Articles tagged with Dermatology
Urban-living Indigenous children and young people in high-income countries are disproportionately affected by atopic dermatitis and bacterial skin infections, which can lead to serious complications. This systematic review highlights the need for co-designed research with Indigenous communities to address these health inequities.
A team from Massachusetts General Hospital developed an AI-based method to predict which patients with early-stage melanoma are most likely to experience a recurrence. Machine learning algorithms extracted predictive signals from clinicopathologic features, including tumor thickness and rate of cancer cell division.
Researchers highlight climate-sensitive dermatological manifestations initiated or exacerbated by floods, wildfires, and extreme heat events. These events disproportionately affect marginalized populations, exacerbating existing health disparities.
Researchers found a drastic decrease in bacterial abundance on the skin of patients with graft-versus-host disease, while an increased occurrence of staphylococci was observed. This discovery may lead to improved treatment measures for GVHD, which affects approximately 30-70% of stem cell transplant recipients.
A study by MedUni Vienna's Department of Dermatology reveals that tick saliva inhibits the skin's defense function, making it easier for pathogens to multiply. Climate change increases the danger from ticks, which now pose a threat in higher-altitude regions of Austria and well into late autumn.
Researchers explored how differences in skin composition affect susceptibility to diseases like psoriasis and atopic dermatitis. The study found that body site determines skin structure and function, with specific lipids and proteins playing a crucial role in disease diagnosis.
A team of scientists from China published a perspective paper on the use of AI in skin diseases, highlighting its potential to assist clinicians. They propose several recommendations to improve AI-assisted diagnosis systems, including establishing a robust database and adapting algorithms to existing real-world databases.
Lenabasum has been shown to improve skin symptoms in patients with amyopathic dermatomyositis, demonstrating significant reductions in inflammation and disease severity. The study's findings suggest that lenabasum is a well-tolerated treatment option for refractory skin disease.
A new survey of 17,000 Europeans found that 8 in 10 believe tans are attractive and healthy, despite decades of awareness campaigns linking sun exposure to skin cancer and aging. The study also revealed low levels of adherence to sun protection habits, with only 1 in 10 using all forms of protection.
The International Journal of Dermatology calls on dermatologists to take action against climate change by reducing carbon emissions through increased use of telehealth. The authors also emphasize the need for funding prioritization for climate-health research to improve healthcare sustainability and decarbonize the profession.
Researchers identified an immune biomarker in newborns that can predict the onset and severity of pediatric atopic eczema. The Barrier dysfunction in Atopic newBorns (BABY) study found elevated levels of TARC at 2 months to be more than twice as likely to develop eczema by age 2.
A new imaging technique called LC-OCT significantly improved the accuracy of basal cell carcinoma (BCC) diagnosis by 12% compared to clinical and dermoscopic examinations. The technique provided detailed 3D images at a cellular level, enabling more accurate differentiation between BCCs and other skin conditions.
A recent study has found that vitamin D deficiency is associated with lower overall survival rates in melanoma patients. The research, presented at the European Academy of Dermatology and Venereology Congress, suggests that vitamin D levels play a significant role in determining patient outcomes.
A recent study found that private equity firms acquiring physician-owned medical practices increase patient volume and billing for visits, raising concerns about the corporatization of healthcare. The study examined 578 physician practices acquired by private equity firms between 2016 and 2020.
A study by Japanese researchers from Fujita Health University sheds light on the molecular mechanisms of contact dermatitis, revealing that neutrophil extracellular traps play a key role in the condition. The team's findings suggest that inhibiting NET formation could be a new therapeutic strategy for treating contact dermatitis.
A survey study published in JAMA Dermatology found that Asian patients with psoriasis spend significantly less face-to-face time with dermatologists compared to patients of other races and ethnicities. The study highlights the need for improved healthcare access and cultural competence in dermatology care.
Researchers from the University of Gothenburg found that assessing melanoma thickness is challenging for both human dermatologists and machine-learning algorithms. Despite differences in success rates, both groups achieved comparable results when evaluating dermoscopic images, highlighting the need for further study to improve diagnost...
A case series of six patients reported rare skin reaction complications after receiving the Pfizer/BioNTech COVID-19 mRNA vaccine. The study aims to shed light on these unusual side effects.
Researchers found clots in small venous and arterial blood vessels in normal-looking skin from patients with severe COVID-19, distinguishable from other forms of respiratory illness. Antiviral proteins and interferon-induced inflammatory proteins were also detected, associated with disease severity.
This survey study examined associations between demographic and clinical variables and eczema burden in adults. Key findings include identifying factors contributing to eczema severity, which can inform targeted interventions.
