Researchers at King's College London have been awarded £191,000 to enhance the prediction of aortic coarctation by adapting their established biomarker from MRI to ultrasound. The goal is to improve the accuracy of CoA diagnosis before birth using routine 2D scans.
A study by European Society of Cardiology found that AI-based ECG interpretation outperformed standard pathways in detecting occlusive myocardial infarction (MI) without ST elevation. The AI tool correctly identified obstructive MI in 84% of cases, with high sensitivity and specificity rates.
Researchers identified SHP protein as a key regulator protecting cartilage from degeneration in osteoarthritis. Restoring SHP levels slowed cartilage damage and improved joint function in mice.
Michael Franklin, former Liew Family Chair of Computer Science, has been appointed Deputy Dean for Computational and Mathematical Sciences. He will lead strategic planning to advance these disciplines and foster collaborations across campus.
A research team led by Prof. Wang Zuankai has discovered the mechanism behind mechanoelectrical perception in sea urchin spines, which allows them to detect water flow instantly. The team has developed a bionic metamaterial sensor using gradient porous structure and 3D printing, holding promise for sensing technology breakthroughs.
A computational method called scSurv links individual cells to patient outcomes using bulk RNA sequencing data, identifying cell populations associated with survival across several cancers. The model estimates the contributions of over 10,000 individual cells to disease risk and prognosis, providing a foundation for precision medicine.
Researchers found the brain's internal compass, tracking direction and spatial information, remains structurally intact despite changes in memory structures, suggesting it acts as an anchor for memory. This stability could help clarify why spatial abilities deteriorate in Alzheimer's disease.
Scientists have created the first lab-grown oesophagus that safely replaces a full section of the organ and restores normal function in growing animals without immunosuppression. The technology has shown promising results, providing a blueprint for human treatment and offering hope for families affected by life-threatening oesophageal ...
Researchers analyzed genetic data from over 2.2 million individuals to understand how genes shape vulnerability to alcohol, tobacco, cannabis, and opioid use disorders. They found that genetic risk operates along two main pathways: one related to brain wiring and the other specific to each substance.
Researchers have developed programmable 2D material–organic molecule hybrids with high efficiency and nanoscale spatial precision using DNA origami triangles. This approach enables the creation of arrays of solid-state single-photon-emitter ensembles with excellent spectral and intensity stability, opening a route toward miniaturized h...
A comprehensive study reveals substantial declines in many South African raptor and large terrestrial bird species over the past 16 years. Researchers detected sharp declines in threatened and iconic raptors, including the Endangered Secretarybird, highlighting the vulnerability of species dependent on multiple regions.
A computer simulation improved understanding of refugees among Swedish teenagers who experienced simulated migration journeys. The study found that students exhibited increased social understanding and empathetic attitudes towards immigrants.
A deep neural network model has achieved global precision in predicting nuclear charge density distributions, surpassing traditional methods by over 50% accuracy. The model's innovative approach combines physical mechanisms with artificial intelligence to provide a unified description of charge density and charge radius.
A study found that sleep apps can have negative effects on people with insomnia symptoms, causing more worries and stress. While the apps helped some users, younger adults reported stronger effects, while older individuals responded less.
Researchers at the University of South Florida used fluorescent imaging to map out Toxoplasma gondii's cell cycle, revealing its unique growth stages and potential weak points. The study aims to develop safer and more effective treatments for toxoplasmosis, a parasite that infects nearly one-third of the global population.
LazySlide enables systematic whole-slide image analysis using AI models and links visual patterns to text concepts. The study demonstrates its potential in analyzing tissue samples, identifying biological pathways, and reducing the barrier for applying advanced image analysis methods.
A new study calls for dedicated research to guide the sustainable and commercially viable development of Via Ferrata tourism. The sport, which combines elements of hiking, mountaineering, and rock climbing, has experienced rapid growth globally, but lacks a consolidated evidence base.
The study investigated the link between heart attack-induced inflammation and cognitive decline, as well as the potential of PET-based metabolic tumor volume to predict CAR T-cell therapy outcomes. Additionally, researchers combined advanced imaging with genetic profiling to explore hidden metabolic patterns in recurrent brain cancer.
A biomimetic smart insole system integrates high-resolution sensing, autonomous energy supply, and AI-assisted gait diagnosis to monitor lower limb function and disease progression. The system achieves ultra-low detection limits and maintains mechanical stability, addressing existing bottlenecks in wearable gait monitoring.
Climate warming significantly increases plant growth in permafrost regions by altering growing seasons and root penetration, but its impact depends on nitrogen supply. A new study reveals that moss-associated biological nitrogen fixation is a critical factor in sustaining plant growth under warming conditions.
