The study found that TAVR resulted in significantly less structural valve deterioration after five years compared to SAVR. Patients with structural valve deterioration were at about twice the risk of death or rehospitalization as those without, highlighting the benefits of TAVR in reducing mortality and hospitalization risks.
A large study found that small to moderate-sized leaks after left atrial appendage occlusion (LAAO) procedures significantly increased the risk of adverse events such as clotting and bleeding in AFib patients. Researchers suggest optimizing device placement techniques and using newer devices may help minimize leaks and reduce stroke risk.
The SAVE program, a NIH initiative, provides real-time risk assessment of SARS-CoV-2 variants on immune protection. It uses a coordinated approach to identify and curate data about these variants, their impact on immunity, and their effects on vaccine protection.
Cedars-Sinai researchers created a clinical risk assessment algorithm that identifies patients at highest risk of treatable sudden cardiac arrest. The algorithm, based on 13 clinical, electrocardiogram, and echocardiographic variables, has the potential to enhance prevention and treatment options for this fatal condition.
A large prospective study found a positive association between higher avocado consumption and lower cardiovascular events. Avocados contain healthy fats and other favorable components that support good cardiovascular health.
A study identifies new biomarkers that predict the presence of subclinical atherosclerosis, providing a non-invasive way to detect cardiovascular disease. The research team analyzed blood plasma samples and validated three proteins as biomarkers, improving the prediction of cardiovascular risk.
Researchers analyzed nearly 100,000 pregnancies and found no association between COVID-19 vaccination and poor birth outcomes. The study provides further evidence on the safety of mRNA vaccines for pregnant individuals.
A Rutgers analysis of Medicare database found that two IV iron formulations have a much higher chance of provoking severe allergic attacks. The risk was highest for iron dextran and ferumoxytol, with rates three to eight times higher than ferric gluconate.
A study published in JAMA Network Open found that half of all women will experience at least one false positive mammogram over a decade of annual breast cancer screening with 3D mammography. The risk of false positives is lower for women screened every other year, and non-dense breasts also show a lower false positive risk.
Researchers have identified a blood biomarker called glial fibrillary acidic protein (GFAP) that may uniquely aid prediction of dementia in Mexican Americans. The study analyzed 745 participants over four years, finding that higher levels of GFAP predicted increased risk of developing dementia.
A post-hoc subgroup analysis of the AFIRE trial found that reduced kidney function significantly influences bleeding events during antithrombotic therapy. Patients with healthy kidney function have a decreased risk of bleeding over time, while those with reduced kidney function remain at high risk.
The BfR has developed a novel testing strategy to detect ciguatoxins in fish, which enables the reliable identification of seafood poisoning cases. This method combines cell-based assay tests and liquid chromatography-mass spectrometry (LC-MS/MS) for precise detection.
Research from the University of Minnesota found that lower left atrial function was associated with higher risk of developing dementia. Atrial myopathy, characterized by abnormal left atrial function and size, was identified as an independent risk factor for dementia.
A new study from the University of Illinois suggests that whether adolescents believe drug use is wrong has twice the magnitude of impact compared to other risk and protective factors. This finding highlights the importance of instilling a negative belief about drug use in young people as a key strategy for preventing substance use.
Researchers at UBCO's School of Engineering have developed a new, faster method for analyzing toxic waste materials using fluorescence spectroscopy and convolutional neural networks. This method can detect key toxins such as naphthenic acids in oil sands samples, providing a low-cost alternative to current methods.
Researchers used a contrast pattern mining algorithm on publicly available data from 16,000 participants in the T1D Exchange Clinic Registry. The study found individuals with an immediate family history of Type 1 diabetes were more frequently diagnosed with hypertension and other co-occurring conditions.
A Kaiser Permanente analysis found that pregnant patients with COVID-19 were at twice the risk of poor outcomes, including preterm birth and venous thromboembolism. The study also showed a significant increase in severe maternal morbidity, including conditions such as acute respiratory distress syndrome and sepsis.
Scientists discovered that earthquakes influence tectonic plate movement, altering frequency and patterns of quakes. This finding suggests improved earthquake risk models can be developed by incorporating feedback mechanisms after an earthquake.
A new study found that nearly half of over-35s lack confidence in recognizing cardiac symptoms during strenuous exercise. The survey of 153 Masters football players aged ≥35 years highlights the importance of education and knowledge in mitigating serious cardiac risk.
A new smartphone app developed by Scripps Research calculates genetic risk for coronary artery disease and finds that users at high risk are more likely to start using statins or other cholesterol-lowering therapies. The app, called MyGeneRank, uses genetic data from 23andMe and outputs a CAD risk score.
