Articles tagged with Parasitic Diseases
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A new species of mosquito, Culex modestus, has been discovered in Finland, adding to the country's mosquito species count. The discovery is an important addition to the understanding of mosquitoes and their potential pathogens, with no reported cases of West Nile virus transmission in humans or horses.
Researchers at the University of São Paulo identified a protein in Amblyomma ticks essential to their survival while feeding, making it a promising target for developing a vaccine. The study found that silencing gene expression of an inhibitor of apoptosis protein reduced bacterial proliferation and made ticks more resistant to infection.
Researchers at Osaka University developed a highly reproducible genetic screen to investigate Toxoplasma's survival within hosts. The study identified IFN-γ-dependent and -independent virulence factors that promote parasite fitness, providing potential targets for treatment and prevention of toxoplasmosis.
Scientists studying Leishmania parasites found that they can adapt quickly to drug resistance by altering gene expression and protein synthesis. This understanding could lead to more effective targeted treatments by removing specific genes or interrupting information flow.
Researchers uncovered traces of Giardia duodenalis, a common cause of debilitating diarrhoea, in two Jerusalem latrines dating back to the biblical Kingdom of Judah. The study suggests dysentery was endemic in the Kingdom of Judah.
Researchers at York University found more pathogens and parasites in urban bee populations, leading to inbreeding and reduced genetic diversity. Conservation efforts focused on green spaces and habitat connectors can help mitigate these effects.
Researchers at IOCB Prague have determined the first cryo-EM structures of a surface receptor of Trypanosoma brucei gambiense in complex with human complement factor C3. This discovery sheds light on how the parasite avoids clearance from the human bloodstream and survives within the immune system.
Researchers identified a protozoan parasite as the cause of mass sea urchin die-offs in the Caribbean, which has devastating effects on coral reefs and fish populations. Healthy coral means healthy fish, and their positive impacts continue up the food chain.
A parasite identified as Philaster apodigitiformis has been found responsible for the massive die-off of long-spined sea urchins in the Caribbean Sea. The loss of these vital herbivores threatens coral reef health and balance, with devastating consequences for marine ecosystems.
A new study found that sunflower pollen's spiny structure reduces infection of a common bee parasite by 81-94% and increases the production of queen bumblebees. The research also suggests that other flowers in the sunflower family may have similar disease-fighting powers.
A new finger-prick test for Trichomonas vaginalis has been developed by Washington State University researcher John Alderete. The test detects an antibody specific to the organism and provides rapid, affordable results, making it a potential game-changer in the fight against this prevalent but neglected STI.
Researchers used cryo-electron microscopy to visualize the protein synthesis mechanism in Giardia intestinalis, resolving high-resolution structures of six different states of elongation. These findings provide valuable information for screening specific drugs against Giardia and other protozoan parasites.
A recent study found that the highly contagious chytridiomycosis fungus has become more prevalent and widespread in Africa since 2000, posing a new threat to amphibian populations. The disease, which can cause skin sloughing, lethargy, weight loss, and cardiac arrest, may be linked to climate change-induced stress.
A study found that high winds increased Campylobacter prevalence in outdoor chicken farms, with 26% of individual chickens infected. Farmers are advised to consider windbreaks and monitor weather patterns to reduce exposure.
A study found 38% of children in a rural Mississippi Delta community had parasitic worms or protist infections. This is a neglected health issue in low-resource areas, linked to poor sanitation and climate change. The researcher emphasizes the need for direct community engagement and investment in infrastructure to address these issues.
In a study published in the Proceedings of the Royal Society of London B, researchers found that mandrill females pass on hygienic practices to their daughters, reducing parasite infection. This social transmission of hygiene has potential consequences for infectious disease dynamics in primate groups.
A high-fat diet allows the immune system to eliminate a parasitic worm that causes long-lasting infections in the large intestine. This discovery may lead to new treatments for millions suffering from intestinal parasitic infections worldwide.
A new microbiome therapeutic, SER-109, has been shown to improve the quality of life of patients with Clostridium difficile (C. diff) infections by reducing symptoms and restoring colonization resistance. The treatment was found to be associated with significant improvements in health-related quality of life scores as early as Week 1.
Researchers have identified a new class of potent antimalarial compounds that target the parasite's sexual phase, preventing it from infecting mosquitoes and subsequently humans. The compounds inhibit the parasitic protein Pfs16, forming the strongest bond with the drug.
A study found that a small number of Varroa mites can infect many adult honey bees, with high-risk mites spreading pathogens through frequent host switching. This mechanism amplifies the vectorial capacity of Varroa destructor.
