Family members of patients with coronary heart disease improved cholesterol levels, physical activity, and dietary habits after participating in a year-long intervention program. The program included counselling sessions, goal setting, and feedback, resulting in reduced body mass index and waist circumference.
SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateNov 18, 2013
Researchers developed a new system using 180 factors to calculate LDL cholesterol, providing a more accurate assessment for high-risk patients. The Friedewald equation underestimates LDL levels in nearly one out of four samples, leading to potential false reassurance and inadequate treatment.
A novel method to estimate LDL-C levels has been developed, providing more accurate risk classification for heart disease. The new approach uses a larger database of lipid profiles and applies an adjustable factor for triglyceride levels, resulting in improved accuracy, especially for patients with elevated triglyceride concentrations.
Researchers at UCLA found that engineered tomatoes can reduce the negative effects of unsaturated lysophosphatidic acids (LPAs) in mice, which are linked to high cholesterol and inflammation. The tomatoes produce a peptide that mimics HDL ('good') cholesterol, stopping increases in 'bad' cholesterol and inflammation.
SourceUniversity of California - Los Angeles Health Sciences·JournalJournal of Lipid Research·DateNov 13, 2013
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers from Boston University School of Medicine found that only about half of patients with newly diagnosed high cholesterol were screened for thyroid dysfunction. Current guidelines recommend TSH blood tests to rule out hypothyroidism in these patients.
SourceBoston University School of Medicine·JournalJAMA Internal Medicine·DateNov 13, 2013
The new guideline identifies four major groups of patients who will benefit from statin therapy to prevent stroke and heart attacks. Adopting a heart-healthy lifestyle is also crucial in preventing high blood cholesterol.
SourceAmerican College of Cardiology·JournalJournal of the American College of Cardiology·DateNov 12, 2013
A study found that replacing saturated fats with polyunsaturated oils like corn and safflower oil may not reduce heart disease risk. In fact, rates of death from cardiovascular disease increased in the treatment group. Health Canada should modify its health claim for omega-6 oils.
SourceUniversity of Toronto·JournalCanadian Medical Association Journal·DateNov 11, 2013
Analysis suggests replacing saturated fats with polyunsaturated oils like corn and safflower oil may not reduce heart disease risk, but rather increase it. Health Canada should modify health claims to exclude these oils.
SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateNov 11, 2013
Scientists have created a lab-made high-density lipoprotein (HDL) mimic that can be easily produced in large amounts, offering a potential new treatment for cardiovascular disease. The material is also being explored as a carrier for drug delivery and medical imaging applications.
SourceAmerican Chemical Society·JournalACS Nano·DateOct 30, 2013
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
An observational study found that testosterone treatment reduced total cholesterol, LDL, triglycerides, and increased HDL in hypogonadal men. Testosterone therapy also lowered systolic and diastolic blood pressure, suggesting a reduction in hypertension.
SourceBoston University School of Medicine·JournalInternational Journal of Clinical Practice·DateOct 23, 2013
A new consensus report highlights massive underdiagnosis and undertreatment of hereditary high blood cholesterol in virtually all countries, with the exception of Netherlands and Norway. Easy to diagnose through a blood test and family history, the condition can be treated with statins and a low-cholesterol diet.
SourceUniversity of Copenhagen·JournalEuropean Heart Journal·DateOct 21, 2013
A study found that mothers with high LDL cholesterol before pregnancy have a 5-fold increase in their children's risk of developing high cholesterol as adults. This risk factor may be influenced by epigenetic changes, highlighting the importance of managing cholesterol levels throughout life.
SourceHeart and Stroke Foundation of Canada·DateOct 17, 2013
Regular weight training may improve HDL function and protect against heart disease even in those who remain overweight. The study found that sedentary men had dysfunctional HDL compared to strength-trained men, regardless of body weight status. Fitness is a better measure of who has healthier functioning HDL cholesterol.
SourceAmerican Physiological Society·JournalJournal of Applied Physiology·DateOct 9, 2013
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
A new class of RNAi drugs has shown promising results in lowering cholesterol levels by up to 57% in healthy volunteers. The treatment, ALN-PCS, works by blocking the production of PCSK9, a protein that destroys low-density lipoprotein (LDL) receptors.
