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Semaglutide reduces cocaine use in rats

Researchers at the University of Gothenburg found that semaglutide reduced both cocaine use and relapse in rats, with motivation to keep taking cocaine decreasing by 52%. The study suggests that semaglutide may blunt cocaine's ability to raise dopamine levels in the brain.

SourceUniversity of Gothenburg·JournalEuropean Neuropsychopharmacology·TypeExperimental study·DateSep 5, 2025

Fentanyl detection through packaging

Researchers developed a magnetic resonance technique to detect fentanyl hydrochloride in sealed packages, offering a non-invasive solution. The technique uses Nuclear Quadrupole Resonance (NQR) spectroscopy, which can identify key target nuclei in the drug, allowing for effective detection and potential diversion of large quantities.

SourcePNAS Nexus·JournalPNAS Nexus·DateJul 1, 2025

Barbarian warriors in Roman times used stimulants in battle

Archaeologists have found evidence that Roman-era barbarian warriors used stimulants before battle, including small spoon-shaped objects attached to their belts. The researchers believe that these stimulants may have been widely used throughout history to motivate soldiers and reduce stress and fear during warfare.

SourceDe Gruyter·JournalPraehistorische Zeitschrift·TypeNews article·DateNov 28, 2024

Exploitation of supply chain monitoring loopholes fueled US opioid epidemic, study finds

Pharmaceutical companies exploited a loophole in the DEA's monitoring system, leading to an oversupply of opioids in communities. The study highlights the impact on Black communities, where overdose deaths tripled from 2014 to 2020. High supply chain complexity played a key role in evading regulations.

SourceIndiana University·JournalProduction and Operations Management·TypeData/statistical analysis·DateJun 24, 2024

The drugs don’t work – meditation and training are better at sparking creativity

Researchers debunk rock'n'roll myth, finding narcotics have no effect on inspiration. Instead, complex training programs, meditation, and cultural exposure boost creativity. Training that highlights mental techniques has long-term impacts, while mindfulness activities like meditation also improve imagination in the short term.

SourceUniversity of Essex·JournalPsychology of Aesthetics Creativity and the Arts·TypeData/statistical analysis·DateMar 28, 2023

Children and teens getting spinal surgery don’t need so many opioids, study suggests

A Michigan Medicine study found that patients who received preoperative education on opioid risks and nonopioid pain management options consumed significantly less oxycodone, with only 16 doses used despite similar pain scores. The results suggest a multimodal approach to managing pain can reduce harm and prevent substance use disorders.

SourceMichigan Medicine - University of Michigan·JournalJournal of Pediatric Orthopaedics·TypeRandomized controlled/clinical trial·DateAug 3, 2022

Drug combination reduces narcotic use, manages pain after surgery for teens with scoliosis

A new study suggests that combining two drugs can reduce postoperative opioid use and side effects in adolescents with scoliosis. The combination of intrathecal morphine and oral gabapentin provides more effective pain control, resulting in fewer side effects and lower narcotic consumption.

SourceMichigan Medicine - University of Michigan·JournalJournal of Orthopaedic Surgery and Research·TypeData/statistical analysis·DateJan 4, 2022

Opioid prescribing after rhinoplasty

A review of 173 rhinoplasty patients found that most received opioid prescriptions, averaging 28 pills per patient, yet experienced less pain than expected. The study's results highlight the need for more research on optimal postoperative pain management from rhinoplasty

SourceJAMA Network·JournalJAMA Facial Plastic Surgery·DateSep 6, 2018

Spinal tap needle type impacts the risk of complications

A recent study published in The Lancet found that the use of pencil-point atraumatic needles during lumbar punctures significantly reduces the occurrence of headaches and other complications. The research team analyzed data from over 30,000 patients across 29 countries, showing a more than 50% reduction in headaches and readmissions.

SourceMcMaster University·JournalThe Lancet·DateDec 6, 2017

Radio devices to save rare species from poachers

A joint project between conservationists and electronics experts has developed miniature radio devices using Radio Frequency Identification (RFID) tags to protect endangered cycad plants from poachers. The technology can detect missing plants up to 10 meters away, providing immediate alerts to ranger stations.

Study: 1 out of 5 adult orthopaedic trauma patients sought additional providers for narcotic prescriptions

A study of 151 adult orthopaedic trauma patients found that one in five obtained narcotic prescriptions from multiple providers, leading to increased drug use and longer prescription durations. Patients who 'doctor shopped' used narcotics four times longer than those with single provider care.

SourceAmerican Academy of Orthopaedic Surgeons·JournalJournal of Bone and Joint Surgery·DateAug 11, 2014

How can we improve global access to pain relief?

The authors propose transferring the public health responsibility for controlled medicines from the International Narcotic Control Board to the World Health Organization, citing restrictive drug laws as a major barrier to access. This shift would aim to create better legal frameworks that extricate pain treatment from drug prohibition.

SourcePLOS·JournalPLOS Medicine·DateJan 10, 2012

The death of euthanasia

The term euthanasia is being reevaluated due to its broad meaning, which encompasses not only assisted dying but also palliative care. Experts recommend clear definitions and honest discussion to avoid polarization in the end-of-life care debate.

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateMar 29, 2010