A new study reveals that stevioside can effectively promote hair follicles to enter the growth phase when combined with minoxidil. The natural sweetener enhances skin absorption of the drug, leading to new hair development in a mouse model of alopecia.
Researchers at Nagoya University found that luteolin, an antioxidant in vegetables, can suppress hair graying by preserving endothelins and supporting healthy melanocyte activity. The study suggests luteolin's unique medicinal effect may be a promising candidate for addressing age-related hair graying.
A team of researchers from Penn State and the University of California, Irvine, have proposed a novel theory on the molecular basis underlying human scalp hair growth. They suggest that long scalp hair initially evolved to protect early human ancestors in equatorial Africa from intense heat and solar radiation.
Research found that intermittent fasting inhibits hair growth in mice by causing oxidative stress on stem cells. A clinical trial showed a similar effect in humans, with a 18% reduction in hair growth speed.
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A study suggests that low doses of the commonly prescribed hair loss treatment minoxidil are safe and effective for regrowing hair in most breast cancer patients. The researchers found that all participants who took a low dose of oral minoxidil saw improvements in hair growth or stabilization within three to six months.
Researchers at Yokohama National University found that cinnamic acid activates oxytocin receptor expression, increasing hair growth gene expression in human dermal papilla cells. The compound showed a similar hair growth effect to oxytocin, with a 1.25-fold increase in hair shaft-like structures.
A study led by Leopold Eckhart found that the genetic programme controlling keratinized claws originated in a common ancestor of humans and frogs. The research team used the tropical clawed frog as an experimental model and discovered that important hair components, including keratins, share similarities with human hair.
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Researchers at UNIST have unveiled a new principle of motion in liquid crystals, where objects can move in a directed manner by changing their sizes periodically. The discovery has far-reaching implications for the development of miniature robots and advances research in complex fluids.
Researchers at Rensselaer Polytechnic Institute have successfully created hair follicles in human skin tissue using 3D-bioprinting techniques. This innovation has potential applications in regenerative medicine, drug testing, and understanding the complex interactions between skin and topical products.
A new study has identified four genetic variants associated with the direction of human scalp hair whorls, revealing a polygenic inheritance pattern. The findings may help unravel biological processes related to abnormal neurological development.
Researchers at Northwestern University have discovered a way to soften stiff hair follicle stem cells, enabling them to grow hair again. By boosting the production of microRNA-205, they promote hair growth in both young and old mice, offering potential for human hair regrowth.
A new study published in the American Journal of Epidemiology found that chemical hair straighteners may affect a person's ability to become pregnant. Black and Hispanic individuals were more likely than other racial and ethnic groups to use these products, leading to a slight reduction in fertility rates.
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Researchers found that melanocyte stem cells, responsible for hair color, lose their ability to mature and maintain hair color as people age due to getting stuck in the skin. The study showed that these 'stuck' cells cease regenerative behavior when they're no longer exposed to WNT signaling, leading to graying and loss of hair color.
Researchers from Yokohama National University successfully generated hair follicles in cultures using organoid cultures. The study demonstrates the potential of hair follicle organoids for understanding hair follicle development and regeneration, as well as evaluating drugs for treating hair loss disorders.
A recent study published in PLOS Global Public Health found a correlation between perceived stress and hair cortisol concentration in Mexican and Icelandic women. The research suggests that cortisol levels, often associated with stress, can be detected in an individual's hair.
Researchers at the University of California, Irvine have identified SCUBE3 as a potential therapeutic treatment for androgenetic alopecia. The study found that dermal papilla cells produce activating molecules to promote new growth, which are reduced in people with hair loss.
Researchers at the Salk Institute have identified an unexpected molecular target of a common treatment for alopecia, a condition where the immune system attacks hair follicles. They found that glucocorticoid hormones instruct regulatory T cells to activate hair follicle stem cells, leading to hair growth and regeneration.
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A new study suggests that a nutraceutical supplement may improve hair growth and quality in perimenopausal, menopausal, and postmenopausal women. Researchers found significant increases in mean total hair counts and global hair quality improvements with few side effects.
