Articles tagged with Aging Populations
A large Japanese study found that maintaining a healthier profile with lower lifestyle and health risks can significantly lower dementia risk in people with one or no APOE ε4 alleles. However, individuals carrying two APOE ε4 alleles may require different preventive or therapeutic approaches.
A new study finds that immigrants who are socially integrated on some dimensions but not others experience worse health, particularly among minority groups. The 'acculturative discordance' phenomenon is associated with higher disability risks after age 65, affecting one in four adults aged 65 and older.
Dr. Mina Sedrak has been selected to co-lead the Cancer in the Older Adult Committee of The Alliance for Clinical Trials in Oncology, focusing on improving care and outcomes for older adults with cancer. As a leading expert on aging and cancer, Sedrak aims to expand research on this population and address their unique needs.
A recent study found that semaglutide, a widely used GLP-1 drug, slows down the accumulation of biological aging markers in adults with HIV. The treatment reduced chronic immune activation, visceral and ectopic fat, and reprogrammed certain cells, which may help explain its effects on multiple aging clocks.
A study found that 14 million workdays are lost annually due to menopause, while women rely on online misinformation for medical advice. The authors advocate for open conversation and inclusive approaches to combat stigma and support women's health during this transition.
Researchers found that impaired virtual reality path integration was closely tied to brain structure and biomarkers associated with neurodegeneration. This suggests that VR-based navigation errors may reveal hidden changes in the brain long before symptoms arise, making it a promising behavioral marker for preclinical Alzheimer's disease.
A new study projects that climate change will significantly increase the risk of heat-related cardiovascular disease in the US by 2050. The Pacific Northwest and Southern/Midwestern states are expected to experience the highest and steepest increases, respectively. Targeted interventions for vulnerable communities are crucial to mitiga...
Researchers developed a senolytic therapy using dasatinib and quercetin, which preserved disc structure and reduced inflammation, highlighting JUN signaling as a key pathway. This preclinical study provides evidence for a potential therapeutic strategy to slow disease progression in individuals with genetic susceptibility.
Older patients with accessible advance directives in electronic health records had 25% less potentially burdensome end-of-life care and 31% fewer hospital deaths compared to those without these directives. The associations were attenuated among patients with dementia and Black patients, highlighting the need for targeted research.
Researchers at UC Riverside have identified a key neural circuit, the locus coeruleus, which plays a central role in cognitive flexibility and adapting to new rules. Disrupting this circuit impairs the brain's ability to reorganize neural networks during complex decision-making.
A new study suggests that an earlier first sexual intercourse may be associated with a less favorable multidimensional aging profile, including shorter longevity and higher frailty. The researchers found that genetic differences in early sexual debut were linked to poorer health outcomes later in life.
Researchers at Kyoto University found that hospital restructuring improved local capacity for elderly hospital admissions and enabled more efficient bed management. The study suggests that reorganization can alleviate regional healthcare disparities in the elderly population.
A new analysis of police data reveals that one in 10 missing incidents among people with dementia results in serious harm. The study highlights the need for preventative action to keep people with dementia safe and finds that older age, night disappearances, and longer durations of absence are risk factors for harm.
A study published in JMIR Aging predicts early mobility decline in healthy adults aged 45 using a set of home-based measurements and AI. The researchers identified six essential factors, including age, muscle power, and diet, that accurately predict future mobility struggles.
A study published in Aging Cell found that reducing dietary fat or animal-based protein can reduce 'biological age' in older adults. After just four weeks, participants showed significant reductions in biomarker profiles indicative of improved health and aging outcomes.
A new study by University College London researchers found that regularly taking part in arts activities slows the pace of biological ageing. Participants who engaged in arts and cultural activities more frequently appeared to have a slower pace of ageing, comparable to those who exercised at least once a week.
A study reveals that S-1-propenyl-L-cysteine, a bioactive compound found in aged garlic extract, promotes inter-organ communication between fat tissue and the brain, enhancing muscle strength. Long-term administration of S1PC reduced frailty scores and increased skeletal muscle force in aged mice.
A study published in JAMA Network Open found that stronger, more stable, and less fragmented daily patterns of rest and activity are associated with slower physiological aging. The research suggests that these patterns may serve as potential targets for interventions to slow the aging process.
A three-year longitudinal study of 4,000 adults reveals that proactive engagement and self-agency can measurably improve brain performance across the lifespan. The study's findings challenge the notion that cognitive decline is an inevitable part of aging.
