Researchers identified a molecular mechanism linking early-life environments with memory by activating AP-1, which regulates genes involved in neuronal plasticity and learning. Early-life experiences produce long-lasting modulation of AP-1 activity, boosting gene networks that strengthen neuronal connections.
Researchers found a significant link between longer screen time and increased ADHD symptoms, as well as developmental abnormalities in brain structure. The study suggests that excessive screen exposure may contribute to delayed brain maturation patterns in children with ADHD.
Researchers found that dogs with stronger ADHD-like traits were slower to learn new information, but improved with repetition and sufficient sleep. The studies also revealed a link between ADHD-like traits and self-control in dogs, suggesting that cognitive training and sleep can mitigate these impairments.
A new study found a significant link between omega-3 intake and ADHD symptoms among Palestinian adolescents. Lower omega-3 consumption was associated with higher ADHD symptom scores, highlighting the importance of balanced nutrition in supporting cognitive health.
SourceDe Gruyter·JournalInternational Journal of Adolescent Medicine and Health·TypeObservational study·DateNov 12, 2025
Researchers have discovered that Batten disease progression varies by sex and age, with male mice showing early auditory problems that improve with age, while female mice experience persistent difficulties. The study provides a new model for tracking brain function over time and testing treatments for this devastating disease.
Researchers have created detailed maps of the mammalian brain's developmental stages, shedding light on how brain cells form and mature. The findings provide valuable insights into the critical periods that may help diagnose and treat neurodevelopmental disorders such as autism and ADHD.
Researchers found that adults behave like children when their working memory is overloaded, showing distributed attention and difficulty in focusing on the task goal. This suggests that children's distractible behavior may be a natural consequence of their developing memory system.
A new tool, WatDAT, measures vision equally precisely in younger toddlers by asking them to point out different shapes at progressively smaller sizes. This test can lead to earlier detection and treatment of vision problems in children under three, such as amblyopia or farsightedness.
A high-resolution growth chart of the mouse brain has been created to study key brain cell types and their changes during development. The atlas reveals a dynamic sequence of brain growth and maturation in response to genetics and external stimuli, with implications for understanding neurodevelopmental disorders.
A significant genetic correlation has been identified between childhood cognitive function and parental longevity, providing molecular evidence for the connection. The study found that shared genetic factors influence both early cognitive abilities and lifespan, with a genetic correlation of 0.35.
A global study by the University of Jyväskylä found that our most emotionally resonant music comes from our teenage years, peaking around age 17. This 'reminiscence bump' helps explain why songs from adolescence remain meaningful even decades later.
A study confirms that people with ADHD can be more creative due to their tendency to let their minds wander. The research found that individuals with ADHD symptoms showed higher scores on creative achievements and were associated with greater mind wandering, particularly deliberate mind wandering.
Adolescents who frequently prefer solitude show measurable differences in brain structure and function, with weaker connections and greater fragility in social circuits. Clinicians can help families recognize risks by spotting early patterns of persistent withdrawal, opening the door to strategies that may protect mental health.
A study analyzing 450,000 ADHD subreddit posts found that people with self-diagnosed ADHD experience more negative self-perception and internalized stigma than those with a clinical diagnosis. Clinically diagnosed individuals are less likely to seek social validation, highlighting the impact of digital age validation on mental health.
A new study by Florida Atlantic University researchers found that heat does not significantly affect the cognitive ability of sea turtle hatchlings. However, higher incubation temperatures negatively impact their physical traits, including shorter incubation durations, lower hatching success, and more frequent scute anomalies. The stud...
A $8.6 million NIH grant has renewed funding for the Rare Disease Clinical Research Network project, focusing on cognition, communication, and neuropsychiatric symptoms in individuals with rare diseases. The initiative aims to develop biomarkers, support pilot projects, and foster skilled investigators.
The study reveals that enzymes KDM1A and KDM5C collaborate to prevent neurons from activating inappropriate genes, ensuring their proper function. This discovery opens new avenues to understand the origin of neurological disorders associated with intellectual disability.
Scientists have discovered key circuit changes that lead to the maturation of reliable brain activity patterns in response to visual experience. The findings suggest that the brain develops a modular organization, with patches of neurons activating together in response to specific features, allowing for efficient learning and adaptation.
Researchers developed a new method to correct for variations in brain imaging measurements, reducing bias and increasing the accuracy of studies on ADHD. The traveling-subject method demonstrated reduced measurement bias while maintaining sampling bias, revealing decreased brain volume in critical regions for cognitive functions.
