Articles tagged with Blood Flow
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Researchers have identified the underlying mechanism behind reduced brain blood flow in Alzheimer's disease, which is caused by pericytes contracting around blood vessels. The study suggests that keeping pericytes relaxed could be a key to treating the disease, with new treatments potentially targeting this area.
Concordia researchers develop a new technique to detect obstructions in bi-leaflet mechanical heart valves, which can help identify potential issues with blood flow. The method uses particle image velocimetry and phase-contrast MRI to simulate blood flow patterns, allowing for non-invasive detection of valve dysfunction.
Researchers found that nilvadipine increased blood flow to the hippocampus, a region affected by Alzheimer's disease, without affecting other parts of the brain. The study suggests that this may slow down the progression of the disease, particularly in its early stages.
Researchers have developed a hybrid device that uses near-infrared light to monitor blood flow, providing a quick and noninvasive diagnosis of cerebral ischemia. The device can record comprehensive profiles of hemodynamics, improving treatment effectiveness within the first few hours of stroke onset.
A new technique using laser angiography illuminated blood flow during laryngectomy surgery, identifying patients at highest risk of wound healing issues. This approach may enable surgeons to adjust during surgery or recovery to improve outcomes, with potential interventions including wider tissue removal and extended hospital stays.
A new method called cardiac functional MRI eliminates the need for injections or physical stress testing, providing a safer and more detailed way to diagnose heart disease. The technique uses oxygenation-sensitive MRI to measure how well the heart's blood vessels are working to deliver oxygen.
A recent study found that people who restricted their blood flow by wearing inflated blood pressure cuffs on an arm and leg showed signs of more controlled blood flow to their brain. The process, called remote ischemic preconditioning, may be beneficial in preventing neurological diseases such as stroke, Parkinson's disease, and epilepsy.
A new nerve stimulation therapy may provide a new treatment option for the most common type of stroke. The study found that this active nerve cell cluster stimulation reduced patients' degree of disability three months after they suffered an acute cortical ischemic stroke.
A team of researchers from Australia, France, New Zealand, and the UK have discovered a group of brain cells that function as a 'master-controller' for the cardiovascular system. These cells, found in the medulla oblongata, coordinate activity across the cardiovascular system, including blood flow to the heart and blood vessels.
Researchers developed a web-based platform to optimize left atrial appendage occluder device therapies for patients with atrial fibrillation and stroke risk. The VIDAA platform combines biophysical models, interactive interfaces, and computational simulations to identify optimal device configurations and positioning strategies.
Researchers develop 3D-printed coronary phantoms to validate CT-FFR diagnostic software, improving non-invasive CAD risk assessment. The phantom models replicate patient vasculature, allowing for physiological testing and efficient validation of CT-FFR estimation methods.
A Rutgers study found that exposure to ultrafine particulates restricts blood flow and nutrients to the uterus, potentially leading to delayed growth and development. Pregnant women are advised to monitor indoor air quality and avoid high-smog days.
Researchers found that people with elevated symptoms of depression were 75% more likely to develop an ischemic stroke than those without depression. This association was seen even after adjusting for other risk factors.
Researchers developed a new approach using ultrasonic registration of blood coagulation in its early stages to prevent thrombosis. The technique involves continuous monitoring of the blood's aggregate state and automatic injection of fibrinolytic drugs, allowing for fast and complete dissolution of formed fibrin clots.
A study from Cornell University has identified the culprit behind decreased blood flow in the brain of people with Alzheimer's: white blood cells stuck to the inside of capillaries. This blockage leads to decreased blood flow in multiple downstream vessels, impacting cognitive function.
A study led by John Wood, MD, PhD, finds that patients with sickle cell disease experience reduced oxygen delivery to the white matter of the brain, despite normal total oxygen delivery. This disparity leads to debilitating silent strokes with significant effects on executive function.
Scientists successfully created functional blood vessels in vitro for rat hearts after a heart attack, resulting in increased blood flow to the engineered tissue. This innovation offers hope for treatments that could help patients regrow heart muscle tissue and achieve more complete recovery.
Researchers compared two groups of patients who underwent clot retrieval with either a balloon-guided catheter or a conventional guide catheter. Patients treated with the balloon-guided catheter showed improved restoration of blood flow scores and clinical outcomes, highlighting its potential to enhance stroke patient care.
Researchers studied blood flow and mechanical networks to understand how biological systems perform tasks. They found that both types of networks can accomplish multiple functions, despite differing physical principles.
Researchers at Northwestern University developed a new tool to image blood flow through tiny capillaries, providing insights into the circulatory system. The 3D-imaging technique can detect subtle changes in capillary organization for early diagnosis of diseases such as cancer and cardiovascular disease.
