A new study by Kaiser Permanente found that mailing human papillomavirus (HPV) self-sampling kits to patients increases cervical cancer screening completion rates. The study also shows that this approach is cost-effective, especially for health systems with a wide range of patient populations.
A study by Harvard University found that EurekAlert! press releases were 4 times more likely to receive U.S. media coverage than journal articles without press releases. The researchers analyzed 1,155 archaeology papers and found that over 90% of those published in top journals were covered by at least one major U.S. news outlet.
A higher cumulative cardiovascular health score in young adulthood is associated with reduced risk of cardiovascular disease and kidney events in midlife. The study emphasizes the importance of early life prevention efforts.
Scientists at PSI have developed a dynamic database for vanadium, crucial for storing surplus wind and solar power. The database provides reliable data on raw materials, including ore deposits, mining volumes, and prices, to facilitate long-term investment and policy decisions.
Scientists have developed an imaging technique to visualize and quantify alpha-synuclein oligomers in human brain tissue, a major advance in Parkinson's research. The study found that oligomers exist in both healthy and Parkinson's brains, but are larger, brighter, and more numerous in disease samples.
A 430-million-year-old fossil found in Wisconsin reveals that ancient leeches feasted on smaller marine creatures, challenging the assumption that they are bloodsuckers. The absence of a forward sucker in the fossil suggests a different early lifestyle for the group known as Hirudinida.
Researchers developed Giotto Suite, a modular software platform that streamlines the study of tissue biology and disease mechanisms. The tool supports various analyses, including data integration across different types of measurements and resolutions.
New research reveals fungi's deep timeline, dating back 1.4-0.9 billion years, which influenced ancient terrestrial ecosystems and shaped the evolution of life on land. The study uses rare genetic 'gene-swap' clues to overcome the fungal fossil record gap.
Researchers reveal protons and superoxide ions mediate long-distance charge transport between cytochrome c and respiratory complex III. This discovery improves understanding of cellular respiration regulation and could inspire new protonic devices.
A study by Osaka Metropolitan University reveals that community involvement is a powerful driver of acceptance among people with poor health. The research found that increasing the density of stops in residential areas can make demand-responsive transport more accessible to those with limited mobility. The study's findings suggest that...
The Swiss Alps have experienced its fourth greatest shrinkage of glacier ice since 2003, with over 1,000 small glaciers disappearing since 2015. The rapid melting was driven by low snowfall and record-breaking heatwaves in June 2025.
Researchers engineered CAR T cells to produce a fusion of IL-12 cytokine and a PD-L1 blocker, boosting immune activity against solid tumors. The modified cells were found to be highly effective in shrinking ovarian and prostate tumors while minimizing side effects.
Scientists have found new complex organic molecules spewing from Saturn's moon Enceladus, confirming that complex chemical reactions are taking place within its underground ocean. The discovery strengthens the case for a dedicated European Space Agency (ESA) mission to orbit and land on Enceladus.
Recent studies using portable nanopore sequencing technologies document and sequence Amazonian wildlife, increasing representation of Peruvian species in global genetic libraries. This initiative empowers conservationists to generate their own data, making informed decisions to combat species extinction.
A study published in Mayo Clinic Proceedings found that shift workers have a 15% higher risk of developing kidney stones, especially younger workers and those with low levels of manual labor. Lifestyle factors such as BMI, fluid intake, and smoking habits significantly contribute to the occurrence of kidney stones.
A polygenic risk score (PRS) can predict future breast cancer incidents in women diagnosed with ductal carcinoma in situ (DCIS) or lobular carcinoma in situ (LCIS). PRS scores were associated with an increased risk of ipsilateral breast cancer, particularly in patients with a family history of breast cancer.
Researchers developed a sensor system to measure piano key movements at 1,000 fps and found listeners could distinguish intended timbres regardless of training experience. Key movement features produce timbre differences, suggesting potential applications in rehabilitation, skill transfer, and human interface design.
Researchers at King's College London have developed a genetic test that can predict which women with abnormal breast cells are most likely to develop invasive breast cancer. The test uses a genetic risk score to estimate a person's inherited likelihood of developing the disease, allowing for more personalized treatment options.
Researchers at Columbia University have successfully used an AI-guided sperm recovery method to help a man with azoospermia become pregnant. The STAR method combines advanced imaging technology and microfluidics to identify and isolate rare sperm cells, overcoming long-standing barriers in treating men with infertility. Larger clinical...
Nuclear chemists at the University of Cologne provide experimental proof of technetium-98's electron capture decay into molybdenum-98. The finding confirms a decades-old theoretical assumption and expands understanding of nuclear decay processes.