A recent study found that medical professionals in Illinois were relatively knowledgeable about diagnosis and treatment of Lyme disease, but lacked information on other tick-borne diseases. The researchers are now designing a continuing education course to educate practitioners on current ranges of ticks and risk of disease.
A study from the University of California, Davis' One Health Institute found that canine echinococcosis increased to 6.9% in Tierra del Fuego's sheep farms after the government cancelled a deworming program in 2004. Reestablishing the program could help protect people and animals from hydatid disease.
A study published in PLoS Genetics reveals the mechanism by which a selfish gene in yeast, wtf4, enables its function using a poison-antidote strategy. This strategy involves the production of poison protein that can kill spores, but is countered by an antidote protein produced only by those spores that inherit the drive allele.
A new review paper aims to educate medical professionals on diagnosing and treating rat lungworm disease, which is expected to spread globally due to climate change. Early diagnosis and treatment are critical in reducing the risk of complications such as long-term disability.
Research highlights the need for high-quality studies on tropical cyclones in low- and middle-income countries to understand long-term consequences. The public health impact extends beyond injuries and cardiovascular diseases, affecting neuropsychiatric conditions and infectious diseases.
Researchers have detected five emerging tick-borne pathogens in Central Canada, including those causing Lyme disease and babesiosis. Climate change and habitat fragmentation contribute to the spread of these pathogens, highlighting the need for increased awareness and protection measures.
Researchers have discovered that leprosy parasites can reprogram liver cells to increase organ size without scarring or tumors. This natural process may be adapted to renew ageing livers and improve healthspan in humans.
Co-infection with gut parasites increases shedding of respiratory bugs like Bordetella bacterium, leading to higher probability of onward transmission. This study in rabbits has broad implications for human populations and suggests targeting treatment of helminths could be an effective way to reduce disease outbreaks.
A type of dietary fiber called inulin alters gut bacteria metabolism, triggering type 2 inflammation in the gut and lungs. Inulin boosts Treg cells but also induces higher levels of eosinophils, a classic sign of type 2 inflammation.
A new study led by Weill Cornell Medicine researchers offers insight into the immune mechanisms of inflammatory disease. Group 2 innate lymphoid cells (ILC2s) have an essential role in protecting tissues from parasitic infections and allergic inflammation.
Researchers found that sapanisertib can kill the malaria parasite at several stages during its life cycle, including in the liver and red blood cells. The study's findings offer new hope against a disease that kills over half a million people annually.
Researchers discovered that plants can regulate their microbiome through the secretion of flavonoids, which affect beneficial and harmful microorganisms around plant roots. This delicate balance helps protect plants from parasitic nematodes, reducing susceptibility to infection.
A VUB study has mapped the immune system's response to brain infections, revealing that resident macrophages play a key role in defending against pathogens. The researchers found that blood-derived immune cells can eliminate parasites, but may retain 'memory' of past infections, altering their ability to respond to future insults.
A WVU biomedical engineer is working on a rapid diagnostic tool that can detect tick-borne infections such as Lyme disease via a blood sample on a single chip. The tool uses dielectrophoresis and machine-learning to detect diseases within one to two weeks after onset, reducing the risk of hospitalization and chronic conditions.
A new, shorter combination treatment has been shown to be effective in treating visceral leishmaniasis in Eastern Africa. The treatment, which combines miltefosine and paromomycin, is safer and reduces hospitalization time by 18%, eliminating the need for painful daily injections.
Researchers from Ludwig-Maximilians-Universität München have deciphered a crucial signaling mechanism that enables trypanosomes to reach the salivary glands of tsetse flies. By understanding this process, scientists can develop new methods to prevent transmission of African sleeping sickness.
Research reveals that 32 species of animals, including prawns, crabs, and lizards, can act as carriers of the rat lungworm parasite, which can cause serious illness and death. The study aims to raise awareness about paratenic hosts and prevent infection by avoiding eating raw or infected animals.
A study of medieval Cambridge's Augustinian friary and local cemetery found that friars were almost twice as likely to be infected by intestinal parasites. The researchers suggest that the high infection rates among friars may have been due to their practice of manuring vegetable gardens with human faeces.
Cognitive impairment can lead to population declines, particularly for species relying on learning and memory. Infections can impact cognitive abilities differently across animals, depending on their survival strategy and pathogen manifestation.
