Researchers at Brown University have developed a new laboratory test model to investigate fibrosis treatments without the use of animals. The model uses human cells and replicates not only the structure of human tissue but also its mechanics, enabling scientists to study the underlying mechanisms of fibrosis and test potential treatments.
SourceBrown University·JournalAdvanced Science·TypeComputational simulation/modeling·DateFeb 1, 2022
Researchers found that a third of patients with wet age-related macular degeneration can safely stop eye injection therapy without further vision loss. Patients who stopped treatment showed better visual acuity, gain of vision, and less fluid in their retina compared to those requiring continued injections.
SourceJohns Hopkins Medicine·JournalJournal of Clinical Investigation·DateJan 18, 2022
Regrowing healthy cartilage in damaged joints is a promising approach to treating arthritis. UConn bioengineers successfully regrowed cartilage in a rabbit's knee using piezoelectricity, a phenomenon that also exists in the human body.
SourceUniversity of Connecticut·JournalScience Translational Medicine·TypeExperimental study·DateJan 12, 2022
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
The CLASSY gene family controls tissue-specific DNA methylation patterns in Arabidopsis, which has broad implications for agriculture and medicine. The study reveals that CLSY genes modulate DNA methylation patterns in different plant tissues.
SourceSalk Institute·JournalNature Communications·DateJan 11, 2022
The PpeDAM6 gene plays a crucial role in regulating plant bud dormancy, responding to environmental conditions and hormonal signals. The study reveals the interaction between PpeBPCs and PpeDAM6, highlighting the importance of epigenetic regulation in modulating cell growth and tolerance to abiotic stresses.
SourceNanjing Agricultural University The Academy of Science·JournalHorticulture Research·DateDec 21, 2021
Dysfunction in mitochondrial respiration leads to imbalanced extracellular matrix (ECM) and tissue organization in cartilage. Research discovered the respiratory chain plays a key role in maintaining ECM balance.
SourceUniversity of Cologne·JournalJournal of Biological Chemistry·TypeExperimental study·DateOct 7, 2021
Scientists create a cell culture system where blood vessels can grow within a framework made of synthetic materials. The team investigates material properties that promote blood vessel formation and refines the model to improve its performance, paving the way for growing implantable tissues.
SourceMax-Planck-Gesellschaft·JournalNature Communications·TypeExperimental study·DateAug 22, 2021
A preclinical study found that high-fructose diets alter villi in the small intestine, leading to increased nutrient absorption and weight gain. Fructose's primary metabolite promotes elongation of villi and supports intestinal tumor growth.
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A new ultrasonic method improves fetal weight prediction accuracy by analyzing three-dimensional limb volumes and abdominal circumferences. The algorithm outperforms traditional formulas in predicting macrosomia and birth weights.
SourceCactus Communications·JournalChinese Medical Journal·TypeData/statistical analysis·DateAug 3, 2021
Chromosomal instability linked to cellular senescence in Drosophila study reveals mechanisms that could lead to reduced tumour growth and malignancy. Senescent cells cause inflammation and promote abnormal tissue growth.
SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalDevelopmental Cell·DateJul 6, 2021
Scientists at the University of Helsinki discovered that ECM protein Lama5 guides the growth and differentiation of epithelial cells in breast tissue, especially during pregnancy. The production of Lama5 strengthens the functionality of hormone-sensitive cells, allowing them to relay signals and support tissue growth.
SourceUniversity of Helsinki·JournalDevelopment·DateJul 1, 2021
Scientists at the University of Tennessee Institute of Agriculture are working on developing biobased peptides to restrict ice crystal growth in freezing temperatures. Successful methods could improve frozen food quality, increase crop resistance to freezing temperatures, and enhance biomedical research.
SourceUniversity of Tennessee Institute of Agriculture·DateJun 29, 2021
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
New research reveals coral can fight back against juvenile crown of thorns starfish with stinging cells, damaging their arms and delaying growth. The study shows coral's defensive mechanism may not be enough to protect it from other threats like climate change.
SourceUniversity of Sydney·JournalMarine Ecology Progress Series·DateMay 4, 2021
Researchers from MIPT and ITMO University have created a system for controlled formation of melamine cyanurate crystals, which can be used to deliver drugs directly to specific tissues in the human body. The discovery opens up new possibilities for targeted drug delivery technology.
SourceMoscow Institute of Physics and Technology·JournalCrystal Growth & Design·DateMar 22, 2021
A team of researchers from the University of Warwick has discovered that even short chains of poly(vinyl alcohol) bind to ice and inhibit recrystallization. This finding sheds new light on the fundamental principles of ice recrystallization, enabling the design of more effective cryoprotectants.