A recent study reveals that an individual's readiness to adopt smart technology is deeply tied to their specific experience within their home and community. Researchers identified specific clusters within the older population, ranging from tech-ready urbanites to those in more traditional or isolated residential settings.
Genomic Press launches Brain Health, a new peer-reviewed journal dedicated to the science of lifelong brain resilience, featuring research on glial plasticity and recovery from depression. The inaugural issue explores the intersection of fields including cognitive reserve, sleep, aging biology, nutritional psychiatry, and social sciences.
A new study highlights the importance of involving older people in technology design to ensure devices are useful, respectful, and culturally appropriate. Co-design helps build trust and ensures technologies support older people's autonomy and dignity.
Dr. Hannah Cabré has been appointed as an Assistant Professor and Director of the Aging, Gynecology, and Endocrinology Laboratory at Pennington Biomedical Research Center. Her research focuses on the role of female sex hormones in shaping nutrition, health, and performance across the lifespan.
A new study reveals that menopause causes profound and uneven transformations across the female reproductive system, rather than a uniform decline. The research identified molecular signals associated with aging detectable in blood, allowing for non-invasive monitoring and earlier detection of risks.
A new study reveals that over 75% of older adults have used complementary health approaches, including mindfulness, yoga, tai chi, acupuncture, and more. The study highlights the need for healthcare providers to discuss the risks and benefits of these therapies with their patients.
A study found that higher midlife cardiorespiratory fitness is strongly associated with later onset of chronic disease, lower overall disease burden, and longer life expectancy. Adults with higher fitness levels developed fewer chronic diseases and spent more years free from serious illness.
A new study reveals a strong link between extreme climate events and the incidence of heart disease among middle-aged and older adults in 157 Chinese cities. Exposure to extreme heat, cold, and precipitation increases the risk of cardiovascular disease, with higher BMI-related risks associated with temperature intensity and cold-induce...
Researchers found that younger mice had lower cancer spread, while middle-aged mice were more likely to experience aggressive melanoma. Middle-aged mice also had fewer immune cells called gamma delta (γδ) T cells, which help prevent cancer from spreading.
A study of over 1.27 million federal complaints found that older Americans and veterans receive slower responses than the general population, with a widening gap over time. The trend is particularly concerning for elderly residents in economically disadvantaged zip codes, who face the widest gaps in response times.
Research by Arizona State University professor Frank Infurna reveals a decline in middle-aged Americans' mental and cognitive health, with increasing loneliness, depression, and memory problems. Financial vulnerabilities, including income inequality and limited safety nets, contribute to these issues.
Researchers identified the misdirected immune response as a central driver of tissue degeneration in severe, rapid-aging disorders. By reducing this false alarm, they restored function across multiple biological systems, suggesting the body can cope with more DNA damage than assumed if inflammation is kept in check.
A new study by Lancaster University found that cognitive ability, education, and employment status are key factors influencing internet use among older adults, not age itself. The study analyzed data from over 6,000 people aged 50+ and found that most older adults in England regularly use the internet.
A major European study found that loneliness affects the memory of older adults, but does not speed up mental decline over time. Participants who reported high levels of loneliness performed worse on initial memory tests, but their ability to recall information declined at a similar rate as those with lower loneliness levels.
A Rutgers Health study reveals that neighborhoods with greater access to community amenities, services, and infrastructure can reduce the risk of dementia in older Chinese immigrants. The researchers found that individuals living in more cognitively supportive neighborhoods declined more slowly with age.
A new study by the Barcelona Supercomputing Center reveals that women's immune systems undergo more pronounced changes with age, leading to a greater susceptibility to autoimmune diseases. In contrast, men experience less extensive immune system changes, but are at higher risk for certain blood cancers.
A new study by the University of Eastern Finland highlights the challenges faced by older immigrants in Finland when seeking social and healthcare services. The study found that lack of language skills, incorrect diagnoses, and discriminatory practices hinder their access to employment and citizenship. Improving interpreter services, p...
A recent study published in Journal of the American Geriatrics Society found that individuals with higher optimism have a lower risk of developing dementia. After analyzing data from the Health and Retirement Study, researchers discovered a 15% lower risk associated with a one-standard-deviation increase in optimism.
Public long-term care insurance in China's pilot program cuts catastrophic health spending by up to 52%, shifting care away from costly medical interventions. This model offers a powerful alternative for value-based end-of-life care.
Researchers at NYU School of Global Public Health found that people living in neighborhoods with fewer social and economic opportunities have higher levels of CDKN2A RNA, a measure of cellular aging. This suggests that structural conditions may be biologically embedded and influence aging processes over time.
