A study published in JAMA Network Open found that body mass index (BMI) has a more complex relationship with mortality risk during cancer therapy than previously thought. For patients with advanced non-small cell lung cancer, higher BMI was associated with lower mortality when undergoing immunotherapy or conventional chemotherapy. Howe...
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A new study published in the New England Journal of Medicine found that liraglutide is safe and effective in reducing BMI by 7.4% in children aged 6 to under 12, as well as improving blood pressure and blood sugar control. The treatment was well-tolerated with no new safety concerns.
A Dutch study found that night owls are more likely to develop type 2 diabetes due to a disrupted circadian rhythm. Participants with late chronotypes had a 46% higher risk of T2D and increased body fat, including visceral and liver fat.
A new study found that higher BMI is associated with hospitalization for severe bacterial and viral infections. Conversely, mild hyperglycemia was not linked to increased risk of severe infections.
A study published in Annals of Internal Medicine found that approximately 61% of Medicare-eligible adults have a BMI of 27 or higher, making them eligible for semaglutide. However, the number of patients who will be eligible depends on how cardiovascular disease is defined, with narrow definitions resulting in only 3.6 million people b...
A KKH study found that exclusively breastfed women with high body mass index (BMI) lost more weight than those with a healthy BMI pre-pregnancy, with an average weight loss of 200 grammes. Women who practiced exclusive breastfeeding retained less postnatal weight compared to mixed feeding or formula feeding.
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A new study from Oregon Health & Science University reveals that people who are overweight and ignore their body's signals to sleep at night experience negative health consequences. The study found sex-specific differences in health impacts, with men having higher levels of belly fat and women having higher overall body fat percentage.
A smartphone healthcare application was found to be more effective for weight loss among non-walkers. Participants who did not have a walking habit at baseline were more likely to achieve successful weight loss with the app, possibly due to increased physical activity triggered by notifications.
Researchers found that Megamonas degrades intestinal myo-inositol, enhances lipid absorption, and contributes to obesity. The study suggests potential strategies for future obesity management by illustrating the bacterium's mechanism.
A study found that city-level sugar-sweetened beverage taxes are associated with lower body mass index percentile among youth. Policymakers may consider implementing such taxes to prevent or reduce youth overweight and obesity, ultimately reducing chronic disease risk, particularly among children under 12.
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Rates of hypertensive disorders of pregnancy increased from 6.1% to 8.5%, while related health conditions declined, according to a Canadian study. The growing population of high-risk obstetrical patients highlights the need for easily accessible specialized care.
Infants born to mothers with obesity are at higher risk of SUID due to a dose-dependent association between increasing maternal BMI and SUID risk. Research suggests that maternal obesity should be added to the list of known risk factors for SUID.
A nationwide study found a marked increase in new GLP-1RA prescriptions for obesity, particularly since 2020. Semaglutide was the most prescribed GLP-1RA, but prescriptions among those with obesity without type 2 diabetes spiked, worsening existing racial and ethnic disparities.
Researchers found that bowel movement frequency is linked to long-term health, with younger people, women, and those with lower BMI tending to have less frequent bowel movements. The study also showed associations between bowel movement frequency and chronic disease risk, mental health history, and gut microbiome composition.
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A new framework for diagnosing and managing obesity in adults proposes modernizing obesity diagnosis to take account of all the latest developments in the field. The authors recognize that BMI alone is insufficient as a diagnostic criterion and that body fat distribution has a substantial effect on health.
A recent study found that for every same increase of BMI, fat mass and type 2 diabetes risk are increased in taller people. The authors hypothesize that the cardiometabolic risk of a higher BMI may be underestimated in taller grown populations worldwide.
A new German study reveals widespread grading bias based on gender, ethnicity, social origin, and body size, with minority students and those with higher BMIs receiving lower grades. The study used data from over 14,000 ninth graders, showing that biases stack up against students with multiple intersectional identities.
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Research emphasizes the impact of parental factors on offspring's health outcomes. The study discovered a significant association between parents' weight status at 17 and their children's risk of obesity. This finding suggests that health issues can be inherited across generations, with parental characteristics playing a crucial role.
Research highlights need for prevention and treatment approaches for children with obesity born underweight, finding links between low birth weight and cardiometabolic disease risks. Visceral fat storage issues contribute to type 2 diabetes risk.