Researchers observed mother-infant interactions in UK and rural Ugandan communities, finding that cultural context shapes maternal soothing strategies. While UK mothers responded quickly, Ugandan infants recovered faster when soothed with tactile contact like breastfeeding.
A new study published in JAMA Network Open found that toddlers in the US experienced slightly fewer emotional and behavioral problems during the COVID-19 pandemic. The research, which analyzed data from over 3,000 children, suggests that some toddlers may have shown resilience during this time.
Researchers found neglected children had abnormalities in critical brain regions, including right corticospinal tract and superior longitudinal fasciculus, linked to behavioral difficulties. These findings provide objective markers for identifying children affected by neglect.
Most Channel Islands foxes developed larger brains to adapt to survival demands in isolated conditions, defying the assumption that island animals have smaller brains. Brain size appeared to be shaped more by local habitat conditions than isolation or island size alone.
A new study by the Environmental influences on Child Health Outcomes (ECHO) Cohort suggests that higher vitamin D levels during pregnancy may be associated with better cognitive test scores in children. Children of Black mothers, in particular, showed strongest association between vitamin D and cognitive development.
A new study published in PNAS found that prolonged and repeated exposure to GABA anesthetic agents in infants under two months leads to accelerated visual cortical development. This may suggest the use of non-GABA-active anesthetics for newborns, as a large multicenter clinical trial is currently underway.
Professor Yazaki-Sugiyama's research on neural mechanisms of vocal learning during critical periods has significantly advanced our understanding of brain learning mechanisms. She is recognized for her original and outstanding work, which has revealed key findings on neural plasticity.
The brain processes visual information in rapid snapshots roughly eight times per second, resolving competition through rhythmic switching between competing inputs. This 'attentional sampling' mechanism is a fundamental solution to the deep problem of cognition's neural implementation.
A study published in Science Advances found that higher childhood lead levels are significantly associated with a faster rate of forgetting, even at low median blood lead levels. Additionally, older children and those with higher maternal IQs showed better memory retention.
Early life exposure to perfluorohexanoic acid (PFHxA) may increase anxiety-related behaviors and memory deficits in male mice. Researchers found that males exposed to higher doses of PFHxA showed mild developmental changes, including decreased activity levels and increased anxiety-like behaviors.
Mark Ramos developed software to help therapists measure children's skill development in autism therapy, providing a more accurate estimate of mastery. The tool, called MIEBL, employs Bayesian estimates to set performance criteria based on predicted success and observed data.
A new study found that babies are born with the ability to sense physical pain but lack the cognitive understanding of it. The research, led by UCL researchers, used brain imaging data from infants and adults to map the development of pain-processing networks in the brain.
A study of over 1,000 twins found that cognitive tests in infancy can predict adult intelligence and cognition, with environmental influences playing a significant role. Early life environments, including pre-preschool years, matter more than previously thought, suggesting potential interventions to support cognitive aging.
A study of over 700 pregnant women found associations between air pollution exposure and increased volume of brain cavities containing cerebrospinal fluid. Prenatal exposure to nitrogen dioxide, particulate matter, and black carbon were linked to changes in brain structures, including lateral ventricles, cisterna magna, and cerebellar ...
A study of over 2,800 adolescents found that those who got less sleep had reduced connectivity between brain regions critical for decision making and emotional regulation. This can lead to problem behaviors such as aggression and impulsivity.
Researchers found that greenspace exposure is associated with widespread patterns of structural brain development during early adolescence, leading to better academic and mental outcomes. This study highlights the importance of integrating natural environments into urban and educational settings.
The study reveals that white matter microstructure in infants' brains between 3-9 months predicts their emotional development. Infants with certain brain patterns are more likely to exhibit negative emotions or improved self-soothing abilities.
A study of infants aged 16-21 months reveals low rates of overimitation not driven by social affiliation. Other forms of imitation associated with memory and cognition show a correlation, suggesting an earlier emergence of socially motivated behavior.
Researchers have identified a four-amino-acid mini-exon in the PTPδ gene that plays a critical role in brain development and behavior. The study found that deleting this mini-exon led to anxiety-like behavior and reduced movement in mice, highlighting its essential role in maintaining synaptic balance.
A new study from UC Berkeley reveals that the depth of small grooves on the brain's surface is correlated with increased connectivity between regions involved in reasoning. The researchers found that these tertiary sulci, unique to humans, may help explain individual differences in cognitive performance and serve as diagnostic indicato...