The Italian Society of Gerontology and Geriatrics has partnered with MDPI to publish its Journal of Gerontology and Geriatrics in open access. The journal, which was founded in 1953, will transition to a digital-only format starting with Volume 74, Issue 1 in March 2026.
The Alliance for Clinical Trials in Oncology is enrolling adolescent and young adult cancer patients in various trials, including genetic services and treatment studies. These trials aim to address longstanding gaps in care and improve outcomes for AYAs with cancer.
Dr. Rivera's exceptional clinical career is recognized for strengthening community-based health programs, leveraging technology to improve older adult care, and integrating age-friendly principles beyond specialty settings. She advocates for geriatricians as key partners in primary care, providing support to manage complex care needs.
A new study published in PLOS Medicine found that consistently meeting physical activity guidelines throughout middle age reduces women's risk of dying from any cause by half. The study, which tracked over 11,000 Australian women, also found strong benefits for cardiovascular disease and cancer mortality.
A new book by Swansea University researchers argues that attention impairments, rather than memory dysfunction, are a key aspect of dementia. The authors suggest that recognizing these changes could lead to earlier identification, improved diagnosis, and better care for those affected.
A study of 10,978 participants found that cooking at home at least once a week is associated with a lower risk of dementia. Novice cooks with few culinary skills saw a 70% reduction in risk, while skilled cooks still benefited from regular meal prep
Researchers found that penguins living in zoos with regular food access and limited physical activity age faster, but live longer than those in the wild. The study reveals a link between zoo conditions and accelerated aging mechanisms.
The study compares remaining life expectancy at age 75 for women and men in Sweden and Japan, finding that older Japanese individuals generally have lower mortality than Swedes. However, this difference is primarily observed among those receiving some form of elder care, with Japanese women expected to spend more years in elder care.
Older adults with and without Parkinson's disease have increased brain activity and muscle signals when recovering from balance disturbances. This makes it more difficult for them to recover their balance.
Experts will address critical issues in voluntary assisted dying and dementia, including community attitudes, Indigenous perspectives, and organ donation. The conference, open to the media and public, features over 130 presentations on VAD and its intersection with dementia.
Researchers created the most comprehensive single-cell atlas of epigenetic changes in the aging mouse brain, revealing how DNA methylation, genome structure, and gene activity change across brain regions and cell types. The atlas has already shown clear epigenetic differences between different age groups and allowed the development of ...
Researchers at the University of Gothenburg have identified a protein, ATF4, linked to increased metastasis and recurrence in lung cancer. The study reveals that older individuals' tumors are smaller and grow more slowly, yet more likely to have spread when detected.
Research found that Roseburia inulinivorans is positively associated with muscle mass and strength in both young and older adults. The study suggests that R inulinivorans may play a causal role in muscle strength, with notable increases in forelimb grip strength and larger muscle fibre size in mice treated with the bacteria.
A daily multivitamin may slow biological aging in older adults, with benefits seen in those with accelerated biological age. The study found slowing in all five epigenetic clocks, including those predictive of mortality, equating to about four months less biological aging over two years.
A new study models brain aging and resilience over the lifespan, uncovering individual factors that affect cognition and identifying potential biomarkers of healthy brain aging. Researchers are now incorporating diverse data, including social and lifestyle factors, to create a broader picture of the aging brain.
Research connects adolescent aggression to accelerated aging and higher body mass index by age 30. Early aggression alone does not predict faster aging unless it leads to ongoing relationship problems later in life.
Researchers have developed a painless skin patch that samples key immune cells from the skin, offering a new way to monitor immune health. The device detects inflammatory signals and collects immune cells without invasive procedures.
The THRIVE team is developing a PROSPR Intrinsic Capacity score to predict 20-year health outcomes, using wearable data, blood-based biomarkers, and health surveys. The score aims to enable accessible, scalable monitoring of aging and improve interventions.
A new study from Duke University Medical Center suggests that a simple blood test can accurately predict short-term survival in older adults by detecting specific piRNA molecules. Lower levels of these molecules are linked to longer survival, echoing patterns seen in simple organisms where reducing them can extend lifespan.
New research reveals that skeletal muscle retains a 'molecular memory' of repeated disuse, which differs between young and old muscles. Younger muscles show resilience, while older muscles become increasingly susceptible to atrophy. The study provides insights into how muscle responds to inactivity and its potential for recovery.
Researchers identified nine piRNAs linked to longevity, which could be detected through simple blood tests. The study suggests that these molecules may help predict survival and guide therapeutic targets for older adults.