Articles tagged with Autism
A study examining cesarean section delivery and autism spectrum disorder found an initial association between the two, but further analysis of sibling pairs revealed no causal link. The study suggests that unknown genetic or environmental factors may contribute to the increased risk of both cesarean section and autism spectrum disorder.
A study combining clinical assessment, genomic analysis, and electroencephalography identified specific gene combinations in autistic patients that distinguished them from those with intellectual disabilities. This integrated approach provides new prospects for diagnosis and understanding of autism's physiological mechanisms.
Researchers have discovered that infants with superior perception skills are more likely to develop autism symptoms later in life. The study found that enhanced visual searching ability at 9 months old predicted more emergent autism symptoms at 15 months and 2 years of age.
Researchers at Netherlands Institute for Neuroscience found increased synchrony between sensory cortices and subcortical regions in individuals with Autism Spectrum Disorder, contributing to hypersensitivity. This decoupling is thought to reflect the inability to block out irrelevant sensory information.
A UCLA study finds that children with autism spectrum disorder who are overly sensitive to sensory stimuli have brains that react differently, leading to a condition called sensory over-responsivity. The research may lead to interventions that can help improve the lives of these children and their families.
A recent study published in Journal of the American Academy of Child and Adolescent Psychiatry demonstrates that early intensive behavioral intervention improves outcomes for young children with ASD, including intellectual ability and adaptive behavior. The study found no group differences in core autism symptoms immediately post-treat...
A new study reveals that fragile X proteins FMRP and FXR2P play a vital role in the maturation of newly formed adult neurons. Mice lacking FXR2P had impaired learning and memory tasks, suggesting potential therapeutic targets for fragile X syndrome and autism. The study's findings also highlight the importance of fostering new nerve ce...
A recent study published in Molecular Psychiatry found a significant increase in autism rates among children born to teenage mothers and parents with large age gaps. The research also confirmed that older parents are at higher risk of having children with autism.
A new study shows that early intensive autism intervention can lead to improved intellectual ability and reduced autism symptoms in young children. The therapy, known as the Early Start Denver Model, was found to be particularly effective in promoting social and communication skills.
Researchers at Salk Institute found that a low glycemic index diet reduced symptoms of autism in mice, including impaired social interactions and repetitive behaviors. The diet may influence gut bacteria and inflammation, which are linked to the development of autism.
Researchers found that boys with autism exhibit higher levels of stereotyped behaviors and cognitive difficulties than girls, but these sex differences also appear in children without ASD. The study suggests naturally occurring sex differences in all children may contribute to the observed sex differences in autism.
A recent study published in the Journal of the Academy of Nutrition and Dietetics found that children with Autism Spectrum Disorder (ASD) often do not receive adequate nutrients from dietary supplements. Despite supplementation, many children with ASD still have deficiencies in essential vitamins and minerals such as calcium and vitami...
Scientists identify protein MIM as a key player in initiating dendritic spines, which form the basis of neuronal connections. This discovery sheds light on the molecular mechanisms underlying brain diseases with altered dendritic spine density.
A new study reveals that social and sensory overstimulation is the primary driver of autistic behaviors, contradicting decades-old views of autism as a mental retardation. The research proposes that autistic brains are hyper-functional, requiring predictable and structured environments to function optimally.
Research at the University of Montreal found that one night of poor sleep significantly decreases performance on intelligence tests in both autistic and neurotypical children. The study observed disruptions in protective brain waves during sleep, known as 'sleep spindles', which were associated with lower results on verbal IQ tests.
Researchers at the University at Buffalo have identified a genetic mutation that produces certain autistic behaviors in mice. They also found a therapeutic strategy to restore normal behaviors by reversing the disruption of neuronal communication, suggesting a promising treatment for autism.
A study by Penn State researchers reveals that 64% of children initially diagnosed with autism also have apraxia, a rare neurological speech disorder. The Checklist for Autism Spectrum Disorder (CASD) accurately diagnoses autism in children with apraxia, and ongoing screenings are crucial to prevent long-term problems.
Researchers used zebrafish to study the impact of dysregulation of SYNGAP1 and SHANK3 genes on brain development and behavior. The study found that disrupting these genes leads to hyper-excitable behaviors, delayed development, and changes in brain structure.
A new study by GW researcher Valerie Hu found significant sex-dependent differences in brain RORA protein levels, with males having lower baseline levels and stronger correlations with genes regulated by RORA. The findings suggest that RORA deficiency may contribute to the known male bias in autism susceptibility.
