Articles tagged with Cervical Cancer
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Scientists have created new fluorescent chemical compounds for photodynamic therapy of cancerous tumors, which can stain affected tissues and destroy tumor cells without harm to healthy ones. The compound containing pyrene shows the highest fluorescent and anticancer activity.
A national survey study found that colorectal cancer screening increased via stool testing while colonoscopy decreased during the pandemic. Breast and cervical cancer screenings also saw modest declines.
A study of 1.3 million women in England found that screening every five years is as effective as three-year intervals for those with a negative HPV screen, and may even prevent more cancers. The study provides reassurance to women aged 24-49 who test negative for HPV.
A recent study reveals that sexual minority individuals are less likely to undergo cervical cancer screening, with Hispanic individuals facing the most significant disparities. The analysis of 2015–2018 data from the National Health Interview Survey found that white sexual minority participants and Hispanic sexual minority participants...
Researchers have developed mini organs that replicate the cervical tissue, allowing for the study of normal physiology, disease development, and infectious processes. The creation of these mini organs, known as organoids, offers new opportunities for personalized medicine, finding new active substances, and modeling diseases.
Cancer incidence is projected to double in SSA by 2040, with 1.4 million cases per year expected without rapid interventions. Women are more affected by cancer than men in the region, with breast and cervical cancers among the most common types.
Canada's cancer rates are declining overall, but new cases and deaths are on the rise due to an aging population and growing numbers. Despite this, efforts in cancer prevention, screening, early detection, and treatment have led to improved survival rates for those diagnosed with cancer.
A new study published in the Journal of Medical Screening found that over half of eligible women (51.4%) prefer self-sampling for cervical cancer screening, as it addresses concerns about embarrassment and provides more flexibility. The study also suggests that many regular screeners may switch to self-sampling if offered the option.
The program aims to increase trained cancer researchers in Tanzania and prepare them for HIV-associated cancer diagnostics, genomics, and therapy. It will focus on molecular detection, epidemiology, and biology of common HIV-associated malignancies.
A recent study by Cathy Bradley found that Medicaid patients with continuous coverage have better cancer survival rates compared to those without. Conversely, screening programs for low-income women may not be as effective as general insurance coverage.
A randomized controlled trial of 2,275 women in Kenya found a single dose of the human papillomavirus (HPV) vaccine to be highly effective. The study results support the adoption of a single-dose HPV vaccination, which could increase accessibility in low- and middle-income countries.
Researchers found that changes in viral communities may enable persistent HPV infection and progression to cancer, associated with bacterial composition and inflammation. Low Lactobacillus abundance and bacteriophage presence were also linked to increased risk.
A new study reveals that the COVID-19 pandemic has led to significant declines in cancer screening rates across the US, particularly for colorectal, cervical, breast, and lung cancers. The American Cancer Society's National Consortium has announced nine recommendations to increase cancer screening rates and improve quality care.
Researchers found that adding atezolizumab to chemoradiation treatment was safe and demonstrated immune activation in women with node-positive, locally advanced cervical cancer. The study also showed increased peripheral blood T-cell receptor clonal expansion and tumor-associated T-cell clones.
A new phenomenon was discovered where increased pressure leads to a sudden burst of rapid and coordinated cellular motion, spraying outwards from the tumour. This fluid-like pushing mechanism can kill cancer cells but also enables them to survive and multiply in new environments.
A new study found that cervical cancer incidence is increasing in low-income US counties, while plateauing in high-income counties. The study analyzed data from 2000 to 2018 and estimated trends by county-level household income and smoking prevalence.
A new study found significant increases in HPV-associated anal, oropharyngeal, and vulvar cancer in the US, particularly in low-income counties with high smoking rates. The increases were slower in higher-income areas.
The Cancer Prevention & Research Institute of Texas has awarded a grant extension to Dr. Rakhshanda Rahman, allowing her to provide no-cost mammograms and Pap smears to underinsured and uninsured women in the Permian Basin. The program aims to address high cervical cancer incidence and mortality rates in West Texas.
Researchers have found that HPV and Chlamydia pathogens work together to reprogram cells, leading to cancer. The study used 3D organoids to investigate the interactions between the pathogens and tissues affected by disease.
New studies from Michigan Medicine researchers aim to remove financial barriers for patients who receive abnormal test results, enabling them to complete the diagnostic process. The findings suggest that removing cost barriers could save lives by increasing screening uptake, particularly among women and underserved populations.
