Articles tagged with Aging Populations
Researchers found a progressive shift in RNA contents of sperm with age, potentially contributing to health risks of having kids later in life. The discovery may lead to improved fertility outcomes and diagnostic tools.
A new study found that shingles vaccination is associated with lower inflammation, slower epigenetic aging, and overall slower biological aging in older adults. Vaccination showed benefits even four years after the initial dose.
Research reveals structural brain changes in older adults affect ability to shift between tasks and update environmental information. These changes may lead to deficits in behavioral adaptability, emphasizing the importance of identifying age-related brain structure changes.
An 18-week study found that maintaining grip strength and chair-rise performance alongside weight loss was possible without a prescribed strength-training program, alongside improvements in biomarkers linked to metabolic and cognitive aging. A plant-forward diet featuring fresh lean pork supported healthy-aging markers in older adults.
A recent study by researchers at the University of California, Riverside, found that a specific brain region known as the caudate nucleus is strongly linked to physical strength in older adults. The discovery could help detect and prevent frailty before it begins.
The study found that women with two to three children tend to live the longest, while those with an above-average number of children have shorter lifespan. Pregnancies between ages 24 and 38 were also linked to more favorable aging patterns.
Researchers develop new framework to evaluate monetary value of QALY, adjusting for age and lifetime quality of life. Analysis yields key findings on cost-effectiveness of healthcare policies, highlighting benefits of promoting good health throughout life.
A recent genomic study by Dr. Mayana Zatz and colleagues reveals that Brazil's admixed population may hold the key to understanding exceptional aging. The study identifies over 8 million novel genetic variants in the Brazilian population, with potential protective mechanisms against age-related diseases.
A new study from Duke University found that even mild stress before surgery can lead to delirium, uncontrolled pain, and longer hospital stays in older adults. Over 40% of patients reported moderate to high distress levels similar to those with advanced cancer.
Researchers compared brains of stroke patients with healthy controls to reveal differences in language processing mechanisms. People with verbal speech processing issues from stroke have weaker processing of speech sounds than healthy participants.
A new study published in Neurology found that age does not impact neurological recovery after spinal cord injury, but older adults have poorer functional outcomes in tasks such as feeding, bathing, and mobility. The study also found a significant reduction in functional recovery with increasing age, particularly in those over 70.
A new study found that slower reaction time and lower response accuracy in cognitive tasks are associated with higher levels of frailty. The association can be detected in late midlife among individuals aged 57 to 70 years.
Researchers found that heat-inactivated Lentilactobacillus kefiri YRC2606 reduced age-related inflammation and improved immune function in mice. The strain exhibited anti-inflammatory effects by lowering levels of inflammatory cytokines and signaling proteins.
Research by Li-Mei Chen finds that digital tools provide measurable benefits for caregivers and persons living with dementia, improving self-efficacy, emotional well-being, and social connectedness. However, equity gaps remain due to limited access to culturally adapted and inclusive technologies.
A study by NYU Rory Meyers College of Nursing found that older, unpaid caregivers who used the internet more often felt less lonely and coped better with stress. The researchers analyzed data from over 3,957 participants ages 65 and older, and discovered a buffering effect: internet use reduced loneliness in caregivers with health issues.
Researchers argue that widely used proxies for aging may conflate genuine modifications with simpler effects on physiology. Targeting specific pathologies can extend lifespan without slowing aging process. Historically, increased human lifespan was primarily driven by reduced infectious disease mortality, not a fundamental slowing of a...
A new poll suggests that more than 80% of people over 65 drive at least weekly, but less than half have made a plan for when they can no longer drive safely due to health changes. Only 6% of older drivers have discussed their driving with a healthcare provider.
Researchers develop ex vivo treatment of blood stem cells with Rhosin, a RhoA inhibitor, to rejuvenate them and improve the production of healthy blood cells. This strategy targets the core of the ageing process, making blood stem cells more capable of regenerating and producing new healthy blood cells.
A novel study shows that US counties with limited digital tools, weaker support systems, and fewer healthcare resources exhibit poorer cognitive, mental, and physical health. The researchers found that counties with high resilience had significantly better outcomes, and that healthcare infrastructure is a key modifiable factor.
Regularly eating meals alone is associated with poorer diet quality and increased risk of weight loss and frailty among community-living adults aged 65 years and over. Social connections at mealtimes can influence appetite, dietary variety, and overall wellbeing.
A recent study found that multilingual individuals experience slower biobehavioral aging compared to monolinguals. The study analyzed data from 86,149 participants across Europe and showed that multilingualism is associated with a lower risk of accelerated aging.