Dr. Chun Li has been awarded the SNMMI Mars Shot Research Fund Award to investigate the PET radiotracer 64Cu-DbCD11b for detecting vulnerable atherosclerotic plaques. The study aims to assess the non-invasive assessment of vulnerable plaques and aid in patient risk identification and treatment.
Researchers Ansel Hillmer and Eric Webb have received the $100,000 Drs. Jane & Abass Alavi Mars Shot Research Award to advance imaging research in infection and inflammation for Alzheimer's disease. They aim to develop a PET radiotracer targeting CSF1R to diagnose and monitor brain inflammation.
Researchers discovered a metabolite called pTOS in pythons that increases appetite suppression in obese mice, leading to significant weight loss. The study sheds light on the power of studying extremes in the animal kingdom and may lead to new weight-loss treatments.
A study of over 340,000 British adults found that low to moderate wine consumption was associated with a significantly lower risk of death compared to spirits, beer, and cider. Moderate wine drinkers had a 21% lower risk of dying from cardiovascular disease, while even low intake of spirits, beer, or cider was linked to a 9% higher risk.
A decrease in colorectal cancer incidence was observed among individuals with negative screening colonoscopy results, particularly men, suggesting risk-based follow-up strategies. Nonadherence to scheduled colonoscopies increased the risk of CRC, highlighting the need for targeted interventions to improve early detection.
A team of ETH Zurich researchers developed a process to convert sawdust into a recyclable and environmentally friendly composite using struvite. The material exhibits excellent fire resistance due to the mineral's non-combustible properties and cooling effect, making it suitable for internal fittings.
The 'leaky pipeline' metaphor oversimplifies the systemic barriers faced by women and marginalized scholars in archaeology. New research highlights multiple forms of inequity that diminish productivity, limit collaborations, and reduce future generations of archaeologists.
Researchers tracked mouse groups during cold exposure and found that individual brain activity influences collective behavior, leading to self-correction when one member is compromised. The study highlights the importance of considering the whole group in understanding brain function.
The Hefei Botanical Garden is a key institution for biodiversity research in East China, with over 5000 plant species preserved, including rare and endangered species. The garden promotes sustainable resource utilization, ecological education, and rural revitalization through its 'Botanical Garden + Agriculture' model.
A study found that the aquatic plant Salvinia auriculata can act as a sink for antibiotics in the Piracicaba River, reducing bioaccumulation and genotoxicity. The plant was able to remove high concentrations of enrofloxacin and chloramphenicol from the water, but its effectiveness varied depending on the compound.
Research reveals postpartum GBS strains with mutations that allow them to survive in the birth canal and resist treatment. Identifying these mutations is crucial for understanding how GBS is evading antibiotic treatment and finding new drug targets.
Streptococcus mitis bacteriocins selectively target S. pneumoniae, highlighting potential as antimicrobial strategies. DNA exchange between species facilitates bacterial adaptation and shapes evolution in human respiratory environments.
Scientists at Osaka Metropolitan University developed high-performance lead-free piezoelectric thin films directly on standard silicon wafers. The films achieved the highest piezoelectric response ever reported for bismuth ferrite, enabling a fivefold improvement in energy conversion efficiency.
Researchers discovered an appetite-suppressing compound in python blood that promotes satiety without stomach problems. The compound, para-tyramine-O-sulfate, has potential for new weight loss treatments.
Researchers develop method using biomarkers to calculate individual biological age, finding significant differences in age-related changes between men and women. The study also identifies clinically relevant biomarkers linked to biological age, opening up new opportunities for preventive medicine.
The Berlin Battery Lab brings together top-level research institutions to develop and test resource-efficient battery technologies, focusing on sodium-based systems. The lab aims to accelerate the transfer from research to application, supporting the development of locally produced, sustainable battery technologies.
A minimally invasive liquid biopsy test has been shown to diagnose Burkitt lymphoma rapidly and accurately in sub-Saharan Africa, where delays in traditional testing often prove fatal. The test achieved an overall accuracy of 98% and reduced the time needed to reach a diagnosis by 40 days on average.
Researchers at Stockholm University propose a novel approach to detecting gravitational waves by tracking how they reshape the light emitted by atoms. This method could help distinguish the signal from noise and encode the wave's direction and polarization.
New research reveals how psychological stress worsens atopic dermatitis, also known as eczema, by activating a specific neural pathway. This pathway links the brain to immune responses in the skin, leading to increased inflammation and worsening symptoms.
The MountAInWater project uses a unique combination of field work, modeling, and AI to assess climate change impacts on mountain water supplies and identify potential tipping points. The global reanalysis will provide crucial resources for managing future water security challenges.
