Research on what raises a person's risk of disease and injury. Covers cardiovascular and aneurysm risk, medication in pregnancy, youth behavior, and suicide risk.
Researchers found two new TLR7 gene variants in young, healthy men with severe Covid-19, highlighting the importance of genetic screenings for early intervention. These variants were associated with impaired immune response and increased risk of serious illness, emphasizing the need for preventive vaccination strategies.
Researchers in New Delhi identified a network of 2,512 people who inject drugs, revealing the importance of social interactions and spatial connections on disease transmission. The study found that injecting at popular venues increased HIV and hepatitis C infection risk, and indirect networks also played a significant role.
Researchers determined that a woman's 'vascular age' is a better indicator for cardiovascular disease risk than her chronological age or years since menopause. Hormone therapy brings increased risk of cardiovascular disease, but 'vascular age' provides a clearer answer for physicians making decisions about hormone therapy.
The COVID-19 pandemic has likely led to an increase in falls among older adults due to decreased physical activity, worsened physical conditioning, and heightened fear of falling. This is a pressing concern as falls can result in significant injuries, particularly among this age group.
Researchers at Temple University are conducting a 5-year study to compare two approaches for reducing heart disease risk factors in Black birthing people. The study aims to eliminate disparities in heart disease among Black women and birthing people during and after pregnancy.
The American College of Cardiology has issued clinical guidance on reducing ASCVD risk in patients with persistent hypertriglyceridemia, recommending lifestyle intervention and non-statin therapies. The guidance emphasizes the importance of individualized nutrition guidance for these patients.
Researchers created a new indicator, CPRS, to measure overall cancer risk based on an individual's unique combination of DNA changes. A healthy lifestyle is associated with decreased cancer incidence in people with a high genetic risk.
A study from McGill University and France uses AI to identify factors predicting suicidal behavior in students, finding self-esteem as a major predictor. Approximately 17% of students exhibited suicidal behaviors, highlighting the need for large-scale screening tools.
A new study found that machine learning models incorporating social determinants of health can better capture cardiovascular risk and outcomes for diverse groups. The research emphasizes the need for algorithms to include community-level data and studies that consider more diverse populations.
A study of 19,862 Japanese participants aged 65+ used machine learning to analyze oral and general health. The analysis found robust associations between self-rated oral and general health, with oral health predicting general health more accurately than vice versa.
A large study of over 18 million pregnancies has found a strong relationship between cardiovascular risk factors and poor pregnancy outcomes. Women with multiple pre-pregnancy risk factors, such as obesity and hypertension, were more likely to experience complications like ICU admission, preterm birth, and fetal death.
A new study from Northwestern University found that each additional pre-pregnancy cardiovascular risk factor increases the likelihood of pregnancy complications. Women with multiple risk factors are more likely to experience adverse outcomes such as maternal ICU admission, preterm birth, low birthweight, and fetal death.
A McMaster-led study found that abelacimab prevents blood clots for up to a month after surgery, reducing the risk by about 80% compared to enoxaparin. The treatment also has potential to treat other cardiovascular conditions, such as stroke and deep-vein thrombosis.
The American Academy of Sleep Medicine (AASM) and Sleep Research Society (SRS) have published guiding principles for determining optimal work shift durations. The principles consider factors such as physical and mental fatigue, job requirements, safety risks, lifestyle factors, and health to find a balance between competing goals.
A new study has identified key risk factors for major atrial fibrillation outcomes in patients with hypertrophic cardiomyopathy, including age, obesity, and heart function. The research aims to create a risk-assessment tool to identify high-risk patients and prevent hospitalizations.
A study published in The BMJ found a strong association between ultra-processed food intake and the risk of inflammatory bowel disease (IBD). Consuming five or more servings of ultra-processed food per day was linked to an 82% increased risk of IBD.
Researchers analyzed a large US COVID-19 dataset to assess clinical severity and identify risk factors for severe illness. The study found that machine learning models can accurately predict SARS-CoV-2 infection severity among US adults.
The NIH has expanded its Families SHARE workbook, a tool that helps people use their family history to assess their risk for heart disease, diabetes, breast cancer, and colorectal cancer. The study found that 70% of participants shared the workbook with family members and tried to assess their risk.
A new study found that diagnosis of post-traumatic stress disorder (PTSD) or genetic predisposition to PTSD is associated with increased risk of suicide death among individuals with bipolar disorder. The research suggests that understanding the genetic contribution to PTSD can help identify different strategies for suicide prevention.
A large register-based study found adults with ADHD at higher risk of various physical conditions, particularly nervous system, respiratory, musculoskeletal, and metabolic diseases. The strongest associations were seen for alcohol-related liver disease, sleep disorders, and obesity.
