Articles tagged with Sexually Transmitted Diseases
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Researchers examine translational studies on peripheral surrogates of tumor burden, including circulating tumor DNA, miRNA, and HPV-specific antibodies, to inform chemotherapy and immunotherapy strategies. These biomarkers show promise as prognostic and predictive markers of response to treatment.
Researchers found a novel region in the genome associated with spontaneous control of HIV in populations of African ancestries. CHD1L, a protein involved in DNA repair, shows genetic variation specific to these populations and limits HIV replication in white blood cells.
A Kenya-based study found that menstrual cups reduced the risk of bacterial vaginosis and improved vaginal microbiome in teenage girls. The study, funded by the National Institutes of Health, followed 436 Kenyan secondary school girls and tested for infections every six months.
Researchers have found that microglial cells in the brain can serve as a stable viral reservoir for latent HIV. This discovery provides new insights into how to target and eradicate the virus, particularly in the brain or peripheral blood.
Despite the decline in most services, FQHCs reported an increase in patient visits for substance use disorder, depression, anxiety, and sexually transmitted infections. Quality-of-care measures also plummeted, with only one measure returning to pre-pandemic levels.
A new finger-prick test for Trichomonas vaginalis has been developed by Washington State University researcher John Alderete. The test detects an antibody specific to the organism and provides rapid, affordable results, making it a potential game-changer in the fight against this prevalent but neglected STI.
Scientists detected the emergence of extensively drug-resistant (XDR) Shigella sonnei strains in France, primarily among men who have sex with men. XDR isolates are resistant to virtually all antibiotics, requiring complex treatment and hospitalization.
A global study aims to better understand the burden of Human papillomavirus (HPV) among girls and women in low- and lower middle-income countries. The study will inform effective strategies to prevent infection and introduce HPV vaccine into national programs, protecting the health of girls and women and reducing rates of cervical cancer.
A fast-dissolving insert containing TAF and EVG was found safe and effective in preventing HIV transmission through anal sex. The study delivered high levels of the drugs to rectal tissue and fluid, with potential protection for up to three days after use.
Researchers found that doxycycline postexposure prophylaxis did not prevent chlamydia or gonorrhea among cisgender women in a clinical trial. The lack of efficacy was attributed to differences in anatomy and antibiotic resistance.
The US Preventive Services Task Force (USPSTF) recommends against routine serologic screening for genital herpes simplex virus infection, even in symptomatic individuals. The lifelong nature of HSV infection means there is no cure, but antiviral medications can provide clinical benefits to those experiencing symptoms.
A major international trial found that patients with 'discordant' HPV test results, where the two types of tests show different results, have significantly worse outcomes than those who tested negative in both tests. The study also found that smoking status is a significant factor, with smokers at higher risk of worse outcomes.
A new study reveals that all 50 US states now allow minors to consent independently to some STI/HIV services, but confidentiality protections are rare and vary significantly. The laws remain complex, with gaps in coverage for prevention services like the HPV vaccine and PrEP.
There were significant increases in HPV vaccine administration among commercially insured adults aged 27 to 45 following the Advisory Committee on Immunization Practices' recommendation change in 2019. This trend is attributed to shared decision-making between patients and clinicians.
A systematic review of national clinical practice guidelines in Europe found that fewer than half include HIV testing recommendations for patients with medical conditions indicating HIV infection. This omission hinders efforts to stop the spread of HIV through timely diagnosis, affecting the lives of people living with HIV.
A study led by Dr. Ashish Deshmukh finds a significant increase in anal cancer incidence among women and men over 50 years old in the Midwestern and Southeastern states, with HPV infections and smoking identified as key risk factors.
A recent study published in JAMA Network Open found that human papillomavirus (HPV) vaccination effectiveness differs significantly depending on the age at which it is administered. The researchers analyzed self-reported data from female participants and discovered that HPV vaccination is most effective when administered earlier in life.
The USPSTF recommends screening for syphilis in asymptomatic, nonpregnant individuals who have ever been sexually active. Syphilis cases increased from a record low in 2000 to 11.9 cases per 100,000 population in 2019.
Researchers at Georgia State University have discovered a way to prevent and treat gonorrhea by generating a mutation in a key molecule. The study found that inhibiting the bacterial pathogen's ability to hijack human immunity proteins could block gonorrhea infection.
A synthetic prophylactic gel developed at KTH Royal Institute of Technology has shown promising results in lab tests, with a 70% effectiveness rate against HIV and an 80% effectiveness rate against herpes.
A review of evidence found that 2-3% of monkeypox patients experienced severe complications such as seizure or encephalitis. Mood disorders like depression and anxiety were also common among infected individuals.
A new study found that HIV-1 Tat expression accelerates age-related diseases in male mice by disrupting neuroendocrine function. Researchers discovered that Tat alters steroid hormone levels, leading to anxiety-like behavior, cognitive errors, and reduced grip strength.
Researchers developed a nomogram to predict anal cancer risk in persons with HIV infection, highlighting increased risk among those living with the virus. The model estimates quantitative risk based on patient characteristics, informing screening decisions.
Scientists detect a highly resistant strain of Neisseria gonorrhoeae in Austria, causing treatment failure with current antibiotics. The discovery highlights the urgent need for enhanced antimicrobial surveillance and development of novel treatments to combat this growing public health concern.
Meningitis vaccines may offer significant protection against gonorrhoea, reducing cases of the infection considerably. Studies suggest a two-dose course of 4CMenB provides 40% protection against gonorrhoea in young adults and adolescents.
A recent study found that child abuse investigations by Child Protective Services (CPS) do not necessarily prevent poor sexual health outcomes in adolescent girls. In fact, the researchers discovered that girls who underwent investigation were more likely to experience adverse sexual health outcomes, including STIs and pregnancy, befor...
The WHO European Region saw a decrease in reported cases of syphilis, gonorrhoea and chlamydia, but data availability varies widely among non-EU/EEA countries. Georgia had the highest syphilis case rate, while EU/EEA countries had lower rates.
Researchers at UC San Diego found a steep rise in HIV incidence among people who inject drugs in Tijuana, driven by undiminished drug tourism. The rate of infection is 11 times higher than in San Diego residents who do not cross the border.
A recent study published in Frontiers in Cellular and Infection Microbiology found a significant increase in sexually transmitted infections (STIs) among girls and young women in western Kenya, coinciding with the COVID-19 pandemic. Researchers attribute this rise to increased stress-related changes in the vaginal microbiome.
New research from the University of Georgia reveals that crisis pregnancy centers offering STI and HIV services are not meeting quality care standards. Many CPCs fail to offer comprehensive testing, treatment, or referrals, despite advertising as medical facilities.
Researchers found a link between HPV genotype 16/18 infection in the first and third trimesters and an increased risk of preterm birth. The study highlights the importance of prenatal screening for HPV to inform pregnancy management.
The USPSTF advises regular screening for chlamydia and gonorrhea in young women due to their high incidence rates. Screening is also recommended for women at increased risk, with current evidence insufficient to support recommendations for men.
A study at the University of Liverpool found that disease risk in ladybirds cannot be predicted without understanding disease dynamics at a small geographical scale. The researchers discovered that differences in mating rates across habitats, driven by food supply, contributed to varying disease outbreak sites.