A new study found that tirzepatide can produce sustained weight loss of up to 31% in adults with overweight or obesity without diabetes, regardless of age or BMI. The study also identified patterns of weight loss trajectories and found that females and those without obesity-related complications may be more responsive to the medication.
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A large majority of older Americans believe health insurance – including Medicare – should cover anti-obesity medications. Nearly 37% of respondents met the criteria for overweight and 36% for obesity. Medicare currently covers a drug used for weight management but only in people with diabetes or a history of heart attack or stroke.
Most older U.S. adults support Medicare covering weight management medications, particularly those with a BMI of 30 or greater. The survey also found that more than half of participants were interested in using these medications to manage their weight.
New research suggests that maintaining a healthy weight throughout life and losing weight later in life may reduce the risk of kidney cancer. Higher BMI at various ages across adulthood was associated with increased risks of developing different types of kidney cancer, including renal cell carcinoma, papillary RCC, and chromophobe RCC.
A study published in The Journal of the National Cancer Institute found that waist circumference is a stronger risk marker than body mass index (BMI) for obesity-related cancers in men. However, this association was not observed in women.
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A new study found that new-onset type 2 diabetes is associated with an increased risk of certain obesity-related cancers, such as bowel and pancreatic cancer. The study analyzed data from the UK Biobank and found a 48% increased risk in men and a 24% increased risk in women for overall obesity-related cancers.
Research suggests that having an overweight or obesity trajectory during childhood is associated with a higher risk of chronic obstructive pulmonary disease (COPD) in adulthood. The study found that women with above-average childhood BMI trajectories had a 26% higher risk, while those with an obesity BMI trajectory had a 65% higher risk.
Research suggests that people with obesity experience a redistribution of their body compartments, such as increased fat trunk accumulation and lower muscle mass, particularly in extremities, as they age. This shift occurs without significant changes in BMI, making it a less useful tool for assessing weight status.
A recent study published in Heart journal found that extreme weight fluctuations significantly increase the risk of death among obese individuals with cardiovascular disease. Both weight loss and gain above 10kg raise mortality risk, highlighting the importance of maintaining a stable weight even within the obese range.
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A new study found that waist-to-height ratio is more accurate than BMI in estimating body fat in children. The study included 7,600 children and found that 64% of those classified as BMI-overweight had normal fat according to waist-to-height ratio.
A responsive parenting intervention demonstrated a significant reduction in child weight outcomes from age 3 to 9 compared to a control group. The intervention's benefits were most pronounced among female participants, and its long-term effects may be sustained with a life-course approach.
A new study found that the proportion of visceral fat, rather than the absolute amount, is a stronger predictor of high triglyceride levels and inflammation. Lowering visceral fat proportion during weight loss can lead to better metabolic health outcomes.
A third of children and adolescents will be overweight or obese within the next 25 years, according to a new study. The global obesity rate for those between 5-24 years old tripled from 1990 to 2021, rising by 244 per cent to 174 million.
A major new analysis predicts that over half the world's adult population (3.8 billion) and a third of all children and adolescents (746 million) will be living with overweight or obesity by 2050. The study forecasts a substantial rise in obesity among young people globally, with an additional 186 million cases predicted by 2050.
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A University of Turku study reveals that mothers' weight and diet during pregnancy influence their child's motor skills up to age 5-6. Children of overweight or obese mothers are almost three times more likely to develop a developmental coordination disorder, highlighting the importance of healthy prenatal nutrition.
A long-term study found that Roux-en-Y gastric bypass outperforms sleeve gastrectomy in treating obesity, with patients losing more excess body mass index. The Swiss Multicenter Bypass or Sleeve Study demonstrated the superiority of Roux-en-Y gastric bypass over sleeve gastrectomy for patient weight loss.
A study by University of Gothenburg researchers found that consuming sulforaphane from broccoli sprouts improved blood sugar levels in people with prediabetes. The compound had a significant effect on fasting blood sugar levels, particularly in those with certain pathophysiological and microbiome characteristics.
Researchers identified two new patterns in childhood BMI development, differing from the traditional 'Type 1' trajectory. Type 2 and Type 3 trajectories have distinct profiles, with Type 2 showing a steeper rise and fall before and after infancy peak, while Type 3 has more irregular peaks and troughs.
The American Heart Association and NFL Alumni Association collaborate to promote healthy lifestyles through Life's Essential 8, which includes four indicators of cardiovascular health and four behavioral/lifestyle factors. By following these steps, adults can lower their risk of heart disease, stroke, and other cardiovascular conditions.
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Adolescents who perceive themselves as overweight face triple the risk of self-harm compared to those who do not, regardless of objective weight. The study also highlights the critical role of schools and communities in creating supportive environments.