A study from the University of Virginia Health System found that pre-injury exercise can substantially preserve both muscle and nerve. The research used a 'reporter gene' to measure oxidative stress on muscle and nerves after blood flow restoration, revealing clearer protection through exercise.
Researchers have developed a stent with a sugar-based coating that can facilitate faster and more precise suturing of blood vessels. The stent, designed using 3D printing technology, was tested on pig arteries and showed significant improvements in surgical time and accuracy.
The sensor wraps around the healing vessel and detects changes in electric charge, allowing doctors to monitor blood flow remotely. Researchers are refining their sensitivity and exploring applications for precision health, including telemedicine and early interventions.
A study published in Complementary Therapies in Medicine found that face massage rollers increased facial skin blood flow by up to 25% after just five minutes. Long-term use also improved the vasodilatory response, suggesting a potential mechanism behind its benefits.
Researchers from ITMO University created a non-invasive system to measure blood flow in the upper limbs using video recording of skin surface under green light. The method is comparable in accuracy to traditional methods but is easier to use, cheaper, and suitable for most patients.
Stroke specialists often see conditions known as stroke mimics and 'chameleons' that can mimic ischemic strokes, making accurate diagnosis complicated. Accurate diagnosis requires a detailed history and neurologic examination to avoid administering clot-busting drugs incorrectly.
A large study found that severe cases of prosthesis-patient mismatch after transcatheter aortic valve replacement increase the risk of death and heart failure readmissions by 19% and 12%, respectively. The study identified predictors of PPM, including smaller valve prostheses, larger body surface areas, and female or younger patients.
Scientists detected alterations in capillary blood flow around the face caused by body position change, revealing a response to hydrostatic pressure difference and external stimuli. The non-contact method provides valuable information on peripheral blood flow regulation, potentially leading to new investigations of body responses.
A study found that chronic stress alters blood flow regulation in specific brain regions, including the temporal and prefrontal cortex. The researchers suggest understanding these changes may aid in assessing individuals' risk for stress-related illnesses.
A new non-invasive test called FFRCT accurately reflects invasively measured fractional flow reserve, showing it can safely guide treatment for patients with moderate stenosis. The study found that patients with normal FFRCT results had a similar prognosis to those with mild or no stenosis.
A new study suggests that performing simple leg exercises while lying down can help prevent impairment of blood vessel function caused by a sedentary lifestyle. The research found that even a brief period of inactivity reduced the ability to rapidly increase blood flow to the lower legs.
Neurologist Camilo R. Gomez argues that the effect of time on ischemic stroke outcomes varies greatly among patients, with collateral circulation playing a critical role in determining treatment efficacy. He proposes a new approach to stroke care, taking into account individual patient variability and blood circulation patterns.
Bottlenose dolphin populations vary in diving ability by almost 1000m due to lung architecture and gas management. The research suggests that deep divers use elevated heart rates during surface intervals and directed blood flow through collapsed lung regions to manage nitrogen levels.
Research suggests that oxygen therapy can improve the function of blood vessels in the brains of individuals with chronic obstructive pulmonary disease (COPD), a common cause of dementia. This study found that delivering additional oxygen increased blood flow and oxygen delivery to the brain, matching its demands during activity.
A study published in Radiology found that children with chronic kidney disease exhibit increased cerebral blood flow compared to healthy controls. This may indicate compensatory hyperactivity or disturbances in blood flow regulation, potentially leading to white matter injury and cognitive problems.
Astrocytes and pericytes work together to regenerate cerebral blood vessels in brain regions damaged by stroke. New blood vessels form at the interface between these cells, re-establishing normal blood flow within weeks.
Researchers at UC Davis developed a new technique using conventional digital camera technology to measure brain blood flow. The method, called interferometric diffusing wave spectroscopy, boosts the signal to detect fluctuations in blood motion, providing valuable information about blood flow.
Scientists at Scripps Research Institute have identified a protein called GPR68 that senses blood flow and tells small blood vessels to dilate. This discovery could lead to new treatments for conditions like ischemic stroke and hypertension.
New research confirms blood flow plays a crucial role in cancer metastasis by regulating the position of circulating tumor cells and their exit from the vasculature. The study found that slower blood flow rates are associated with increased metastasis development.
A randomized clinical trial found a smartphone application to have a 94% diagnostic accuracy for assessing blood flow in wrist arteries, surpassing the traditional Allen test. The study highlights the potential of smartphone applications to aid physicians in making decisions at the bedside.
