Advanced practice providers (APPs) have lower productivity compared to emergency department physicians, but no apparent impact on patient satisfaction and safety metrics. The study suggests that APPs can be effectively integrated into EDs with staffing models accounting for their lower productivity.
The NIH Platform Vector Gene Therapy (PaVe-GT) project uses AAV9 as a platform vector to develop gene therapy products for four rare diseases. The project aims to improve the delivery of therapeutic genes into target cells, paving the way for access to gene therapy for patients with difficult-to-treat conditions.
Military personnel with extensive occupational blast exposure showed significant differences in brain imaging measures, including increased cortical thickness and neural inflammation. The study provides insight into the functional and structural neuroimaging alterations occurring in this population.
A recent study published in Academic Emergency Medicine found that Black patients are more likely to experience restraint use in emergency settings compared to white patients. The study also identified higher rates of restraint among homeless patients and those with public insurance or no insurance.
A study published in Academic Emergency Medicine found that mobile smartphone technology can improve out-of-hospital cardiac arrest (OHCA) survival. The 'Staying Alive' app, which alerts trained responders to nearby cardiac arrest victims, was found to reduce response times and potentially improve outcomes.
A study projects that returning students likely started school this fall with significant academic losses due to extended school closures. The top third of students may have made gains in reading, but educators and policymakers must address the academic struggles of many students who fell behind academically.
Only 7% of US school districts in poorer, ethnic minority populations intend to reopen fully this academic year. The study highlights the disproportionate impact of the pandemic on people of color and their increased likelihood of being frontline workers, leading to a lack of trust in government responses.
A genotype-agnostic gene therapy for cystic fibrosis has shown promise in clinical trials, potentially treating the disease in any patient, independent of their underlying mutation. Challenges remain to be overcome, including developing effective drug delivery systems that can reach pulmonary epithelial cells at low doses.
A special issue on Integrative Palliative Care was published in JACM, featuring research from 11 countries on this new model of care. The issue highlights the potential value of greater mutual respect and exploratory collaborations between palliative medicine and integrative health communities.
Researchers developed a point-of-care GFAP assay that delivers results in minutes, outperforming the current FDA-cleared assay. The assay's diagnostic performance was significantly better than that of the S100B biomarker, validating its utility as a diagnostic marker for CT-detected lesions.
A breakthrough study using gene therapy to target the inner retina has prevented blindness in a mouse model of CLN3 Batten disease. The treatment led to significant survival of bipolar cells and preserved retinal function, according to researchers.
A recent study published in the Journal of Planning Education and Research found that demolishing dilapidated houses can lead to nearby property owners improving their own homes. The study examined changes to house conditions over time and found that properties near demolitions showed fewer signs of deterioration.
A study published in Academic Emergency Medicine found that only a few key signs and symptoms significantly change the likelihood of community-acquired pneumonia. The study suggests prioritizing high-value elements of the physical examination to improve diagnostic accuracy and antibiotic use.
Researchers advocate for a holistic approach to global resilience by integrating natural, human, social, built and financial capitals. The 'Five Capitals' framework aims to break down silos and anticipate risks more effectively.
A study published in Personality and Individual Differences found that women and people with insecure attachment styles tend to play hard-to-get more, while men pursue them. The researchers also discovered that avoidant individuals tend to use hard-to-get strategies as a self-protective mechanism.
The COVID-19 pandemic is having a disproportionate impact on environmental justice communities, who are already vulnerable to poor air and water quality, limited access to healthcare, and socioeconomic hardship. These disparities in health outcomes and mortality rates highlight the need for urgent attention and policy changes.
A recent study published in Academic Emergency Medicine identified common barriers to using risk stratification tools for evaluating pulmonary embolism in emergency departments. The study found that provider-level factors such as risk avoidance and lack of knowledge of the tools dominated as barriers, while inner-setting factors were i...
Academic emergency departments have a legal, historical, and ethical obligation to provide safe evaluation and care to anyone in need. The Federal Emergency Medical Treatment and Labor Act (EMTALA) prohibits EDs from turning away patients, ensuring access to medical screening and care for all 120 million ED visitors annually.
The Academic Emergency Medicine journal is making its latest COVID-19 research freely available in an easy-to-navigate online collection. New research will be added to the collection as soon as it is accepted and available.
A new study published in Telemedicine and e-Health highlights the effectiveness of telehealth in reducing depression, anxiety, and PTSD symptoms among COVID-19 patients. The study emphasizes the importance of mental health support, especially via telehealth, to maintain psychological well-being during the pandemic.
