A new study found that insomnia disrupts the body's ability to learn and remember that a threat is gone, leading to a reduced capacity to extinguish physiological threat responses. This is associated with a reduced safety memory and increased arousal during recall.
A recent study revealed that corn cultivation played a crucial role in the subsistence and development of large villages in the Brazilian savanna. The research, which analyzed minute chemical variations in human bones and teeth, provided a record of diet throughout life. Corn consumption was comparable to that of Mayan and Andean popul...
A new international study found that population levels in Japan after the Kikai-Akahoya eruption were more complex than previously believed. The research team discovered that while populations declined in some areas, they actually increased in others, with survivors adapting to new social relations and economies.
A new algorithm enables off-the-shelf computers to run quantum simulations previously only possible using the world's most powerful supercomputers. This breakthrough could make it cheaper and easier to run experiments vital for understanding the limitations of current quantum computers.
A 20-year study reveals that 287 million people globally were exposed to both heatwaves and wildfires on the same days, with over half of the world's population affected. The study warns that cardiovascular and respiratory illnesses will continue to increase as climate warming leads to more combined heatwaves and wildfires.
Researchers have developed TMD-based systems with strong and broadband absorption, achieving efficient impedance matching and energy attenuation. Multicomponent systems can push performance further, offering multifunctional architectures with thermal and mechanical functions.
Recent advances in wearable electronics are transforming these devices into promising platforms for continuous, personalized precision diagnosis. The integration of multiple sensing modalities and artificial intelligence enables early disease detection, longitudinal health monitoring, and personalized medical management.
A study by Semmelweis University researchers found that adolescents with functional abdominal pain disorders experience multisite pain and report stress, anxiety, and social struggles. These symptoms can persist for years and impact daily life, highlighting the need for further investigation and support.
A new analysis of US national health data found that inflammation increases across the stages of cardiovascular-kidney-metabolic syndrome, with the largest increase at the earliest stage. Average hs-CRP nearly doubled between stage 0 and stage 1, crossing the 2 mg/L threshold commonly used to signal increased cardiovascular risk.
A review argues that a lack of analytically validated measurement systems is the primary obstacle to the clinical translation of RNA 5-methylcytosine (m5C) in cancer. Altered m5C pathways have been linked to tumor progression and therapeutic resistance, but only a small fraction of candidates have advanced toward clinically validated b...
Researchers have identified AsLOX2 as a key gateway enzyme that oxygenates α-linolenic acid to form a saclipin-related intermediate. The team then tested whether the intermediate could be converted into saclipins through a series of chemical reactions, demonstrating a practical route toward saclipin production.
A new study develops a model to compare benefit-package options under a constrained healthcare insurance budget, considering clinical efficacy and household out-of-pocket expenditure. The model, TPCPSO_BD, performs better than comparison algorithms in small, medium, and large test cases, reducing direct household expenditure by 48.97%.
A nationwide study found diamide insecticides in 47 Chinese cities, with concentrations ranging from undetectable to 119 ng/L, and a national median of 40 ng/L. The study highlights regional pollution patterns and unexpected exposure risks to human populations, particularly children.
A new study from Toho University found that wearable robot training improved walking distance in patients with ALS by nearly 12 meters in a two-minute test, while quality of life remained stable. The study suggests that walking performance may improve without a measurable decline in quality of life, but larger controlled studies are ne...
A new laboratory study uses large-amplitude oscillatory shear and Fourier-transform rheology to track the shift from solid-like to fluid-like behavior in loess mudflows as deformation increases. The study identifies four strain markers that distinguish the linear regime, nonlinear yielding, and the solid-liquid crossover, with water co...
Researchers at TU Wien and MedAustron have developed a new approach combining carbon and helium ions to monitor tumor anatomy during treatment while destroying cancer cells. This method allows for reduced safety margins and spared healthy tissue, particularly near sensitive organs.
Research found that micro-nano bubbles increase redox potential, enhance carbon, nitrogen, and phosphorus cycling genes, and reduce greenhouse gas emissions in waterlogged soils. This technology provides a low-cost green remediation pathway for waterlogged farmland.
The Tree of Life programme aims to sequence the genome of every findable species in the UK and Ireland. The programme has introduced a new semi-automated process to publish and review genome notes, expanding access to research that supports advances in agriculture, conservation, and medicine.
A study by Anglia Ruskin University found that honeybees dominate wild pollinators when competing for food, restricting access to resources and physically displacing other species. The researchers recorded aggressive interactions initiated by honeybees, which often resulted in the loss of forage for other pollinators.
A study reveals drought stress is the primary factor amplifying Xylella fastidiosa's impact on almond trees, challenging the notion of natural environments as buffers against disease. Climate, water stress, and shrubland vegetation play a crucial role in disease spread and tree health.