A cohort study of 10,634 participants reveals that childhood risk factors are associated with adult cardiovascular disease. The study highlights the importance of intervening in childhood to reduce the incidence of adult CVD, particularly for body mass index (BMI) and low-density lipoprotein cholesterol.
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A recent study has identified three subgroups of gestational diabetes with different treatment needs, enabling personalized therapy and reducing complications for mothers and children. The analysis used cluster methods and machine learning to analyze data from 2682 women with gestational diabetes.
The USPSTF recommends providing or referring children and adolescents with a high body mass index (BMI) to comprehensive behavioral interventions. Approximately 19.7% of US children aged 2-19 have a BMI at or above the 95th percentile, with higher prevalence among Hispanic/Latino, Native American/Alaska Native, and lower-income families.
Researchers have discovered a better way to identify those at high risk of potential heart attacks and strokes by adding genetic information to health checks. The study found that combining clinical risk scores with polygenic risk scores significantly improves identification rates, especially among younger people.
Research shows people with obesity are more sensitive to price when buying unhealthy foods, while those with normal weight are not. A 10% price hike on these categories can lead to a significant reduction in consumption, such as decreased frozen pizza purchases.
Research published in the Stroke journal found that teenage women who were overweight or obese had a higher risk of ischemic stroke before age 55. The study analyzed data from over 50 years and suggested that even temporary excess weight may have long-term health effects.
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Current medical training neglects to educate future doctors on how to encourage healthier eating habits and focuses on weight loss and BMI. Researchers advocate for small changes in medical education to address anti-obesity bias and promote cardiometabolic health, a stronger predictor of overall well-being.
A new study found that people exposed to higher levels of airplane noise were more likely to have a higher body mass index, an indicator for obesity that can lead to cardiometabolic diseases. The study highlights the role of environmental factors in shaping health outcomes.
Longitudinal study finds that higher baseline body mass index is associated with more depressive symptoms over time. Children's cognitive performance also declines as they enter adolescence, highlighting the importance of monitoring children with overweight or obesity for depression problems.
A comprehensive study found that living with obesity for 10 years or more significantly increases the risk of heart attacks and strokes. The research, published at ENDO 2024, analyzed data from over 109,000 participants and revealed a 25-60% increased risk in younger adults.
A study published in Andrology found that testosterone therapy significantly improves body composition in transgender men, with no long-term side effects. Researchers also discovered that higher doses of testosterone may lead to faster results.
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A study in Seattle found a small but significant reduction in body mass index (BMI) among children living in areas with a sweetened beverage tax compared to nontaxed areas. The results support the effectiveness of such taxes as a policy for improving children's BMI, building on existing US studies.
A recent study uses AI to analyze body composition in patients with lung cancer treated with immunotherapy, finding that changes in muscle mass and fat quality are important indicators of outcomes. The research provides a more nuanced understanding of the relationship between body composition and response to immunotherapy.
A recent study found that high cumulative BMI is associated with smaller brain volume, larger white matter lesions, and abnormal microstructural integrity in adults. Maintaining a healthy BMI below 26.2 kg/m² is suggested for better brain health.
A large register-based study found that young adults with low stress resilience are more likely to develop psoriasis later in life. The study, based on data from over 1.6 million Swedish men, showed a significant link between stress resilience and the risk of developing severe cases of psoriasis.
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A newly discovered connection between two brain regions may help regulate how much we eat, according to a Northwestern University study. The weaker the connection between these regions, the higher a person's BMI, suggesting that individuals with weak brain circuits may overeat even when full.
The Global Burden of Diseases study reveals a 49.4% increase in global disability-adjusted life years (DALYs) attributable to metabolism-related risk factors between 2000 and 2021. High blood pressure, high blood sugar, and high BMI are key contributors to poor health and early death.
A recent study found a significant association between body mass index (BMI) trajectories in middle adulthood and the risk of bone fractures in late adulthood. Maintaining a stable BMI throughout adulthood may reduce fracture risk later in life, according to researchers.
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A study found a dose-dependent association between adolescent body mass index and mental health, with the strongest link observed over time. The U-shaped relationship was consistent across sex and grade levels, highlighting the need for targeted interventions addressing body image and mental health.
A new study quantifies the impact of childhood obesity on long-term health and life expectancy. Childhood obesity was found to have a profound effect, with a child living with severe obesity at age 4 having a life expectancy of just 39 years. Weight loss can give back decades of life.
A new study suggests a lower BMI threshold of 27 kg/m² may be more appropriate than the existing WHO BMI threshold (30 kg/m²) for middle-aged and older adults. This could lead to improved health outcomes for millions of older adults, as body fat percentage is a more accurate indicator of obesity.
