Articles tagged with Fever
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A novel nairovirus, Yezo virus, has been identified in Japan causing a disease characterized by fever and reduced blood platelets and leucocytes. The virus is transmitted through tick bites and has been linked to at least seven human infections since 2014.
Researchers at WashU Medicine and University of Pittsburgh discover that Rift Valley fever virus uses a protein linked to cholesterol metabolism to infect cells. The finding could lead to therapies preventing or reducing the virus's impact by interfering with its entry into cells.
Researchers from University of Tsukuba found a decrease in COVID-19-related house call services due to lower seasonal flu activity, but an increase in severe cases. Hospital capacity strains during the pandemic contributed to this trend.
A case of multisystem inflammatory syndrome in an adult who recovered from COVID-19 is reported, highlighting the importance of considering this rare but possible complication. Prompt treatment helped recover the patient. The authors suggest encouraging reporting of cases to facilitate research and improve outcomes.
A new imaging technique, flexed elbow valgus external rotation (FEVER) view, has been shown to improve the evaluation of ulnar collateral ligament (UCL) injuries in Major League Baseball pitchers. This study found increased joint space width and diagnostic confidence with FEVER view compared to standard positioning.
Researchers have developed an antibody-based therapy to treat Crimean-Congo hemorrhagic fever virus, a highly lethal tick-borne disease. The therapy, called DVD-121-801, overcomes infection in mice with just one dose administered after virus exposure.
A study of 12,306 pediatric COVID-19 patients found that many children do not display typical symptoms such as fever and cough. The risk of hospitalization varies across racial/ethnic groups, with non-Hispanic Black and Hispanic children being at higher risk.
Rheumatic heart disease (RHD) in Africa can be controlled through increased coverage of interventions like early detection and cardiac surgery, saving around 70,000 lives by 2030. The PEN-Plus package of integrated disease management offers a high return on investment.
A new Strep A human challenge model has been successfully developed, paving the way to test vaccines against the common deadly bacteria that causes sore throats, scarlet fever and skin sores. The model, which deliberately infected healthy adult volunteers with the bacteria in a controlled environment, was found to be safe and effective.
A new commentary proposes that pulse oximeters be used instead of temperature checks for COVID-19 screening in older adults due to lower baseline temperatures and overlooked fever. This could help detect asymptomatic hypoxia and prevent infection progression, improving treatment outcomes.
Patients with glandular fever who have hospital contact are at a greater risk of developing depression, according to the largest study yet. The study found a 40% relative risk increase in depression after hospitalization for glandular fever, particularly among young people.
A new study by the University of California, San Francisco found that US adults with fever are often not tested for coronavirus, contributing to community transmission. The research suggests that increased access and timely testing could reduce the spread of the virus.
During the COVID-19 state of emergency, Kawasaki disease primarily affecting children saw a notable rise in pediatric admissions in Japan. The study investigated transmission modes, revealing a potential link between droplet or contact transmission and disease development.
A study of Italian close contacts found that older adults (60+) were 6.6% more likely to develop critical disease from SARS-CoV-2 infection compared to younger participants, who had a lower likelihood of severe symptoms.
US and UK digital COVID-19 symptom checkers failed to identify severe COVID-19, bacterial pneumonia, and sepsis, often advising patients to stay home. The study suggests that these symptom checkers may delay treatment for serious illness and confer an increased risk of morbidity and mortality.
A University of Arizona Health Sciences study estimates the total lifetime costs of valley fever for 10,359 patients in 2019 to be $736 million. The disease, caused by Coccidioides fungi, has increased prevalence and currently lacks a preventative vaccine or therapy.
A new study suggests that temperature scanners are unreliable for detecting Covid-19 due to false negatives and varying factors affecting skin temperature readings. Taking temperature readings from a person's fingertip and eye can provide a more reliable indicator of fever-induced changes in deep body temperature.
A new study finds that traditional surface temperature scanners are ineffective in detecting fever-related illnesses, like Covid-19. Instead, taking temperature readings from a person's fingertip and eye may provide more accurate results.
A smart ring wearable sensor detected COVID-19 symptoms in participants with subtle or unreported symptoms, suggesting its potential for early illness detection. The device's continuous temperature data and contextualized readings may lead to earlier isolation and testing, curbing infectious disease spread.
Researchers at UC San Diego used wearable devices to detect fevers in participants with COVID-19, showing promise for an early warning system. The study collected temperature data from over 50 participants and demonstrated that wearables can identify fever peaks more accurately than traditional spot checks.