A systematic review evaluated patient-reported outcome measures assessing health-related quality of life for adults and adolescents with acne. The review found that these measures can provide valuable insights into the impact of acne on patients' lives, highlighting the need for better standardization and evaluation of these tools.
A randomized, placebo-controlled pilot study found that NB-UVB phototherapy decreased mortality in hospitalized COVID-19 patients with no adverse events reported. The treatment was effective in both vaccinated and unvaccinated patients, with reduced pathologic inflammation and improved intracellular killing of pathogens.
A study has found that there is no single best moisturiser for children with eczema, highlighting the importance of patient education and choice. The trial, funded by the National Institute for Health and Care Research, compared four types of moisturisers and found that reactions were common regardless of type.
A new study found that people over 50 are more likely to use sunscreen if they believe it prevents sunburn, while those who think it takes too much time are less likely. The researchers suggest using reminders from romantic partners or focusing on skin cancer risk as effective messaging strategies.
A new machine-learning tool can speed up the diagnosis of psoriatic arthritis by identifying patients up to 4 years prior to a clinician's diagnosis. The tool, PredictAI, analyzed medical records and accurately identified 32-51% of confirmed PsA patients.
Dermatologists identify a possible link between acne and omega-3 fatty acids, finding that 94% of patients had below-recommended levels in their blood. A healthy diet rich in legumes and avoiding sunflower oil may help manage the condition. The study suggests that omega-3 supplements could be beneficial for treating acne.
Researchers found that normal-appearing lupus skin contains the same inflammatory signals as skin with rashes, suggesting a primed state for inflammation. The study's findings provide new insights into how UV light triggers rashes in lupus patients and highlight the potential for precision medicine in treating the disease.
Recent studies found that pathologists perceive an overdiagnosis of melanoma, with many diagnosing cases as non-invasive melanoma despite variability in diagnoses. A study involving over 100 dermatopathologists showed a majority agree on the issue, but awareness may not be enough to reduce overdiagnosis.
New research found that 62% of tinted sunscreens have only one shade option, with tone compatibility being the most important criterion. The study suggests that the beauty industry and dermatologic field need to improve diversity and offer more options for tinted sunscreen formulations tailored to people with skin of color.
Adults with a history of allergic disorders are at increased risk of developing high blood pressure and coronary heart disease. Asthma is the primary contributor to this risk, particularly among Black male adults.
Patients with serious illnesses seek cosmetic procedures to maintain their physical and mental well-being, as well as to become comfortable in social settings. The study found that these procedures are often chosen for noninvasive treatments and endorsed by doctors, friends, and family.
A new study from the University of Pennsylvania School of Medicine found that patients who underwent facial surgery thought their surgical scars looked worse than surgeons and independent observers did. The researchers suggest that surgeons should counsel patients on what to expect their scars will look like in weeks following surgery.
A systematic review and meta-analysis of seven studies found no significant association between spironolactone use and increased risk of breast, ovarian, kidney, gastric, or esophageal cancers. However, treatment with the drug was associated with a decreased risk of prostate cancer.
Patients with Merkel cell carcinoma face a high risk of recurrence, with 95% of cases occurring within the first three years. The study found that advanced age, male sex, immunosuppression, and known primary lesions are associated with higher recurrence rates, highlighting the need for targeted surveillance efforts.
Researchers at UC San Diego have made a groundbreaking discovery about the role of fibroblasts, or fat cells, in controlling bacteria and developing acne. These findings could lead to more targeted treatment options for acne, which affects up to 50 million Americans each year.
A recent study has identified 29 new genetic variants associated with acne, providing potential new targets for treatment and helping clinicians identify individuals at high risk of severe disease. The research, involving over 20,000 individuals with acne, also found a link between genetic risk and disease severity.
Researchers found sublingual immunotherapy with house dust mite extract to be effective in reducing signs and symptoms of atopic dermatitis. The treatment, administered over 18 months, resulted in significant improvements in pruritus and lesions, with rare side effects.
A UC Davis Health study found that taking bile acids or treatments regulating their production levels can help control psoriasis inflammation. Bile acids inhibited skin inflammation by stopping immune T cells from producing proinflammatory protein IL-17A and blocking immune cell movement to the site.
A review of 392 clinical trials found increased representation of diverse groups in dermatology trials for common skin conditions. The study also highlighted persistent disparities in clinical trial participation among underrepresented populations.
Researchers have developed a cream that prevents frostbite injuries in mice when applied to the skin before severe cold exposure. The cream, called SynAFP, reduces frostbite wound size and speeds healing compared to no treatment. Further studies are needed to determine its effects on humans.