A University of Minnesota Medical School research team, led by Ziad Nahas, has been awarded a $4.4 million grant to explore how large-scale brain networks regulate mood in bipolar disorder. The team will test a novel type of brain stimulation called Personalized and Adaptive Cortico Electrostimulation (PACE) to relieve symptoms and ide...
Jülich researchers create model to detect ballistic electrons in two-dimensional materials, enabling the identification of lossless current flow. This breakthrough could lead to the development of robust qubits and energy-efficient circuits.
A team of scientists has developed a breakthrough floating droplet electricity generator that directly incorporates natural water into its structure, reducing material weight by about 80% and cost by about 50%. The device produces high peak output voltages comparable to conventional systems.
Researchers developed a scalable method to produce human kidney organoids, combining them with pig kidneys outside the body for transplantation. The transplanted organs functioned normally and showed no signs of damage or toxicity.
A new study from Memorial Sloan Kettering Cancer Center identifies unique genetic signatures in cancer patients of non-European ancestry and finds adding immunotherapy can boost effectiveness for hard-to-treat follicular lymphomas. Additionally, researchers discover a web-based system to report head-and-neck cancer concerns, leading to...
The proposed approach leverages AI to create intelligent, personalized learning platforms that facilitate the synergistic development of IP knowledge and ideological-political values. This integration improves teaching quality, cultivates students' legal awareness, innovation capacity, social responsibility, and practical skills.
The American Heart Association is launching a three-year quality improvement initiative to address gaps in pulmonary embolism (PE) care. The initiative aims to advance best practices for PE diagnosis, treatment, and follow-up care by convening diverse care teams and sharing data, insights, and experiences.
Research shows that families exposed to war and political violence exhibit aggressive behavior, influencing children's lives. The trauma alters family interactions and dynamics, creating harsh interactions that transmit injury across the household system.
Researchers explore manganese's impact on cancer immunotherapy, highlighting its potential to boost anti-tumor effects and induce immunogenic cell death. The review aims to synthesize findings on the cGAS-STING pathway and Mn's overall role in immune checkpoint therapy.
The Subsidiary Body on Article 8(j) and Other Provisions of the Convention Related to Indigenous Peoples and Local Communities has been established to elevate the role and contributions of these groups. The body aims to promote greater environmental democracy, with women and youth expertise being reflected in its work.
Engineers develop a self-forming protective layer to prevent dendrite growth and parasitic reactions, enabling unprecedented performance and resilience. The bi-directional regulation system maintains stability across wide temperatures, paving the way for practical grid-scale applications.
A recent study analyzing millions of social media posts found that news shared on platforms with conservative user bases is lower in quality, yet gets more likes and shares. Meanwhile, a user's posts with lower-quality news links get more engagement than their higher-quality news posts across both liberal- and right-leaning platforms.
A literature review of cheese fermentation and ripening identified five underused, evidence-based measures to improve efficiency and sustainability in cheese production. By exploiting whey and encapsulating lactic acid bacteria, dairies can reduce waste and optimize production processes.
Patients with access to GeneSight results for depression treatment showed faster initial remission and response. The post-hoc analysis also found persistent benefit over six months, without evidence of changing over time.
Researchers discuss major advances in contraception but highlight substantial gaps, particularly in underserved populations. The study emphasizes the need for improved contraception choices to enhance women's health, economic status and well-being.
A study led by Dr. Yasuyuki Fujii found that flavanols activate the brain's sensory nerves, inducing physiological responses similar to those induced by exercise, improving attention, arousal, and memory. Flavanol intake also boosted neurotransmitter activity, strengthened the noradrenergic system, and enhanced stress response regulation.
A new study from North Carolina State University finds that bamboo tissue paper produced in China has a significant carbon footprint, comparable to or even higher than traditional tissue made from wood. The researchers found that the technology used to create hygiene tissue paper is more important than the type of fiber it's made from.
A new imaging study has visualized how brain network development is altered in a rare childhood disorder, KCNQ2-related developmental and epileptic encephalopathy. The study found that changes in brain function occurred before behavioral symptoms appeared, suggesting early interventions may be effective.
The editorial highlights how biological sex and gender inequities contribute to suboptimal sepsis treatment, potentially compromising outcomes for women. Hormonal fluctuations, body composition, and renal clearance all influence drug processing, yet these variables are rarely considered in dosing algorithms.
Researchers have developed a solid-acid NiCo2O4 electrocatalyst with balanced Brønsted and Lewis acid sites for efficient electrooxidation of biomass-derived saturated alcohols. The work offers a new strategy for designing high-performance, non-noble metal catalysts for biomass valorization.
