Study: Rapamycin prevents age-related brain vascular deterioration
Researchers found rapamycin modifies blood flow and cognitive decline with aging. The study provides evidence that TOR drives loss of synapses and cerebral blood flow during aging.
Blood Flow
Articles tagged with Blood Flow
Pathogenic tau and cognitive impairment are precipitated by a high-salt diet
A high-salt diet can cause cognitive impairment by activating a pathway in the brain that leads to tau protein clumping, according to a new study. The researchers found that this effect is not due to a loss in blood flow to the brain, but rather to the accumulation of tau protein aggregates that interfere with brain cell function.
New study shows huge dinosaurs evolved different cooling systems to combat heat stroke
Researchers from Ohio University used 3D imaging to discover multiple heat exchangers in dinosaur heads and found that giant dinosaurs evolved different cooling systems to combat heat stroke. Different species focused on specific regions, such as the nasal cavity or mouth, to regulate brain temperature.
Stretchable wireless sensor could monitor healing of cerebral aneurysms
A stretchable wireless sensor can monitor the healing of cerebral aneurysms by detecting changes in blood flow. The sensor, fabricated using aerosol jet 3D printing, can be seamlessly integrated onto existing medical stents and measures an incoming blood flow to determine how well the aneurysm is healing.
Prenatal pesticide exposure linked to changes in teen's brain activity
A new study using advanced brain imaging reveals how prenatal exposure to organophosphates affects brain activity in teenagers. Teens with higher levels of exposure showed altered brain activity while performing tasks requiring executive control and linguistic working memory.
SourceUniversity of California - Berkeley·JournalProceedings of the National Academy of Sciences·DateAug 27, 2019
Vaping impairs vascular function
A recent study found that vaping impairs vascular function, reducing blood flow and increasing arterial stiffness in healthy adults. The study used MRI scans to measure the effects of e-cigarette inhalation on the body's vascular system.
Study: Non-invasive electrical stimulation alters blood flow in brain tumors
Researchers at Beth Israel Deaconess Medical Center tested non-invasive electrical stimulation on patients with brain tumors, finding decreased blood flow within tumors while leaving the rest of the brain unchanged. The study suggests that repeated treatments could modify tumor growth and progression.
Evaluating blood flow is key to early diagnosis and treatment for people with critical limb ischemia
The American Heart Association has released new guidelines for diagnosing and treating critical limb ischemia, a condition that affects an estimated 12 million Americans. The guidelines aim to improve the precision and quality of critical limb ischemia management through non-invasive techniques and devices.
Blood pressure monitoring may one day be easy as taking a video selfie
Researchers developed a transdermal optical imaging system that uses facial videos to predict blood pressure with high accuracy. The technology has the potential to become an accessible and convenient method for monitoring blood pressure, particularly for individuals who may not follow traditional cuff-based devices.
Scientists explore blood flow bump that happens when our neurons are significantly activated
Researchers studying functional hyperemia found that blood flow to brain cells increases when neurons are activated, and this response may be beneficial for the health of neurons. The study aims to clarify the link between neural activity and blood flow changes, which could improve our understanding of brain diseases like Alzheimer's.
Blood flow monitor could save lives
A tiny fibre-optic sensor has the potential to save lives in open heart surgery and during surgery on pre-term babies. The continuous cardiac flow monitoring probe is a safe way to give real-time measurement of blood flow.
Changes in blood flow tell heart cells to regenerate
A study in eLife reveals that altered blood flow after heart injury triggers a signalling cascade that promotes cell growth and heart tissue regeneration in zebrafish. The findings provide insights into signalling pathways important for heart regeneration in mammals, including the potential to repair the human heart.
PET/CT detects cardiovascular disease risk factors in obstructive sleep apnea patients
Researchers used PET/CT to evaluate coronary microvascular function in OSA patients and found a link between severe sleep apnea and impaired coronary flow reserve. The study suggests that patients with severe OSA should receive PET myocardial perfusion imaging to exclude coronary microcirculatory dysfunction.
Squeezing of blood vessels may contribute to cognitive decline in Alzheimer's
Researchers have identified the underlying mechanism behind reduced brain blood flow in Alzheimer's disease, which is caused by pericytes contracting around blood vessels. The study suggests that keeping pericytes relaxed could be a key to treating the disease, with new treatments potentially targeting this area.
Concordia researchers develop new method to evaluate artificial heart valves
Concordia researchers develop a new technique to detect obstructions in bi-leaflet mechanical heart valves, which can help identify potential issues with blood flow. The method uses particle image velocimetry and phase-contrast MRI to simulate blood flow patterns, allowing for non-invasive detection of valve dysfunction.