A Baycrest study found that subtle features of speech timing, such as pauses and fillers, are linked to executive function and predict cognitive decline. The research uses artificial intelligence to analyze natural speech patterns for early detection of dementia.
Exercise promotes angiogenesis and lymphangiogenesis through molecular signaling pathways, enhancing vascular function and immune response. This process offers potential interventions to combat age-related decline and disease, including cardiovascular diseases, muscle atrophy, and metabolic disorders.
Researchers uncover tandem allosteric effect enabling efficient deacetylation of proteins by Sir2, a key enzyme for biological processes. This finding reveals new target for modulating Sir2, potentially leading to novel cancer treatments and therapeutic applications.
The $4 million gift from Jeff and Linda Moslow is supporting the Tufts Women's Health and Menopause Initiative, a unique academic collaboration between Tufts Medicine and the Friedman School of Nutrition Science and Policy. The initiative aims to advance clinical care, education, and research in women's health across the lifespan.
Research from Michigan Medicine uncovers connections between a longevity gene, behavior, and environment, suggesting that manipulating stress responses could extend life without downsides. Touch activates a circuit modulating signals to reduce the longevity effect of dietary restriction.
A team of researchers at Osaka Metropolitan University has successfully treated spinal compression fractures in rats using stem cells derived from adipose tissue. The study found that these cells can promote bone healing and regeneration, making them a potential solution for osteoporotic vertebral fractures.
A survey of 4,890 participants found that people are open to using home-care robots as long as they view them beneficially. Collaboration between users and developers is crucial for adoption, with emphasis on ethical considerations. Robots may play a significant role in addressing Japan's aging population and social healthcare challenges.
Researchers explore the link between senescent cells and metabolic diseases, highlighting potential treatments known as senotherapeutics. Senolytics, senomorphics, and senosensitizers are interventions aimed at eliminating or suppressing senescent cells to mitigate metabolic disease.
Huimin Zhang, a UC Riverside assistant professor, has received a $150,000 grant to study the role of HELIOS in epigenetic regulation of T cell aging and TFH cell differentiation. Her research aims to understand how aging affects the immune system and develop new vaccines and therapies to restore immune vitality in older adults.
Researchers at Ben-Gurion University find that CD4 T cells play a critical role in reducing aging by cleaning out senescence cells. They suggest tracking people in their 30s to assess the pace of aging and developing early interventions.
A study by the Gerald P. Murphy Cancer Foundation's Center for Exceptional Longevity Studies found that retaining gonad function can significantly impact frailty mortality risk. Male dogs with shortest testis exposure had high mortality risks, while those with longest gonad exposure showed no consequence of increasing frailty.
A recent study from the University of Georgia suggests that older adults who use smartphones, computers, and tablets are more socially engaged than their less tech-savvy peers. This increased social engagement is associated with better well-being and a longer, more fulfilling life.
Researchers analyzed blood samples from dogs in the Dog Aging Project and found that post-translationally modified amino acids are strongly linked to age, suggesting a promising indicator of physiological aging. The study also highlighted an important role of the kidney in the relationship between age and blood metabolites.
A recent study by Willa Granger examines the transformation of nursing homes in postwar America, tracing the development of the modern nursing home industry through the lens of the Americana Corporation. The research reveals how federal programs and corporate models reshaped eldercare, prioritizing scale and replication over community ...
Dr. Ana Daugherty, a cognitive neuroscientist with expertise in aging and Alzheimer's disease, joins Wayne State University's Institute of Gerontology as its new director. She will lead interdisciplinary collaboration, training for emerging scholars, and research on risk and resiliency in aging and dementia.
A study from the Norwegian University of Science and Technology found that older people tend to interpret ambiguous facial expressions as positive. The researchers discovered that this is due to adaptations in the locus coeruleus, a small organ at the bottom of the brain responsible for regulating alertness and attention.
A new study from Wake Forest University School of Medicine found that individuals living in socially vulnerable neighborhoods showed measurable differences in brain structure and function, including a thinner outer layer of the brain and white matter changes. These findings suggest that the environment in which people live can shape th...
A new study by the University of Surrey found that individuals with positive views on ageing are more likely to engage in vigorous physical activity. The research suggests that a positive outlook can act as a psychological buffer, helping older adults stay active despite health challenges.
The new centre supports multiple clinical trials in parallel, enabling comprehensive evaluations of organ health across physiological systems. It also provides hands-on training opportunities for healthcare professionals, bridging the gap between theoretical knowledge and practical application.