Researchers found that different lineages of Cryptosporidium parvum are increasingly exchanging their DNA, which helps the parasite evolve faster and potentially result in more virulent strains. The study suggests that globalization and close contact with animals increase the rate of genetic exchange.
Researchers found no association between social behavior and parasite infection in Asian elephants, despite studying three key aspects of their social life. The study suggests that social benefits may outweigh the costs of sociality for these animals.
A new digital PCR technique helps identify mutations in malaria parasites that evade detection by rapid tests, reducing false negatives. This allows for more accurate selection of diagnostic tests tailored to specific regions.
Researchers found that flower shape is a key predictor of parasite transmission to bees, with wider, shorter flowers increasing the risk. The study suggests that identifying floral traits and species associated with lower parasite transmission rates could help create pollinator habitats with reduced disease risk.
A UVA researcher is using a harmless amoeba to develop an innovative treatment for deadly C. difficile infections in young children. The approach has the potential to deliver specific antibodies directly to the gut, reducing the need for antibiotics and addressing a growing public health threat.
A WHO-supported series has collected 13,700 new database records on mosquito-borne diseases, providing valuable resource for studying and containing infectious diseases. The data can be used to train machine-learning models for vector detection and classification, improving global human health.
A new analysis of ancient faeces found at Durrington Walls has uncovered evidence of parasitic worms, suggesting the inhabitants feasted on cattle and fed leftovers to their dogs. The findings indicate that people ate raw or undercooked internal organs from infected animals, resulting in parasite eggs passing through the body.
A study led by Washington University in St. Louis found that nonlethal parasitic infections reduce herbivory rates and trigger trophic cascades impacting plant communities. The research used a mathematical model and global meta-analysis to highlight the ecological consequences of common parasitic infections in wild animals.
Two fatal cases of airport malaria were reported in Belgium, highlighting the need for healthcare awareness near airports. The most likely route of transmission was through an imported infectious exotic Anopheles mosquito that was possibly brought via the international airport or military airport.
Research reveals high rates of parasitic worm infections in ancient British populations, particularly during the Roman and Medieval periods. The study sheds light on the lives and habits of past populations, providing insights into public health measures.
A new study by University of Waterloo researchers highlights the need for a multi-faceted approach to prevent infections from becoming harder to treat due to antimicrobial resistance.
Key signalling pathways blocking by existing drug candidates limit CCHF virus reproduction. The findings offer hope for patients affected by this deadly disease, which has a high mortality rate in humans.
A study led by the University of Minnesota Medical School found that exposure to helminths can stimulate the immune system and reduce predisposition for inflammatory bowel disease. The research revealed a unique glycosylation mechanism, O-GlcNAcylation, which activates epithelial cells to orchestrate an anti-helminth response.
Researchers have discovered that P. malariae, a malaria parasite infecting humans, originated in African apes before evolving to infect people. This breakthrough reveals the evolutionary links between the two species and sheds light on how the parasite adapted to infect humans.
Researchers discover that common herbicides can kill the Toxoplasma gondii parasite without harming human cells. The compounds work by inhibiting heme biosynthesis, a promising approach for treating toxoplasmosis.
A new mechanism has been discovered that decorates the end tails of RNA molecules in a parasite causing sleeping sickness, preventing their degradation and potentially increasing virulence. This fundamental discovery opens new avenues for treatment strategies for this disease, as well as other RNA-based infections/diseases.
A novel class of bed net that kills mosquitoes resistant to traditional insecticides by making them unable to move or fly significantly reduces malaria infection in children. The study found a 43% reduction in malaria prevalence and 44% reduction in clinical episodes over two years.
Researchers found that Chagas trypanosomes change the bacterial community in predatory bugs' intestines, leading to a decrease in diversity and an increase in certain pathogenic bacteria. The study also identified four bacteria species crucial for bug survival, which could be used to develop defensive substances against the parasite.
A new analysis from Emory University reveals a significant increase in the parasitism rate of monarch butterflies over 50 years, with the O.E. parasite infecting up to 10% of eastern monarch populations. The rise in infection rates may endanger the mass migration of monarchs, threatening their survival.
A new study by Emory University finds that schistosome transmission can be highest when freshwater snail populations are low. Snails competing for resources may lead to lower infectivity rates, contrary to typical pesticide-based control methods.
Scientists at UCR have discovered a new species of nematode parasite that infects and kills tarantulas, exhibiting strange behaviors like walking on tiptoe and loss of fang control. The parasite, Tarantobelus jeffdanielsi, is named after actor Jeff Daniels, who saved fictional spiders in the 1990 film Arachnophobia.