Add BrightSurf on Google Email

HKUMed established the first human respiratory organoid culture system and unveils a novel mechanism for the high transmissibility of SARS-CoV-2 Omicron variant

A research team created the first human respiratory organoid culture system, enabling scientists to study COVID-19 and its variants. The study found that the BA.5 Omicron variant exhibits dramatically increased infectivity and replicative capacity in human nasal and airway organoids.

SourceThe University of Hong Kong·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateApr 20, 2023

Pediatric TB may affect lung functioning, growth later in life

A new study reveals that young children diagnosed with pulmonary tuberculosis are at an increased risk of subsequent wheezing, poor lung function, and reduced height and weight. The study found that children who developed PTB before six months old had more than double the risk of wheezing after 6 months.

SourceBoston University School of Public Health·JournalAmerican Journal of Respiratory and Critical Care Medicine·TypeObservational study·DateApr 18, 2023

Targeting nurse and patient ‘supercontactors’ in hospitals and long-term care facilities can help minimize spread of infectious diseases

Researchers found that identifying and targeting 'supercontactors', including nurses and patients with neurological disorders, can significantly reduce the incidence of MRSA colonization. Simulation studies showed that reinforced contact precautions and vaccination targeting these individuals can be more effective than random selection.

Preventing a measles outbreak: steps taken by London hospital to protect patients and staff potentially exposed to the virus

A London hospital recently took swift action to contain a potential measles outbreak, highlighting the importance of vaccination and prompt contact tracing. The hospital identified nine patients at high risk, including pregnant women and those with severe immunosuppression, and administered post-exposure prophylaxis to those not immune.

UK strep A research shows highest incidence of invasive disease has shifted from the most deprived groups to the second most affluent group

The highest incidence of invasive Group A Streptococcus (GAS) disease has shifted from the most deprived groups to the second most affluent group in the UK, according to new research. The emm1 strain, which causes severe disease, was more common in 2022 than previous years.

The first line of vaccines was highly effective at restricting COVID-19’s damage, according to a new Concordia study

The primary COVID-19 vaccines provided adequate protection against transmission, hospitalization, and death, but their effectiveness waned in the face of the Omicron variant. The study found that vaccines developed prior to Omicron's emergence were 83% effective against infection at baseline, but this decreased to 47% by 40 weeks.

SourceConcordia University·JournalThe Lancet Respiratory Medicine·TypeMeta-analysis·DateApr 13, 2023

NIH-funded study finds doxycycline reduces sexually transmitted infections by two-thirds

A new study published in the New England Journal of Medicine found that doxycycline can reduce the incidence of syphilis, gonorrhea, and chlamydia by two-thirds when taken within 72 hours after condomless sex. The research also highlighted a slight increase in antibacterial resistance, emphasizing the need for further exploration.

SourceNIH/National Institute of Allergy and Infectious Diseases·JournalNew England Journal of Medicine·DateApr 6, 2023

Less ‘risky’ sex of early pandemic still evident year after first lockdown in Britain

The early stages of the COVID-19 pandemic led to reduced opportunities for sex, with fewer reported unplanned pregnancies and abortions, but higher levels of sexual dissatisfaction and distress. The National Survey found that people were more likely to have multiple partners, but less likely to use condoms with new partners.

SourceBMJ Group·JournalSexually Transmitted Infections·TypeObservational study·DateMar 27, 2023

Frequent COVID testing of nursing home staff protected residents, saved lives

A new study found that frequent COVID surveillance testing protected nursing home residents by detecting infected staff earlier, disrupting transmission chains. The research showed that high testing frequency facilities had clinically meaningful reductions in resident cases and deaths, particularly before vaccine availability.

SourceUniversity of Rochester Medical Center·JournalNew England Journal of Medicine·DateMar 22, 2023

Hidden 'super spreaders' spur dengue fever transmission

A new study by Emory University researchers found that asymptomatic individuals account for a significant proportion (74%) of dengue infections in an Amazonian city. The 'super spreader' spaces, where infected people frequent, are crucial in predicting and controlling outbreaks.

SourceEmory University·JournalPNAS Nexus·TypeData/statistical analysis·DateMar 22, 2023

Defunding prevention and climate change drive rebound of malaria in Peru

A recent study found that malaria control programs in Amazonian Peru reduced the disease by 78% but saw a rebound when funding was cut, driven by climate change. Climate change has exacerbated malaria transmission, with rising temperatures and intense rainfalls contributing to the resurgence of the mosquito-borne disease.