Research reveals that ovarian aging is not just about egg quality, but also the surrounding cells and tissues. The study found that eggs cluster in pockets surrounded by egg-free zones, which decline in density with age, influencing egg lifespan and maturation.
A recent analysis found that former inmates report worse health than non-incarcerated peers, even years after release. The study, published in the Journal of the American Geriatrics Society, suggests that clinicians consider screening for incarceration history and connecting patients to supportive services.
New traumatic brain injuries in older adults are associated with a higher risk of developing dementia. Research published in the Canadian Medical Association Journal found that TBI is linked to an increased rate of incident dementia, even when sustained in late life, and how this risk changes over time.
A large-scale international study found that creative experiences slow brain aging and promote healthier brain function. Creative activities such as music, dance, and video games were linked to 'younger' brain profiles, particularly in regions vulnerable to neurodegeneration.
Telomeres, which cap chromosomes, are inherited from parents in a parent-of-origin effect, with mothers contributing short telomeres and fathers long ones. This process is linked to cancer risk and aging, and researchers hope to study it further using human genome sequencing.
A National Science Foundation grant will support older adults in developing digital technology skills and embracing AI, with a focus on intergenerational storytelling. The project aims to strengthen AI literacy, social connectedness, and resilience among older adults, while cultivating responsible AI awareness in youth.
A team of researchers led by Dr. Manel Esteller has published a study on the longest-lived person ever recorded, Maria Branyas, who reached 117 years. The analysis reveals a fascinating duality: simultaneous presence of signals of extreme aging and healthy longevity. Despite signs of aging, Branyas had genetic characteristics associate...
A study of 1,620 participants aged 6-80 found that motor skills develop rapidly in children up to age 10, with adults reaching peak performance between 20-35 years old. Fine motor skills remain stable into old age, while gross motor and strength decline faster with age.
Researchers highlight NAD+ supplements as potential key to healthier ageing and disease prevention, but call for larger studies. Early trials report improvements in memory, movement, and metabolism.
A large-scale population study found that oxaliplatin benefits only younger stage III patients, with no added survival benefit for those over 70. The study suggests using an age threshold to make evidence-based choices about chemotherapy.
A new study reveals that population aging is the largest contributor to musculoskeletal disorders globally, accounting for approximately one third of countries and territories. The research highlights the need for targeted public health strategies and healthcare resource allocation to alleviate the burden of these disorders.
Researchers from Trinity College Dublin discovered that nanoplastics can interfere with brain energy production by disrupting the electron transport chain in mitochondria. This finding may have implications for understanding neurodegenerative diseases and learning/memory issues.
A study found that older adults are discontinuing benzodiazepines soon after hospital discharge, but many continue use for months, posing health risks. Researchers recommend targeting high-risk patients with deprescribing strategies to prevent chronic use.
Researchers developed standardized guidelines to diagnose and treat cemental tears, reducing misdiagnosis and improving patient outcomes. The consensus identifies key risk factors, diagnostic strategies, and treatment principles, empowering clinicians to recognize and manage this hidden threat more effectively.
A study by Dr. Esther Sternberg highlights the importance of social engagement, intellectual stimulation, purposeful activity, humor, and spiritual exploration in achieving exceptional cognitive and social functioning in advanced age. Dr. Reichlin's example challenges conventional assumptions about aging trajectories.
Researchers found that frail patients with residual intra-abdominal bacteria or fungi are at a higher risk of developing postoperative ileus and infections. The study suggests that incorporating frailty assessment and prehabilitation programs into surgical planning may help reduce complications.
Researchers at Tohoku University discovered a way to strengthen legs through daily etiquette, known as Rei-ho, which emphasizes slow and controlled movements. The study found that those who practiced Rei-ho for five minutes daily increased their knee extension strength by an average of 25.9%, compared to only 2.5% in the control group.
Researchers found that increased levels of EPS8 drive pathological protein aggregation and neurodegeneration in worms and human cell models. By reducing EPS8 activity, they prevented toxic protein accumulation and preserved neuronal function.
A new study by Concordia researchers finds that chronic benzodiazepine consumption impacts sleep quality in older adults, leading to poorer sleep architecture and brain oscillation activities. The study suggests that these drugs may worsen cognitive functions already affected by aging.
Hebrew SeniorLife's 108 Centre Street affordable senior housing building has achieved Phius Certification for its high-performance, energy-efficient design. The seven-story building provides 54 affordable apartments for seniors and advances sustainable, healthy housing in Greater Boston.