A new NIH grant will help researchers at SDSU study brain connections and cognitive abilities in older adults with autism. This is a significant step towards understanding how autism affects individuals across the lifespan.
The Lieber Institute for Brain Development (LIBD) has been awarded a $200,000 grant by the Pennington Family Foundation to investigate the factors contributing to varying outcomes in individuals with autism spectrum disorder. The study aims to identify biological associations that can improve treatment strategies and prevent long-term ...
Researchers used a 3D simulator to test how individuals with Autism Spectrum Disorder process sensory stimuli. Contrary to previous theories, the study found that autistic participants demonstrated intact multi-sensory integration in both coherent and noisy environments.
A study by the University of Pittsburgh found an association between exposure to fine particulate air pollution and an increased risk of childhood autism. The research estimated that children exposed to higher levels of PM2.5 during pregnancy and early life were at a 1.5-fold greater risk of developing ASD.
A NIH-funded study suggests that the presence of companion animals may reduce social anxiety in children with autism. Children with ASDs showed lower skin conductance levels when interacting with peers and companion animals compared to typically developing children.
Researchers found that genetic mutations passed from mothers to sons are more likely to increase autism risk. The study provides a comprehensive genetic picture of autism and may lead to the discovery of biomarkers for diagnosis and targeted treatments.
Research published in Molecular Autism found that male toddlers with autism have distinct brain structure changes compared to females, suggesting separate evaluation and early developmental markers. Additionally, studies suggest a 'female protective effect' through sex differences in genes and prenatal hormones.
New research reveals differences in the brains of girls and boys with autism, particularly in the corpus callosum and social impairments. The study suggests that girls with autism have more severe social impairments than boys, highlighting the need for targeted research and interventions.
A study published in Neuropsychiatric Disease and Treatment found that Catatonia is a treatable cause of regression in individuals with Down syndrome. Patients treated for Catatonia showed improvement, regaining baseline functioning.
Researchers from USC and CHLA found that adapting dental environments to be more calming for children with autism spectrum disorder significantly reduced psychological anxiety and pain intensity. The study used sensory adaptations such as soothing music, gentle lighting, and deep-pressure hugs to create a comfortable environment.
Researchers found that inactivating Lhx2 in mature neurons can reprogram them to process different senses, expanding one region at the expense of another. This discovery provides proof of brain plasticity and may lead to new therapeutic approaches for treating human disorders such as autism.
A 24-week parent training program improved behavioral problems such as irritability and non-compliance in young children with ASD. The study showed that parent training was superior to parent education in reducing disruptive behavior.
A study found girls with ASD were diagnosed at a mean age of 4 years compared to 3.8 years for boys, while girls with Asperger's syndrome were diagnosed at 7.6 years versus 7.1 years for boys. Girls struggled more with social cognition and had less severe mannerisms.
The 2015 Weatherstone Predoctoral Fellowship class of Autism Speaks will pursue two-year research projects under mentorship of leading scientists. The program aims to advance understanding of autism and support essential training opportunities for the brightest young investigators.
A study found that 7% of children diagnosed with autism spectrum disorder (ASD) resolved their symptoms, but most continued to struggle with social and emotional challenges. The children who showed improvement had normal cognition, but residual learning and behavioral issues persisted.
Researchers at WashU Medicine have identified a potential target for treatments for fragile X carriers, who can experience social deficits and milder versions of cognitive and behavioral disorders. A potential way to boost levels of the key brain protein could lead to symptom easing for carriers.
Researchers discovered that parents of children at high risk for autism spectrum disorder reported more early concerns, particularly sensory and motor issues starting at six months. Early parental concerns can be predictive of autism diagnosis, highlighting the importance of talking to parents and taking their concerns seriously.
Researchers found a common genetic link between child prodigies and autism, specifically on chromosome 1. The study identified shared genetic markers in five prodigies and their family members with autism, suggesting a potential genetic component to exceptional abilities.
A comprehensive report by Drexel University's A.J. Drexel Autism Institute highlights poor life outcomes for young adults on the autism spectrum, including high disconnection rates, limited employment and education opportunities, and increased health risks.
A 24-week parent training program significantly reduced disruptive and noncompliant behavior in children with autism, compared to a parent education program. The study found that parent training led to greater reductions in behavioral problems, including tantrums and aggression.
A multi-site study found that parent training reduced disruptive behavior by 48% compared to 32% for parent education. Parent training provided specific strategies for managing serious behavioral problems such as tantrums and aggression.