SourceDuke University·JournalThe Lancet Regional Health - Americas·TypeObservational study·DateMar 21, 2023

Cases and transmission of highly contagious fungal infections see dramatic increase between 2019 and 2021

Cases of Candida auris, a highly contagious fungal infection, rose drastically between 2019 and 2021, with an increase in echinocandin-resistant cases. The findings emphasize the need for improved detection and infection control practices to prevent the spread of C auris.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeData/statistical analysis·DateMar 20, 2023

News coverage highlights some threats to deer conservation but may mislead or omit key information

A study analyzed news reports on Brazilian deer species between 2011 and 2021, finding that news coverage gave different weights to threats compared to the IUCN Red List. News items properly identified main threats like poaching and habitat loss but underestimated livestock diseases and overestimated road kill.

Bird flu associated with hundreds of seal deaths in New England in 2022, Tufts researchers find

A new study from Cummings School of Veterinary Medicine at Tufts University found that highly pathogenic avian influenza (HPAI) was associated with the deaths of over 330 New England harbor and gray seals. The virus was detected in birds and seals on the same beach, highlighting a potential route of transmission.

SourceTufts University·JournalEmerging Infectious Diseases·TypeObservational study·DateMar 15, 2023

Tune in, wash hands: COVID-19 TV coverage added momentum to hand hygiene boom

A new study from Osaka University found that COVID-19 TV coverage significantly increased hand hygiene compliance from 5% to over 70% in a matter of months. The researchers tracked the correlation between TV coverage and hand hygiene, finding a strong statistical connection between added airtime and increased compliance.

SourceOsaka University·JournalAmerican Journal of Infection Control·TypeObservational study·DateMar 14, 2023

Wheat’s ancient roots of viral resistance uncovered

Researchers have uncovered the ancient roots of a gene in wheat that provides resistance to the devastating Wheat Yellow Mosaic Virus, which causes significant economic losses. The discovery could lead to more resistant wheat cultivars, increased crop yields, and reduced use of harmful fungicides.

SourceUniversity of Melbourne·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMar 6, 2023

Putting out “the fire in the brain”

Researchers have developed a potential treatment for autoimmune encephalitis by creating an NMDA receptor fusion construct that neutralizes pathogenic antibodies. This innovative approach has shown promise in reducing signal transmission to neurons and may lead to improved treatment options for patients with this rare and serious disease.

SourceUniversität Leipzig·JournalBrain·TypeExperimental study·DateMar 3, 2023

Review of studies finds disparity in presumptive chlamydia and gonorrhea treatment rates despite CDC guidelines

A review of studies found that rates of presumptive treatment for chlamydia and gonorrhea vary widely, with some areas treating up to 84% of patients while others treated less than 4%. The disparity highlights the need for standardized treatment guidelines and consideration of social determinants of health.

SourceRegenstrief Institute·JournalSexually Transmitted Diseases·DateMar 1, 2023

Malaria infection harms wild African apes

New research on malaria-infected bonobos shows that the infection harms them, too, with symptoms including fever and increased mortality risk. The study also finds that bonobos have a protective variant of an immune gene similar to one found in humans, suggesting a selective advantage for those individuals.

SourceWashington University in St. Louis·JournalNature Communications·TypeExperimental study·DateFeb 23, 2023

Travellers as sentinels: what are the most common vector-borne diseases among European travellers arriving from Africa?

Researchers analyzed data on European travellers arriving from Africa between 2015 and 2019, finding malaria as the most common arthropod-borne disease. The study highlights the importance of using travellers' health data to complement local surveillance systems in Africa.

SourceEuropean Centre for Disease Prevention and Control (ECDC)·JournalEurosurveillance·TypeData/statistical analysis·DateFeb 16, 2023

Mandrills teach their daughters good hygiene practices

In a study published in the Proceedings of the Royal Society of London B, researchers found that mandrill females pass on hygienic practices to their daughters, reducing parasite infection. This social transmission of hygiene has potential consequences for infectious disease dynamics in primate groups.

SourceCNRS·JournalProceedings of the Royal Society of London·DateFeb 8, 2023