A new type of DNA damage, glutathionylated DNA adducts, accumulates at high levels in mitochondrial DNA, affecting energy production and stress response. The discovery sheds light on how cells sense and respond to stress, with potential implications for diseases like cancer and diabetes.
A mouse study by University of California, Riverside scientists suggests microplastic exposure may accelerate the development of atherosclerosis in males. The study found microplastics dramatically worsened plaque buildup in male mice, but not females.
Researchers have successfully engineered functional brain-like tissue without animal-derived materials, opening doors to more controlled and humane neurological drug testing. The new material functions as a scaffold for donor brain cells and can be used to model traumatic brain injuries or neurological diseases like Alzheimer's.
In a study by Michelle Miner at UC Riverside, bumble bees were found to avoid foraging near ant colonies due to the risk of being bitten. However, aggressive bees who fought back were victorious in individual fights but may ultimately harm their colony by wasting energy.
Researchers at UC Riverside and City of Hope have developed a novel Pin1 degrading compound that suppresses pancreatic cancer peritoneal metastases. The treatment targets not only cancer cells but also tumor-supporting cells, potentially overcoming treatment resistance.
A study by University of California - Riverside professor Margaret C. Campbell found that consumers judge prices for essential goods not just through supply and demand, but also through their sense of morality. Companies perceived as taking advantage of vulnerable people may suffer long-term reputational damage.
Researchers discovered a common parasite of modern oysters has been infecting bivalves for hundreds of millions of years. The parasite, belonging to the spionid group, has remained largely unchanged despite multiple mass extinction events.
Scientists at UC Riverside are using advanced technology to understand how corals regain life-giving algae after suffering from heat stress. By studying the cellular and genetic mechanisms of algae reestablishment, researchers aim to develop practical tools to help reefs survive ocean warming.
Researchers at UCR have discovered a way to break salt-water bonds using high-frequency ultraviolet light, offering a non-photothermal alternative to traditional solar desalination systems. The breakthrough could reduce the need for energy-intensive saltwater treatment and address concentrated brine waste.
Huimin Zhang, a UC Riverside assistant professor, has received a $150,000 grant to study the role of HELIOS in epigenetic regulation of T cell aging and TFH cell differentiation. Her research aims to understand how aging affects the immune system and develop new vaccines and therapies to restore immune vitality in older adults.
Researchers at UC Riverside discovered that two toxic chemicals can form when propylene glycol is heated, harming human lung cells. The chemicals, methylglyoxal and acetaldehyde, disrupt cell functions and cause damage even at low levels.
Research from UC Riverside found that fit mice increased voluntary running activity when deprived of water. The study suggests that physical fitness may provide a physiological buffer against dehydration, which could be beneficial for humans in a warming world and individuals working in physically demanding outdoor occupations.
In her book 'Sonic Socialism: Crisis and Care in Pandemic Hanoi', Christina Schwenkel explores how Vietnam used sound technologies to inform, regulate, and connect people during the pandemic. The country's success was largely due to its rapid communication systems, including loudspeakers and public health videos.
Scientists found that breathing dusty air from the Salton Sea can alter the lung microbiome and trigger immune responses in mice. The study suggests that chronic exposure to such dust could have significant health effects, including asthma.
Scientists have identified two compounds, K102 and K110, that could promote remyelination and modulate immune function in multiple sclerosis. These compounds showed promising results in mouse models and human cells, suggesting potential for treating MS and possibly other neurological diseases.
A study by UC Riverside researchers identifies a strong connection between demyelination and seizure activity in multiple sclerosis. The findings suggest targeted treatments could address the root cause of seizures without suppressing overall brain activity.
Researchers developed a new diagnostic metric called State of Mission (SOM) to predict EV battery performance based on both battery data and environmental factors. SOM significantly reduced prediction errors compared to traditional methods.
A new report highlights how a California partnership, STOP COVID-19 CA, helped address health inequalities during the pandemic by bringing together researchers and communities. The network improved access to reliable information, testing, and vaccination, while laying the foundation for long-term health equity.
A 430-million-year-old fossil found in Wisconsin reveals that ancient leeches feasted on smaller marine creatures, challenging the assumption that they are bloodsuckers. The absence of a forward sucker in the fossil suggests a different early lifestyle for the group known as Hirudinida.
A comprehensive study by UC Riverside's School of Public Policy found that agricultural conservation programs saved water at a low cost per acre-foot, while new supply efforts were more expensive. The analysis showed that 80% of the Colorado River's water is consumed by agriculture, and incentive programs can deliver meaningful savings.
UC Riverside-developed FROSTI system allows precise control of laser wavefronts at extreme power levels, opening a new pathway for gravitational-wave astronomy. This technology expands the universe's view by a factor of 10, potentially detecting millions of black hole and neutron star mergers with unmatched fidelity.
A new study in mice found that concussions sustained early in life can lead to subtle brain changes that re-emerge later in life. The research highlights the importance of long-term monitoring and care following head injuries in children, as even mild symptoms may not be immediately apparent.
Researchers at UC Riverside discovered a carbon burial process in the ocean that can cause Earth's temperature to overshoot and cool down, potentially triggering an ice age. The study suggests that the planet's thermostat is not functioning as expected due to changes in atmospheric oxygen levels.
A team of international researchers, led by UC Riverside's Scott Pegan, are developing protective antibodies against CCHFV using monoclonal antibody treatments and exploring non-traditional viral targets. The study aims to identify life-saving therapeutics for future nairovirus outbreaks.
Research by University of California, Riverside physicist Roya Zandi reveals how viruses form highly symmetrical icosahedral structures around their genomes through a process of self-correction, driven by protein elasticity. This study could lead to designing synthetic nanocontainers for medical and biotech uses.