SourceUniversity of Warwick·JournalNature Communications·DateMar 15, 2021
A study found that early exposure to heat and low oxygen can leave lasting scars on oysters' ability to grow tissue. Oysters invested more in growing their shells than tissue when exposed to the double punch of low oxygen and warmer waters. This could pose a problem for anyone involved in the seafood industry.
SourceSmithsonian·JournalEcological Applications·DateMar 1, 2021
Researchers from Osaka University and colleagues found that plant root tips converge to a dome shape, similar to arch bridges, due to localized tissue growth. This shape helps evenly distribute mechanical force, enabling roots to efficiently push through soil.
SourceOsaka University·JournalDevelopment·DateMar 1, 2021
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
A new technique developed by Brown University researchers reveals the forces involved at the cellular level during biological tissue formation and growth processes. The technique makes use of cell-sized spheres made from a highly compliant polymer material, which can be placed in laboratory cultures of tissue-forming cells.
SourceBrown University·JournalBiomaterials·DateFeb 5, 2021
Researchers from Osaka University successfully generated functional conjunctival tissue in a dish, enabling the study of conjunctivae and the development of novel drugs for dry eye disease. The newly formed tissue contained goblet cells that produce mucins, mimicking human conjunctival biology.
SourceOsaka University·JournalCell Reports·DateFeb 2, 2021
Researchers developed ice recrystallization inhibitors to halt ice growth in frozen samples, improving cell recovery and function. The technology prevents cellular damage caused by ice crystals, allowing for more efficient storage and transport of biological materials.
Plant roots can sense compacted soils through ethylene hormone signals, hindering growth. Mutant roots insensitive to ethylene penetrate compacted soils more effectively.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience·DateJan 14, 2021
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
The SCOUT pipeline enables quantitative comparisons among unique organoids by extracting comparable features. Researchers use it to identify patterns in cell configurations, highlighting similarities and differences across organs
SourcePicower Institute at MIT·JournalScientific Reports·DateDec 8, 2020
A UMass Medical School study finds that low levels of PAPPA, commonly screened for chromosomal disorders, are associated with adipose tissue remodeling and gestational diabetes. The protein is linked to insulin-like growth factor-1 (IGF-1), which promotes healthy adipose tissue development during pregnancy.
SourceUMass Chan Medical School·JournalScience Translational Medicine·DateNov 30, 2020
A novel bypass route for coronary vessels in the heart has been discovered using the VEGF-B growth factor, which can stimulate new blood vessel growth in damaged areas. This finding opens up possibilities for treating myocardial infarction by re-activating embryonic vessel growth programs.
SourceUniversity of Helsinki·JournalCirculation Journal·DateNov 19, 2020
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Researchers developed an algae-based 3D bioprinting method to incorporate vascular patterns within engineered tissues and provide a sustainable source of oxygen for human cells. The approach showed promise for applications in disease modeling, drug development, regenerative and personalized medicine.
Research using functional MRI found that brain networks involved in movement planning and execution are activated differently based on the type of movement performed, even when using different body parts. The study suggests that these brain functions emerge from innate constraints in early development.
SourceProceedings of the National Academy of Sciences·JournalProceedings of the National Academy of Sciences·DateOct 26, 2020
Researchers found that a protein called Rictor plays a key role in regulating stem cell metabolism, which can help prevent hair loss. The study used a genetic mouse model to demonstrate that the absence of Rictor protein impaired stem cell function and led to hair loss.
SourceUniversity of Helsinki·JournalCell Metabolism·DateOct 13, 2020
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers have identified NRXN1, a cell adhesion molecule, as a potential target for antibody-drug conjugate (ADC) therapy in small cell lung cancer. The study found that targeting NRXN1 with ADCs exhibited anti-tumor activity in SCLC cells.
SourceImpact Journals LLC·JournalOncotarget·DateSep 30, 2020
Researchers at EPFL create miniature intestines using stem cells and hydrogel scaffolds, achieving high physiological relevance. The new organoids can regenerate, model inflammatory processes, and host-microbe interactions, opening up exciting perspectives for disease modeling, drug discovery, diagnostics, and regenerative medicine.
SourceEcole Polytechnique Fédérale de Lausanne·JournalNature·DateSep 16, 2020
Researchers document rapid acceleration and thinning of Pine Island and Thwaites Glaciers in Antarctica. The growth of damage areas on the ice shelves compromises integrity and drives further disintegration, highlighting the importance of incorporating damage processes into ice sheet models.