Researchers tested robots with factual and fictional dialogue on SEL lessons, finding that the factual robots encouraged deeper engagement and improved mastery. The study challenges conventional wisdom on robot design for education, suggesting that robots can be powerful supplements to human teaching.
Researchers identify the ventromedial prefrontal cortex (vmPFC) as the brain region associated with moral inconsistency. Studies show that individuals with less vmPFC activity are more likely to be morally inconsistent, indicating a failure to integrate moral knowledge into daily behavior.
A new study using radiocarbon methods reveals that sea turtle shell plates are biological time capsules that record signs of major environmental disturbances in the ocean. By analyzing these layers, scientists can determine where turtles have been foraging and how marine environmental stress events affected them.
Researchers Haj-Mirzaian and Heidari aim to develop non-invasive imaging biomarker <sup> 18 </sup> F-NaF PET/CT for early calciphylaxis diagnosis in dialysis-dependent patients. This could lead to timely interventions, reduced mortality, and improved patient outcomes.
A recent study found that type-1 narcolepsy is caused by the body's own immune system, specifically an increased number of CD4 T-cells in the hypocretin/orexin region. This discovery could steer research towards finding a potential cure and blocking the immune activity before it starts.
Frontiers, a leading open access publisher, has joined the LIBER sponsorship program as a Gold Sponsor to support European research libraries. This collaboration aims to promote open science, address the challenges of the publishing landscape, and better support researchers and research libraries.
Research published by the American Psychological Association found that storytelling in dating profiles creates empathy and connection, attracting more interest from potential dates. By humanizing profiles, storytelling counters the objectifying nature of online dating platforms.
Researchers analyzed data from 2,500 US women and found that those consuming fewer ultra-processed foods had higher fertility rates. The Mediterranean diet showed a positive association with fertility, but this benefit disappeared once obesity was factored in.
The Center for Scalable and Intelligent Automation in Poultry Processing will hold its first field day on April 9 to share research on developing new robotic technologies. Researchers will demonstrate tools for deboning, detecting foreign materials and pathogens, as well as using virtual reality to operate equipment remotely.
Researchers at MIT have developed a new technique using generative artificial intelligence models to overcome the precision bottleneck in wireless vision systems. The method produces more accurate shape reconstructions, which could improve robots' ability to grasp and manipulate objects blocked from view.
A large study finds that Medicare Part D beneficiaries saw a substantial decrease in out-of-pocket insulin costs following the implementation of a $35 cap. The percentage of patients paying $35 or less increased from 48% to 75%, and mean costs dropped from $50.87 to $21.98 between 2019 and 2023.
Researchers developed a tool that combines wild bird abundance and cattle density data to predict where and when the risk of infection is highest in Denmark. The study warns that Danish cattle are particularly vulnerable due to their location along migratory bird routes, with the risk of infection highest from December to March.
Two-thirds of private wells in the São Paulo Metropolitan Area are not formally registered, posing a risk to groundwater consumption. The area is contaminated by toxic industrial waste, including chlorinated solvents used for cleaning machines.
The event aims to connect grain farmers with buyers from the region to discuss market opportunities for organic grain crops. Presenters will also showcase ongoing organic research in Arkansas.
Lawrence Toll has been named a senior member of the National Academy of Inventors for his pioneering work on pain pathways, reward systems, and potential treatments. His research focuses on identifying new drug targets and therapeutic strategies to combat chronic pain and addiction.
Researchers have achieved first-ever in-situ polarization control in high-field infrared spectroscopy, overcoming a decades-old technical bottleneck. The newly developed collimated magneto-infrared spectroscopy system enables continuous modulation of polarization states under high magnetic fields and cryogenic temperatures.
Researchers create a new method that combines quantum and classical computing to solve optimization problems more efficiently, potentially achieving higher accuracy and quantum advantage. The QIAPO project aims to improve the performance of industrial processes and distribution by finding more efficient solutions.
The Robert A. Winn Excellence in Clinical Trials Award Program is expanding its career development award to include neuropsychiatry researcher-physicians. This expansion aims to improve clinical trial enrollment and represent diverse patient populations affected by complex disorders.
A recent study published in Science found that humans and animals have overlapping preferences for certain qualities of an animal's call, with agreement strongest for lower-frequency sounds. The study used a gamified citizen science experiment involving over 4,000 human participants from around the world.
Researchers developed a plant-level carbon accounting framework combining satellite imagery with textual industrial data to estimate emissions from 720 pulp and papermaking plants. The approach identifies high-emission plants and functional zones associated with emissions, offering a basis for industrial decarbonization. rooftop solar ...