Researchers have made significant progress in pulsed electrolysis, a method that uses excess nitrogen from air and water to produce valuable compounds like ammonia and urea. This energy-efficient process has the potential to reduce greenhouse gas emissions and promote sustainable agriculture.
A University of Delaware student's unexpected rise as a researcher led to critical new insights into human papillomavirus (HPV) and its role in cancer. The study found that specific mutations in HPV proteins may increase cancer risk, paving the way for improved approaches to diagnosing and treating HPV-related cancers.
Researchers found that interferon-gamma signaling in myeloid cells corresponds with resistance to immunotherapy in advanced renal cell carcinoma. This study could help identify biomarkers for predicting response to immunotherapy and inform the development of new therapies.
Researchers discovered that docosahexaenoic acid (DHA) plays a crucial role in heart regeneration by triggering specific genes involved in the process. Injection of DHA improves cardiac function in adult mice after myocardial infarction, while also facilitating cardiomyocyte proliferation and inhibiting fibrosis and inflammation.
Researchers at DGIST discovered a new regulatory factor called 'chlorella RNA' that regulates the aging of plant leaves. The study found that chlorella RNA affects the transcriptional regulation activity of chloroplasts, leading to a decline in photosynthetic function and degradation of chloroplasts.
A new security framework based on blockchain technology and distributed reinforcement learning ensures secure data storage and transmission while adapting to evolving threats. The framework demonstrated improved memory consumption and transaction latency compared to existing approaches.
Researchers have uncovered a novel mechanism linking lactate metabolism to muscle Growth differentiation factor 15 (GDF15) release during mitochondrial stress, providing a potential therapeutic target for mitochondrial myopathy. Elevated lactate production and histone lactylation activate GDF15 gene expression.
Researchers reviewed novel photonics breakthroughs of 2024, focusing on coupling free electrons with nonlinear optical states in integrated photonic microresonators. This enables ultrafast electron-beam modulation and novel research opportunities for electron imaging and spectroscopy.
Research links low body weight in young Japanese women to reduced gut microbial diversity, with an increased presence of inflammatory species. The study suggests that improving eating habits could lead to improvements in gut microbiota and body weight.
A multidisciplinary team of scientists at Scripps Research has been awarded $6.9 million to identify more effective vaccines for treating HIV. By combining cutting-edge techniques and leveraging novel mouse models, the researchers aim to create a roadmap for building vaccines that provide lasting protection against HIV.
Research by Dr. Dorothy Vesper and her team found that abandoned coal mines can transport CO2 from bedrock to the atmosphere through unremediated discharge. The mine waters, loaded with sulfuric acid, break down carbonate rocks releasing ancient CO2 that then converts to CO2 or other forms of carbon in the water.
A practical, evidence-based checklist developed by scientists at the University of Surrey is helping everyone plan their next greening project with confidence. The study found that mixed gardens, such as small front gardens with a tree, shrubs, and green walls, give the greatest economic benefits for their size.
Researchers have discovered a key role for the Frazzled protein in fruit fly neural circuits, revealing how it helps neurons form reliable connections. The study showed that when Frazzled is missing or mutated, neurons fail to form proper electrical connections, leading to communication breakdowns.
Researchers at Yonsei University have developed a groundbreaking fluoride-based solid electrolyte that enables all-solid-state batteries to operate beyond 5 volts safely. The innovation allows spinel cathodes to operate efficiently and retain over 75% capacity after 500 cycles.
A research team discovered that leucine prevents the degradation of specific mitochondrial proteins, enabling efficient energy production. This mechanism allows cells to adapt to increased energy demands during periods of nutrient abundance.
A cross-sectional study found associations between structural racism and inequities in neighborhood cardiovascular health, highlighting the need for targeted prevention efforts. The study's findings underscore the critical role of addressing systemic inequalities in promoting health equity.
The SCALE taxonomy introduces a novel framework of educational objectives that align human learning with the emerging needs of the AI age. It encompasses scientific literacy, computational thinking, AI literacy, metacognition, and engineering and design thinking.
The current NHS rollout of Mounjaro is expected to reach only around 200,000 patients in the first three years. Meanwhile, over one and a half million people are accessing private treatment for obesity. Researchers warn that strict eligibility criteria may exclude vulnerable patients from receiving treatment on the NHS.
Researchers have successfully developed an asymmetric synthesis method for quebracho indole alkaloids using a nickel-catalyzed [2+2] cyclobutanization reaction with flexible antenna ligands. The method achieved high yields and precise control in 7-10 steps, including the first-ever asymmetric syntheses of three naturally occurring comp...
A team from the University of Barcelona identified genetic mechanisms involved in the degradation of the vestibular system caused by ototoxic compounds. The results could help improve diagnosis and treatment of chronic vestibular ototoxicity and related pathologies.