A new study using fMRI scans found that Transcendental Meditation practice leads to a unique state of restful alertness, characterized by increased blood flow to frontal areas of the brain and decreased activity in pons and cerebellum. This finding supports the technique's claim to induce a deeply rested yet alert mental state.
Replacing naturally occurring molecules could reverse symptoms of aging, potentially influencing exercise capacity and physical endurance. The study found that restoring blood flow to tissues and organs with age could be reversed by replicating the benefits of exercise.
A new medicine that slows balding may also improve blood flow to vital organs by increasing arterial diameter and restoring elastin content. This could help reduce the risk of death, stroke, and other cardiovascular-related illnesses.
A team of researchers used a state-of-the-art simulation code to study the behavior of red blood cells flowing through physiologically realistic microvascular networks. They observed that red blood cells frequently jam for brief periods before proceeding downstream, causing temporary increases in vascular resistance. The findings have ...
Patients with critical limb ischemia treated with JVS-100 did not experience faster wound healing compared to those receiving a placebo, despite being in a highly monitored environment. The study's findings highlight the need for additional therapies to aid patients' recovery.
A new study reveals that hemodialysis can decrease cerebral blood flow by 10% in older patients, affecting brain regions including frontal and temporal lobes. This finding may help explain previous studies' links between hemodialysis and worsening cognitive function in elderly patients.
A new study introduces a holistic 3D numerical simulation model of the human heart, taking into account the mutual interaction between blood flow and individual components. The model reveals complex effects of heart strings on the mitral valve, shedding light on potential strategies for preventing cardiac problems.
Researchers have reported significant advancements in measuring blood flow velocity in deep tissues using a handheld ultrasound probe. The new technique, known as photoacoustic flowmetry, has the potential to bring diagnostic capabilities closer to clinical use.
The Society of Nuclear Medicine and Molecular Imaging and the American Society of Nuclear Cardiology have issued joint guidelines for the clinical quantification of myocardial blood flow using Positron Emission Tomography (PET). The guidelines provide a comprehensive framework for the measurement and interpretation of myocardial blood ...
A new mouse study suggests that a high-salt diet can impair blood flow in the brain, leading to cognitive dysfunction. The researchers found that changes in the gut caused by a high-salt diet led to reduced blood flow and dementia-like symptoms in mice.
A high-salt diet reduces resting blood flow to the brain and causes dementia in mice, according to a new study. The study found that mice fed a high-salt diet developed dementia even when blood pressure did not rise, suggesting a direct link between salt intake and cognitive impairment.
A study of nearly 62,000 hospitalizations found that 17.6% of PAD patients were readmitted within 30 days after revascularization procedures, with complications being the primary cause of readmission for 30% of cases. Strategies to prevent readmissions focus on high-risk patients with PAD and improving post-procedure care.
A study found that cerebral blood flow is altered in preterm newborns' brains, with key regions such as the insula and anterior cingulate cortex receiving decreased blood supply. This alteration may serve as an early warning sign of disturbed brain maturation.
A study found that PDA stent placement offered better outcomes than traditional BT shunt operation for infants with ductal-dependent pulmonary blood flow, particularly in experienced centers. Patients who received stents had fewer complications, shorter ICU stays, and larger, more symmetric pulmonary arteries.
Researchers identified a potential drug to protect brain cells after ischemic stroke by mimicking the cellular changes of hibernating ground squirrels. The compound, ebselen, boosts SUMOylation and keeps brain cells alive in the absence of oxygen and glucose.
Scientists discovered a new cell signaling pathway governed by Notch signaling protein that keeps blood vessels intact, which could lead to better drug development and reduce side effects of cancer and cardiovascular treatments. The new pathway operates through a different mechanism than the protein's known transcription-based pathway.
Researchers have developed a method to prolong the survival of stem cells, which could aid in tissue regeneration after blood flow obstruction. By attaching vascular endothelial growth factor to microscopic particles, they increased stem cell lifespan and improved their ability to form new blood vessels.
A study published in Neurology found that older adults with lower cardiac index have reduced blood flow in the temporal lobe regions of the brain, where Alzheimer's pathology begins. This suggests a link between heart health and cognitive impairment, potentially paving the way for new treatments.
A study published in Neurology found that reduced heart blood flow may lead to lower blood flow in the brain's memory centers. The research suggests that mechanisms regulating blood flow become vulnerable with age, potentially leading to cognitive impairment.
A study published in the Journal of Neuroscience suggests that low oxygen levels, not limited blood flow, cause preterm brain cells to fail normal development. This finding opens up opportunities to restore oxygen loss and potentially reduce life-long impacts of preterm brain injury.