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Two studies based on the SELECT trial show semaglutide leads to sustained weight loss of 10% body weight and 7cm waist reduction after 4 years, regardless of starting weight or BMI. The medication also delivers cardiovascular benefits, with a lower risk of heart attack, stroke, or death.
Research suggests that the source of sugar, rather than the amount consumed, is crucial in developing obesity in children. A study found that children who got their sugar from unsweetened dairy products and fruit had a lower risk of becoming overweight or obese.
Researchers found that smokers skip meals more often, go longer without eating, and are more likely to snack between meals. They also tend to eat fewer sweet foods, but more fried foods, salt, and sugar than non-smokers.
Researchers discovered a link between high arm fat and low bone quality, particularly in the spine. Those with excess body fat, regardless of BMI, had lower bone quality and strength in their vertebrae.
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A study of over 7,500 US adults found that higher abdominal obesity, measured by waist circumference-to-height ratio, was associated with a higher risk of fecal incontinence. The researchers suggest that this may be due to increased intra-abdominal pressure and visceral fat-related inflammation.
A new study from Washington University School of Medicine found that nerve-stimulation treatment for obstructive sleep apnea is less effective for people with higher BMIs. The study analyzed data from 76 patients with BMIs of less than 35 and showed that the likelihood of successful treatment drops significantly as weight increases.
A Finnish study found that only 10% of newly diagnosed type 2 diabetics lost weight, while 3% gained weight, highlighting the challenges of achieving weight loss in these patients. The study also showed a strong association between weight gain and increased risk of microvascular and macrovascular complications.
Healthcare professionals express frustration with limited time and training to support families in addressing childhood obesity. They highlight the need for dedicated services and practical advice to help parents make healthy lifestyle changes.
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Research finds children's weight at age 8 and pubertal BMI changes independently predict high blood pressure in mid-life. Targeted initiatives for preventing childhood obesity may reduce disease burden.
Research suggests that for individuals under 65, maintaining a normal BMI is advisable, while those over 65 may benefit from moderate overweight. This study found a U-shaped relationship between BMI and cardiovascular death risk, with optimal BMI cut-off points varying by age group.
A new study from Karolinska Institutet found no increased health risks for mothers or children with weight gain below recommended guidelines for women with obesity classes 1 and 2. In contrast, weight loss was associated with reduced risk of adverse outcomes in women with class 3 obesity.
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A recent study found that eating fortified eggs had no adverse effect on blood cholesterol levels and may even have beneficial effects on cardiovascular health. Subgroup analyses revealed potential benefits among older adults and those with diabetes.
The study found that obesity rates have nearly tripled in adult men and doubled in women since 1990. The prevalence of malnutrition is now the most common form of malnutrition globally, affecting nearly 880 million adults and 160 million children. Obesity can lead to comorbidities like high blood pressure, heart disease, and diabetes.
A study published in JAMA Pediatrics found that the prevalence of overweight and obesity among 3- and 4-year-olds in Sweden has decreased after the pandemic. The researchers observed a reversal of unhealthy weight trends, indicating that an unhealthy weight status can be reversed.
A new study evaluates the use of tirzepatide in overweight/obese adults with type 1 diabetes, showing significant weight loss and improved glucose control. Tirzepatide also reduces insulin dose and increases time-in-range on continuous glucose monitoring.
A researcher is studying patterns of weight gain and BMI increases in children based on behavioral, social, environmental, and biological factors. The study aims to identify monthly patterns in BMI change and associated behaviors.
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Long-term BMI variability was a significant risk marker for adverse cardiovascular events, independent of mean BMI, across major racial and ethnic groups. The study's findings have implications for the phenotype of high BMI variability and potential preventive measures.
A new analysis shows that tirzepatide effectively reduces body weight across different BMI subgroups, achieving significant weight loss of 5% or more in up to 100% of participants. The treatment also demonstrated superior weight reduction compared to placebo in patients with type 2 diabetes.
A collaborative study found that patients with end-stage renal disease who undergo weight loss surgery can experience significant improvements in BMI, hypertension, and diabetes management. This enhancement of overall health and transplant viability offers hope for previously ineligible patients.
New Norwegian research reveals a strong association between parental BMI and offspring's obesity status, even after adulthood. Individuals with both parents living with obesity have six times higher odds of developing obesity in middle age.