A new algorithm, FusionM4Net, has been developed to classify skin lesions with improved diagnostic accuracy. The algorithm uses a multi-stage data fusion process and outperforms previous state-of-the-art algorithms.
Patients with skin-related side effects from immune checkpoint inhibitors tend to live longer, with a 22-50% decrease in mortality. These findings suggest that skin toxicities can be an indicator of treatment efficacy and may help identify patients who are more likely to benefit from their current immunotherapy regimen.
A new study suggests that sun exposure may reduce the risk of multiple sclerosis in children and young adults by up to 52%. Vitamin D levels are also found to be higher in individuals with increased sun exposure, which may play a role in protecting against autoimmune diseases.
Researchers discovered that wound macrophages undergo different metabolic programs to coordinate tissue repair, including the use of reactive oxygen radicals for blood vessel growth. Macrophages also utilize a different type of mitochondrial exchange for anti-inflammatory and reparative functions in late-stage wound healing.
A Michigan Medicine study combined genetic samples from patients of different ethnic backgrounds, identifying two new psoriasis genetic signals. The inclusion of South Asian subjects allowed researchers to pinpoint several genetic variations within HLA genes that are likely to play a causal role in psoriasis.
A new virtual histology technology may reduce the need for invasive skin biopsies, providing a biopsy-free solution for rapid diagnosis of malignant skin tumors. The technology uses deep-learning frameworks to transform images of intact skin into detailed, virtually stained images.
Researchers have identified specific skin microbiome bacteria and their pathways as contributing to ageing skin. The study, published in PLOS ONE, used a novel approach to chart host-microbe co-metabolism in skin aging.
A survey of 1,300 US dermatologists reveals that 74% identify as LGBT and most disclose their status to patients. The study highlights the importance of creating inclusive workplaces for LGBT healthcare professionals.
Scientists from Japan discover IL-36Ra plays a pivotal role in wound healing, and Cl-amidine normalizes exacerbated I/R injury. The study's findings suggest IL-36Ra as a potential therapeutic target for cutaneous I/R injuries.
A new study reveals that certain strains of Cutibacterium acnes (C. acnes) found on healthy skin can prolong the lifespan of Caenorhabditis elegans and help its innate immune system fight against Staphylococcus aureus. RNA sequencing analysis also shows these beneficial strains activate genes related to innate immunity.
Researchers have discovered a new type of skin cell, TIFFs, that may play a role in inflammatory skin diseases such as scleroderma. These cells were found to interact with immune cells and expand in response to inflammation, leading to an exaggerated response and fibrosis.
Burt's Bees research finds that natural origin ingredients like bakuchiol, aloe, and rice milk improve skin health for all skin types and tones. The studies also show that these ingredients can restore skin barrier function and lead to positive subject-reported improvements.
Researchers identified a bacterium on healthy cats that produces antibiotics against severe skin infections in humans and pets. The discovery may lead to new treatments for MRSP infections in dogs and potentially other inflammatory skin diseases.
Researchers discovered that skin-derived T cells can migrate into the bloodstream and cause inflammation in other organs, such as the intestine. The study provides new approaches to therapy and diagnostic options for stem cell transplantation.
A new study reveals that COVID toes symptoms are caused by an immune response involving high levels of autoantibodies and type I interferon. Endothelial cells also play a crucial role in the development of the condition, according to the research published in the British Journal of Dermatology.
A study published in British Journal of Clinical Pharmacology found a potential link between blood pressure medication use and the development of psoriasis. Data from 13 studies suggests that certain types of antihypertensive medications may increase the risk of skin conditions, warranting close monitoring.
Researchers found glycerin, a natural ingredient in many skin lotions, reduces psoriasis symptoms by calming scaly patches and promoting healthy skin cell maturation. The study's results support anecdotal reports from patients with psoriasis, providing objective evidence of glycerin's effectiveness in combatting the condition.
Researchers found chronic spontaneous urticaria is less severe in children, with lower rates of angioedema and thyroid autoimmunity. Children also respond better to antihistamines compared to adults.
A new EADV survey found that 47.9% of Europeans aged 18+ reported at least one skin condition in the past year, with fungal infections being the most common. The study, involving 44,689 adults from 27 countries, also revealed a lack of homogeneous data on the impact of skin diseases on quality of life.
Researchers discovered a link between genital warts and the human leukocyte antigen system, suggesting genetic variants influence risk. The study found protective gene variations that enhance immune responses against HPV, while risk alleles increase susceptibility to genital warts.