Articles tagged with Academic Journals
Researchers used an optimized AAV9 vector to deliver the galactosylceramidase gene to a mouse model of Krabbe disease, improving clinical symptoms and prolonging median survival. The treated mice lived up to 150 days, compared to 41 days for untreated mice.
A study found that 9% of patients with acute pain conditions continued opioid use 3 months after discharge from the emergency department. Most patients used opioids to manage initial or new pain, not misuse. The study highlights the need for non-narcotic methods to treat acute pain and further research on chronic pain mechanisms.
A recent study by Washington State University researchers found that women and professionals outside of university settings are underrepresented in high-impact, peer-reviewed archaeology publications. The authors suggest that structural barriers, lack of time and resources, and limited opportunities contribute to this disparity.
Researchers have developed a novel CRISPR-based platform called SHERLOCK that enables the detection and quantification of plant genes. The platform is rapid, portable, and low-cost, with high multiplexing capability, making it an important tool for agriculture in detecting pathogens or pests and in plant breeding.
The global consumption of food and natural resources drives primate habitat loss and degradation, threatening species with extinction. Researchers suggest changing consumer habits, creating an environmental fund, and holding corporations accountable to mitigate the impact of commodities trade.
A study found that altering food order and offering substitutes lower in saturated fat can encourage healthier choices when shopping online. Participants who received these interventions chose products with less saturated fat than those with no intervention.
A study published in Academic Emergency Medicine found that half of syncope patients undergo CT head scans, yielding a diagnostic rate of 1.2% to 3.8%. The authors caution against indiscriminate use and recommend future studies to develop a prediction tool for optimal CT head use.
A study by Sophie Terp, MD, MPH, found nearly one in five EMTALA penalty settlements involved psychiatric emergencies. These cases were more costly and often associated with failure to stabilize than nonpsychiatric emergency cases.
A study found a high rate of metabolic syndrome among elderly individuals aged 60-100 years. Three simple measures - waist diameter, waist circumference, and neck circumference - were predictive of metabolic syndrome in both men and women.
A new CMP-fusion strategy called CRISPR-chrom enhances CRISPR-Cas9 genome editing efficiency, especially at previously difficult-to-target sites. The approach demonstrates a substantial increase in CRISPR-Cas9 activity with no notable increase in off-target effects.
A study found a significant increase in high-grade dysplasia and esophageal adenocarcinoma among patients with Barrett's esophagus over the past 25 years. The prevalence of these conditions increased despite a decrease in BE length, highlighting the importance of careful examination during index endoscopy.
A study published in Academic Emergency Medicine found no association between FQHC access and lower ED use rates among uninsured and Medicaid-insured patients. The study suggests investigating additional intervention points beyond primary care access to reduce ED overuse in vulnerable populations.
A study published in Academic Emergency Medicine confirms that patients treated with naloxone for opiate overdose can be safely discharged from the emergency department after one hour. The study found minimal risk of adverse events and suggests the St. Paul's Early Discharge Rule as a useful predictor of high-risk patients.
PhD students from underrepresented minority groups publish more research when their institutional culture is welcoming and sets clear expectations. Black students face challenges due to negative experiences in white settings, but these are mitigated by a sense of preparedness and belonging.
A new genus and species of ceratosaurian, Saltriovenator zanellai, has been discovered in the Lower Jurassic of Italy, dating back over 25 million years. The specimen is the world's largest predatory dinosaur and features a unique combination of ancestral and advanced anatomical features.
A study published in Academic Emergency Medicine finds that children and adolescents who survive firearm injuries have increased long-term mortality rates compared to those who survive nonviolent trauma. The study identifies socioeconomic disparities as a key factor in these disparities.
A screening tool can identify child sex trafficking victims presenting with high-risk health complaints in a pediatric emergency department. The study suggests that this tool presents minimal risk of harm and does not require significant extra time or resources.
The newly described fossil, Mirarce eatoni, is the most complete enantiornithine bird skeleton found in North America, providing insights into the evolution of flight. Its unique features, including quill knobs and a deeper keel on its sternum, indicate that it was a strong flier.
A recent study published in Academic Emergency Medicine demonstrated that long-term follow-up in a trauma patient population is feasible. The study used established contact strategies and various interview locations to track hard-to-reach populations. Researchers suggest exploring newer methods of contacting participants through techno...
The new law allows investigational stem cell treatments for patients with certain severe chronic diseases or terminal illnesses, sparking debate over increased access vs. unproven treatments.