A large study of over 95,000 US children found no association between the MMR vaccine and an increased risk of autism spectrum disorders (ASD), even among those with older siblings already at higher genetic risk for ASD. The study suggests that parents' concerns about the vaccine's link to ASD may be unfounded.
A 24-week parent training study by Ohio State University Wexner Medical Center significantly reduced disruptive behavior in children with autism. The study showed that parent training was more effective in reducing behavior problems than parent education, with 70% of children showing a positive response.
A new study published in Biological Psychiatry found no genome-wide significant associations between genetic variants and autism spectrum disorder. Instead, the researchers suggest that clinical variability in autism may be due to factors such as epigenetic changes or environmental responses. The study's results have implications for f...
Recent breakthroughs in autism spectrum disorder (ASD) research focus on precision medicine approaches, leveraging genetic technologies to identify risk genes and develop personalized therapies. Neuroimaging studies are also helping understand brain structure and function across the lifespan.
A small study found distinct patterns of regulatory tags in DNA from fathers' sperm linked to children's early signs of autism. The presence or absence of these tags was statistically related to Autism Observation Scale for Infants scores, suggesting a potential contribution to the condition.
A new study finds that healthcare providers' passive and reassuring responses to parental concerns about early development delays ASD diagnoses by up to 2 years. Early identification of ASD is crucial for improved long-term developmental outcomes.
A large study found a significant association between intrauterine exposure to gestational diabetes and an increased risk of autism spectrum disorders in offspring. Maternal pre-existing type 2 diabetes was not significantly associated with this risk.
A study from the University of Missouri found that violent video games do not affect adults with autism spectrum disorder differently than typically developing adults. Over 100 participants, half with autism and half without, showed similar aggression levels after playing violent or nonviolent games for 15 minutes.
A new Kaiser Permanente study found that children whose mothers developed gestational diabetes by the 26th week of pregnancy had a 63% increased risk of being diagnosed with an autism spectrum disorder. The study also found that early screening for autism in children of women with gestational diabetes may be warranted.
Researchers used fMRI to analyze brain activity in response to speech in ASD toddlers, finding distinct neural substrates for good and poor language outcomes. The study's findings may lead to more individualized treatments for the heterogeneous condition.
Researchers found that neural activity in language-sensitive brain regions in infants and toddlers with ASD was similar to normal in those who developed good language ability, but nearly absent in those with poor outcomes. The study's results have the potential to predict later language outcome by early childhood.
A new study suggests that non-violent video games with storytelling can have prosocial benefits, improving emotional intelligence and social skills. The research found that immersive gaming experiences foster theory of mind and empathy, which can be helpful in treating disorders like autism.
A study by San Diego State University scientists found that children with autism have overdeveloped connections between the cerebral cortex and cerebellum, affecting brain function. This early development leads to muscle in on brain real estate for higher cognitive functions.
Researchers at Scripps Research Institute aim to identify biomarkers for accelerated drug development of disorders including autism spectrum disorder, epilepsy, and intellectual disability. By validating biomarkers in mice, they hope to create tools and methods for developing new therapeutics.
Scientists have developed a mouse model that lacks the nSR100 gene, which regulates microexon splicing. This process is essential for protein production and brain function. The study found defects in neuron formation and wiring, similar to those found in people with autism and schizophrenia.
Researchers have found that rats can link cause and effect, form causal beliefs, and make rational inferences about their actions. These findings have implications for understanding human reasoning, particularly in older adults, and could inform clinical treatments for neurodegenerative diseases.
A large longitudinal survey of Norwegian mothers found that children with autism spectrum disorder were two-and-a-half times more likely to have persistent gastrointestinal (GI) symptoms than children with typical development. The study also found that these symptoms appeared in infancy and persisted through age 3.
A study found that children with autism spectrum disorder were more likely to experience gastrointestinal symptoms, such as constipation and diarrhea, and food allergies/intolerances than their typical development peers. Mothers of children with ASD also reported more persistent GI symptoms in the first three years of life.
A Johns Hopkins-led team of researchers has identified a rare genetic cause of autism, which may also be linked to other complex genetic conditions. The study used a novel approach that focused on families severely affected by autism to pinpoint the CTNND2 gene as a potential culprit.
A child with autism improved dramatically while taking an antibiotic for strep throat, prompting a quest by the parent to understand the phenomenon. The collaboration led to a scientific conference and special issue in a scientific journal featuring articles on the microbiome's involvement in autism.