A new study published in Cell Metabolism found that a low-protein, amino acid-supplemented 'longevity diet' improved cardiometabolic markers and reduced frailty and fat mass in mice. The diet was associated with longer healthy lifespan and better metabolic health in both mice and humans.
SourceUniversity of Southern California·JournalCell Metabolism·TypeExperimental study·DateJun 23, 2026
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Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
A new study by UC San Francisco reveals that aging lung tissue can lead to catastrophic immune dysregulation, causing elderly individuals to become severely ill. The research suggests that targeting the damaged spiral of inflammaging could provide a promising therapeutic target for treating age-related respiratory diseases.
SourceUniversity of California - San Francisco·JournalImmunity·DateMar 27, 2026
A team at The University of Osaka has identified a signaling molecule called FGFR3 and a pathway called CREB as key in regulating bone growth. Cells carrying the genetic mutation associated with achondroplasia accumulate in the resting zone and show abnormal behaviors, which included abnormal patterns of division and migration.
SourceThe University of Osaka·JournalNature Communications·TypeExperimental study·DateFeb 26, 2026
Scientists found that tumor-promoting fibroblasts attract nerve fibers through a vicious cycle of signaling and neurotransmitter release. This cycle promotes pre-cancerous growth and pulls in more nerve fibers, leading to a self-reinforcing loop. Disrupting this cycle may lead to new therapies for pancreatic cancer.
SourceCold Spring Harbor Laboratory·JournalCancer Discovery·DateFeb 9, 2026
Scientists have found a way to effectively 'intercept' pancreatic cancer by targeting the KRAS and FGFR2 genes. This approach slows tumor formation and reduces the number of 'early versions' of cancer in the pancreas. Researchers believe this therapy could be a game-changer for patients with a family history of pancreatic cancer.
SourceCold Spring Harbor Laboratory·JournalCancer Research·DateApr 2, 2025
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SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers from Korea University have developed a groundbreaking technique to transform fibroblasts into mature cardiomyocytes, holding promise for regenerative medicine in treating cardiovascular disease. The method combines fibroblast growth factor 4 (FGF4) with vitamin C to accelerate cell maturation and enhance function.
SourceKorea University College of Medicine·JournalExperimental & Molecular Medicine·TypeExperimental study·DateDec 24, 2024
A new study found that fibroblast growth factor 21 (FGF21) is an independent predictor of all-cause mortality in older adults. The Polsenior2 study revealed that middle and high FGF21 levels were associated with increased mortality risk, particularly when adjusted for age, co-morbidities, and blood parameters.
SourceImpact Journals LLC·JournalAging-US·TypeNews article·DateOct 17, 2024
A new study reveals FGF18 as a key inducer of hepatic stellate cell proliferation and liver fibrosis. FGF18 levels are dramatically elevated in fibrotic livers, and its overexpression induces liver fibrosis in mice.
SourceToho University·JournalNature Communications·TypeExperimental study·DateOct 9, 2023
Researchers have discovered that embryonic stem cells are guided by a complex interplay of signaling molecules to determine their cell type. The study found that fibroblast growth factor (FGF) acts as an antagonist of the signal molecule BMP, influencing cell differentiation and fate.
SourceMax Planck Institute of Molecular Physiology·JournalBiology Open·TypeExperimental study·DateSep 19, 2023
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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers found that dietary saturated/trans fats, but not cholesterol, can trigger hepatic angiogenesis and lymphangiogenesis in mice, leading to the promotion of hepatic tumors. This process is driven by the JNK-HIF1α-VEGF-C axis.
SourceShinshu University·JournalLiver Cancer·TypeExperimental study·DateDec 7, 2022
Researchers found that severe asthma patients produce growth factors that block corticosteroids from working, leading to frequent breathing problems. This discovery may lead to new treatments targeting these growth factors to improve outcomes for patients with severe asthma.
SourceRutgers University·JournalScience Translational Medicine·TypeObservational study·DateMay 30, 2022
Researchers discovered that a hormone called FGF21 suppresses alcohol consumption in primates by altering neural transmission in the brain. This finding provides a mechanism for a liver-to-brain endocrine feedback loop to protect the liver from damage and may lead to potential treatment options for alcohol use disorder.