SourceProceedings of the National Academy of Sciences·JournalProceedings of the National Academy of Sciences·DateSep 14, 2020
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
Researchers identified key drivers of secondary growth resumption in Northern Hemisphere conifers, including photoperiod and mean annual temperature. These factors interact with spring forcing and moisture availability to regulate wood formation.
SourceChinese Academy of Sciences Headquarters·JournalProceedings of the National Academy of Sciences·DateAug 4, 2020
Scientists have discovered a compound in the American beautyberry leaves that works in combination with oxacillin to knock down resistance to the drug methicillin-resistant Staphylococcus aureus, or MRSA. The study suggests a new potential therapy for treating antibiotic-resistant infections.
SourceEmory Health Sciences·JournalACS Infectious Diseases·DateJul 16, 2020
Researchers at CU Boulder have discovered a synthetic molecule that mimics natural antifreeze proteins, minimizing freeze-thaw damage and increasing the strength of concrete. This new method challenges conventional approaches and has the potential to reduce costs and decrease carbon emissions.
SourceUniversity of Colorado at Boulder·JournalCell Reports Physical Science·DateMay 27, 2020
A preclinical study led by Children's Hospital Los Angeles surgeon Tracy Grikscheit successfully grew a fully functional gut nervous system in a pre-clinical model, offering hope for babies with Hirschsprung's disease. The study uses tissue engineering to grow the complete nervous system from scratch.
SourceChildren's Hospital Los Angeles·JournalJournal of Tissue Engineering·DateMay 22, 2020
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Scientists studied mouse tail skin expansion from birth to adulthood, finding that it grows by a factor of 15 through self-duplication of developmental progenitors. Cell proliferation rates decreased over time, while single-cell RNA sequencing revealed molecular features of developmental progenitors.
SourceUniversité libre de Bruxelles·JournalCell·DateApr 29, 2020
A new combination of 3D printing and acoustic droplet ejection technology enables precise control over growth factor presentation, promoting osteogenic differentiation in C2C12 mouse myoblast cells. This technique has vast potential for various tissue types beyond bone engineering.
SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalTissue Engineering·DateApr 15, 2020
Pulsed electromagnetic field therapy significantly decreases prostate volume and improves lower urinary tract symptoms in men with benign prostatic hyperplasia. Men without metabolic syndrome benefit most from the treatment.
SourceParsemus Foundation·JournalAndrology·DateApr 9, 2020
Researchers have identified a gene linked to brain cancer in children that can aid in diagnosis and treatment. Elevated levels of the TPR gene were found in 38% of ependymoma cases, and its deletion led to reduced cancer growth and tumor shrinkage when treated with rapamycin.
Researchers at Stanford University have discovered the invisible pattern that growing neurons follow to form a brain using microscopy and mathematics. The technique could be used to coax stem cells to grow into replacement body parts, such as artificial organs.
SourceStanford University School of Engineering·JournalNature Physics·DateMar 11, 2020
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
Researchers at IRB Barcelona discovered that Dpp and Wg morphogens stimulate growth through independent pathways, regulating organ proportions. The findings have significant implications for understanding malformations and congenital diseases in humans.
SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalDevelopmental Cell·DateFeb 21, 2020
Researchers have identified three proinflammatory mediators driving capillary regression, a common feature of many diseases. The study found that combining drugs to block these mediators can prevent capillary loss and improve outcomes.
SourceUniversity of South Florida (USF Health)·DateJan 29, 2020
Researchers have identified a genetic signaling pathway that limits tissue growth in planarian flatworms, allowing for precise regeneration and repair. The mob4 gene suppresses tissue growth by preventing the production of Wnt, a protein involved in cancer cell regeneration.
SourceNorthwestern University·JournalCurrent Biology·DateJan 22, 2020
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Old Ginkgo biloba trees display similar gene expression for flavonoids and other resistance genes in young and old trees. Increasing age is not accompanied by a significant decrease in leaf area or growth rate, suggesting that these trees may stay healthy due to robust stress defenses.
SourceProceedings of the National Academy of Sciences·JournalProceedings of the National Academy of Sciences·DateJan 13, 2020
Researchers at the University of Birmingham propose a groundbreaking design approach for additive manufacturing inspired by human growth and development. By leveraging insights into developmental biology, they unlock new potential for the creation of innovative materials and products.
SourceUniversity of Birmingham·JournalThe International Journal of Advanced Manufacturing Technology·DateJan 10, 2020
Researchers have identified a genetic program controlling the development of beige fat cells, which can convert energy into heat. The study's findings suggest that people with more thermogenic fat cells may be less likely to develop obesity and related metabolic disorders.