Hypertension drug may hold promise for Alzheimer's disease
Researchers found that nilvadipine increased blood flow to the hippocampus, a region affected by Alzheimer's disease, without affecting other parts of the brain. The study suggests that this may slow down the progression of the disease, particularly in its early stages.
Hybrid device may help doctors treat strokes more quickly
Researchers have developed a hybrid device that uses near-infrared light to monitor blood flow, providing a quick and noninvasive diagnosis of cerebral ischemia. The device can record comprehensive profiles of hemodynamics, improving treatment effectiveness within the first few hours of stroke onset.
A new way to predict complications after larynx cancer surgery
A new technique using laser angiography illuminated blood flow during laryngectomy surgery, identifying patients at highest risk of wound healing issues. This approach may enable surgeons to adjust during surgery or recovery to improve outcomes, with potential interventions including wider tissue removal and extended hospital stays.
SourceMichigan Medicine - University of Michigan·JournalAnnals of Surgical Oncology·DateMay 31, 2019
New imaging tool for diagnosing heart disease
A new method called cardiac functional MRI eliminates the need for injections or physical stress testing, providing a safer and more detailed way to diagnose heart disease. The technique uses oxygenation-sensitive MRI to measure how well the heart's blood vessels are working to deliver oxygen.
Could repeated squeezes to the arms, legs protect the brain?
A recent study found that people who restricted their blood flow by wearing inflated blood pressure cuffs on an arm and leg showed signs of more controlled blood flow to their brain. The process, called remote ischemic preconditioning, may be beneficial in preventing neurological diseases such as stroke, Parkinson's disease, and epilepsy.
Nerve stimulation could provide new treatment option for most common type of stroke
A new nerve stimulation therapy may provide a new treatment option for the most common type of stroke. The study found that this active nerve cell cluster stimulation reduced patients' degree of disability three months after they suffered an acute cortical ischemic stroke.
Optimizing device implantation in patients with atrial fibrillation and risk of stroke
Researchers developed a web-based platform to optimize left atrial appendage occluder device therapies for patients with atrial fibrillation and stroke risk. The VIDAA platform combines biophysical models, interactive interfaces, and computational simulations to identify optimal device configurations and positioning strategies.
Blood flow command center discovered in the brain
A team of researchers from Australia, France, New Zealand, and the UK have discovered a group of brain cells that function as a 'master-controller' for the cardiovascular system. These cells, found in the medulla oblongata, coordinate activity across the cardiovascular system, including blood flow to the heart and blood vessels.
SPIE journal reports advances in use of 3D models in assessing coronary artery disease
Researchers develop 3D-printed coronary phantoms to validate CT-FFR diagnostic software, improving non-invasive CAD risk assessment. The phantom models replicate patient vasculature, allowing for physiological testing and efficient validation of CT-FFR estimation methods.
SourceSPIE--International Society for Optics and Photonics·JournalJournal of Medical Imaging·DateMar 13, 2019
Air pollution may impact fetal cardiovascular system, Rutgers study says
A Rutgers study found that exposure to ultrafine particulates restricts blood flow and nutrients to the uterus, potentially leading to delayed growth and development. Pregnant women are advised to monitor indoor air quality and avoid high-smog days.
Ultrasound for thrombosis prevention
Researchers developed a new approach using ultrasonic registration of blood coagulation in its early stages to prevent thrombosis. The technique involves continuous monitoring of the blood's aggregate state and automatic injection of fibrinolytic drugs, allowing for fast and complete dissolution of formed fibrin clots.
High number of depression symptoms linked to increased risk of stroke
Researchers found that people with elevated symptoms of depression were 75% more likely to develop an ischemic stroke than those without depression. This association was seen even after adjusting for other risk factors.
Researchers closer to new Alzheimer's therapy with brain blood flow discovery
A study from Cornell University has identified the culprit behind decreased blood flow in the brain of people with Alzheimer's: white blood cells stuck to the inside of capillaries. This blockage leads to decreased blood flow in multiple downstream vessels, impacting cognitive function.
The silence of sickle cell disease
A study led by John Wood, MD, PhD, finds that patients with sickle cell disease experience reduced oxygen delivery to the white matter of the brain, despite normal total oxygen delivery. This disparity leads to debilitating silent strokes with significant effects on executive function.
In vitro grafts increase blood flow in infarcted rat hearts
Scientists successfully created functional blood vessels in vitro for rat hearts after a heart attack, resulting in increased blood flow to the engineered tissue. This innovation offers hope for treatments that could help patients regrow heart muscle tissue and achieve more complete recovery.
