Articles tagged with Spatial Memory
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Researchers at University College London discovered that Alzheimer's disease disrupts the brain's 'memory replay' process, leading to impaired navigation and memory loss. The study found that even when mice were resting, their brains replayed recent experiences in an altered pattern, which had consequences on memory tasks.
Scientists at Max Planck Florida Institute for Neuroscience have identified a neural code that allows the brain to track distance traveled without visual cues. This ability is essential for navigation and memory formation, and may offer insight into early navigation problems in Alzheimer's disease.
Researchers at USC have identified four distinct layers of specialized cell types in the CA1 region of the mouse hippocampus, a structure vital for memory formation. This discovery changes our understanding of how information is processed in the brain and could explain why certain cells are more vulnerable in diseases like Alzheimer's ...
A new study from McGill University provides insight into how the brain distinguishes objects from background when finding direction. The research found that specific brain areas fired when mice looked at objects, increasing their perception of where they were relative to the object.
Two brain regions have been identified as a neural compass, allowing people to maintain their sense of direction while navigating naturalistic virtual reality cities. These regions are consistent across different city features and task phases, suggesting they track direction relative to the north-south axis.
Researchers found that inhibitory neurons called parvalbumin interneurons reduce activity before a learned reward zone is reached, clearing the way for excitatory neurons to strengthen their bonds and reinforce learning. This finding challenges traditional ideas about neural activity and learning.
Researchers mapped dynamic cellular mechanisms of memory formation, storage and update, revealing new insights into encoding experiences in the brain. Memories are stored through biophysical changes in neuronal ensembles, which can be manipulated to induce recall.
A recent study developed a VR game that combines olfactory stimulation with immersive gameplay to improve cognitive function in older adults. After just 20 minutes of play, participants showed significant improvements in visuospatial rotation and memory tasks.
Researchers found that SIRT2, a previously unknown enzyme, plays a key role in excessive GABA production associated with Alzheimer's disease. This process leads to brain inflammation and memory impairment. By targeting SIRT2, scientists can selectively block its harmful effects on memory without affecting other brain functions.
A new study by UNLV researchers finds that diabetes weakens the anterior cingulate cortex, suppressing reward perception and memory signals, leading to mild cognitive impairment. The connection between high blood sugar levels and Alzheimer's disease may be linked to altered hippocampal theta synchrony.
Researchers at ISTA discovered that neural activity patterns during sleep reflect recently learned spatial memories and transform into those seen later upon awakening. This 'representational drift' phenomenon optimizes memory representations for long-term storage, allowing the brain to free up resources for new memories.
A rat study found that type 2 diabetes can suppress the activity of the anterior cingulate cortex, a region critical for cognition and emotions. This weakening affects reward signals and leads to altered behavior, highlighting a potential link between T2D and psychiatric disorders.
Researchers at Nagoya University found that stimulating CB2 with JWH 133 improved cognitive function and reduced neuroinflammation in AD mouse models. The study suggests that CB2 is a potential therapeutic target for Alzheimer's disease, providing a cost-effective alternative to existing treatments.
Researchers at Monell Chemical Senses Center identified brain neurons that encode memories of sugar and fat, driving feeding behavior and metabolic health. Silencing these neurons impairs an animal's ability to recall sugar-related memories, reducing sugar consumption and preventing weight gain.
A new study by Reichman University reveals a digital treatment protocol improving spatial memory tasks and brain connectivity in aging adults. The innovative mobile app harnesses neuroplasticity to enhance navigational knowledge and potentially mitigate age-related cognitive decline.
Researchers led by UC Irvine have identified two types of neural pathways in the brain's retrosplenial cortex, connected to different parts of the brain. Blocking these pathways affects memory and spatial orientation differently.
Researchers found that cognitive performance worsened for older adults on days they felt lonelier than usual and the following day. The study suggests a vicious cycle between loneliness and cognitive decline over the short term, highlighting the importance of early intervention to prevent chronic loneliness.
Researchers at EPFL have created a unique experimental setup combining non-invasive deep-brain stimulation, virtual reality training, and fMRI imaging to improve spatial memory. The study shows that targeted electric impulses to the hippocampus can temporarily increase brain plasticity, leading to better navigation and recall.
A new study from UT Arlington found that setting reminders can significantly reduce age-related declines in memory, particularly in prospective memory. The study suggests that reminders help counteract cognitive strain by making memory retrieval less reliant on internal processes.
