.
A recent study from the University of Eastern Finland concludes that EU regulation does not adequately consider the environmental emissions of pharmaceuticals in global manufacturing supply chains. The researchers argue that the current GMPs and ERA regulation are limited in scope and weight, and do not prevent the release of pharmaceu...
A team of researchers from Xi'an Jiaotong-Liverpool University and other institutions has identified a flexible and user-friendly model for predicting flood frequency in a changing environment. The fractional polynomial-based regression method is more effective than existing models, which often fail to account for factors like climate ...
A Rutgers study found that military service members who hide their suicidal thoughts and avoid behavioral health care tend to store their firearms unsafely. Those with undisclosed past year suicidal thoughts stored their firearms at home more often and with a locking device in place less often.
A new study published in The Lancet HIV reveals that women experiencing recent intimate partner violence are three times more likely to contract HIV. The research highlights the intersectional epidemic of IPV and HIV in Sub-Saharan Africa, where women face increased risk of HIV acquisition and less frequent viral load suppression.
Research from Karolinska Institutet found high levels of antibiotic residues in waterways, including wastewater and drinking water, in regions such as China and India. The study suggests these residues contribute to antibiotic resistance, a global threat to human health.
A predictive model developed by University of Groningen researchers can identify cows at risk of dystocia before insemination. The model, which uses machine learning on a large dataset, suggests that it could roughly halve the risk of calving problems.
A Mediterranean diet has been associated with a reduced risk of adverse pregnancy outcomes. The study found a dose-response relationship between the intake of Mediterranean diet and lower risk of such outcomes.
A nationwide cohort study in Sweden found that elite male football players have a lower risk of alcohol and drug related disorders compared to the general population. This protective effect was seen only for those who first played in the 1960s and later, while players from earlier eras had similar risks as men from the general population.
A new study found that drinking two or more cups of coffee daily may increase the risk of cardiovascular disease mortality among people with severe hypertension. In contrast, moderate green tea consumption did not show a significant association with increased risk, suggesting potential benefits of polyphenols in reducing mortality.
A comprehensive analysis of over 100,000 colorectal cancer cases identified 100 new genetic risk factors strongly linked with the disease. These findings could help clinicians determine who's at highest risk for early detection and potentially identify candidates for preventive treatments.
Researchers at Michigan Medicine have developed a new biomarker-based strategy to screen for immune checkpoint inhibitor-induced myocarditis, which can cause muscle damage and liver injury. Early detection of these biomarkers can lead to earlier treatment and improved survival rates.
The University of Texas at El Paso will establish a national Center for Collective Impact in Earthquake Science, addressing low-probability but high-impact earthquake risk and community needs. Researchers aim to develop leading-edge earthquake research projects and integrate diversity into their work.
A large real-world study has confirmed that COVID-19 vaccination is more effective than natural immunity in preventing death, hospitalizations, and emergency department visits for any cause. Vaccinated individuals had a 37% lower risk of all-cause death and hospital admission rates compared to those with natural immunity.
A study of nearly 4,000 patients found that the longer the time between COVID-19 diagnosis and surgery, the greater the risk of major cardiovascular events during or following surgery. This association could inform discussions on optimal surgical timing and perioperative outcomes for patients with a history of COVID-19 infection.
The Tokyo 2020 Paralympic Games reported a lower overall injury rate of 8% compared to previous Games, but injuries sustained were more severe. Newly introduced sports of taekwondo and badminton had high injury rates, prompting calls for prevention measures.
A retrospective cohort study of 1,404 subjects with type 2 diabetes found that metformin use reduced the risk of delirium by 50% and decreased 3-year mortality rates. The study suggests that metformin may be a potential benefit for patients with diabetes, particularly in reducing age-related disorders such as dementia.
Lying prone reduces the risk of needing a breathing tube in COVID-19 patients by 24.2% compared to usual care, but evidence for its effect on mortality or other outcomes is inconclusive. The intervention also results in 55 fewer intubations per 1,000 patients.
A recent study published in Frontiers in Medicine found that COVID-19 vaccines significantly reduce the likelihood of reinfection and severe symptoms. Vaccinated individuals who have recovered from the virus have a 50% to 60% lower risk of reinfection compared to those who are not vaccinated.
A new study found that 39 out of 43 California's coastal airports have assets exposed to projected flooding by 2100. Sixteen airports have assets within their boundaries, while 23 have assets outside their jurisdiction at risk from flooding. The study highlights the need for collaborative climate adaptation plans to address this issue.
Researchers found that a one-year increase in retinal age was associated with a 10% higher risk of incident kidney failure over 11 years. Retinal age gap, a non-invasive biomarker based on retinal imaging, may help identify people at elevated risk for kidney failure.
A recent study found that consuming the most vegetables, including leafy greens and cruciferous veggies, was associated with a lower risk of developing Type 2 diabetes. Meanwhile, potatoes may not have the same benefits but aren't bad if prepared in a healthy way.
Researchers discover a shared genetic basis between fibromuscular dysplasia (FMD) and abdominal aortic aneurysms (AAA), with males more likely to develop AAA when a family member has FMD. The study suggests that screening for AAA in male relatives of patients with FMD may be beneficial, along with established guidelines.
A study of over 1000 Australian adults found that people with trouble sleeping were more likely to have indicators of poor cardiometabolic health, including inflammatory markers, cholesterol, and body weight. Prioritizing a good night's sleep is crucial for maintaining good health, according to researcher Dr Lisa Matricciani.