SourceThe Lancet_DELETED·JournalThe Lancet·DateOct 2, 2013
Recent studies suggest that moderate habitual coffee consumption is unlikely to adversely affect cardiovascular health. Higher green tea and coffee consumption has been inversely associated with the risk of CVD and stroke in the general population. Moderate coffee consumption may also have a favorable effect on plasma cholesterol levels.
Researchers found that pravastatin impaired learning and recognition memory in rats, while atorvostatin showed no adverse effects. The study suggests chronic treatment with pravastatin may cause cognitive impairment, but further studies are needed to confirm this.
SourceUniversity of Bristol·JournalPLOS ONE·DateSep 25, 2013
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Research reveals that high 'bad' cholesterol levels stimulate production of hematopoietic stem/progenitor cells, which promote inflammation and atherosclerosis. The study opens up a potential new approach to preventing heart attack and stroke by focusing on interactions between cholesterol and these cells.
SourceUniversity at Buffalo·JournalPLOS ONE·DateSep 23, 2013
A large DNA-sequencing study of anorexia nervosa has linked the eating disorder to variants in a gene coding for an enzyme regulating cholesterol metabolism. This finding suggests that anorexia could be caused by disruption in normal cholesterol processing, affecting mood and eating behavior.
SourceScripps Research Institute·JournalMolecular Psychiatry·DateSep 11, 2013
Researchers found platelet Golgi apparatus undergoes changes after acute cerebral infarction, influencing CD40L expression and platelet function. This discovery may lead to new therapeutic targets for treating cerebral infarctions.
SourceNeural Regeneration Research·JournalNeural Regeneration Research·DateSep 4, 2013
A randomized trial found that a fixed-dose combination medication for blood pressure, cholesterol, and platelet control resulted in significantly improved medication adherence after 15 months. The study also showed modest but significant improvements in systolic blood pressure and low-density lipoprotein cholesterol levels.
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
A variant of FGF21, LY2405319, has been shown to improve metabolism in obese humans with type 2 diabetes by reducing LDL cholesterol and triglycerides while increasing HDL cholesterol levels. The hormone also reduced body weight and fasting insulin, and increased adiponectin.
SourceCell Press·JournalCell Metabolism·DateSep 3, 2013
A study of 2,238 CAD patients found that statin treatment reduced the risk of major cardiovascular events across all three groups: very low, low, and high LDL-C levels. Statins also showed significant benefits regardless of LDL-C level, suggesting their potential to reduce cardiovascular risk for all CAD patients.
A study found significant differences in LDL-cholesterol target achievement between Germany and the UK, with UK patients receiving more potent statins and higher doses. The UK system's incentive-based reimbursement may drive aggressive treatment, while Germany's restrictive system leads to conservative treatment.
A recent study found that intensive lifestyle changes and metformin treatment reduced cholesterol levels and improved triglyceride profiles, lowering the risk of heart disease. The Diabetes Prevention Program analyzed over 1,600 participants, showing positive changes in blood particle distribution.
SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateAug 27, 2013
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
Researchers discovered a new genome-wide significant locus associated with infantile hypertrophic pyloric stenosis, a serious gastrointestinal condition. The study also found an inverse relationship between low cholesterol levels at birth and increased risk of IHPS in infants.
A new study found that middle-aged men are at a greater risk for having a first heart attack due to high cholesterol levels, unlike women who are also at risk but to a lesser extent. The study suggests that men with high cholesterol should be treated more aggressively to prevent infarctions and save lives.
SourceNorwegian University of Science and Technology·JournalEpidemiology·DateAug 16, 2013
Researchers at Boston University's National Emerging Infectious Diseases Laboratories have generated a map of the cellular circuitry of Mycobacterium tuberculosis, shedding light on its ability to survive inactive in the human body for decades and resist treatment. The study provides new insight into the bacterium's survival mechanisms...
SourceBoston University School of Medicine·JournalNature·DateJul 3, 2013
Researchers found that simultaneously controlling high blood pressure and cholesterol can significantly reduce the risk of heart disease. The study suggests that prescribing medications and regular doctor visits can greatly benefit certain populations, including older adults and Hispanic-Americans.