A new microneedle patch containing cerium nanoparticles has been designed to combat both primary causes of baldness: oxidative stress and insufficient circulation. The patch showed faster hair regrowth in a mouse model compared to a leading treatment.
Daily use of high-dose biotin supplements among US adults has steadily increased since the early 2000s, with most consumers using these products for hair and nail growth. The study's findings suggest a growing interest in biotin as a supplement to support overall health.
A detailed molecular atlas of skin cells has been created, revealing over 50 different cell types and new variations of cell types. The study uncovers how cells are coordinated during hair growth and rest, providing vital knowledge on the flexibility of the skin.
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Using 3D printing, researchers have successfully grown human hair follicles in a lab dish, paving the way for new hair restoration treatments. The breakthrough could lead to more effective hair growth drugs and increased accessibility of robotic hair restoration surgery for women and men.
A team of researchers at NYU Langone Health has successfully regrown hair strands on damaged skin by stimulating fibroblasts to secrete collagen through the sonic hedgehog signaling pathway. The study offers new hope for treating hair loss and may lead to the development of more effective drugs.
Researchers developed a flexible, wearable photostimulator that speeds up hair growth in mice, achieving significantly faster hair regrowth and wider regrowth areas compared to untreated or minoxidil-injected mice.
Researchers discovered a novel mechanism of action for an immunosuppressive drug that promotes human hair growth and reduces hair loss. A compound targeting the same mechanism has shown similar effects in promoting hair growth without side effects.
A study found that a drug originally designed to treat osteoporosis enhances human hair growth by inhibiting SFRP1, a key protein that regulates Wnt signalling. This new agent, WAY-316606, shows promise in promoting hair growth without the side effects of existing treatments.
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The Endocrine Society Clinical Practice Guideline examines causes and treatments for hirsutism, a condition where women experience unwanted hair growth. The guideline recommends testing for polycystic ovary syndrome (PCOS) and other underlying health problems in all women with unwanted dark or coarse hair.
Researchers discovered that all hairs can communicate with each other and grow in coordination across the entire body, regulated by a single molecular mechanism. This finding could lead to new treatments for human baldness and unwanted hair growth.
Two studies suggest that aging of hair follicle stem cells may contribute to hair thinning. The research found that accumulating DNA damage and changes in key genes affect HFSCs, leading to miniaturized and reduced hair follicles.
Researchers at Columbia University Irving Medical Center found that inhibiting the Janus kinase (JAK) family of enzymes promotes hair growth in mice and human hair follicles. The study suggests that JAK inhibitors, approved for blood diseases and rheumatoid arthritis, could be used to restore hair growth in humans.
A team of scientists in Germany and Switzerland have identified the fungus Exidiopsis effusa as the cause of hair ice. The researchers found that the fungus enables the ice to form thin hairs, which are stabilized by a recrystallisation inhibitor provided by the fungus.
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A new study reveals that macrophages, a type of immune cell, play a crucial role in activating hair growth by surrounding and activating skin stem cells. This discovery may lead to the development of novel treatment strategies for hair loss in humans.
Researchers found that propolis, a substance from honeybee hives, encourages hair growth in mice by increasing special cells involved in the process. The study suggests that propolis' anti-inflammatory compounds could help treat balding conditions.
Scientists have discovered that changes in the hair growth cycle affect fluctuations in the thickness of underlying fat tissue, allowing skin to regulate fat production. This breakthrough could lead to topical creams that 'pause' fat cell growth, treating obesity and hair loss.
USC scientists have discovered the role of Wnt7b in activating hair growth and reducing baldness. The study's findings could lead to new therapeutics for various human diseases, including skin regeneration for burn patients and skin cancer.
A new study suggests manipulating the Wnt/B-catenin signaling pathway can prompt hair growth in dormant hair follicles. The team also found that this pathway is normally active in non-hairy regions of the skin, suggesting potential therapeutic targets for unwanted hair growth and skin cancer.
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Scientists discovered that a prostaglandin called PGD2 and its derivative inhibit hair growth, targeting GPR44 as a promising therapeutic target for androgenetic alopecia. Elevated PGD2 levels were found in the bald scalp tissue of men with male pattern baldness.