SourceTechnical University of Munich (TUM)·JournalCell Reports·DateJan 9, 2020
Researchers studied the cup-shaped traps of Utricularia gibba and found that differential rates and orientations of growth are involved in shaping. A polarity field comparable to that proposed for flat leaves was also detected, providing a unified explanation behind diverse leaf forms.
SourceJohn Innes Centre·JournalPLOS Biology·DateOct 10, 2019
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Researchers developed a framework to describe the process of ultrastructural morphogenesis of molluscan shells. They demonstrated that mineral phase growth is guided by regulating chemical and physical boundary conditions, influencing shell architecture and evolution.
SourceTechnische Universität Dresden·JournalProceedings of the National Academy of Sciences·DateSep 24, 2019
Researchers analyzed 33 studies on laser-induced forward transfer (LIFT) bioprinting to optimize techniques and materials. They found that LIFT technology provides precise cell transfer and precise 3D printing capabilities, with potential applications in tissue transplantation.
SourceSechenov University·JournalBioprinting·DateAug 20, 2019
New research suggests that understanding plant biological clocks can refine the use of chemicals like glyphosate, allowing for more efficient and sustainable agriculture practices. By applying treatments at optimal times, farmers can reduce herbicide usage, saving time and money while minimizing environmental harm.
SourceUniversity of Bristol·JournalNature Communications·DateAug 16, 2019
Research reveals lavender oil exposure contributes to premature breast development in young girls and boys. Discontinuing use of lavender-containing products resolves the issue, suggesting essential oils mimic estrogen and block testosterone.
SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateAug 14, 2019
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
A new approach from Harvard researchers uses a biomaterial scaffold and childhood vaccines to attract and activate T cells that promote revascularization of ischemic tissues. The technique increases the concentration of T cells at the ischemic site and stimulates angiogenesis, blood flow, and muscle fiber regeneration.
SourceWyss Institute for Biologically Inspired Engineering at Harvard·JournalScience Advances·DateJul 31, 2019
Researchers identified a crucial protein, Tox, that triggers dysfunctional immune responses in the body. This 'exhaustion mode' can be beneficial as it prevents excessive damage to cells and tissue but also allows tumor growth.
SourceTechnical University of Munich (TUM)·JournalNature·DateJun 18, 2019
Scientists at Stanford University School of Medicine have discovered a molecular pattern that flags prostate enlargement and identified two genes likely playing a role in its development. The researchers found that only certain cell types multiply, leading to a fundamental shift in the type of cells making up the prostate.
Researchers have created a new type of hydrogel that can grow new tissue to heal wounds, eliminating the need for external growth factors. The hydrogels are made with biomolecules anchored in crosslinkers and can be mixed at room temperature.
SourceRice University·JournalScience Advances·DateJun 5, 2019
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Researchers at Universite Paris-sud studied how collagen fibrils form complex tissues. They found that the fibers grow in a unique, parabolic profile, with a constant diameter throughout growth, similar to a sunflower's florets.
SourceSpringer·JournalThe European Physical Journal E·DateMay 13, 2019
Researchers at CNIC have identified a cellular and molecular mechanism that can induce productive angiogenesis in ischemic tissues. The newly discovered mechanism suggests that manipulating it could lead to optimal therapeutic angiogenesis, which may help treat cardiovascular disease.
SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalNature Communications·DateMay 1, 2019
Researchers discovered that stem cells in the neural retina act as 'bosses' during growth, telling cells in the retinal pigment epithelium when to create more cells. The study reveals an unappreciated mechanism for growth coordination, where one tissue gives cues to synchronise the growth of nearby tissues.
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Researchers at Kazan Federal University have developed a two-gene medication that recovers motor functions in rats after spinal cord injuries. The medication, which targets VEGF and FGF2 genes, stimulates axon growth and regeneration by increasing blood flow and neuron survivability.
SourceKazan Federal University·JournalNeural Regeneration Research·DateMar 18, 2019
New research suggests that moderate water intake can reduce kidney cyst growth and fibrosis in people with polycystic kidney disease (PKD). Increased water consumption was also found to have secondary benefits, including reducing high blood pressure and cardiovascular risks associated with PKD.
SourceWestmead Institute for Medical Research·JournalPLOS ONE·DateMar 6, 2019
Research by De Rybel (VIB-UGent) and Helariutta (SLCU) reveals that DOF-type transcription factors control plant radial growth, enabling targeted breeding for higher biomass production. This understanding can improve atmospheric carbon sequestration and increase crop yields.
SourceVIB (the Flanders Institute for Biotechnology)·JournalCurrent Biology·DateFeb 8, 2019