A new article provides guidance on allocating stockpiled ventilators to healthcare facilities during a severe pandemic, considering factors such as need assessment and access to vulnerable populations. The strategies outlined are crucial for state and local planners to make informed decisions under difficult conditions.
A recent survey found that most emergency physicians (over half of 1,074 respondents) encounter firearms at work annually, yet less than half feel confident in handling them. The study suggests that emergency physicians may benefit from educational interventions targeting firearms safety.
The Journal of International Marketing explores the impact of digital environments on international marketing, with research highlighting key trends and frameworks. Studies examine social media, global brand building, customer journeys, dark net markets, and more, shedding light on the latest developments in the field.
A major new study found that daily book reading by children improves their academic performance, with an average increase of 0.22 points on school tests. The study also discovered no significant benefits from reading newspapers, comics, or magazines.
Researchers propose a new path forward for adipose-based cell therapies in reparative medicine, focusing on patient safety and evidence-based medical practice. The FDA argues that autologous cellular therapies need to demonstrate safety and efficacy before marketing.
Researchers from Yale School of Forestry & Environmental Studies argue that the IPCC guidelines need improvement to accurately calculate and report greenhouse gas emissions. They suggest using satellite imagery and machine-learning tools to expedite quantitative synthesis and address data gaps.
A study published in Academic Emergency Medicine found that troponin testing for acute coronary syndrome (ACS) in selected elderly patients with nonspecific complaints (NCSs) may not be necessary due to a low diagnostic yield. The study revealed an elevated troponin in 20% of patients but only a 1.2% ACS rate.
A study published in Academic Emergency Medicine found that prolonged telemetry (over 12 hours) is a safe alternative to hospitalization for non-low-risk patients with syncope. The sensitivity of ECG monitoring is high, supporting the use of minimum 12-hour monitoring as a diagnostic tool.
A UK study found that poor sexual health affects women in diverse ways and is often overlooked by current intervention efforts. The research identified distinct groups at risk, including women with low interest in sex and those experiencing depression, alcohol or drug use. Tailored programs may be needed to address these vulnerabilities.
A pediatrician at Children's National Hospital wrote a 27-line poem inspired by her young patients' comments about vaccines. The poem, part of the 'Poetry and Medicine' series, aims to capture the optimism and resilience of children despite challenges. Dr. Sims hopes the poem will help build self-efficacy and resiliency in her patients.
Researchers developed an adeno-associated virus vector to deliver anti-pTau antibodies directly into the hippocampus of mouse models with CTE, reducing pTau levels across the CNS. The study suggests this strategy could be effective in humans and may offer a new treatment option for CTE.
A Chinese fossil specimen was misidentified as an ancient spider species, with experts at the University of Kansas using fluorescence microscopy to uncover its true nature as a heavily altered crayfish. The study highlights the potential for fossils to be intentionally or unintentionally misrepresented.
The Journal Healthcare Transformation: Artificial Intelligence, Automation, and Robotics explores the challenges and opportunities for integrating technology into consumer healthcare. A recent article found that five telemedicine companies provided nearly half of telemental health visits, highlighting the need for coordinated care.
A study published in Academic Emergency Medicine found that video discharge instructions in the emergency department lead to a clinically important reduction in acute otitis media (AOM) symptomatology. Children of parents who watched a five-minute video experienced less symptomatology compared to those with paper handouts.
A new study published in Journal of Neurotrauma found that frailty is a significant predictor of poor outcomes after traumatic spinal cord injury, particularly in patients younger than 75. The researchers identified frailty as a risk factor for adverse events, acute hospital length of stay, and in-hospital mortality.
A study published in Academic Emergency Medicine found that Focused Cardiac Ultrasound (FOCUS) can significantly lower the likelihood of pulmonary embolism (PE) diagnosis in ED patients with suspected PE and abnormal vital signs. The results suggest that FOCUS can be an important tool in the initial evaluation of these patients.
Scientists successfully induce pluripotency in adult cat cells, generating stem cells that can differentiate into various cell types. The breakthrough may lead to the development of cellular models for genetic diseases affecting domestic cats and similar human disorders.
A new study found a significant relationship between racial discipline disparities and academic achievement gaps in the US. The research, conducted by Stanford University and other institutions, analyzed disciplinary and achievement data for grades 3-8 across school districts nationwide.
A study published in New Space: The Journal of Space Entrepreneurship and Innovation models population growth, caloric needs, land use, and potential food sources to determine Mars' food self-sufficiency. A diet composed of plants, insects, and cellular agriculture can meet human nutritional requirements.
A multicenter randomized controlled trial confirms an electrical-first approach is more effective in restoring sinus rhythm and shortening ED length of stay. The study found that patients managed with this strategy were discharged within four hours at a higher rate than those receiving a chemical-first approach.
