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Study shows both natural variation in ACE concentrations and lowering blood pressure with ACE inhibitors are associated with lower risk of type 2 diabetes

A new study found that using ACE inhibitors to lower blood pressure is associated with a 24% reduced risk of developing type 2 diabetes. Natural genetic variations in ACE concentrations are also linked to lower T2D risk. The researchers used Mendelian randomization to infer the causal effects of ACE inhibition on T2D risk.

Coffee may protect against gallstones

A new study published in Journal of Internal Medicine found that coffee consumption is linked to a lower risk of developing symptomatic gallstones. Drinking more than six cups of coffee per day was associated with a 23% reduced risk, while one extra cup per day had a 3% lower risk.

SourceWiley·JournalJournal of Internal Medicine·DateSep 5, 2019

New study confirms protective effect of diabetes drugs against kidney failure

A new meta-analysis found that SGLT2 inhibitors can reduce the risk of dialysis, transplantation, or death due to kidney disease by about 30% and also reduce the risk of acute kidney injury. The results are encouraging for people with diabetic kidney disease, offering a new treatment option to halt disease progression.

SourceGeorge Institute for Global Health·JournalThe Lancet Diabetes & Endocrinology·DateSep 5, 2019

Researchers find alarming risk for people coming off chronic opioid prescriptions

Researchers discovered that patients coming off chronic opioid prescriptions were three times more likely to die of an overdose in the years that followed. This alarming outcome has raised concerns about the policy recommendations aimed at reducing opioid prescribing, highlighting the need for systems to protect patients.

SourceUniversity of Washington School of Medicine/UW Medicine·JournalJournal of General Internal Medicine·DateSep 5, 2019

Healthy lifestyle may offset genetic risk of dementia

A new study found that living a healthy lifestyle can significantly reduce the risk of dementia for individuals with a high genetic risk. The research, published in JAMA, analyzed data from over 196,000 adults and discovered that adhering to a healthy lifestyle, regardless of genetic risk, was associated with a reduced risk of dementia.

SourceUniversity of Exeter·JournalJAMA·DateJul 14, 2019

Vitamin D may not help your heart

A new Michigan State University study found that taking vitamin D supplements did not decrease the incidence of heart attacks, strokes or other major adverse cardiovascular events. The study of over 83,000 patients showed no benefit from vitamin D supplements in reducing cardiovascular risk.

SourceMichigan State University·JournalJAMA Cardiology·DateJun 19, 2019

Patients at a reduced risk of venous thromboembolism and persistent pain after partial versus total knee replacement

A study published in EULAR 2019 found that patients with osteoarthritis who undergo partial knee replacement have a 25-50% lower risk of venous thromboembolism, but an increased risk of revision compared to total knee replacement. The long-term benefits of partial knee replacement are offset by the higher risk of revision.

Extending sleep may lower cardiometabolic risk

Extending sleep duration has been associated with improved insulin sensitivity and reduced appetite for sweet and salty foods. Higher total sleep time was linked to lower caloric intake from protein and decreased overall sugar consumption.

SourceWiley·JournalJournal of Sleep Research·DateJun 5, 2019

Eating blueberries every day improves heart health

A new study published in the American Journal of Clinical Nutrition found that eating 150g of blueberries daily reduces the risk of cardiovascular disease by up to 15%. The research team from the University of East Anglia discovered that blueberries have a positive effect on metabolic syndrome, a condition affecting 1/3 of westernized ...

SourceUniversity of East Anglia·JournalAmerican Journal of Clinical Nutrition·DateMay 30, 2019

Study finds that quitting smoking during pregnancy lowers risk of preterm births

A Dartmouth-led study published in JAMA Network Open found that quitting smoking during pregnancy reduces the risk of preterm birth. The probability of preterm birth decreased by up to 20% if cessation occurred at the beginning of pregnancy. However, only about 25% of women who smoked prior to pregnancy were able to quit throughout the...

SourceThe Geisel School of Medicine at Dartmouth·JournalJAMA Network Open·DateApr 19, 2019

Replacing sitting time with physical activity associated with lower risk of death

A new study found that replacing a half hour of sitting time with light physical activity was associated with a nearly 50% reduction in mortality among the least active participants. Replacing sedentary time with moderate-intensity physical activity was also linked to a lower risk of death, although the association was smaller.

SourceAmerican Cancer Society·JournalAmerican Journal of Preventive Medicine·DateMar 25, 2019