SourceCell Press·JournalCell Metabolism·TypeExperimental study·DateFeb 1, 2022
Biologists at St Petersburg University studied mechanisms of regeneration of marine animals and found that suppression of FGF protein activity disrupts the ability of Alitta virens to restore lost body segments. Similar proteins are found in humans, suggesting potential therapeutic approaches for regenerative medicine.
SourceSt. Petersburg State University·JournalGenes·DateJun 24, 2021
The study, published in Genes and Development, reveals the role of signaling pathways in regulating cell behavior, including proliferation, death, and migration. The research team identified new signaling outputs that function independently of established FGF signal transduction pathways, particularly in cell adhesion.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalGenes & Development·DateNov 11, 2020
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DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
Researchers found that fibroblast growth factor 1 repairs damaged perineuronal nets in the brain, a critical response required for sustained diabetes remission. The discovery sheds light on the intricate biology of the brain's response to the protein and may lead to more effective diabetes treatments.
SourceUniversity of Washington School of Medicine/UW Medicine·JournalNature Metabolism·DateSep 7, 2020
Scientists at CNIC discover a system providing cells with positional information about their location in developing organs. The study shows that malfunctioning of this system causes congenital malformations and may explain the effects of thalidomide, a drug inducing limb defects.
SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalScience Advances·DateJun 3, 2020
Researchers have discovered that physical forces, such as centrifugal force, play a crucial role in enhancing cell-to-cell attachment and increasing tissue stiffness during embryonic development. The study reveals that the FGF receptor/Erk2 signaling pathway is essential for this process.
SourceNational Institutes of Natural Sciences·JournalCell Reports·DateMar 18, 2020
The study reveals how fibroblast growth factor 23 (FGF23) signals to cells through its receptor and alpha-Klotho, reversing previous conjecture on alpha-Klotho's anti-aging role. The findings also shed light on kidney disease leading to heart hypertrophy.
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalNature·DateJan 17, 2018
Research at Kanazawa University identifies FGF signaling as essential for gyri formation in the cerebral cortex, enabling large-scale neuron development and brain functions. The study uses a ferret model to analyze genome-level interactions, revealing the importance of FGF signaling in gyrus formation.
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Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers at the University at Buffalo have discovered a common genomic pathway that may be responsible for schizophrenia. By studying skin cells from four adults with schizophrenia, they found a dysregulated gene program that affects over 1,000 genes and can lead to the development of the disease.
SourceUniversity at Buffalo·JournalSchizophrenia Research·DateFeb 27, 2017
Researchers at Tokyo Institute of Technology identified fgf20a and fgf3/10a as major fibroblast growth factor ligands involved in fin regeneration. Fgf signalling acts directly on fin ray mesenchyme to form a blastema, promoting cell proliferation and tissue recovery.
SourceTokyo Institute of Technology·JournalDevelopment·DateAug 4, 2016
Researchers at Osaka University found that smoking habits change the levels of α-klotho and FGF-21 in blood serum, which are linked to aging. These changes suggest a metabolic disorder and may contribute to accelerated aging in smokers.
SourceOsaka University·JournalScientific Reports·DateOct 12, 2015
A new study found that people with depression have higher levels of a brain protein called FGF9, which can be a target for developing new antidepressants. The research also showed that artificially increasing FGF9 levels in rats led to depression-like behavior changes.
SourceMichigan Medicine - University of Michigan·JournalProceedings of the National Academy of Sciences·DateSep 8, 2015
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
UC San Diego researchers use a statistical tool to determine the optimal media composition for growing human pluripotent stem cells (hPSCs), reducing variability and improving reproducibility. The findings aim to create a standard for hPSC cultures, enabling laboratories worldwide to access consistent results.
SourceUniversity of California - San Diego·JournalScientific Reports·DateMay 5, 2015
Researchers have found that local implants of autologous adipose tissue-derived cells resulted in significant pain reduction and healing within two to seven weeks for all patients with long-lasting, non-healing digital ulcers. The treatment showed promise as an alternative to traditional therapies.