A University of Bath study identified a paradox where consumers view businesses as more sustainable when they add eco-friendly items rather than removing them. The researchers found that people consistently reward visible eco-friendly additions but give little credit to businesses that reduce or remove products.
A nationwide Finnish registry study investigated medication-related osteonecrosis of the jaw in breast cancer patients receiving antiresorptive treatment. The study found that 12.6% of patients developed the condition, with associations between dental procedures and its risk. The findings emphasize the need for close collaboration betw...
Researchers identified fagopyrine, a naturally occurring compound in buckwheat, as a potential starting point for developing new AKT1-targeting drugs. The analysis revealed substantial variation in AKT1 expression across 33 cancer types, with increased expression linked to poorer outcomes in certain malignancies.
This comprehensive review synthesizes molecular mechanisms, current therapeutics, and emerging strategies in esophageal cancer. The findings highlight breakthroughs in immunotherapy and promising future directions in targeted therapies.
Research by the University of Warwick found that children born smaller than expected at birth tend to achieve lower scores in maths and reading, with the link persisting into mid-teens. The study of over 92,000 children suggests that monitoring a baby's growth and ensuring proper support is crucial for their development.
A joint team proposes a top-down strategy for controllable synthesis of chiral nanostructures in optical crystals using femtosecond laser pulses. This method enables the creation of chiral materials with unique optical responses, distinguishing between spin states of light, and has potential applications in encrypted optical communicat...
Researchers at GSI/FAIR successfully measured the chemical bond strength of seaborgium hexacarbonyl complex, finding a weaker bond than expected. The results contradict the trend of increasing bond strength in lighter homolog elements, attributed to relativistic effects.
Researchers propose recognizing recompensation as a distinct treatment-related disease state, distinguishing stable and unstable recovery, to better capture recovery and continuing risks after cirrhosis treatment. This framework could support more consistent research, clinical assessment, and long-term surveillance for patients recover...
Researchers at IIT have developed a new technology that introduces a switch into CAR-T cells, controlling their activation in response to cancer cells. This switch allows for precise control over the therapeutic genes, reducing side effects and increasing effectiveness against melanoma and breast cancer.
A computational model predicts that low red-to-far-red light ratios strengthen cold-responsive genes and low temperatures stabilize phytochrome proteins to promote cold tolerance. The model identifies phytochrome activity and the SlPIF4-SlGAI4 feedback circuit as potential control points for improving crop cold tolerance.
A new study by UConn researchers found that pitchers with reduced neck mobility are more likely to report arm problems and sustain pitching-related arm injuries. The study, which included 126 pitchers from seven collegiate teams, also found that those with reduced mobility lost more days out of play due to injury.
A 1970s-era fungal pathogen, believed to have originated in Asia, likely swept the globe, causing catastrophic declines in frog populations. Modern sampling shows that most species have recovered since the 1980s.
Researchers identified a molecular pathway that offers a new target for treatment, challenging a 30-year-old theory in cancer research. The study found that immune defenses may begin outside the cancer cell, creating an environment that prevents the immune system from attacking the cancer.
A new study reveals how RNA molecules, particularly lncRNA Gas5, influence the development of aggressive leukemia by forming biomolecular condensates. The research identifies several long non-coding RNAs associated with these structures and shows that Gas5 plays a key role in leukemia cell proliferation.
A team of researchers has discovered how a protein linked to cancer activates silent DNA regions, a mechanism that contributes to tumour development. The study, conducted in fruit flies, identifies collaboration between two proteins as a key requirement for activation.
The study links adolescent pornography consumption to problematic internet use, substance use, family conflict, and certain risky sexual behaviors. The research team proposes programs combining sex and relationship education, digital literacy, and substance misuse prevention to guide educational and preventative policies.
A new study assesses the impact of drifting buoys on weather forecasts during Storm Harry, which affected the Mediterranean region in January 2026. The buoys provided crucial atmospheric observations from areas with limited coverage, improving forecasts of heavy rainfall and rough seas.
Researchers at the University of Nottingham discovered how a common genetic mutation disrupts protein positioning during cell division, contributing to acute myeloid leukemia. They found that manipulating the chromosome periphery could help restore normal protein positioning and potentially complement existing therapies.
Researchers found that applying biomechanical tension to heart valves every time they beat helps protect collagen from breaking down, explaining why leaflets remain sturdy for decades. Increasing strain while preserving the natural strain ratio prevents collagen degradation, highlighting a biomechanical defense mechanism.
A new molecularly imprinted electrochemical sensor streamlines the quality control of lutein-rich products by detecting lutein dipalmitate and calculating the concentrations of other major lutein esters. The approach simplifies sample preparation, shortens analysis, and lowers the need for multiple standards.