The University of California - Riverside is receiving a $2 million grant to investigate how gut microbes interact with their human hosts to influence health. The research aims to create next-generation probiotics that strengthen the gut microbiome, improve vaccine effectiveness, and prevent infections.
Armida Labs will use the funding to advance preclinical studies of Targefrin, a potential clinical candidate for pancreatic and other cancers. The grant aims to develop an anti-metastatic agent that targets the EphA2 protein, which drives cancer cell invasion and metastasis.
As Arctic permafrost thaws, geochemical reactions unleash metals like cadmium, harming fish and disrupting ecosystems. The Salmon River's transformation poses indirect threats to Indigenous communities and other species.
Researchers at UCR have developed a method to preserve AI safeguards in open-source models by retraining internal structure to detect and block dangerous prompts. The approach avoids external filters or software patches, instead changing the model's fundamental understanding of risky content.
A new study found that gossiping within couples is strongly related to happiness and, to a lesser extent, relationship quality. Gossip serves as a form of emotional bonding, reinforcing the perception that partners are on the same team, contributing to overall well-being.
A team of computer scientists at UC Riverside has developed a method to erase private and copyrighted data from artificial intelligence models without needing access to the original training data. The approach enables AI models to 'forget' selected information while maintaining functionality with remaining data.
Researchers at the University of California, Riverside, have made a breakthrough in building larger and more reliable quantum computers by linking multiple quantum chips. The team found that even imperfect links between quantum chips can produce a functioning fault-tolerant quantum system.
Researchers propose that Jupiter-sized exoplanets may accumulate and collapse into detectable black holes due to dark matter. This process could potentially generate multiple black holes in a single exoplanet's lifetime, making exoplanet surveys a promising method for hunting superheavy dark matter particles.
A new study by UC Riverside-led researchers finds that nostalgia serves as a bridge between employees' pre-acquisition identity and post-acquisition reality. The research suggests that understanding and leveraging nostalgia can help preserve organizational commitment and retain key talent during acquisitions.
A new study found that planting trees in tropical regions can cool the climate by up to 0.8° F and reduce fire risk, offering significant benefits for global temperatures and ecosystems. The research emphasizes the importance of location in determining tree planting's impact on climate effects.
A UCR-led study found that partisan gerrymandering undermines public faith in elections, leading to disillusionment and erosion of civic behavior. The research connects gerrymandering to broader perceptions of corruption, suggesting that even if a party wins, the victory can feel hollow due to perceived manipulation.
The report warns that immigration enforcement is a public health emergency for millions of children, causing constant anxiety and harm to their emotional development and academic performance. Clinical case studies reveal how trauma is transmitted across generations, shaping the mental health of immigrant children.
A national study calls for increased vaccine screening in emergency departments to address health inequities. The study found that nearly a third of the US population lacks primary care access and rarely receives vaccination screenings.
Researchers found that older adults who challenge themselves to learn new things are less likely to experience loneliness or depression, even during the COVID-19 pandemic. Continued skill learning is associated with improved mental health outcomes, including greater resilience to external stressors and reduced depressive symptoms.
Researchers have developed a three-dimensional imaging method to distinguish between two fundamental processes by which light is transformed into electric current in quantum materials. The breakthrough could lead to improvements in solar energy systems and optical communications technology.
A recent study from the University of California, Riverside, and the University of Wisconsin-Madison emphasizes the need for culturally responsive approaches to support healing among Latina college students who have experienced intimate partner violence. Resilient coping and social support were found to be strong predictors of well-being.
A new study by UC Riverside psychology scholars found that middle and high school students who voice higher expectations of success and perceptions of positive societal views are more likely to be interested in STEM careers. The researchers recommend introducing diversity into science education and encouraging exploration and creativity.
Researchers create AI model called UNITE that detects fakes by analyzing faces and backgrounds, making it one of the first tools capable of identifying synthetic or doctored videos. The system can flag a range of forgeries, from simple facial swaps to complex fully synthetic videos.
Researchers developed a chemical probe that binds to damaged mitochondrial DNA, blocking enzymatic processes that lead to its degradation. This approach lessens mtDNA loss, preserving energy production in vulnerable tissues. The new molecule successfully reduced inflammation and maintained functional DNA despite chemical tagging.
A study by University of California, Riverside researchers found that inhaling agricultural dust can alter the gut microbiome and impair intestinal function, leading to increased 'leaky gut' and associated chronic diseases. The study highlights the need for protective measures for agricultural workers.
Researchers have developed solid-state batteries that can charge in a fraction of the time and pack more energy into less space than traditional lithium-ion versions. These batteries use stable solid materials instead of liquid electrolytes, enabling faster charging, reduced safety risks, and improved efficiency.
A new study finds that cleaner air in East Asia, particularly China, has contributed to the recent acceleration in global warming. The region's aerosol reductions account for most of the observed warming since 2010, even after accounting for natural fluctuation events.
Researchers at University of California, Riverside, found that symmetrical silicon molecules can be fine-tuned for quantum electron behavior, turning conductivity on or off like a molecular-scale switch. This discovery could lead to ultra-small switches and thermoelectric devices, revolutionizing electronics.
New research reveals that plants rely on multiple heat-sensing systems and a sugar-based mechanism to detect temperature changes. Sugar produced in sunlight helps plants grow taller even when thermosensors like phytochrome B are less effective. This discovery could lead to breeding crops more resiliently under stress.
Researchers have made a breakthrough in understanding malaria parasite proteins that could lead to targeted therapies. Two key proteins, PfRAP03 and PfRAP08, regulate gene expression in the apicoplast, a unique organelle found in P. falciparum. The loss of either protein led to parasite death, confirming their essential roles.