Articles tagged with Infectious Disease Transmission
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
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Researchers developed a model to predict how locally tailored pandemic control measures can halt disease transmission and reduce societal burden. The study suggests that targeted interventions in subnational regions could have been just as effective as national lockdowns, resulting in fewer hospital admissions.
The U.S. laboratory system needs improvement to ensure timely and accurate diagnosis, tracking, and response to infectious diseases like COVID-19 and Mpox. The authors suggest government and private institutions collaborate to implement systemic changes, including federal funding and public-private partnerships.
Researchers have uncovered the ancient roots of a gene in wheat that provides resistance to the devastating Wheat Yellow Mosaic Virus, which causes significant economic losses. The discovery could lead to more resistant wheat cultivars, increased crop yields, and reduced use of harmful fungicides.
Researchers aim to optimize food bacterial detection using fluorescence detection, reducing detection time and improving sensitivity. The goal is to prevent spread of foodborne pathogens and provide a safe food supply.
Researchers have developed a potential treatment for autoimmune encephalitis by creating an NMDA receptor fusion construct that neutralizes pathogenic antibodies. This innovative approach has shown promise in reducing signal transmission to neurons and may lead to improved treatment options for patients with this rare and serious disease.
A review of studies found that rates of presumptive treatment for chlamydia and gonorrhea vary widely, with some areas treating up to 84% of patients while others treated less than 4%. The disparity highlights the need for standardized treatment guidelines and consideration of social determinants of health.
New research on malaria-infected bonobos shows that the infection harms them, too, with symptoms including fever and increased mortality risk. The study also finds that bonobos have a protective variant of an immune gene similar to one found in humans, suggesting a selective advantage for those individuals.
Researchers found that airborne particles carrying a mammalian coronavirus remain infectious for twice as long in drier air, thanks to the protective effect of saliva. The study suggests that managing indoor air filtration and ventilation is crucial to mitigate airborne disease spread.
A new Stanford-led study uses satellite and land use data to predict malaria outbreaks in Madagascar, providing insights into the disease's distribution and burden. The research identifies rural areas with flooded rice fields as high-risk zones for malaria transmission.
Researchers analyzed data on European travellers arriving from Africa between 2015 and 2019, finding malaria as the most common arthropod-borne disease. The study highlights the importance of using travellers' health data to complement local surveillance systems in Africa.
The US Preventive Services Task Force (USPSTF) recommends against routine serologic screening for genital herpes simplex virus infection, even in symptomatic individuals. The lifelong nature of HSV infection means there is no cure, but antiviral medications can provide clinical benefits to those experiencing symptoms.
Researchers estimated that three doses of Comirnaty and CoronaVac vaccines were 48% and 30% effective, respectively, in preventing Omicron infection. Boosters improved efficacy to 69% and 56%, but protection waned over time.
Scientists have developed a mouse model of mpox virus, revealing differences in virulence among genetic groups. The new model shows that the current outbreak strain, clade IIb, has a significantly lower mortality rate than previous strains.
In a study published in the Proceedings of the Royal Society of London B, researchers found that mandrill females pass on hygienic practices to their daughters, reducing parasite infection. This social transmission of hygiene has potential consequences for infectious disease dynamics in primate groups.
A severe begomovirus-satellite DNA disease complex has been detected in okra fields in the lower Rio Grande Valley area of Texas, posing a significant threat to cotton production. The complex involves the exotic cotton leaf curl Gezira virus and its associated satellite DNA molecules.
A real-time visual sensing system developed by researchers at Incheon National University can detect overcrowding with an accuracy of 96.55% in real-time. The system uses drones to capture footage, analyze it using a modified ResNet architecture, and feed the data into a social monitoring system.
A team of researchers used computational fluid dynamics to simulate the 3D spatial transmission of COVID-19 within a hospital isolation room. They found that the area above a patient's bed at a height of 0.7 to 2 meters is the highest risk zone for infection.
Researchers at Rice University have developed light-activated nanoscale drills that can kill pathogenic fungi, providing a potential new treatment option for fungal infections. The molecular machines target the mitochondria of fungal cells, disrupting cellular metabolism and leading to cell death.
A Rutgers researcher has analyzed data from Mexico's Ministry of Health to identify dengue fever hotspots, highlighting areas where severe outbreaks occur. The study found that lower socioeconomic status increases risk of dengue fever and that DENV-2 is the deadliest serotype.
A genomic study of the Seattle 2017-2022 Shigella outbreak revealed its origin as international travelers from areas where Shigella was common. The study also found that multi-drug resistant Shigella has become a growing global health concern, primarily affecting men who have sex with men and those experiencing homelessness.