A study of older adults found that decline in body mass index, waist circumference, and high-density lipoprotein (HDL) occurred up to a decade before dementia diagnosis. These cardiometabolic changes may provide insights into the potential for early monitoring and intervention.
A recent study published in Plastic and Reconstructive Surgery found that breast reduction surgery can lead to weight gain in adolescents and young women, particularly those who were at a healthy body mass index (BMI) before surgery. The study suggests that these patients should be targeted for healthy lifestyle changes to prevent weig...
The American Heart Association's 2025 statistics report shows an increase of over 10,000 cardiovascular disease-related deaths in the US, with a slight decrease in age-adjusted death rates. Rising kidney disease, hypertension, and obesity are contributing to these trends.
A cohort study found city-level sugar-sweetened beverage taxes associated with reduced mean body mass index (BMI) among adults. These associations were seen in demographic subgroups, including young adults who consumed the most SSBs.
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A retrospective cohort study of 44,000 individuals found associations between baseline fasting glucose levels, age, sex, and body mass index with the development of diabetes. The study highlights individual variation in diabetes risk according to commonly measured clinical variables, suggesting potential for targeted interventions.
A new study found disparities in access to semaglutide based on insurance plan, job industry, sex, and other factors. Individuals with female identities, preferred provider organization coverage, and antidepressant use were more likely to start taking semaglutide compared to males or those with certain employment industries.
Research published in the European Heart Journal found that people with high amounts of intermuscular fat are more likely to develop coronary microvascular dysfunction and future serious heart disease. The study's lead author suggests that existing measures of obesity may not be accurate for all individuals, particularly women.
A new Cochrane review found that calorie labelling in supermarkets, restaurants, and other food outlets leads to a small reduction in the calories people select and purchase. The average reduction was 1.8%, equating to around two almonds per 600-calorie meal.
Exposure to air pollution during the three months before pregnancy is associated with higher childhood obesity risk up to two years after birth. The study found that women with higher levels of PM2.5 and PM10 had children with a higher BMI and related obesity risk factors.
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The Lancet Commission on Clinical Obesity proposes a new model for diagnosing clinical obesity based on objective measures of illness at the individual level. The proposal aims to settle the ongoing dispute around the idea of obesity as a disease, providing a medically coherent framework for diagnosis.
The global Commission recommends diagnosing obesity based on excess body fat measures and objective signs of illness, shifting from BMI-based definition. This approach aims to provide personalized care for individuals with clinical and pre-clinical obesity, facilitating fair allocation of healthcare resources.
A new study found that exposure to high aircraft noise levels can lead to stiffer and thicker heart muscles, increasing the risk of poor heart function and major cardiac events. People exposed to night-time aircraft noise were particularly at risk, with increased risks of heart attacks, life-threatening rhythms, and strokes.
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Research found that infants given milk cereal drinks after six months old experience early rapid weight gain but not higher body mass index or waist-to-height ratio. Early rapid weight gain is predictive of later adiposity, regardless of supplement consumption.
A new study found significant disparities in the use of obesity-management medications among different racial and ethnic groups. People of Asian, Black, and Hispanic descent were significantly less likely to use these medications compared to whites, even after adjusting for income, education, health insurance coverage, and clinical need.
Researchers from the University of Granada and the Public Health Agency of Canada identified the most important physical fitness tests for children and adolescents, with a degree of scientific agreement exceeding 85%. The top tests include the 20-meter shuttle run test, handgrip strength test, standing long jump test, and body mass index.
Adult obesity trends in the US have declined for the first time in more than a decade, according to recent data. The South region experienced the largest decreases in body mass index and obesity prevalence, despite also facing high COVID-19 mortality rates among obese individuals.
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Consuming 20-30% of daily energy at breakfast is associated with lower body mass index, smaller waist circumference, significantly lower triglyceride levels, and higher HDL cholesterol. A high-quality breakfast with proper balance of proteins, fats, fiber, and nutrients also contributes to reducing cardiovascular risk factors.
Population-level improvements in total cholesterol and triglyceride levels slowed, while adverse trends in glucose levels accelerated in more recent US birth cohorts. Public health initiatives targeting antecedent health behaviors are needed to improve cardiometabolic health across generations.
Researchers found that women who had both ovaries surgically removed before age 50 are at high risk of late-life Alzheimer's disease, with a fourfold increase in risk linked to the APOE4 allele. Hormone therapy reduces this risk by half in these women.
A recent study found that excessive sitting significantly harms young adults, increasing the risk of heart disease and obesity. Reducing sitting time improves health outcomes, while doubling recommended exercise hours is more effective at lowering health risks.