SourceCell Transplantation Center of Excellence for Aging and Brain Repair·JournalCell Transplantation·DateFeb 25, 2015
Researchers found that mice lacking specific vascular system proteins developed normally but healed poorly from injuries. Increasing FGF signaling may improve wound healing, while inhibiting it in the eye could help patients with age-related macular degeneration or diabetic retinopathy.
SourceWashU Medicine·JournalProceedings of the National Academy of Sciences·DateAug 18, 2014
Researchers found functional electrical stimulation can promote endogenous neural precursor cell proliferation and improve motor function in rats with acute cerebral infarction. The treatment also enhanced expression of basic fibroblast growth factor and epidermal growth factor.
SourceNeural Regeneration Research·JournalNeural Regeneration Research·DateApr 23, 2014
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Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers found that Noggin accelerates and increases the differentiation of neural precursors, outperforming basic fibroblast growth factor (bFGF). Noggin's greater effect was observed in inducing neural precursor differentiation from human embryonic stem cells.
SourceNeural Regeneration Research·JournalNeural Regeneration Research·DateSep 16, 2013
Researchers have identified fibroblast growth factor 18 (FGF18) as a predictive marker for poor overall survival in ovarian cancer patients. The study found that overexpression of the FGF18 gene is associated with enhanced tumor blood vessel formation and expression of cancer-promoting cytokines.
SourceJCI Journals·JournalJournal of Clinical Investigation·DateSep 9, 2013
Researchers found that basic fibroblast growth factor protects the spinal cord by reducing calcitonin gene-related peptide and acetylcholinesterase expression in damaged motor neurons. This suggests a potential therapeutic application for treating spinal cord injuries.
SourceNeural Regeneration Research·JournalNeural Regeneration Research·DateSep 5, 2013
Researchers have developed a new bio-mimicking therapeutic that can stabilize bFGF, allowing for its potential use in treating skin wounds and accelerating the healing process. The stable conjugate has been shown to function like normal bFGF to trigger the same signaling pathways involved in wound healing.
SourceUniversity of California - Los Angeles·JournalNature Chemistry·DateFeb 19, 2013
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Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
A study in Cell Communication and Signaling reveals an extensive interactome of over 500 novel interactions between SH2 domains and phosphotyrosine peptides. The researchers identified six general classes of SH2 domain specificity, which may control the selectivity of individual domains.
SourceBMC (BioMed Central)·JournalCell Communication and Signaling·DateSep 13, 2012
Researchers have developed a new and effective way to regrow blood vessels, potentially bypassing surgery and repairing damaged vessels through injection of a lipid-incased substance. This method has shown promise in treating chronic myocardial ischemia disease, affecting up to 27 million patients in the US.
SourceUniversity of Texas at Austin·JournalProceedings of the National Academy of Sciences·DateFeb 16, 2012
Scientists have developed a method to deliver growth factor to regrow blood vessels, which could lead to revolutionary heart disease treatment. The research, published in PNAS, uses a novel delivery system that increases the activity and stability of growth factor.
SourceUniversity of Pittsburgh·JournalProceedings of the National Academy of Sciences·DateAug 2, 2011
Patients with elevated FGF-23 levels had a higher risk of end-stage renal disease and death, even at early stages of chronic kidney disease. The association was found across different estimated glomerular filtration rates (GFR) categories.
Researchers at URMC discovered a defect in cellular pathways regulating bone formation at the stem cell level, leading to premature closure of skull sutures and craniosynostosis. This finding sheds light on the complex system controlling stem cell fate and has implications for understanding skeletal disorders and cancer.
SourceUniversity of Rochester Medical Center·JournalScience Signaling·DateMay 25, 2010
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
A team of researchers has created a new in vitro model for studying the effects of light on wound healing. They found that exposure to blue-violet light increases mitochondrial activity, cell proliferation, and growth factor secretion in human epidermal keratinocytes. These results suggest that blue light may be useful in enhancing epi...