A novel study finds that monitoring cortical microstructural change in the brain using diffusion weighted MRI scans may help identify individuals at risk for cognitive decline and Alzheimer's disease. Tracking these changes over time could provide precious time for disease-modifying treatments.
Nerve cells in the hippocampus region of the bat brain encode information on multiple characteristics of other individuals, including sex and dominance hierarchy. This study sheds light on how the brain operates and generates thinking processes and behavior.
Middle-aged people exhibit reduced exploration when learning a novel maze environment compared to younger individuals. This difference is partially driven by changes in how they learn about the maze, including visiting more objects and pausing for longer periods.
A team of researchers from Rice University and the University of Michigan found that some neurons not only replay recent past experiences but also anticipate future experience during sleep. The discovery provides an unprecedented view of how individual neurons in the hippocampus stabilize and tune spatial representations during periods...
A new study found that mountain chickadees use nearly a hundred genes to recall the locations of cached food items, helping them survive harsh winters. This skill may come at a trade-off, as birds with exceptional spatial memory struggle to form new memories in changing environments.
Researchers found that ketogenic diets reduced plasma levels of total Tau in females, mitigated elevations in plasma lipids, and improved circulating lipids. However, neither continuous nor intermittent ketogenic diets improved measures of cognitive or motor behavior in the TgF344-AD rat model.
A two-week yoga nidra intervention increased sleep efficiency and percentage of delta-waves in deep sleep, leading to improved cognitive abilities such as decision-making and abstraction. Cognitive tests revealed faster responses with no loss in accuracy.
A new study by University of Arizona psychologists investigated the possible scenarios leading to waning memory in older people. The researchers found that the hippocampus contributes to the difficulty in learning new environments and locations in some older adults.
A study involving wolves and dogs found that both species can remember where people hid food if they observed the hiding process. However, wolves outperformed dogs in finding caches, suggesting differences in traits like persistency and food-related motivation.
Researchers found that bat's place neurons encoded information about the presence and identity of other bats in their social space. The study reveals how the same hippocampus structure that navigates through space also helps bats navigate complex social behaviors.
Researchers found that Period 1 gene becomes more active in memory-forming region of brain in daylight hours after learning, playing crucial role in consolidating memories. Mice exhibit improved daytime memory performance compared to nighttime.
Researchers discovered that adult and aged mice demonstrated improved performance in behavioral tasks after environmental enrichment, with MSK1 playing a vital role. The study highlights the importance of MSK1 in converting positive experiences into cognitive benefits across the lifespan.
A new study published in Aging (Albany NY) suggests that prior training can rescue cognitive decline in aging by improving task performance and strengthening memory processes. The research, conducted on rats, found that prior training enhanced short-term and intermediate memory, while also enabling encoding-boosted long-term memory.
Researchers from Mount Sinai Health System presented new findings on the impact of customized lighting on inpatient sleep, a machine-learned combination of ventilatory, hypoxic, and arousal burdens, and the effects of obstructive sleep apnea and insomnia on cognitive impairment. The studies aim to improve sleep timing and duration, dia...
Researchers at the Institute for Basic Science have identified specific neurons in the hippocampus that allow us to recognize individual social counterparts and update their value through interactions. The dorsal CA1 region plays a crucial role in this process, enabling long-term memories of individuals to be formed.
A study by Florida Atlantic University and CINVESTAV found that long-term running maintains the connectivity of adult-born hippocampal neurons, which contribute to memory function during aging. Exercise may prevent or delay age-related memory decline by increasing the survival and modifying the network of these neurons.
Researchers have identified α5-GABAARs on interneurons as key receptors regulating memory formation in the hippocampus. Selectively knocking out these receptors from interneurons impaired spatial memory, while leaving pyramidal neurons unaffected.
A Dartmouth study found that COVID-19 can cause 'prosopagnosia,' or face blindness, and impairments in navigational abilities. Researchers worked with a patient who experienced difficulty recognizing faces and navigating, leading to dissociation between face recognition and cognitive map representation.
Researchers found that suppressing AMPKα1 but not AMPKα2 isoforms improved aging-related impairments in mice. The study revealed novel insights into the roles of AMPK signaling pathway in cognitive aging.
A study found that people can recall the location of over 100 objects on a grid with high accuracy, even after removing all images. Additionally, participants localized 60-80% of old items to within +/-10% of their correct time.
Researchers found that orienteering can improve spatial navigation and memory in healthy adults, suggesting it could be a useful intervention to prevent cognitive decline. The sport's unique combination of physical exercise and navigational skills may stimulate parts of the brain that are no longer needed due to modern conveniences.