Research by Lero and Motion-S found that fitting all UK cars with Advanced Driver Assistance Systems (ADAS) could prevent 24% of road crashes. Automatic Emergency Braking (AEB) is the most impactful technology, reducing three out of four most frequent accident categories.
SourceLero·JournalTransportation Research Interdisciplinary Perspectives·TypeData/statistical analysis·DateNov 28, 2022
Researchers found that individuals with persistent asthma have higher levels of inflammation and artery plaque, which may increase heart attack or stroke risk. The study also highlights the importance of addressing risk factors for cardiovascular disease in people with persistent asthma.
A trial found that extending anti-clotting treatment after a blood clot in the lower leg reduced further clot risk up to two years. Rivaroxaban administered for three months effectively and safely reduced venous thromboembolism compared to six weeks of treatment.
Chugh argues that AI risk assessments raise concerns about human biases and the absence of individualized decision-making in the judiciary. She advocates for more research on AI's role in the court system, prioritizing community-driven and individualized processes.
A large study found that mRNA vaccines increased myocarditis risk in younger males, especially after the second dose. Absolute rates were low, with higher observed rates compared to expected rates.
Researchers used wearable activity trackers to derive health metrics, including heart rate distribution and walking frequency, that correlated with clinically measured parameters. These findings suggest that activity-tracker data can identify surrogate markers of disease severity, enabling remote monitoring and potential personalized t...
A new study analyzed tumor biopsies from patients with newly-diagnosed germinal center B cell lymphoma and found that CREBBP mutations were associated with lower disease-free survival rates. The researchers identified CLMA as a practical tool to translate experimental findings into clinical applications.
Researchers found cannabis users had decreased patency and were 1.25 times more likely to require amputation one year after lower extremity bypass surgery. Cannabis use was also associated with a higher risk of opioid use after discharge.
A new analysis by researchers at Duke University proposes a four-step science-based framework to overcome barriers and enhance the success of early warning systems. The framework involves understanding potential barriers, engaging key stakeholders, identifying promising strategies to overcome barriers, and measuring outcomes.
A new calculator will assess an individual's risk and benefit of taking bisphosphonates for osteoporosis, considering factors such as fracture history and comorbid conditions. The calculator aims to provide personalized guidance on whether a drug holiday is beneficial or not.
A study of 2,400 women found nearly a quarter developed high blood pressure more than six weeks after delivery. The research suggests monitoring during this period could mitigate severe cardiovascular complications.
A pooled data analysis estimates that 24% of teens and young people engage in unsafe listening practices from personal listening devices and 48% attend loud music venues. This translates to a potential risk of hearing loss for 0.67-1.35 billion young people worldwide.
The American Heart Association statement highlights telehealth's benefits in managing cardiovascular disease, including cost-effectiveness and improved rehabilitation. However, challenges like access to broadband internet and privacy security concerns hinder widespread adoption.
An international research team developed an animal-free testing battery to detect developmental neurotoxicity, using human cells instead of animals. The results show that the testing battery is technically feasible and already has a measurement sensitivity comparable to animal experiments.
Using 1980s environmental inventories, researchers found that disaster risk assessment could have predicted the damage from the Great East Japan Earthquake. The study compared composite risk maps from the 1980s with post-2011 hazard maps to show a significant increase in high-risk areas.
The IOF and ESCEO position paper recommends retaining the current WHO diagnostic criteria for osteoporosis, which has served the field well. The paper suggests that distinguishing between diagnostic and intervention thresholds can help improve treatment of patients at high risk of fractures.
A recent study found that exposure to fine particulate matter during pregnancy is associated with delays in children's gross motor, fine motor, and personal-social development. The study of 17,683 infants in Taiwan suggests that protection from air pollution should start during pregnancy.
Research conducted at Linköping University found that screening for atrial fibrillation in older people could increase the chance of preventing stroke while saving money for healthcare systems. The study, based on data from the STROKESTOP clinical trial, suggests that screening can be a cost-effective intervention.
A new study led by Rice University and UCSF researchers found that seizure cycles are linked to age and common triggers, such as illness and menstrual cycles. The study used data from over 1,000 patients aged 2 months to 80 years to develop a statistical model that captures the effect of these factors on seizure risk.
A meta-analysis of over 600,000 patients found that psychological distress assessed with brief questionnaires was associated with nearly a 30% greater risk of cardiovascular disease. The screening process can be easy and efficient for healthcare providers without significant psychology training.
A large contact tracing investigation found no secondary cases of monkeypox, informing estimates of exposure risk and postexposure prophylaxis recommendations. The framework's ease of application and cross-setting use has important applications for future infection prevention efforts.
A higher urine-to-plasma urea ratio is associated with faster decline in eGFR and development of kidney failure in patients with common forms of CKD. This biomarker may improve risk prediction, particularly in low-cost, easily measurable assays.
Regular use of cholesterol-lowering and diabetes-control drugs may lessen the risk of age-related macular degeneration (AMD) in European populations. The pooled data analysis involved 38,694 participants and showed a 15% lower prevalence of any type of AMD with these medications.
A new study found that long-term treatment with intravenous iron improved symptoms and reduced recurrent hospitalizations among people with heart failure and iron deficiency. The treatment was associated with a significant benefit on reducing the risk of heart failure hospitalization and cardiovascular death.