A study of California state prison staff found that COVID-19 vaccination rates were lower among workers compared to incarcerated individuals, resulting in increased risks of further outbreaks. The plateaued vaccination rates posed significant concerns for continued transmission from prisons to surrounding communities.
A study of nearly 600,000 adults found that those diagnosed with bipolar disorder, schizophrenia, or schizoaffective disorder had a higher risk of cardiovascular disease at younger ages. This highlights the importance of addressing cardiovascular risk factors for these individuals as early as possible.
A study from University of South Australia found that reading aloud to children can triple a child's resilience at school, particularly for those who have suffered abuse or neglect. The study identified reading as a key factor in supporting children's emotional, social and physical development before they start school.
A study led by University of Illinois Chicago researchers found that structural racism can result in poorer leukemia outcomes for Black and Hispanic patients. Neighborhood disadvantage was a significant predictor of leukemia-specific death, accounting for nearly all the Black-white disparity in AML-related death.
A retrospective analysis found that socioeconomically disadvantaged older adults are at a higher risk of decline in function and cognition after an intensive care unit hospitalization. The study highlights the need to prioritize low-income seniors in rehabilitation and recovery efforts after critical illness.
A new study developed an algorithm estimating a person's risk of developing prostate cancer based on age and two prostate cancer markers. The approach was found to reduce the number of false positives by three quarters compared to a standard PSA test while catching the same proportion of cancers, making screening safer and more accurate.
A meta-analysis of 15 studies found that taking more daily steps helps lower the risk of premature death, with benefits seen in adults younger and older than 60. The study suggests that walking at least 6,000-8,000 steps per day for older adults and 8,000-10,000 steps per day for younger adults may be optimal for longevity.
A study of nearly 312,400 adults found that consuming wine with meals was associated with a lower risk of developing type 2 diabetes. The analysis suggested that moderate drinking may have health benefits for glucose metabolism, but the exact mechanism is unclear.
A large international study assessed patients undergoing heart surgery and measured troponin levels before and after surgery. The findings showed that higher troponin levels are associated with an increased risk of death within 30 days, enabling healthcare teams to monitor patients more effectively.
A new study offers a framework for addressing cyber security challenges in critical infrastructure by explicitly representing multiple dimensions of potential impacts. The proposed Bayesian network model allows for the identification of optimal portfolios of security measures to minimize expected cyberattack impacts.
A recent study published in Acta Obstetricia et Gynecologica Scandinavica has found that severe COVID-19 in pregnancy is associated with a higher risk of adverse outcomes, including preterm birth and stillbirths. The research highlights the importance of vaccination against severe disease to protect both mothers and babies.
Researchers warn of substantial risks associated with AI in agriculture, including cyber-attacks and environmental degradation. They suggest involving ecologists in technology design to avoid scenarios like overuse of fertilisers and soil erosion.
A new hourly high-resolution precipitation dataset, ERA5@2km, has been developed using reanalysis over 20 European cities for the recent past thirty years. The dataset provides a basis for impact analysis at city scale, in terms of extreme hourly precipitation.
A study by Texas A&M researchers found that navigation systems frequently guide drivers to take paths with a greater risk of crashes, despite reducing travel time. The study analyzed road and traffic characteristics in five metropolitan areas and proposed a new system architecture for finding the safest route using navigation systems.
A study of 37,000 children in Vancouver found a significant association between air pollution and ADHD, as well as the protective effects of green spaces. Children living in areas with higher PM2.5 exposure had an increased risk of ADHD, while those in greener neighborhoods had a lower risk.
Researchers at University of Missouri found a long-term association between adolescent psychological well-being and adult cardiovascular disease risk. People who are more optimistic in their youth can lower their chances for heart disease as adults.
Experts recommend individualised multidisciplinary risk assessment for patients requiring elective surgery within 7 weeks of SARS-CoV-2 infection, considering baseline mortality risk calculation and surgical factors. Patients with persistent symptoms or moderate to severe COVID-19 may require longer delays than 7 weeks.
A new study found that assisted reproductive technology (ART) is independently associated with an increased risk of cardiovascular and pregnancy-related complications. Women conceiving through ART may be at higher risk of high blood pressure during pregnancy and future cardiovascular disease.
Researchers used AI to predict flood damage in the US, finding a high probability of flood damage for more than 1.01 million square miles across the country. The study suggests that recent FEMA maps do not capture the full extent of flood risk, with 84.5% of reported damage not within high-risk flood areas.
A new study from the University of Helsinki found that providing individuals with their personal genetic risk for cardiovascular disease motivates them to take better care of their health. The interactive web-tool KardioKompassi helped participants understand their risk and make lifestyle changes.