A cohort study of over 600 persons with non-MRI-conditional implantable cardioverter defibrillators found that these devices continue to appropriately treat detected tachyarrhythmias after MRI scans. The findings suggest that patients with non-MRI-conditional ICDs can safely undergo MRI exams without compromising device function.
A new study finds COVID-19 was the top underlying cause of death from infectious disease among children and young people aged 0–19 years. The risk of death from COVID-19 was substantially lower compared to other age groups, but still a significant concern, with over 1,300 child deaths attributed to the virus in the US.
Researchers successfully treated a young man with recurrent non-gonococcal urethritis caused by Mycoplasma genitalium using chloramphenicol. The patient showed improvement after 14 days of treatment, despite initial failure with first and second-line antibiotics.
Researchers identified 7 key symptoms of long COVID, including heart issues and joint pain, in a study of 52,461 patients. The findings could help healthcare providers diagnose and treat the condition more effectively.
Researchers found that measles virus mutations in its fusion protein allow it to infect nerve cells, leading to subacute sclerosing panencephalitis. The team's discovery sheds light on the evolutionary mechanisms of viruses like coronaviruses and herpesviruses.
Researchers used CO2 sensors to assess airborne transmission risk in over 60 areas in a residential aged-care home. They found that staff areas were at high risk of transmission, but implementing ventilation measures reduced this risk.
Researchers found that high levels of mucosal IgA antibodies in the airways protect against SARS-CoV-2 infection for at least eight months, with a 90% lower risk of re-infection. Participants with prior infections generated stronger mucosal immune responses to Omicron breakthrough infections.
A systematic review found that livestock production is associated with improved height-for-age Z scores and weight-for-length/height Z scores in under-five children. However, it also increases the risk of disease transmission through water, food, and insects.
A recent study by University of Missouri researcher Jake Haselswerdt suggests that partisan beliefs do not overshadow how people perceive the severity of COVID-19 in their communities. Local public health information appears to get through to individuals, regardless of their political leanings.
Researchers discovered host proteins APOBEC3 can aid HIV's latency, a major hurdle to cure research. The finding raises questions about the role of these proteins and potential ways to block their activity to inhibit viral persistence.
A recent study found that medical professionals in Illinois were relatively knowledgeable about diagnosis and treatment of Lyme disease, but lacked information on other tick-borne diseases. The researchers are now designing a continuing education course to educate practitioners on current ranges of ticks and risk of disease.
A recent study found a significant decrease in influenza activity in China during the 2020-2022 COVID-19 pandemic, particularly in winter and spring. The observed reduction in influenza seasonality may be attributed to everyday COVID-19 public health interventions.
A study in California prisons found that recent vaccination and boosters significantly reduced infectiousness of COVID-19, with a 11% decrease per additional dose. Prior infection also provided protection, with a 23% risk of transmission compared to 33% for those who had never been infected.
A study found that children exhale fewer small particles, which are less likely to spread diseases like COVID-19. Larger particles produced by adults and children can transmit infections equally well, highlighting the importance of wearing high-efficiency masks for disease prevention.
A study found that acidification of aerosols post-exhalation significantly impacts viral load. Influenza A viruses are inactivated within minutes, while SARS-CoV-2 requires days at typical indoor pH levels.
A new study published in The Journal of Rural Health found that urban men who have sex with men (MSM) are more likely to get vaccinated and tested for Mpox than their rural counterparts. The study also revealed that rural MSM perceived themselves as less susceptible to the disease and had lower intention to be vaccinated.
A North Carolina State University study found that mosquitoes harbor diverse bacterial communities, including those associated with human diseases. The research revealed greater bacterial diversity internally than externally, suggesting that mosquitoes may transfer pathogenic bacteria through physical contact or defecation.
A new study examined the impact of Medicaid funding cessation on neonatal circumcision rates in California. The research found a significant decrease in circumcision rates, particularly among low-income families, which can exacerbate existing health disparities such as lower rates of sexually transmitted infections. The findings highli...
A new study by Boston University School of Public Health found that nearly 90% of deceased individuals at a Zambian morgue were infected with COVID-19, contradicting previous assertions that the virus spared Africa. The study suggests that the reported death toll in Africa is substantially higher than official records indicate.
A new study suggests that expanding Medicaid coverage in Houston, combined with increased use of PrEP and antiviral medications, could lead to a significant decline in new HIV infections among young Black gay, bisexual, and other men who have sex with men. The model projects a potential decrease in HIV incidence rate to almost 50% with...
A global study reveals that antimicrobial resistance genes in bacteria are driven by various factors, including geographic regions and hosts. The research identifies key genes conferring resistance to critically important drugs, shedding light on the mechanisms of transmission and the need for collaborative interventions.