Results from the Phase III EMPOWER trial demonstrate the efficacy of PD-1 inhibitor cemiplimab in improving overall survival for women with recurrent and/or metastatic cervical cancer. The study showed a 31% lower risk of death in patients receiving cemiplimab compared to chemotherapy.
Women treated for cervical neoplasia grade 3 show declining risks of preterm birth, neonatal sepsis, and infant death after treatment. The study suggests that these high-risk pregnancies should be managed with careful consideration.
A study found that risks of preterm birth, infant sepsis, and other adverse outcomes associated with CIN-3 treatment have decreased over time. Pregnancies after CIN-3 treatment should be managed as 'high risk' to reduce these risks.
Ovarian cancer death rates are predicted to decrease by 17% in the UK and 7% in EU countries in 2022. The main contributor is the long-term use of oral contraceptives, reducing the risk by 40%. Other factors include improved diagnosis, treatment, and advancements in treatments for other cancers.
Rates of cervical cancer screening have dropped in the US, with significant disparities found across sociodemographic groups. The study highlights the need for targeted campaigns to address lack of knowledge as the primary reason for not receiving timely screenings.
A nationwide study found decreased cervical cancer incidence and death rates among women and girls aged 15-24 after HPV vaccine introduction. The decline was more pronounced in the younger age group compared to those aged 25-29 and 30-39, suggesting a potential association with vaccination.
The study found that cervical cancer rates in NYC neighborhoods with low socioeconomic status are significantly higher than those with high socioeconomic status, highlighting the need for neighborhood-level interventions to increase access to preventive services.
Research conducted by Brigham and Women's Hospital found that cervical cancer rates are significantly higher in low SES neighborhoods of New York City. The study analyzed data from two databases and calculated a 73 percent greater risk of cervical cancer in these neighborhoods compared to high-SES areas.
A population-based study found a significant association between neighborhood socioeconomic inequality and cervical cancer rates in NYC. The study revealed that low-socioeconomic status neighborhoods had higher cervical cancer incidence rates compared to higher-socioeconomic status neighborhoods.
A randomized controlled trial in Kenya showed a single dose of the human papillomavirus (HPV) vaccine was highly effective at 18 months, with efficacy comparable to multiple doses. The findings could hasten vaccinations and bring renewed energy to global efforts to eliminate cervical cancer.
A new study published in The Lancet confirms that HPV vaccination has led to a significant reduction in cervical cancer rates in England. Women who were vaccinated between the ages of 12-13 had an 87% lower incidence of cervical cancer compared to previous generations.
A new study improves AI diagnoses by penalizing algorithms for false negatives, which can be more urgent than accuracy. Researchers achieved significant improvements in precision and recall for chronic kidney disease and other conditions using cost sensitivity techniques.
A study by University of New Mexico researchers found that 65% of women with a normal prior co-test had undergone re-screening within three years, far more often than recommended. Meanwhile, some women were not re-tested for over five years after a negative co-test or cytology alone, increasing their risk for poor outcomes.
A pilot program providing tailored cervical cancer screening for trans men and nonbinary people was well-received, with 100% satisfaction rates. The program aimed to address barriers such as dysphoria and stigma, and could serve as a model for similar programs.
A recent study found that HPV vaccine hesitancy has either stabilized or increased in some ethnic and age groups, highlighting the need for targeted campaigns to encourage hesitant families. The study also identified several reasons why parents hesitate to vaccinate their children with the HPV vaccine.
New studies show that patients with abnormal screening results may face significant out-of-pocket costs for follow-up tests, potentially delaying care. For women, colposcopy costs rose sharply over 13 years, with some facing bills of nearly $1,000. Lung cancer screening CT scans also led to high costs for invasive procedures.
The KEYNOTE-826 study found that adding immunotherapy to standard first-line treatment increases overall survival by eight months for patients with recurrent, persistent or metastatic cervical cancer. The addition of pembrolizumab to chemotherapy also reduced the risk of death and disease progression by 33%.
Breast and colorectal cancer screening rates increased following the introduction of national quality indicators, with greater reductions in socioeconomic disparities. Cervical cancer screening rates remained unchanged due to its exclusion from initial quality indicators.
A predictive model estimated that cervical cancer may be eliminated in the US by 2030 in low-poverty areas, but not until 2044 in high-poverty areas. Health care disparities are a major contributor to these disparities, including lower vaccination rates and higher prevalence of cancer-causing HPV types.
Researchers at SMU found that decreasing TIGAR protein levels in cervical cancer cells makes them more responsive to chemotherapy drugs at low doses. This discovery offers a potential new treatment approach for HPV-induced cervical cancer with fewer side effects.
