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Goethe University Frankfurt


How plants rot: New method decodes hidden decomposers of wood and leaves

A new bioinformatics-based method, fDOG, has been developed to search for genes with certain functions, including those involved in plant cell wall degradation. The study reveals a detailed global map of enzymes capable of degrading plant cell walls, with surprising discoveries among fungi and animals.

SourceGoethe University Frankfurt·JournalMolecular Biology and Evolution·TypeData/statistical analysis·DateAug 28, 2025

Megalodon: The broad diet of the megatooth shark

New research finds megalodon preyed upon a variety of species, including fish, sharks, and even crustaceans, contrary to the long-held belief that it targeted large marine mammals. The discovery was made by analyzing zinc isotopes in fossilized teeth, providing insights into the prehistoric shark's ecological versatility.

SourceGoethe University Frankfurt·JournalEarth and Planetary Science Letters·TypeExperimental study·DateMay 26, 2025

Neurodegenerative disease ALS: Cellular repair system could prevent protein aggregation

A team of researchers from Goethe University and Kiel University has discovered a way to prevent the formation of harmful protein aggregates in cultured cells. The study found that linking TDP-43 with SUMO prevents its aggregation, suggesting a potential new approach for treating ALS and other neurodegenerative diseases.

SourceGoethe University Frankfurt·JournalNature Chemical Biology·TypeExperimental study·DateApr 23, 2025

Building material for an ancient metropolis

Researchers from Goethe University Frankfurt and LEIZA aim to analyze 4,000 stamped bricks from the Roman period to gain insights into brick production and use in ancient Trier. The study may reveal previously unknown construction projects and provide a model for integrating archaeological and archaeometric methodologies.

Tuning forks in space: A final pure "tone" may reveal interior of neutron stars

Researchers have discovered a strong connection between the long ringdown phase of post-merger gravitational waves and the properties of dense regions in neutron-star cores. Analyzing this phase can significantly reduce uncertainties in the equation of state at very high densities, shedding light on what neutron stars are made of.

SourceGoethe University Frankfurt·JournalNature Communications·TypeComputational simulation/modeling·DateFeb 6, 2025

New impetus for female founders

The EXIST Women program aims to promote start-ups in the Rhine-Main region by supporting female founders. The program offers individual coaching, mentoring, and a strong network, as well as financial support of up to €3,000 per month. Participants benefit from workshops and coaching sessions that strengthen their entrepreneurial skills.

Slow editing of protein blueprints leads to cell death

A team of researchers has identified a mechanism that interferes with the splicing process in a more subtle way, leading to cell death. The study reveals that spliceosome subunits U4, U5, and U6 are normally stabilized by protein USP39, but when mutated or absent, stability is compromised, causing incorrect connections during splicing.

SourceGoethe University Frankfurt·JournalScience·TypeExperimental study·DateNov 14, 2024