A study published at the Radiological Society of North America annual meeting found that ultra-processed food intake is associated with higher amounts of intramuscular fat in thigh muscles. This increase in fat can lead to knee osteoarthritis, a condition affecting millions worldwide.
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Researchers have discovered a specific type of body fat linked to abnormal proteins in the brain that are hallmarks of Alzheimer's disease. Higher levels of visceral fat were found to be associated with increased amyloid accumulation and higher PET levels of hallmark pathologic proteins.
A cross-sectional study found significant increases in postpartum depression diagnosis among all racial and ethnic groups and body mass index categories over the past decade. The persistently high rates underscore the need for preventative interventions to mitigate PPD's impact on maternal and child health.
The large cohort study identified common pregnancy complications, such as premature rupture of membranes and gestational diabetes mellitus, affecting 18.29% and 16.74% of participants, respectively. High-risk groups were also identified, including women with assisted reproductive technology and those aged 35 and older.
The international SUMMIT trial found tirzepatide lowered the risk of worsening heart failure events and cardiovascular death in obese adults with preserved ejection fraction. Participants experienced improved health status, physical function, and exercise tolerance compared to placebo.
New research links ancient Jomon hunter-gatherer genetic signature to higher body mass index (BMI) among individuals in modern Japan. The study found strong support for the tripartite ancestry model, suggesting a significant influence of Jomon ancestry on BMI across populations.
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Researchers at the University of Nottingham have discovered that GLP-1 receptor agonists may be effective in reducing alcohol consumption. The study suggests that this type of diabetes medication could potentially treat excessive alcohol use and lead to a reduction in alcohol-related deaths.
A new study from deCODE genetics/Amgen highlights the importance of Body Mass Index (BMI) in disease pathology, suggesting that reducing BMI could lower the risk of various diseases. For some conditions like fatty liver disease and glucose intolerance, the genetic link to disease disappears when BMI is taken into account.
A recent study published in Topics in Stroke Rehabilitation found that slightly overweight stroke survivors (BMI 22.1-27.5 kg/m²) have a lower risk of sustaining disabilities compared to those with normal weight. The research suggests that a higher-than-normal BMI may be beneficial for recovering from a stroke with less disability.
Research published in PLOS ONE reveals that prolonged sitting can boost the risk of heart disease and accelerate aging in young adults. The study found that even moderate exercise may not be enough to counteract the negative impacts of prolonged sitting.
A new NIH study found exposure to organophosphate esters (OPEs) during pregnancy may affect childhood obesity risk. Children exposed to higher levels of certain OPEs had a greater or lower risk of obesity compared to those with lower exposure.
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Research from Karolinska Institutet finds that abnormal BMI in children can lead to impaired lung function, but normalizing BMI before adulthood may offset this. The study, which followed over 4,000 children, also found a correlation between low BMI and reduced lung growth.
Elevated body mass index (BMI) was associated with a significantly increased post-acute sequelae of SARS-CoV-2 infection risk. The study highlights the need for targeted care to prevent chronic conditions in at-risk children and young adults.
Research from Lancaster University found that restricting new fast-food outlets led to fewer overweight and obese children in Gateshead, England. The policy resulted in a statistically significant reduction of 4.80% in childhood obesity prevalence in deprived areas.
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A large cohort study found that mothers with eating disorders were more likely to have children with psychiatric disorders, while those with pre-pregnancy BMI outside the normal range also showed an increased risk. The findings suggest that clinicians should consider these factors when preventing offspring mental illness.
The EAT2 study, led by Dr. Ursula White, investigates the lasting health effects of short-term weight gain and loss on fat tissue and overall health. Participants will undergo a dietary intervention program followed by an eight-week weight loss treatment.
A recent study analyzing data from the ANCORS-YW study found that overweight and obese women in this region are at a higher risk of hypertension and cardiovascular disease. Researchers recommend tailored preventive strategies, including lifestyle modification programs and socioeconomic support, to address this public health challenge.
A recent study published in The Lancet Public Health found that body weight is a significant factor in pregnancy complications, affecting women born in different countries. Researchers estimated that approximately half of all cases of gestational diabetes could be prevented if all women were of normal weight during pregnancy.
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A recent study published in the International Journal of Behavioral Nutrition and Physical Activity suggests that extending overnight fasts and eating an early breakfast may be associated with a lower body mass index. The research, led by the Barcelona Institute for Global Health, involved over 7,000 volunteers who answered questionnai...
A study of 793 girls found significant variation in height growth after their first period, with most not reaching the expected 6-8 cm. Early onset of menstruation is linked to greater growth, while late onset is associated with shorter final height. Childhood BMI also plays a role in determining menarche age and subsequent growth.