A 48-year-old man with chest pain and body lice infestation was diagnosed with trench fever, a bacterial infection that can lead to endocarditis. Physicians should consider Bartonella quintana infection in unwell patients with a history of body lice infestation, given its association with homelessness.
A new study has uncovered DNA evidence of Bartonella quintana, the bacteria responsible for trench fever, in civilian remains dating back thousands of years. The discovery sheds light on the complex history of trench fever and provides insight into the lives of Christian citizens in Roman Syracuse.
Researchers identified VEXAS, a severe inflammatory disease caused by UBA1 gene mutations, revealing devastating consequences. The genome-first approach helped uncover the link between disparate diagnoses in patients with undiagnosed inflammatory conditions.
A new UK population study found that 86% of people who tested positive for COVID-19 did not exhibit specific symptoms such as cough, fever, or loss of taste/smell. The study suggests that widespread testing is needed to capture 'silent' transmission and prevent future outbreaks.
Researchers discovered a significant rise in scarlet fever cases globally, attributed to superantigen-toxin 'supercharged clones' of Streptococcus pyogenes bacteria. The toxin genes were acquired through viral infections, enabling the bacteria to better colonize and outcompete other strains.
A study found that patients with COVID-19 who presented within 3 days of symptom onset had more severe disease, including higher levels of organ failure, and were at increased risk for complications and death. Despite receiving antiviral therapy, mortality rates remained high in this group.
Researchers found that full-face readings provide greater accuracy than targeting only the inner canthi region for fever screening with IRTs. The study evaluated over 500 individuals and reported excellent IRT performance with clear correlations to oral temperature baseline data.
A recent study found that relying on symptom tracking apps to predict COVID-19 is inaccurate, highlighting the importance of laboratory testing. The study compared data from two studies and found that only specific symptoms like loss of smell and taste were reliable indicators.
A recent study by Rutgers researchers found only one Rickettsia rickettsii-infected tick out of over 3,000 examined in New Jersey. This discovery brings good news as the bacterium is extremely rare in the state, but its presence highlights the need for continued surveillance and research.
A major review of COVID-19 scientific literature confirms a cough and fever as the most common symptoms, with fatigue, loss of smell, and difficulty breathing also reported. The study analyzed data from over 24,000 patients across nine countries, ratifying the World Health Organisation's initial symptom list.
Infants under 90 days old who tested positive for COVID-19 mostly experience mild symptoms, with fever being the primary symptom. High viral loads were found in young infants despite mild clinical illness. The decision to admit to hospital is based on age, need for preemptive treatment and clinical assessment.
Researchers have identified conjunctivitis as a potential primary symptom of COVID-19, leading to changes in patient diagnosis and treatment protocols. Ophthalmologists are now taking extra precautions when treating patients with conjunctivitis and keratoconjunctivitis, including wearing personal protective equipment.
NHGRI researchers have identified genetic mutations associated with PFAPA syndrome, a periodic fever disorder that affects only children. The study reveals commonalities with other inflammatory conditions, including Behçet's disease and canker sores, and highlights the potential for new treatments and diagnostic tools.
King's College London researchers recommend adding loss of taste and smell to COVID-19 screening measures to detect almost 16% of missed cases. The analysis of 3.7 million users from the COVID Symptom Study app data found that loss of smell is a strong predictor of infection, occurring three times more frequently than fever or cough.
A new analysis published in Gastroenterology found that nearly half of individuals with COVID-19 experience changes in their sense of taste. Researchers suspect the true prevalence could be even higher due to limited symptom reporting.
Scientists have discovered that malaria's characteristic cycle of fever and chills is controlled by an intrinsic biological oscillator within the parasite. The study found that 87-92% of tracked genes were cyclical, providing strong evidence for an innate control mechanism.
A startup-developed AI system using facial recognition and thermal imaging detects fevers remotely in people near hospital front desks, alerting staff to potential COVID-19 cases. The system has been successfully implemented at Albert Einstein Jewish Hospital in São Paulo, Brazil.
Research suggests airborne transmission is a key factor in the spread of scarlet fever, with infected individuals shedding virus even without symptoms. The study found that classroom contacts were heavily infected and shed GAS despite being symptom-free, highlighting the importance of rapid diagnosis and treatment.
A study by UC San Diego Health found that patients with COVID-19 often experience profound loss of smell and taste, which is highly specific to the virus. The majority of patients recover their sense of smell within two to four weeks of infection.
A new experimental vaccine for African swine fever has shown promising results, with both low and high doses being 100% effective against the virus when challenged 28 days post-inoculation. The vaccine was developed to combat the highly contagious and lethal ASFV-G strain, which has been devastating Eastern Europe and Southeast Asia.