SourceUniversity of Washington School of Medicine/UW Medicine·JournalNature Communications·DateFeb 5, 2019
Balloon-guided catheters provide better blood flow following stroke interventions
Researchers compared two groups of patients who underwent clot retrieval with either a balloon-guided catheter or a conventional guide catheter. Patients treated with the balloon-guided catheter showed improved restoration of blood flow scores and clinical outcomes, highlighting its potential to enhance stroke patient care.
SourceBoston University School of Medicine·JournalJournal of NeuroInterventional Surgery·DateFeb 4, 2019
Penn physicists find the limits of multitasking in biological networks
Researchers studied blood flow and mechanical networks to understand how biological systems perform tasks. They found that both types of networks can accomplish multiple functions, despite differing physical principles.
SourceUniversity of Pennsylvania·JournalProceedings of the National Academy of Sciences·DateJan 28, 2019
New technology gives unprecedented look inside capillaries
Researchers at Northwestern University developed a new tool to image blood flow through tiny capillaries, providing insights into the circulatory system. The 3D-imaging technique can detect subtle changes in capillary organization for early diagnosis of diseases such as cancer and cardiovascular disease.
Exercise before surgery can protect both muscle and nerves, study suggests
A study from the University of Virginia Health System found that pre-injury exercise can substantially preserve both muscle and nerve. The research used a 'reporter gene' to measure oxidative stress on muscle and nerves after blood flow restoration, revealing clearer protection through exercise.
Sugary stent eases suturing of blood vessels
Researchers have developed a stent with a sugar-based coating that can facilitate faster and more precise suturing of blood vessels. The stent, designed using 3D printing technology, was tested on pig arteries and showed significant improvements in surgical time and accuracy.
Stanford researchers create a wireless, battery-free, biodegradable blood flow sensor
The sensor wraps around the healing vessel and detects changes in electric charge, allowing doctors to monitor blood flow remotely. Researchers are refining their sensitivity and exploring applications for precision health, including telemedicine and early interventions.
Ready for a close-up: The science behind face massage rollers
A study published in Complementary Therapies in Medicine found that face massage rollers increased facial skin blood flow by up to 25% after just five minutes. Long-term use also improved the vasodilatory response, suggesting a potential mechanism behind its benefits.
Scientists developed new contactless method of measuring blood flow in hands
Researchers from ITMO University created a non-invasive system to measure blood flow in the upper limbs using video recording of skin surface under green light. The method is comparable in accuracy to traditional methods but is easier to use, cheaper, and suitable for most patients.
Diagnosing strokes is complicated by 'mimics' and 'chameleons'
Stroke specialists often see conditions known as stroke mimics and 'chameleons' that can mimic ischemic strokes, making accurate diagnosis complicated. Accurate diagnosis requires a detailed history and neurologic examination to avoid administering clot-busting drugs incorrectly.
Prosthetic valve mismatches common in transcatheter valve replacement, ups risk of death
A large study found that severe cases of prosthesis-patient mismatch after transcatheter aortic valve replacement increase the risk of death and heart failure readmissions by 19% and 12%, respectively. The study identified predictors of PPM, including smaller valve prostheses, larger body surface areas, and female or younger patients.
SourceUniversity of Pennsylvania School of Medicine·JournalJournal of the American College of Cardiology·DateSep 23, 2018
Researchers investigate correlation between blood flow and body position
Scientists detected alterations in capillary blood flow around the face caused by body position change, revealing a response to hydrostatic pressure difference and external stimuli. The non-contact method provides valuable information on peripheral blood flow regulation, potentially leading to new investigations of body responses.
Stress and brain blood flow
A study found that chronic stress alters blood flow regulation in specific brain regions, including the temporal and prefrontal cortex. The researchers suggest understanding these changes may aid in assessing individuals' risk for stress-related illnesses.
SourceProceedings of the National Academy of Sciences·JournalProceedings of the National Academy of Sciences·DateSep 10, 2018
Unnecessary heart procedures can be avoided with noninvasive test
A new non-invasive test called FFRCT accurately reflects invasively measured fractional flow reserve, showing it can safely guide treatment for patients with moderate stenosis. The study found that patients with normal FFRCT results had a similar prognosis to those with mild or no stenosis.
Simple leg exercises could reduce impact of sedentary lifestyle on heart and blood vessels
A new study suggests that performing simple leg exercises while lying down can help prevent impairment of blood vessel function caused by a sedentary lifestyle. The research found that even a brief period of inactivity reduced the ability to rapidly increase blood flow to the lower legs.