Researchers analyzed data from various sources to identify hospitals that care for disproportionately high numbers of patients with social risk factors. The study found that different risk factor definitions can pinpoint the same hospitals, suggesting a need for targeted interventions to address these disparities.
A new analysis of 58 studies and 44305 patients found that COVID-19 ICU mortality is linked to various risk factors, including smoking, high blood pressure, and respiratory disease. The study also confirms associations between diabetes, cardiovascular, and respiratory comorbidities with mortality in COVID-19 patients.
Researchers in China have created a novel risk score to predict relapse of leukemia, allowing for better medical intervention and stratification of patients with different risks. The study analyzed factors such as engraftment of white blood cells, residual cancer cells, and chronic graft-versus-host disease to determine outcomes like 5...
A new study found that a low Omega-3 Index is associated with increased risk of early death, comparable to the risk of smoking. The research used data from the Framingham Heart Study and suggested that biomarkers integrating lifestyle choices could help identify individuals at risk and inform treatment approaches.
A Finnish-English study published in the Lancet Digital Health found that accelerating risk factor changes can identify high-risk individuals, who may lose 2 to 6 life-years if preventive measures are delayed. An online tool has been developed to study the impact of risk history on estimated cardiovascular disease risk.
A Finnish study published in Acta Diabetologica found that gestational diabetes significantly increases the risk of fetal hypoxia during labor. The risk is nearly seven-fold compared to non-diabetic mothers, and can lead to birth injuries, brain damage, and infant mortality.
A Tel Aviv University study of 10,000 Israeli men found that dissatisfaction with married life significantly predicts death from a cerebrovascular accident and premature death. The study showed that unhappily married men are 69% more likely to die from a stroke than those who rank their marriage satisfaction highly.
A new study identified genetic risk factors for pernicious anemia, a type of anemia caused by vitamin B12 deficiency due to autoimmune reactions. The study analyzed data from over 660,000 individuals and found associations between pernicious anemia and other autoimmune diseases.
Obstructive sleep apnea is common among people with cardiovascular disease, but it's under-recognized and undertreated. Treatment can improve quality of life and reduce risk of cardiovascular events and death.
Research reveals that epigenetic changes contribute to the development of type 1 diabetes, with DNA methylation and histone modifications playing a crucial role. The study suggests that epigenetic markers could be used to monitor disease progression and identify potential therapeutic targets.
The NIH is investing $38 million to develop methods for using polygenic risk scores to predict disease in diverse communities. The new consortium will pool genomic information from existing and new datasets to improve the accuracy of polygenic risk scores across different ancestries.
Researchers found two subgroups of adolescents who self-harm, one with emotional and behavioral difficulties, and a second group without those difficulties but with different risk factors. The study suggests that it may be possible to predict which individuals are most at risk of self-harm up to a decade ahead of time.
A junk food diet may increase the risk of dangerous driving among truck/lorry drivers by boosting fatigue. The study found that vegetable-rich and staple food diets were associated with safe driving behaviours, while animal protein and snack diets were linked to higher rates of errors and unsafe behaviour.
A study of nearly 550 adults with IDD found that age, larger residential settings, Down syndrome, and chronic kidney disease were the most common risk factors for COVID-19 diagnosis. Heart disease was most associated with COVID-19 deaths. The study highlights the need for increased funding for IDD services to ensure better health outco...
Research at the Max Planck Institute found that people over 50 with multiple health risks are more likely to experience depression. However, the severity of depressive moods decreases with age, suggesting a potential psychological component and better coping mechanisms in older adults.
A study published in European Heart Journal found that patients with cardiovascular risk factors are more likely to experience severe outcomes from COVID-19. The research highlights the potential benefits of promoting heart health as a strategy to improve COVID-19 outcomes.
An observational study of over 27,000 US veterans found that risk factors like housing problems and financial hardship were not associated with higher mortality rates among those infected with COVID-19. Instead, the study suggests that other factors such as alcohol use and substance abuse may be more closely linked to increased risk.
A new Northwestern Medicine study found that routine check-ups have several health benefits, including better detection and treatment of chronic illnesses, increased vaccinations and screenings, and improved patient-reported outcomes. These benefits are particularly important for at-risk populations.
A national panel of experts recommends recognizing seven major modifiable risk factors for dementia and taking steps to lower risk through medication, lifestyle changes, and interventions. By controlling vascular risk factors, people can preserve cognitive function and reduce heart attack and stroke risk.