New research reveals that bat virus relatives of MERS-CoV efficiently bind to bat ACE2 receptors as an entry point into cells. However, these viruses only weakly bind to human ACE2 cell receptors and are not known to cause disease outbreaks in people.
A large cohort study in Tanzania found that antiviral treatment can reduce the risk of HIV transmission from mother to child by 99.5%. The study suggests that achieving the World Health Organization's goal of eliminating mother-to-child transmission is possible with modern antiviral drugs.
The study of 12,600 adults in Hong Kong found that viral rebound was not associated with increased risk of mortality. Novel oral antivirals like molnupiravir and nirmatrelvir-ritonavir may be effective treatments for more patients with COVID-19 in the early phase of the infection.
A research team at Tohoku University developed a batteryless device that can detect COVID-19 particles in the air using magnetostrictive composite plates. The device operates without batteries and transmits signals wirelessly, making it suitable for integration with IoT technologies.
Researchers used computer simulations to show that SARS-CoV-2 variants can attach to host cells in both bats and humans using their spike proteins. The study's findings suggest a significant risk of mammalian cross-species infectivity, contradicting initial expectations of reduced transmission.
A systematic review of national clinical practice guidelines in Europe found that fewer than half include HIV testing recommendations for patients with medical conditions indicating HIV infection. This omission hinders efforts to stop the spread of HIV through timely diagnosis, affecting the lives of people living with HIV.
A study conducted in Brazil reveals that only 75.8% of under-fifteen children in São Paulo have antibodies against measles, falling short of the ideal 94% target to prevent outbreaks. The finding is a warning sign that Brazilian children are not achieving herd immunity, making them susceptible to infection.
A new study maps the global landscape of antimicrobial resistance, revealing surprising transmissions in Sub-Saharan Africa and highlighting the need for tailored strategies to combat resistance. The research, which analyzed sewage samples from 243 cities in 101 countries, found that resistance genes are more frequently transmitted acr...
A global Phase 2/3 clinical trial found that vaccination with SCB-2019 reduced the risk of transmitting SARS-CoV-2 infection to household members. The study showed a significant reduction in symptomatic cases among vaccinated household contacts and indicated that vaccines can play an important role in controlling future outbreaks.
Researchers develop a new method to track disease-carrying mosquitoes by ingesting harmless DNA particles, providing unique fingerprints of information. This innovative approach has the potential to revolutionize mosquito-borne disease surveillance and tracking, offering insights into mosquito movement and hotspots.
A new study found that a single dose of acoziborole is as effective as current treatments for sleeping sickness, with a cure rate of 95% for late-stage patients and 100% for early/intermediate-stage patients. The treatment could revolutionize treatment for the disease by eliminating barriers such as hospitalization and travel distances.
A mass testing pilot in Liverpool found a 25% reduction in COVID-19 related hospital admissions, preventing 6,829 infections and 239 hospital admissions. The study suggests large-scale voluntary community testing can reduce virus transmission and prevent hospital admissions.
A new model examines the interplay between epidemic spreading and information diffusion to understand how reliable info can be better disseminated during epidemics. Effective prevention practices and mass media can increase the epidemic threshold, making it harder for infections to spread.
Two WHO-recommended hand disinfectants have been shown to effectively inactivate the monkeypox virus, with ethanol and isopropanol concentrations of 40-60% being particularly effective. The critical factor in determining their efficacy is the concentration of these ingredients.
A systematic review of 36 studies found that influenza vaccination reduced the risk of SARS-CoV-2 infection by 20% and poor outcomes like ICU admission and death by 17-31%. The findings suggest that routine influenza vaccination could offer non-specific immunity against COVID-19 symptoms.
A recent study found that superbugs in the environment rarely transmit to humans, contrary to previous fears. The researchers discovered high levels of antimicrobial-resistant bacteria in livestock, pets, and environmental samples, but surprisingly little overlap between hospital and environmental strains.
Researchers at UC Santa Barbara discovered that the ecology of small mammals upon which ticks feed can explain rates of human Lyme disease in California. The study found a clear link between infected ticks and their frequent hosts, such as dusky-footed woodrats, with diverse species playing a role in transmission.
A global case series of monkeypox infection in cisgender and transgender women and non-binary individuals provides valuable insights into risk factors, routes of transmission, and clinical features. The study highlights the need for education among healthcare professionals to accurately diagnose and prevent transmission.
The number of Candida auris cases in the EU/EEA nearly doubled between 2020 and 2021, with 11% of cases having no available information on carriage or infection. Early detection is crucial to prevent the spread of this healthcare-associated pathogen.