Researchers have found that examining the chin and upper/lower abdomen is an accurate and minimally invasive way to screen for excessive hair growth in women, which can be up to 80% effective. This method has significant implications for diagnosing PCOS and related health risks such as insulin resistance, diabetes, and heart disease.
Yale scientists identify adipose precursor cells as key players in triggering hair growth. These cells produce PDGF molecules necessary for producing hair growth in mice. The study offers a promising avenue for developing new treatments for male pattern baldness by targeting these stem cells and signals.
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Researchers have discovered a chromosomal mutation responsible for a very rare condition called CGH, which causes individuals to grow excess hair on their bodies. The study found that the insertion of chromosome 5 into the X chromosome appears to turn on a gene, likely SOX3, leading to excessive hair growth.
Researchers at UCLA and the Veterans Administration may have accidentally discovered a solution to regrow hair by blocking a stress-related hormone, according to an article published in PLoS One. The compound, astressin-B, induced long-term hair growth in chronically stressed mutant mice through a short-duration treatment.
Researchers discovered that TRPV3 plays a crucial role in regulating hair growth and skin health. The protein's activation leads to the release of TGF-alpha, which stimulates EGFR, forming a positive signaling loop.
A new study from Children's Hospital Boston finds that TRPV3 is a key regulator of skin and hair growth, leading to thinner, less intact skin when knocked out. The researchers suggest that stimulating TRPV3 activity could lead to new treatments for skin conditions, hair growth, or unwanted hair growth.
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A team of investigators has identified a new gene, APCDD1, which causes progressive hair loss beginning in childhood. The discovery provides insight into the process of hair follicle miniaturization, shared with male pattern baldness, and may lead to non-hormonal treatments.
The study provides the first experimental evidence of how individual carbon atoms are added to growing nanotubes. The rotation proceeds in discrete steps, resembling the halting motion of a mechanical clock's second hand, with approximately 24 steps per rotation.
A study found laser therapies to be safer when used separately, with more effective leg hair removal. Alexandrite lasers showed long-term efficacy, but caused higher pain severity and hyperpigmentation compared to Nd:YAG lasers.
Researchers found clumps of previously-unreported callus hairs growing in mature apples, which may impact commercial growers' storage strategies. The presence of these hairs could reduce the efficiency of gas transport through fruit, leading to internal browning.
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Researchers at the University of Bonn have identified a gene responsible for Hypotrichosis simplex, a rare hereditary form of hair loss. The study's findings offer new hope for developing targeted therapies for various forms of hair loss.
A recent study from Rockefeller University has discovered the protein NFATc1, which regulates hair growth and maintains stem cell potency. The research suggests that these stem cells do not need prolonged resting periods to maintain their abilities.
A large study of 188 women found that nearly 55% with minimal unwanted hair growth had an androgen excess disorder, primarily polycystic ovary syndrome (PCOS). Women with PCOS often struggle with menstrual irregularities, skin problems, and excess weight.
Penn researchers have isolated stem cells in adult mice responsible for hair growth, leading to the development of potential treatments. The findings also hold promise for burn treatments, where current skin grafting methods fail to generate hair growth.
Scientists at the University of Michigan Medical School have discovered that ß-catenin can induce new hair growth in adult hair follicles. The study found that brief activation of ß-catenin in telogen-phase hair follicles is sufficient to initiate the anagen phase, leading to new hair growth within 15 days.
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Researchers found that brief activation of beta-catenin in resting hair follicles can stimulate complex changes leading to normal hair growth. The discovery may hold potential for inducing hair growth, but caution is needed due to risks of uncontrolled beta-catenin activity.
A newly discovered protein called desmoglein 4 (DSG4) holds cells together as they change into different types of hair follicle cells. The gene's absence leads to thin, sparse hair that breaks easily in people and mice, highlighting its potential role in treating excessive or absent hair growth.
Research reveals US boys are reaching puberty earlier than in past years, with average ages of pubic hair growth and genital development being significantly lower. This could have implications for testicular cancer risk, sex education, and psychosocial challenges.