A new study found that consuming mangos can help lower chronic disease risk by improving fasting glucose levels and reducing inflammation. Researchers also discovered that adding herbs and spices to the diet may help lower blood pressure, while ginger, cinnamon, and turmeric supplements were linked with improved cholesterol benefits.
Researchers found a higher De Ritis ratio to be an independent risk factor for cancer progression in high-risk NMIBC patients. Non-BCG treatment was also identified as a risk factor for recurrence.
A new study published by the American Heart Association found that adults with OCD were more than three times as likely to experience an ischemic stroke, with the greatest risk among older adults. Researchers also discovered that medications used to treat OCD did not increase the risk of stroke.
A comprehensive analysis of 437 studies found narcissism is a significant risk factor for aggressive behavior worldwide. Higher levels of narcissism were linked to more aggression, including physical, verbal, and online cyberbullying.
A study analyzing two decades of data reveals parrots are targeted for their attractiveness and ability to be sold on legal markets. The trade has contributed to a severe decline in the global parrot population, with one-third of species threatened by extinction.
Research reveals US cardiovascular disease death rates have decreased nationwide over the past few decades, however disparities between high- and low-mortality counties persist. Counties with higher initial mortality rates remained worse off, while those with lower rates maintained their advantage.
A study published in the Journals of Gerontology: Series A found that a combination of low body mass index and high genetic risk for Alzheimer's disease predicts greater disease progression in men. The research suggests that lower BMI may be a consequence of neurodegeneration, rather than a preventive factor.
Researchers investigated the link between vitamin D levels and SARS-CoV-2 seropositivity in working-age adults, finding no independent association. The study suggests that other risk factors may play a more significant role in determining seropositivity.
Researchers used genetic methods to examine 12 coagulation measures, uncovering four factors associated with migraine susceptibility in individuals with aura. The study suggests a potential causal role of hemostatic factors in migraines with aura.
A study of over half a million people found that certain mid-life cardiovascular risk factors are associated with dementia in both men and women. However, the relationship between blood pressure and dementia risk varies by sex, with higher blood pressure linked to increased risk in women.
A study by Queen Mary University of London compared the safety and effects of heat not burn product IQOS with cigarettes, Juul, and refillable e-cigarettes. IQOS delivered less nicotine, had lower nicotine delivery than Juul, and was less effective in reducing urges to smoke.
Research at ATS 2021 International Conference found a link between severe obstructive sleep apnea (OSA) and increased COVID-19 risk. Patients who adhered to positive airway pressure (PAP) therapy for longer periods had lower infection rates, suggesting PAP has a direct physiological benefit.
A global commission led by Mount Sinai cardiologist Roxana Mehran recommends expanding education and health programs, research on women's heart disease, and prioritizing sex-specific interventions. The report aims to improve women's heart health outcomes worldwide by 2030.
The Lancet Commission report outlines 10 recommendations to improve health outcomes for millions of women worldwide and achieve the global targets set. The report aims to reduce the global burden of cardiovascular conditions in women, including heart disease and stroke, which account for 35% of deaths.
A study published in Human Reproduction found a link between ozone in air pollution and an increased risk of developing fibroids among Black American women. Higher levels of ozone were associated with a 35% increased risk of fibroids, particularly among younger women and those who had been pregnant.
A new study published in the American Heart Association's Circulation Journal found that managing children's weight, blood pressure, and cholesterol may help protect brain function in later life. Researchers analyzed data from the Cardiovascular Risk in Young Finns Study and found a link between early childhood cardiovascular risk fact...
A new study published in Hypertension journal found that hospitalized COVID-19 patients with impaired first-phase ejection fraction are nearly five times more likely to die than those with healthier measures. The research suggests that early detection and prevention of chronic heart damage may be key to improving patient outcomes.
A study of over 5,000 couples found that individuals with a spouse who has heart disease are more than twice as likely to have heart disease themselves. Lifestyle factors such as physical activity, smoking, and alcohol use, as well as caregiver stress, were also identified as contributing to this increased risk.
A study found that Black women as young as their 20s and 30s show high rates of lifestyle-linked risk factors, including obesity and elevated blood pressure. The researchers call for preventive care and lifestyle changes among Black women under age 40 to mitigate the burden of heart disease.
A study published in The BMJ found that ICU admission is associated with a small increased risk of future suicide or self-harm after discharge. Younger patients with pre-existing psychiatric illness and those who received invasive life support were at higher risk, according to the research.
A Swedish-US study found that having a first-degree relative with intestinal polyps increases the risk of developing colorectal cancer. The study, published in the British Medical Journal, included over 68,000 patients with colorectal cancer and 333,753 healthy controls.