A brief assessment of emergency department (ED) threat perceptions can identify patients at risk for developing cardiac-induced PTSD. The study developed a seven-item measure to assess subjective feelings of helplessness or lack of control in ED patients evaluated for acute coronary syndrome.
A new open-source electronic husbandry repository has been developed to manage zebrafish colonies, capturing demographic metadata and tracking fish mortality and fertilization. The cloud-based system is accessible via an everyday smartphone, enhancing reproducibility in science.
Professor Anita McGahan received the inaugural Education Impact Award from the Strategic Management Society for her exceptional contributions to quality and innovation in teaching strategic management. The award acknowledges her dedication to improving teaching skills and empowering others through high-quality materials.
Researchers developed innovative business models for space-related start-ups, including DIT Space, which commercialized satellite images and created competitive advantages. The study highlights the growth of space entrepreneurship worldwide, with a focus on Central America.
The RAC's elimination would shift review responsibility to local Institutional Biosafety Committees. The new approach aims to reduce redundancies between FDA and RAC roles in human gene therapy.
A new study found unpredictable and potentially harmful levels of higenamine in US weight-loss and sports/energy supplements, urging consumers to use caution. The researchers call for independent testing and certification of dietary supplements to minimize adverse health effects.
A new study published in Academic Emergency Medicine finds that risk adjusting for race and poverty improves the apparent performance of hospitals treating large numbers of nonwhite or poor patients. The study's lead author recommends including sociodemographic adjustment in payment models to prevent harm to vulnerable populations.
The 3.4 billion year old Strelley Pool microfossils had chemical characteristics similar to modern bacteria, supporting a biological origin and ranking them amongst the world's oldest microfossils. The analysis also shows that these ancient fossils have survived extreme conditions over the last 3.4 billion years.
A study found significant improvement in cone function and no abnormalities in treated eyes for up to six years. The treatment used an AAV5 vector delivered a CNGA3 gene therapy, offering hope for treating genetic blindness.
A new study shows that a single injection of AAVB1-GAA gene therapy prolonged survival and improved enzyme activity in a mouse model of Pompe disease. The therapy also targeted the respiratory system, improving ventilatory measures.
A study of 230 family SMEs found that involved boards are crucial for innovation, with strategic involvement driving value creation. The researchers highlight the importance of knowledge, competences, and capabilities of board members in promoting entrepreneurial attitudes.
A new study by Anglia Ruskin University finds that watching short films set in natural environments can improve body appreciation, while urban settings have no effect. This suggests a potential low-cost solution for promoting healthier body image, especially for those with limited access to real natural environments.
Addgene has made over 100,000 CRISPR plasmids available to laboratories worldwide, democratizing genome editing research. This global access has enabled the advancement and flourishing of CRISPR technology.
A new study reveals significant differences in post-concussion symptom severity and length of recovery between male and female college athletes. Notably, female athletes who used hormonal contraceptives experienced different outcomes compared to non-users, suggesting a potential impact on concussion recovery.
A recent review article emphasizes the urgent need for more clinical research, data, and prognostic models on traumatic brain injury in older adults. The lack of geriatric-specific TBI guidelines presents barriers to optimal care, and the authors discuss issues related to neurocritical care, neurosurgical management, and rehabilitation.
A study published in Academic Emergency Medicine found that training on synthetic and live tissue models did not result in a difference in performance for five critical procedures. The results suggest that further study is needed to determine the effectiveness of simulation training for emergency medicine and trauma teams.
A multidisciplinary approach to identify and care for young women with ischemic stroke may lead to improved outcomes. The study proposes creating clinical decision rules, educational campaigns, and preventive strategies to address the unique challenges in this population.
The US space exploration program should focus on robotic sample recovery and human missions to Mars, according to Scott Hubbard, Editor-in-Chief of New Space. He highlights the benefits of this strategy, including offsetting costs through international partnerships.
A study published in Brain Connectivity found significant differences in functional architecture and interactivity of the default mode network in adolescent and young adult males with autism spectrum disorder compared to those without ASD. These findings could lead to the development of new imaging-based diagnostic markers for autism.
A new study published in Journal of Neurotrauma found that traumatic spinal cord injuries can lead to persistent changes in metabolism, blood flow, and oxygenation up to 7 days post-injury. This suggests that current clinical practices may not be sufficient to prevent ischemia-related damage.