Researchers found changes in erythrocyte morphology and nanoparticles on cell surfaces during radiation therapy, which may indicate treatment effectiveness or prognosis. The study suggests that analyzing these changes could lead to the development of a diagnostic method for assessing RT efficacy.
Researchers developed a topical fluorescent imaging agent targeting PARP1 enzyme in cervical cancer cells, enabling real-time detection with handheld microscopes. This non-invasive method could revolutionize cervical cancer screenings and biopsies, especially in low-resource areas.
The ASCCP Task Force supports the ACS's 2020 cervical cancer screening guidelines, which recommend primary HPV testing. During the transition to primary HPV screening, the Task Force endorses any cervical cancer screening approach, including co-testing and cervical cytology alone.
The study found a decline in women's use of preventive health services, including sexually transmitted infection screenings and breast cancer screenings. Women also experienced reduced access to contraceptives from pharmacies during the pandemic.
A recent study found that fewer than one in three women aged 64 to 66 met the criteria to discontinue cervical cancer screening. The majority of women in this age group may be at risk for cervical cancer due to inadequate screening or preexisting high-risk conditions.
A study by Monash University found a significant reduction in all four HPV genotypes in gay/bisexual men after implementing the school-based HPV vaccination program. The results suggest that male vaccination may lead to a potential reduction in anal cancer among gay and bisexual men in Australia.
A recent study found that only 19% of women in sub-Saharan Africa underwent cervical cancer screenings between 2011 and 2018. The rates varied greatly by country, with some countries having nearly 46% of women screened versus less than 1%. Increasing screenings is crucial to detect the disease early and improve treatment outcomes.
A new study found a substantial decrease in minimally invasive surgery use for cervical cancer after the publication of a major study in 2018. The study assessed 2,437 patients and showed that surgeons changed their methods, but still saw room for improvement at non-academic medical centers.
A recent study found that only 16% of male teenagers received the HPV vaccine, highlighting a significant gap in vaccination rates. The vaccine is essential for preventing oropharyngeal cancer, which affects 80% of male patients diagnosed with this condition.
Researchers have created the first patient-derived organoid model for cervical cancer, allowing them to study human papillomavirus (HPV) and its impact on cervical tissue. The model's success holds promise for advancing research into cervical biology and associated diseases.
Researchers found that brachytherapy can proceed without delay or antibiotics in cervical cancer patients with uterine perforations, reducing treatment complications. The study suggests this approach could lead to a new standard of care and improved survival rates for these patients.
A study found that adequate levels of five antioxidants may reduce infection with high-risk human papillomavirus (HPV) strains associated with cervical cancer. Lower levels of serum albumin and four dietary antioxidants were linked to a higher risk of HPV infection, suggesting a potential nutritional strategy for prevention.
Emerging technologies can screen for cervical cancer better than Pap smears, especially in places with limited access to healthcare. Advanced nanotechnology and computer learning are helping develop HPV screening that takes the guesswork out of precancer tests.
A study of over 150,000 European women has identified PAX8, CLPTM1L, and HLA region gene variants associated with an increased risk of developing cervical cancer. The findings open avenues for personalized screening approaches or targeted treatments.
The conference explored updates to NCCN Clinical Practice Guidelines, new research, and strategies for preventing HPV-associated cancers. Experts discussed ways to improve racial equity in cancer care, including reducing disparities and promoting guideline-adherent care.
A new AI-powered screening tool has been developed to detect precursors to cervical cancer in women, particularly in low-income countries where access to skilled pathologists and advanced equipment is limited. The method uses mobile digital microscopy and achieves a sensitivity of 96-100% in identifying patients with precancerous lesions.
Research from Michigan State University highlights the racial disparity gap in cervical cancer information and follow-up, citing poor provider-patient communication as a key factor. The study suggests that improving education and using digital channels like text messages can help bridge this gap.
A new study found that vaccinating adults age 26 and older against HPV may not provide significant health benefits, due to high costs and lower vaccine efficacy in older individuals. Cervical cancer screening remains an effective way to protect women from cervical cancer.
A special issue of Preventive Medicine outlines courses of action to eliminate cervical cancer through HPV vaccination, screening, and treatment. The WHO strategy aims for 90% HPV vaccination coverage, 70% screening coverage, and 90% access to treatment by 2030.
The journal's publication outlines targets for HPV vaccination, screening and treatment to achieve 90%, 70% and 90% coverage respectively. The World Health Organization strategy aims to eliminate cervical cancer globally by 2030.