A new study reveals that astroglial cells, a type of glial cell, are essential for the integration of sensory information from a location, enabling spatial learning and memory. This mechanism involves the release of D-serine, which strengthens dendritic spikes, facilitating the recognition and storage of familiar places.
Researchers have discovered a human-approved medication that can bring back 'lost' memories in mice, suggesting a potential new approach to treating age-induced memory problems or early-stage Alzheimer's disease. The study used optogenetic approaches and the asthma drug roflumilast to revive memories stored in the hippocampus.
Neuroscientists have uncovered a brain circuit that enables mice to rapidly escape to shelter when faced with a threat. The retrosplenial cortex and superior colliculus form a circuit that encodes the direction to a shelter, allowing mice to accurately orient and escape.
A new study from Dartmouth College found that specific intensities of exercise over a long period are associated with different aspects of memory and mental health. Participants who exercised at moderate intensities performed better on episodic memory tasks, while those who exercised at high intensities did better on spatial memory tasks.
Scientists at Harvard Medical School have made a breakthrough in understanding how the brain forms spatial maps. A new study reveals that the gene Fos plays a crucial role in this process, helping the brain use specialized navigation cells to form and maintain stable representations of the environment. The findings provide new insights...
Researchers propose a novel paradigm using nanoscale nonlinear fluid dynamics to support recurrent neural networks in neuromorphic computing. The liquid film functions as an optical memory, enabling 'reservoir computing' capable of performing digital and analog tasks.
Research suggests that individuals with PTSD exhibit decreased activity in the hippocampus, leading to impaired threat reactivity and memory formation. This study reveals a significant interaction between hippocampal activity and physiological arousal in predicting PTSD symptoms.
Researchers identified a key brain circuit in the anterior thalamus that helps us hold information in mind. In a study of mice, enhancing this circuit's activity improved their ability to navigate a maze and reversed memory loss with artificial stimulation.
A study found that intact astrocyte networks are essential for neural homeostasis, synaptic plasticity, and spatial cognitive abilities in adult mice. Disrupting these networks impairs spatial learning and memory due to altered neuronal excitability and compromised synaptic transmission.
Research finds prepubescent female rodents outperform males in hippocampal long-term potentiation and spatial learning, reversing after puberty. The study proposes optimal teaching strategies should adapt to brain differences between sexes during this critical life stage.
A ketogenic diet has been shown to improve spatial memory and visual memory, lower brain inflammation indices, and cause less neuronal death in individuals with traumatic brain injuries. The diet may also slow down the rate of cellular aging, offering hope for those suffering from this condition.
A UCI-led research team has identified novel functional roles of new circuit connections between the CA1 region and dorsal CA3 regions of the hippocampus. Genetic inactivation of this projection impairs object-related spatial learning and memory, but does not modulate anxiety-related behaviors.
Researchers have found that stimulating the anterior thalamus can increase memory-related brain activity and restore memory function in rats with MTT lesions. The study suggests that therapies targeting this region could help recover memory in patients with brain injury, challenging previous notions of memory recovery.
A systematic review found spatial neglect to be prevalent among 29% of unilateral stroke survivors, with higher rates in right brain strokes and ecological assessments. This condition impairs cognitive and motor functions, slowing rehabilitation progress and increasing risk for injury.
A new study by the University of Plymouth and Essex found that many adults struggle to imagine their own visual perception as a flat image, resisting the idea of 'corrected' vision. When shown two lines with different lengths, participants often judged them as equal in length, despite being able to see one as longer when viewed on camera.
Researchers found mammalian-like hippocampal activity in food-caching songbirds like the tufted titmouse, which processes spatial memory using mechanisms similar to those in mammals. This challenges long-held assumptions about the neural basis of spatial memory in non-mammals.
Researchers studied rats in mazes to observe brain cell activation during correct and incorrect memory recall. They found similar patterns of cell activation, but with different timing and energy levels, suggesting a link between memory disorders like Alzheimer's and faulty retrieval.
Researchers at the University of Tsukuba found that both endurance and high-intensity intermittent training improved exercise capacity and brain function in rats. HIIT resulted in increased cellular aerobic capacity and better memory for spatial learning trials.
Researchers at Dartmouth College have identified three brain areas, known as place-memory areas, which form a link between perception and memory systems. These areas are responsible for transforming visual information into spatial knowledge of familiar places.
A study from MIT neuroscientists has identified a hippocampal circuit that stores information about the timing of events, allowing mice to remember when to turn left or right in a maze. Disrupting this circuit impaired their ability to remember direction, but not location.