Rethinking the stroke rule 'time is brain'
Neurologist Camilo R. Gomez argues that the effect of time on ischemic stroke outcomes varies greatly among patients, with collateral circulation playing a critical role in determining treatment efficacy. He proposes a new approach to stroke care, taking into account individual patient variability and blood circulation patterns.
The freediving champions of the dolphin world
Bottlenose dolphin populations vary in diving ability by almost 1000m due to lung architecture and gas management. The research suggests that deep divers use elevated heart rates during surface intervals and directed blood flow through collapsed lung regions to manage nitrogen levels.
Oxygen therapy could help combat dementia in individuals with lung disease
Research suggests that oxygen therapy can improve the function of blood vessels in the brains of individuals with chronic obstructive pulmonary disease (COPD), a common cause of dementia. This study found that delivering additional oxygen increased blood flow and oxygen delivery to the brain, matching its demands during activity.
Children with kidney disease show blood flow changes in brain
A study published in Radiology found that children with chronic kidney disease exhibit increased cerebral blood flow compared to healthy controls. This may indicate compensatory hyperactivity or disturbances in blood flow regulation, potentially leading to white matter injury and cognitive problems.
Stroke: Researchers shed light on the brain recovery process and new treatment strategies
Astrocytes and pericytes work together to regenerate cerebral blood vessels in brain regions damaged by stroke. New blood vessels form at the interface between these cells, re-establishing normal blood flow within weeks.
New technology for measuring brain blood flow with light
Researchers at UC Davis developed a new technique using conventional digital camera technology to measure brain blood flow. The method, called interferometric diffusing wave spectroscopy, boosts the signal to detect fluctuations in blood motion, providing valuable information about blood flow.
Molecule that dilates blood vessels hints at new way to treat heart disease
Scientists at Scripps Research Institute have identified a protein called GPR68 that senses blood flow and tells small blood vessels to dilate. This discovery could lead to new treatments for conditions like ischemic stroke and hypertension.
Blood flow is a major influence on tumor cell metastasis
New research confirms blood flow plays a crucial role in cancer metastasis by regulating the position of circulating tumor cells and their exit from the vasculature. The study found that slower blood flow rates are associated with increased metastasis development.
Smartphone app performs better than traditional exam in cardiac assessment
A randomized clinical trial found a smartphone application to have a 94% diagnostic accuracy for assessing blood flow in wrist arteries, surpassing the traditional Allen test. The study highlights the potential of smartphone applications to aid physicians in making decisions at the bedside.
SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateApr 3, 2018
Discovery offers hope for improving physical performance as we age
Replacing naturally occurring molecules could reverse symptoms of aging, potentially influencing exercise capacity and physical endurance. The study found that restoring blood flow to tissues and organs with age could be reversed by replicating the benefits of exercise.
New study highlights unique state of 'restful alertness' during Transcendental Meditation
A new study using fMRI scans found that Transcendental Meditation practice leads to a unique state of restful alertness, characterized by increased blood flow to frontal areas of the brain and decreased activity in pons and cerebellum. This finding supports the technique's claim to induce a deeply rested yet alert mental state.
Medicine that slows balding may turn stiff vessels supple, helping vital organs
A new medicine that slows balding may also improve blood flow to vital organs by increasing arterial diameter and restoring elastin content. This could help reduce the risk of death, stroke, and other cardiovascular-related illnesses.
The complex journey of red bloods cells through microvascular networks
A team of researchers used a state-of-the-art simulation code to study the behavior of red blood cells flowing through physiologically realistic microvascular networks. They observed that red blood cells frequently jam for brief periods before proceeding downstream, causing temporary increases in vascular resistance. The findings have ...
SourceUniversity of Texas at Austin, Texas Advanced Computing Center·JournalBiophysical Journal·DateMar 15, 2018
Critical limb ischemia treatment shows no improvement at three months
Patients with critical limb ischemia treated with JVS-100 did not experience faster wound healing compared to those receiving a placebo, despite being in a highly monitored environment. The study's findings highlight the need for additional therapies to aid patients' recovery.
New research may explain the link between hemodialysis and brain function decline
A new study reveals that hemodialysis can decrease cerebral blood flow by 10% in older patients, affecting brain regions including frontal and temporal lobes. This finding may help explain previous studies' links between hemodialysis and worsening cognitive function in elderly patients.
SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateMar 1, 2018
3-D simulations reveal synergistic mechanisms of the human heart
A new study introduces a holistic 3D numerical simulation model of the human heart, taking into account the mutual interaction between blood flow and individual components. The model reveals complex effects of heart strings on the mitral valve, shedding light on potential strategies for preventing cardiac problems.