A new study published in Academic Emergency Medicine found that unexpectedness, health and social conditions, lack of support from family or friends, and structural issues like job market and affordable housing availability contribute to homelessness. The findings suggest gaps in current homeless prevention services and can inform futu...
A special issue of PhytoKeys highlights 23 newly described species from China's biodiversity hotspots, showcasing the country's unique flora and diverse microclimates. The discovery underscores the need for conservation efforts in these regions to counteract increasing anthropogenic disturbance and destruction.
NASA has implemented three initiatives to make it easier for small businesses to collaborate with the agency, including an annual Request for Information and Industry Day events. These efforts aim to increase commercialization of innovations and improve collaboration between NASA and the small business community.
The guidelines for managing severe traumatic brain injury continue to evolve as new evidence emerges, emphasizing the need for high-quality research and clinically applicable recommendations. Key challenges and goals for the future include generating more robust evidence and translating it into effective patient care.
Researchers used an optimized AAV9 vector to deliver the galactosylceramidase gene to a mouse model of Krabbe disease, improving clinical symptoms and prolonging median survival. The treated mice lived up to 150 days, compared to 41 days for untreated mice.
A study found that pay-for-performance programs can reduce access block but may also lead to discharges associated with return visits and admissions. The program's effectiveness depends on the inclusion of specific targets, such as admission time.
A study found that 9% of patients with acute pain conditions continued opioid use 3 months after discharge from the emergency department. Most patients used opioids to manage initial or new pain, not misuse. The study highlights the need for non-narcotic methods to treat acute pain and further research on chronic pain mechanisms.
A recent study by Washington State University researchers found that women and professionals outside of university settings are underrepresented in high-impact, peer-reviewed archaeology publications. The authors suggest that structural barriers, lack of time and resources, and limited opportunities contribute to this disparity.
Researchers have developed a novel CRISPR-based platform called SHERLOCK that enables the detection and quantification of plant genes. The platform is rapid, portable, and low-cost, with high multiplexing capability, making it an important tool for agriculture in detecting pathogens or pests and in plant breeding.
The global consumption of food and natural resources drives primate habitat loss and degradation, threatening species with extinction. Researchers suggest changing consumer habits, creating an environmental fund, and holding corporations accountable to mitigate the impact of commodities trade.
SourcePeerJ·JournalThe Journal of Agricultural Life and Environmental Sciences·DateJun 17, 2019
A study found that altering food order and offering substitutes lower in saturated fat can encourage healthier choices when shopping online. Participants who received these interventions chose products with less saturated fat than those with no intervention.
A study by Sophie Terp, MD, MPH, found nearly one in five EMTALA penalty settlements involved psychiatric emergencies. These cases were more costly and often associated with failure to stabilize than nonpsychiatric emergency cases.
A study published in Academic Emergency Medicine found that half of syncope patients undergo CT head scans, yielding a diagnostic rate of 1.2% to 3.8%. The authors caution against indiscriminate use and recommend future studies to develop a prediction tool for optimal CT head use.
A study found a high rate of metabolic syndrome among elderly individuals aged 60-100 years. Three simple measures - waist diameter, waist circumference, and neck circumference - were predictive of metabolic syndrome in both men and women.
A new CMP-fusion strategy called CRISPR-chrom enhances CRISPR-Cas9 genome editing efficiency, especially at previously difficult-to-target sites. The approach demonstrates a substantial increase in CRISPR-Cas9 activity with no notable increase in off-target effects.
A study found a significant increase in high-grade dysplasia and esophageal adenocarcinoma among patients with Barrett's esophagus over the past 25 years. The prevalence of these conditions increased despite a decrease in BE length, highlighting the importance of careful examination during index endoscopy.
A study published in Academic Emergency Medicine found no association between FQHC access and lower ED use rates among uninsured and Medicaid-insured patients. The study suggests investigating additional intervention points beyond primary care access to reduce ED overuse in vulnerable populations.
A study published in Academic Emergency Medicine confirms that patients treated with naloxone for opiate overdose can be safely discharged from the emergency department after one hour. The study found minimal risk of adverse events and suggests the St. Paul's Early Discharge Rule as a useful predictor of high-risk patients.
PhD students from underrepresented minority groups publish more research when their institutional culture is welcoming and sets clear expectations. Black students face challenges due to negative experiences in white settings, but these are mitigated by a sense of preparedness and belonging.
A new genus and species of ceratosaurian, Saltriovenator zanellai, has been discovered in the Lower Jurassic of Italy, dating back over 25 million years. The specimen is the world's largest predatory dinosaur and features a unique combination of ancestral and advanced anatomical features.