A recent study published in Frontiers in Toxicology found that heated tobacco and vape next generation products display reduced cardiotoxicity potential relative to combustible cigarette smoke. Heated tobacco aerosol showed some cardiotoxic potential, while vape aerosol exhibited no cardiotoxic effects even at high concentrations.
Annual MRI screenings starting at ages 30-35 may reduce breast-cancer mortality by more than 50% among women who carry certain genetic changes in three genes. The predictions involve pathogenic variants in ATM, CHEK2 and PALB2 genes – which collectively are as prevalent as the much-reported BRCA1/2 gene mutations.
A new 10-year analysis shows that only half of individuals with high blood pressure, high cholesterol, or obesity receive lifestyle support from their GPs. Lifestyle interventions can significantly reduce the risk of cardiovascular disease.
SourceSAGE·JournalJournal of the Royal Society of Medicine·TypeData/statistical analysis·DateFeb 17, 2022
A recent study found that exposure to complex mixtures of endocrine disrupting chemicals during pregnancy can impact children's brain development and language acquisition. The research, conducted in collaboration with multiple institutions, used a novel approach linking human population studies with experimental cell and animal models.
A VA research team found increased risks of mental health disorders, including depression, anxiety, and sleep disorders, in individuals who had COVID-19 infection. The study analyzed medical records of nearly 154,000 patients with COVID-19 and compared them to over 11 million people without COVID-19.
A new scoring system, MIAAH, accurately identifies patients at highest risk of death and those likely to survive from alcohol-associated hepatitis. The tool incorporates laboratory variables and demographic data, offering a valuable prognostic model for clinicians.
A study found that using two cannulas to place newborns in respiratory failure on life-sustaining ECMO increases mortality rates. The safest path is a single cannula in the right internal jugular, which can remove oxygen-poor blood and add oxygen before returning it to the baby.
A new study found COVID-19 hotspots in Canadian cities are concentrated along social determinants of health, including visible minority status. Prioritizing public health supports to specific neighborhoods can help curb transmission and improve pandemic response.
A new study examines the toxic impact of bio-based substances and innovative technologies on the environment, finding both biosurfactants and microgels as highly promising candidates for use in sustainable products. The results highlight the importance of integrating green toxicology into bioeconomy strategies.
A new study by Dr. Brian Stansfield and Dr. Jessica Gancar found a clear linear relationship between mortality and red blood cell transfusion volume in newborns on ECMO, with a 14% decrease in survival chances for every transfusion. The study suggests that reducing transfusion volumes may improve outcomes.
An international research team has assessed European vascular plant species and found that 7-9% are globally endangered. This study addresses the significant data gap in global Red List of Threatened Species, with nearly 90% of known plant species lacking threat assessments.
Patients with severe coronary artery calcium have a significantly increased risk of major adverse cardiovascular events during thoracic radiation therapy for non-small cell lung cancer. The study found that patients with severe coronary artery calcium had a 21.4 times increased risk compared to those with no coronary artery calcium.
A recent study revealed that current tomato cultivars are vulnerable to the emerging ToBRFV, a damaging virus affecting tomatoes and other crops. The research also developed a molecular detection tool to identify infectious virus particles carried on contaminated seeds.
A recent study found that protracted inflammation following COVID-19 is strongly linked to long-term changes in lung structure and function. Monitoring patients for signs of inflammation after infection may help identify those at risk of long-term lung problems.
A new Stanford University study reveals that communities near the West's wildland-urban interface are vulnerable to wildfires due to drought-sensitive ecosystems. The research identifies 18 'double-hazard' zones where plant-water sensitivity and atmospheric dryness create high wildfire risks.
A study published in Applied Economics analyzed the relationship between precious metal commodities and equity markets, revealing that gold and aluminum are the most desirable metals for investment. The research also found that copper and zinc have the largest spillovers on global equity indices.
A study published in Risk Analysis found that individuals who endorse libertarianism and anti-egalitarianism attitudes are more likely to disregard COVID-19 risks. This suggests that simply identifying as liberal or conservative may not capture the full scope of political ideology's impact on attitudes toward science issues.
A new European report reveals a massive treatment gap and disparities in osteoporosis care, with significant economic burden and projected increases in fragility fractures. The report emphasizes the need for improved service provision and uptake, particularly in countries with high disease burdens.
A Dartmouth study reveals that consumers using at-home COVID-19 self tests may misinterpret the implications of their test results, leading to either unnecessary or inadequate quarantine. The study suggests that individuals at high risk for infection should still quarantine after a negative test result.
A new study predicts that climate change will lead to a 26.4% increase in flood losses in the US by 2050, with African American communities facing the greatest risk. The research, published in Nature Climate Change, used advanced modeling techniques to analyze nationwide property data and flood projections.