SourceInternational Association for Dental, Oral, and Craniofacial Research·JournalJournal of Dental Research·DateMar 4, 2010
Researchers at Washington University School of Medicine found that a growth factor gene plays a critical role in palate development, suggesting a new target for preventing and treating cleft palate. The study's findings could lead to the development of drugs that activate or inhibit the gene to ensure normal palate growth.
SourceWashington University in St. Louis·JournalProceedings of the National Academy of Sciences·DateFeb 2, 2010
A new study reveals that nerve-cell transplants can promote nurturing growth factors, promoting the healing of an injured nervous system. The transplants helped brain-damaged rats fully recover their cognitive function, including learning and memory.
SourceAmerican Psychological Association·JournalBehavioral Neuroscience·DateDec 9, 2009
Sky & Telescope Pocket Sky Atlas, 2nd Edition
Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
Researchers at the University of Pittsburgh have identified an enzyme inhibitor that increases cardiac progenitor cells and influences heart development in zebrafish. The findings have broad implications for understanding heart development and improving treatments for damaged or diseased tissues.
SourceUniversity of Pittsburgh Schools of the Health Sciences·JournalNature Chemical Biology·DateJul 5, 2009
A study by University of Utah researchers reveals that interaction between Wnt and Fgf growth factor signaling pathways is crucial for proper collective cell migration. Proper division of labor between the two pathways enables cells to migrate directionally, but defects in these interactions may lead to cancer progression.
SourceUniversity of Utah Health·JournalDevelopmental Cell·DateNov 10, 2008
Fibroblasts, key cells in wound healing, transform into powerful contractile cells through a mechanical process. This new understanding could help prevent fibrosis and improve tissue engineering by controlling the rigidity of cell cultures.
SourceEcole Polytechnique Fédérale de Lausanne·JournalJournal of Cell Biology·DateDec 17, 2007
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Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
The Pourquié Lab has demonstrated the crucial role of fibroblast growth factor (FGF) in somitogenesis, a process required for vertebrae formation. The study successfully characterized and verified FGF signaling's importance during this process, providing new insights into the clock and wavefront explanation of somitogenesis.
SourceStowers Institute for Medical Research·JournalDevelopment·DateOct 30, 2007
University of Iowa researchers have discovered new genetic mutations associated with non-syndromic cleft lip and palate, a common form of the condition. The findings may eventually help clinicians predict a family's risk of having more children with the condition.
SourceUniversity of Iowa·JournalProceedings of the National Academy of Sciences·DateMar 5, 2007
The study found that activating hedgehog signals in adult mouse hearts increased blood vessel density, offering an alternative to invasive procedures. The researchers believe a drug treatment targeting hedgehog signaling could provide substantial benefit to patients with ischemic heart disease and myocardial infarctions.
SourceWashU Medicine·JournalGenes & Development·DateJun 15, 2006
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Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.
Researchers have identified a link between the fibroblast growth factor system and major depressive disorder, with those treated with SSRIs showing smaller changes. The study's findings offer new insights into the biological mechanisms underlying mood disorders and potential avenues for targeted therapeutics.
SourceUniversity of California - Davis Health·JournalProceedings of the National Academy of Sciences·DateOct 14, 2004
Researchers have discovered a chemical messenger called fibroblast growth factor 18 (FGF 18) that regulates bone development in growing embryos. FGF 18 appears to coordinate both the lengthening and hardening of bones, which may lead to new understanding of diseases such as achondroplasia and osteoporosis.
SourceWashU Medicine·JournalGenes & Development·DateApr 2, 2002
Researchers have found that PR39 promotes angiogenesis by blocking the degradation of a key transcription factor, HIF-1alpha. The newly formed vessels were fully functional in mice studies, offering a promising tool for treating coronary artery disease and peripheral vascular disease.
SourceBeth Israel Deaconess Medical Center·JournalNature Medicine·DateJan 4, 2000
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Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Researchers at Duke University have demonstrated that two naturally occurring growth factors significantly improved the ability of severed nerve fibers to reconnect with high accuracy. The study could lead to new strategies for improving peripheral nerve repair procedures in humans.