A new study describes the 3D printing of Shape Memory Polymers to produce active meta-materials that can change shape and recover their original state when heated. The researchers demonstrate that these 4D structures can achieve large area changes of up to 200% within a programming and recovery cycle.
Researchers found berberine improves diabetic encephalopathy through the SIRT1/ER stress pathway in db/db mice, linked to better lipid metabolism and decreased fasting glucose. The compound also protects against central nervous system degeneration and cognitive impairment.
A randomized, double-blind study found that haloperidol reduces nausea and pain in patients with acute gastroparesis, suggesting it as a promising adjunctive therapy. The addition of haloperidol to conventional therapy is better than conventional therapy alone without side effects.
A new method successfully removes cellular material from human livers while retaining the three-dimensional structure and extracellular matrix components. The technique enables reseeding of these scaffolds with human cells, providing proof-of-concept for generating bioengineered liver grafts.
The article discusses a debate over Mars exploration strategies, with some experts proposing the relaxation of planetary protection policies to expand the search for life on Mars. Current robotic missions may be hindering the discovery of Martian life due to contamination concerns, but easing policies could lead to breakthroughs.
This special issue of the Journal of African American Studies marks 40 years since Prince went pro, featuring scholarly analysis of his groundbreaking debut album For You. The collection provides fresh perspectives on Prince's innovative approach to music production and control.
A new study suggests that primary care providers' failure to discuss sexual orientation and behaviors with MSM is a significant barrier to accessing PrEP. The researchers found that improved communication would allow for more open discussion about health risks and preventive interventions.
Scientists have successfully generated dopaminergic neurons in a non-human primate model using induced pluripotent stem cells (iPSCs) derived from adult marmoset monkeys. This breakthrough advances the use of marmosets as a model for Parkinson's disease, enabling the development of regenerative medicine approaches.
A study published in Academic Emergency Medicine found that integrating clinical decision support into electronic medical records decreases high-cost imaging utilization, especially among higher users. This standardizes care delivery and improves compliance with evidence-based guidelines.
Researchers developed two types of titanium implants with fine and coarse textures using electron beam melting and direct metal laser sintering. The study found substantial differences in mechanical testing results, including improved osseointegration and torsional properties for the fine-textured implants.
Researchers found significant dose-dependent changes in cortical neural networks after radiotherapy for brain tumors, affecting global network effects and cognitive processing.
The article presents Elon Musk's vision for a self-sustaining city on Mars, requiring significant improvements in transportation costs. The CEO of SpaceX discusses the advantages of using Mars as a hub for a multi-planetary species, including its planetary options and system architecture.
A study of 97 youth football players aged 9-13 found they experienced a total of 40,538 head impacts during four seasons. The number of impacts differed significantly depending on the player's age/weight level, suggesting all athletes should not be evaluated as one group when assessing head impact exposure and injury risk.
Researchers used extensive interviewing and focus group methods to explore asthma treatment goals. A three-step qualitative process identifies patient-relevant concepts, ranks them, and refines assessment questions for concept measurement. The study suggests assessing symptom improvement, medication access, medication use, and asthma k...
Industry experts examine the advantages of shifting data analytics to the cloud, including cost savings and improved management of analytics workloads. The panel discussion highlights the potential for companies to gain by moving their data analytics activities to the cloud, including more efficient use of IT resources.
A new study reveals that mild traumatic brain injury (mTBI) patients exhibit changes in brain connectivity that can aid in diagnosis and predict cognitive and behavioral outcomes. Resting-state functional MRI assessments can serve as a sensitive biomarker for early mTBI diagnosis and patient performance.
A new study of U.S. adolescents has found an association between metabolic syndrome and impairments in reading, attention, and working memory. The researchers found that treatment can control and reverse metabolic syndrome, which may help reduce cognitive effects.
A study published by Durham University found that earworms, or songs that get stuck in your head, tend to have faster tempos, common melodic contours, and unusual interval structures. The researchers also identified specific songs with these characteristics, including Bad Romance and Don't Stop Believing.
A comprehensive analysis of research published since 2000 found that schools with positive climates can narrow achievement gaps among students of different socioeconomic backgrounds. The study suggests that by promoting a positive climate, schools can decrease socioeconomic inequalities and enable more social mobility.
Researchers found that students and parents wrongly believed look-alike Smart Snacks were available in stores. This confusion may lead people to think the same brands meet similar nutritional standards. The study highlights the importance of distinguishing between packaged versions sold in schools and those in stores.