Researchers propose combining fever resistance with temporary tolerance promoted by controlled hypothermia for studying and treating severe conditions like sepsis. This innovative concept aims to understand human physiology's integrated defense strategies against infection.
African swine fever virus can replicate in various pig cells and has a relatively conservative genome. Whole-genome sequencing is crucial for understanding the transmission route of ASFV. Nanopore sequencing technology proved more efficient than traditional next-generation sequencing methods in obtaining viral genomes.
A new point-of-care diagnostic test has been developed using a biomarker called RC0497, which can differentiate infected individuals from healthy controls. The test shows promise in enabling early detection and timely treatment of this potentially deadly tick-borne disease.
Fever in cats is often caused by infectious agents transmitted through fleas, ticks, and sandflies. Consistent use of products that rapidly kill vectors or prevent bites is crucial to preventing these diseases.
A Brazilian team at FAPESP-supported Center for Research on Inflammatory Diseases identified the strategy used by immune cells to combat the pathogen Mayaro virus. The study provides a basis for the development of drugs against this disease, targeting the NLRP3 inflammasome and its role in producing proinflammatory molecules.
Scientists developed an investigational vaccine that protected cynomolgus macaques against Ebola, Sudan, Marburg, and Lassa viruses, all causing severe disease and death. The quadrivalent VesiculoVax vaccine showed promising results in a study published in the Journal of Clinical Investigation.
A vaccine for Lassa fever, a hemorrhagic disease causing up to 6,000 deaths annually, is set to enter human clinical trials. The measles platform-based vaccine demonstrated the best protection against the virus in preclinical tests.
A systematic review of over 2.1 million allergy sufferers found that each kilogram increase in birth weight is associated with a 44% increase in the risk of food allergies and a 17% increase in the risk of eczema. However, increased birth weight has no influence on the risk of childhood hay fever.
Researchers found that young infants with fevers are more likely to develop serious bacterial infections. Infants under eight weeks old have a doubled risk of developing such infections. Parents are encouraged to seek immediate medical attention if their child develops a fever over 100.4 degrees Fahrenheit.
A new study predicts climate change will cause Valley fever's range to more than double in size this century, reaching previously unaffected areas across the western U.S. The disease is expected to become more widespread in states like Colorado, Idaho and Oklahoma.
Scientists at University of California, Irvine predict that Valley fever will double in size this century due to climate change. The fungal infection is expected to become widespread in previously unaffected areas across the western U.S., including Montana, Nebraska, and Wyoming.
Scientists have identified a new strain of Streptococcus pyogenes causing more serious Strep A infections, including invasive diseases like bloodstream infections. The emm1 clone, M1UK, produces nine times more toxin than other strains, and its increased production may contribute to the severity of these infections.
A new strain of group A streptococcus bacteria, M1UK, has been identified as the dominant cause of Strep A infections in England and Wales since 2010. The strain produces more toxin than existing strains, potentially leading to increased cases of invasive infections.
Long-term data analysis reveals non-infected regions have a higher risk of infection due to seasonal changes in movement patterns. The study emphasizes the importance of focusing on specific individuals, seasons and areas to prevent future outbreaks.
A team at Colorado State University discovered that Culex tarsalis mosquitoes, a primary vector for West Nile virus, can transmit Rift Valley fever virus to livestock and humans in Colorado. The researchers found that these mosquitoes feed on both humans and livestock, making them a significant threat for potential outbreak.
Visceral leishmaniasis, transmitted by sand flies, can be prevented if diagnosed and treated early. Women in endemic regions face barriers to seeking care, leading to delayed treatment and increased mortality.
Researchers developed a new methodology to calculate vulnerability based on adaptive capacity, which can help international bodies allocate resources. The study found that the most vulnerable states are not necessarily those with high confirmed cases, but rather those that struggle to cope with the disease.
A California study reveals chronic Q fever cases may be more common than previously believed, with a higher case fatality rate than national averages. Meanwhile, a mass treatment campaign in Bolivia has effectively eliminated human fascioliasis, a parasitic worm disease once prevalent in up to 25% of the population.
A comprehensive study in Mexicali, Mexico, found that half of the neighborhoods had diagnosed human cases of Rocky Mountain spotted fever, with some areas having almost one in 10 infected ticks. The study also gauged residents' knowledge and found that fewer than half used pesticides to prevent bites.
Researchers at Harvard Medical School have uncovered a critical mechanism that enables segmented RNA viruses to replicate and survive. The discovery provides new potential targets for the development of antiviral drugs, which could help combat emerging and fatal viruses such as Lassa fever and Rift Valley fever.