Researchers at Princeton University have developed a novel combination of chemicals that reduces defects in perovskite solar cells, enabling them to retain energy from sunlight 10 times longer. This breakthrough could translate to a 1% improvement in power generation and pave the way for cheaper and more sustainable energy.
Researchers mapped gene regulators and identified NAC transcription factors associated with root development. The study suggests that hormone signaling and developmental regulation play a crucial role in root swelling, providing a foundation for molecular breeding to improve crop yield.
Pharma.AI's MMAI Gym enables scientists to adapt AI models to specific tasks, achieving performance matching or exceeding the state of the art across 70 chemistry and biology benchmark tasks. The company also introduced Generative Biologics, Chemistry42, and PandaOmics, providing tools for designing and predicting properties of molecul...
Researchers at the University of Bath have discovered a blueprint for designing powerful fluorescent materials, paving the way for better disease detection. The team developed a molecule that was five times brighter than the original azulene molecule, providing a promising candidate for future sensing and imaging applications.
Researchers found that the brain stores memories in an overlapping manner, which may help recall past threats quickly and respond to danger faster. This could be a survival strategy rather than a flaw, guiding therapeutic approaches to address rapid 'danger mode' transitions.
The 2026 State of the Climate report finds climate progress amid intensifying risks, with seven climate-related planetary vital signs at record extremes. The report warns of accelerating global warming, reaching 2°C above pre-industrial levels before 2050.
Art teachers adapted to online teaching during the pandemic, finding effective solutions to teach practical subjects. They used teaching patterns to overcome challenges, including generative artificial intelligence and design thinking. A prototype web tool was created to share these experiences, providing a resource for future art educ...
The American Society of Hematology has released new guidelines for managing myelofibrosis, a rare and life-threatening blood cancer. The guidelines recommend expanded molecular testing, early transplant referral, and appropriate use of JAK inhibitors to improve patient care and outcomes.
The Blue Zones Research Institute will advance the scientific study of human healthspan and lifespan extension by supporting new research on long-lived human populations. The Institute will make publicly available demographic data on Blue Zones, starting with a partnership with the Human Mortality Database.
A study in California's San Joaquin Valley has identified a geographic cluster of prenatally detected fetal defects. The research team analyzed fetal sonography reports from rural and urban communities, revealing a regional pattern that suggests potential environmental and other contributing factors.
The study reveals that maternity care's accessibility and coherence depend on cooperation between specialists, and that families often need practical guidance and emotional support. The research aims to ensure consistent support throughout the maternity journey, from pregnancy to postnatal period.
A newly discovered Jurassic fossil, Yuezhuornis yangyuanensis, challenges the traditional view of early bird evolution, revealing a complex process involving the exploration of different ecological niches. The fossil's unique anatomy, including serrated teeth and a hyperextensible second toe, suggests a terrestrial, flightless lifestyle.
Researchers will investigate the role of mitochondrial function in brain health and develop potential treatments for Alzheimer's disease. The study aims to identify biomarkers for mitochondrial health and explore lifestyle strategies to support brain health as people age.
Health Allies brings healthy aging teams into affordable senior housing communities to help older adults navigate the health care system and optimize their health and well-being. Residents tend to live at home longer, be better prepared to manage their own health, and live more fulfilled lives.
A recent study by Dr. Katie Matt and Daniel Hebert found an estimated $64 billion in fraudulent claims in the Paycheck Protection Program. The researchers recommend improved applicant verification, centralized fraud prevention efforts, and enhanced oversight to prevent similar fraud in future federal relief programs.
Researchers discovered that neutrophils signal intestinal epithelial cells to undergo apoptosis after reperfusion, disrupting the intestinal barrier. Blocking THBS1, CD36, or JNK reduces injury in a mouse model, suggesting a potential target for limiting gut barrier injury in severe burns and shock.
The Center for Grassland Ecosystem Forecasting (CGEF) will use in-situ observatories and advanced models to predict grassland ecosystem dynamics. The team will work with ranchers and land managers to develop actionable forecasts and tools, supporting regenerative practices and strengthening the STEM workforce.
Scientists discovered a novel microscopic mechanism that allows two metal alloys to remain damage-tolerant at 20 kelvin, or -253°C. This process involves nanoscale 'twinning' and a local transformation of the crystal structure, creating new sites for deformation and helping the metal absorb forces around a crack.
Researchers discovered that cancer cells under pressure trigger necroptosis, a type of programmed cell death, to stop spreading. Lower levels of MLKL protein may predict metastasis, leading to new biomarkers and treatments.
Researchers found that ancient sled dogs had 6% shorter leg bones than other similar species, which may have given them an advantage in pulling loads. This skeletal pattern could help identify possible sled dogs even with incomplete archaeological remains.