A survey of U.K. adults with face blindness reveals the condition's impact on daily life, including difficulty recognizing family members and close friends. The study found that a third of participants struggle to recognize immediate family members, highlighting the condition's significant effects on relationships.
A study by Japanese researchers found that individuals with autism have impaired macrophage function, which may contribute to synaptic pruning deficits. The impaired function is associated with lower expression of the CD209 gene, suggesting a molecular mediator for this process.
A cohort study found maternal hypertension and preeclampsia independently associated with cognitive and language development delays in preterm infants. Recognizing hypertensive disorders of pregnancy is crucial for targeted risk management strategies.
Researchers discovered that infants at 15 months old can use conversational contexts to form initial representations of new words, which helps them later recognize the word when the object is visible. By 12 months, infants may not yet have enough familiarity with familiar words to begin forming a representation of a new word's meaning.
Researchers found that a thicker preoperative macular layer in the right eye was associated with an increased risk of postoperative delirium. The study suggests that retinal imaging may serve as a non-invasive biomarker to identify individuals at risk, particularly after anesthesia and surgery.
A cross-sectional study found that moderately preterm birth was associated with long-term cognitive problems. The study highlights the need for continued follow-up of all preterm children, particularly those born before 34 weeks' gestational age.
Researchers have identified new candidate genes that could be responsible for congenital deafness, a condition affecting around one in 1,000 babies born in the UK. The study suggests that understanding these gene mutations may hold the key to devising effective treatments.
A new study has revealed that Beagle dogs carrying mutations in the Shank3 gene exhibit face processing abnormalities, similar to those observed in human ASD patients. The research provides direct experimental evidence that mutations in Shank3 lead to ASD-like deficits in face processing, contributing to social impairments.
A study published in GeroScience found that weight training improves memory and brain anatomy in older adults with mild cognitive impairment. The results showed that strength training protected against atrophy in key brain areas associated with Alzheimer's disease.
A machine-learning algorithm named catGRANULE 2.0 ROBOT identifies molecular targets for further researches and therapies in neurodegenerative diseases. The algorithm analyzes protein-RNA interaction to predict potential harm and identify early pathological signals.
A research group has uncovered a potential mechanism linking maternal inflammation to delayed neurodevelopment in infants. CD11c-positive microglia, crucial for myelination, play a key role in this process.
Researchers found that ChatGPT makes the same kinds of decision-making mistakes as humans, including biases such as overconfidence and hot-hand fallacy. The study suggests AI needs oversight and ethical guidelines to reduce biases and improve decision-making.
A new study found that children exposed to higher levels of air pollution have weaker connections between key brain regions, potentially disrupting normal brain network development. The associations persist throughout adolescence, suggesting persistent disruptions in brain function.
A groundbreaking study reveals that autistic children exhibit social attention patterns similar to their typically developing peers during play, with a primary focus on toys rather than faces. This challenges the longstanding assumption that reduced eye contact is a definitive marker of autism.
A new digital 'translator' for brain studies enables researchers to map the brain in a standardized way, facilitating discoveries and treatments for various disorders. The open-source software allows for the comparison of brain imaging data with widely used brain atlases, promoting commonalities across findings.
The study found that the 'About Me' Care Card helps clinicians identify patient concerns earlier, creating personalized care conversations. However, some patients with advanced cognitive challenges required assistance, highlighting the need for further development and refinement of the tool.
A new study from the University of Turku screened school-age children for anxiety and found that a Master Your Worries programme reduced symptoms of generalised anxiety, social anxiety, and separation anxiety. The study also showed that lighter digital study materials can reduce anxiety symptoms in children.
A recent study published by the American Academy of Neurology found that increased daytime sleepiness in older women is associated with a double risk of developing dementia. The study tracked 733 female participants over five years and observed significant changes in sleep patterns, including declining nighttime sleep and increasing sl...
A new gamified mobile health app, More Stamina, has been shown to effectively manage MS-related fatigue by helping users track their daily activities and energy expenditure. The study found that the app facilitated conversations between MS patients and their families, improving understanding and support.
A study of 733 older female participants found that those with increasing sleepiness had double the risk of stable sleepers. Poor sleep quality in midlife and delayed dream phase are also linked to a higher risk of dementia. The study adds to recent research on the relationship between sleep patterns and dementia.
Developing multifunctional bioelectronics for organoid interfacing has overcome conventional electronics' limitations. Flexible and stretchable electronics create organoid/electronics hybrids for chronically stable interfaces, enabling electrophysiological recording and multimodal profiling of single cells within 3D tissues.