A Loyola University Medical Center study found that statin-intolerant patients who received specialized lipid clinic care had significantly reduced total and LDL cholesterol levels. In contrast, those not referred to a lipid clinic showed minimal improvement in their cholesterol levels.
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A study of 1076 preschool children aged 3-5 years found associations between unhealthy eating behaviors and serum non-HDL cholesterol levels, indicating a potential early link to cardiovascular disease. The research suggests that promoting responsive feeding and healthy eating habits may help reduce the risk.
SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateJun 17, 2013
A randomized clinical trial of flaxseed supplementation in children with hypercholesterolemia found no significant effects on total and low-density lipoprotein cholesterol levels. The study concluded that flaxseed remains an unverified strategy for managing cardiovascular risk factors in youth.
SourceJAMA Network·JournalJAMA Pediatrics·DateJun 3, 2013
Researchers at UC San Diego identified apoA-I binding protein as a key player in regulating blood vessel growth by removing excess cholesterol from endothelial cells. This process inhibits angiogenesis and can help prevent tumor growth.
SourceUniversity of California - San Diego·JournalNature·DateMay 29, 2013
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A healthy Nordic diet is shown to lower cholesterol levels and reduce inflammation associated with pre-diabetes. The diet's emphasis on local produce, whole grains, and lean protein sources contributes to its benefits.
SourceLund University·JournalJournal of Internal Medicine·DateMay 29, 2013
Researchers found that job stress is associated with an altered lipid profile, leading to higher rates of 'bad' cholesterol and lower levels of 'good' cholesterol. This can increase the risk of cardiovascular disease. The study analyzed data from over 90,000 workers and found a significant link between job stress and dyslipidemia.
SourceSpanish Foundation for Science and Technology·JournalScandinavian Journal of Public Health·DateMay 16, 2013
Researchers found that breathing motor vehicle emissions alters high-density lipoprotein (HDL) cholesterol, making it contribute to clogged arteries. The inhalation of emissions activates components of oxidation, leading to inflammation and hardening of the arteries.
SourceUniversity of California - Los Angeles Health Sciences·DateMay 15, 2013
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
A new study found that consumers are more likely to endorse certain responses on agreement scales when labels are familiar to them. This can lead to biased survey results if the labels are not equivalent across languages. Researchers recommend paying closer attention to response category labels to avoid such biases.
SourceUniversity of Chicago Press Journals·JournalJournal of Consumer Research·DateMay 14, 2013
A team of researchers led by Professor Jean Gruenberg has identified an exit in the cellular garbage truck, a structure responsible for sorting molecules and ensuring inter-cell digestion and regulation. The study reveals how Alix protein uses this route to avoid cellular digestion and how vesicular stomatitis uses it to infect cells.
SourceUniversité de Genève·JournalDevelopmental Cell·DateMay 9, 2013
Researchers found that whole walnuts and their extracted oil improve cardiovascular disease risk by favorably affecting vascular health and enhancing the functionality of good cholesterol, HDL. The study suggests that simple dietary changes incorporating walnuts or their oil in a heart-healthy diet may reduce the risk of heart disease.
SourcePenn State·JournalJournal of Nutrition·DateMay 8, 2013
A heart-healthy Mediterranean diet helped men at high risk for heart disease reduce their bad cholesterol levels by 9%, regardless of whether they lost weight. This finding suggests that the Mediterranean-style diet may be recommended for effective management of metabolic syndrome and related cardiovascular risks.
Exposure to secondhand smoke at home has been linked to lower levels of 'good' cholesterol in teenage girls, increasing their risk of heart disease. The study found that 17-year-old girls exposed to passive smoking had declined HDL cholesterol levels, making them more vulnerable to cardiovascular disease.
SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateApr 30, 2013
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Researchers discovered a naturally occurring protein that disrupts cholesterol levels in cell membranes, blocking virus entry. The findings have potential for developing anti-viral therapies targeting the endosome compartment.
SourceUniversity of Southern California - Health Sciences·JournalCell Host & Microbe·DateApr 17, 2013
Researchers discovered that high cholesterol levels can cause defective cell division, leading to Alzheimer's disease and atherosclerosis. Cholesterol disrupts the process of cell division, resulting in cells with incorrect numbers of chromosomes and genes.
SourceUniversity of Colorado Anschutz Medical Campus·JournalPLOS ONE·DateApr 15, 2013
Researchers at the University of Michigan identified a new potential therapeutic target for lowering cholesterol, inhibiting a gene responsible for transporting a protein that interferes with liver cell function. This approach preserved the liver's capacity to clear plasma cholesterol from the blood without affecting overall health.
African-Americans with a variant of the ABCA7 gene have nearly double the risk of developing late-onset Alzheimer's disease compared to those without the variant. The study, led by Columbia University Medical Center, suggests that lipid metabolism may play a more important role in Alzheimer's disease among African-Americans.
SourceColumbia University Irving Medical Center·JournalJAMA·DateApr 9, 2013
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
A new study finds that walking briskly can lower the risk of high blood pressure, high cholesterol, and diabetes as much as running can. Researchers analyzed data from over 33,000 runners and 15,000 walkers to find similar reductions in risk for these conditions.
A study published in Cell Metabolism suggests that macrophage cholesterol accumulation contributes to macular degeneration. Researchers found that eye drops could reduce blood vessel growth and prevent blindness by targeting cholesterol regulators.
SourceCell Press·JournalCell Metabolism·DateApr 2, 2013
Researchers found that age-related macular degeneration shares a common link with atherosclerosis due to impaired cholesterol efflux in macrophages. The study suggests that cholesterol-lowering eye drops or other medications could prevent vision loss caused by macular degeneration.
SourceWashU Medicine·JournalCell Metabolism·DateApr 2, 2013
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
A study published in Cell Metabolism suggests that targeting cholesterol metabolism in the eye may prevent severe age-related macular degeneration. Researchers found that macrophages play a key role in clearing cholesterol from the eye, and that with aging, these cells become less efficient at this task.
SourceNIH/National Eye Institute·JournalCell Metabolism·DateApr 2, 2013
Researchers at the University of Colorado Cancer Center have developed a new technology that uses cholesterol rafts to deliver genetic payloads into cancer cells. This innovative approach overcomes the long-standing challenge of delivering nucleic acids across cell membranes.
SourceUniversity of Colorado Anschutz Medical Campus·JournalTherapeutic Delivery·DateApr 2, 2013
A new study found that the standard formula used to calculate LDL cholesterol levels often underestimates accuracy, especially in desirable ranges. Researchers suggest using non-HDL cholesterol as an alternative to assess risk and determine treatment.
SourceJohns Hopkins Medicine·JournalJournal of the American College of Cardiology·DateMar 26, 2013
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Researchers characterized SUDEP in a mouse model of DS, finding that treatment with drugs reducing parasympathetic activity reduced incidence. Lymphatic vasculature also plays crucial role in cholesterol removal from arteries, with impaired lymphatic growth leading to increased cholesterol retention. A new therapeutic target is identif...
SourceJCI Journals·JournalJournal of Clinical Investigation·DateMar 25, 2013
Researchers have found that the lymphatic system is crucial for removing cholesterol from peripheral tissues, including artery walls. The study suggests that therapies supporting lymphatic transport could enhance cholesterol clearance and potentially treat atherosclerotic vascular disease.
SourceJCI Journals·JournalJournal of Clinical Investigation·DateMar 25, 2013
Researchers genetically engineered tomatoes to produce a peptide that mimics the action of good cholesterol, reducing inflammation and plaque build-up in mice. The study suggests that targeting the small intestine may be a new strategy to prevent diet-induced atherosclerosis.
SourceUniversity of California - Los Angeles Health Sciences·JournalJournal of Lipid Research·DateMar 19, 2013
Researchers have identified a new alternative to statins for patients who can't tolerate the side effects of cholesterol-lowering drugs. Pitavastatin was shown to lower bad cholesterol by an average of 34% and reduce the risk of heart attack, stroke, and death in up to 68% of patients with high cholesterol.
The HPS2-THRIVE study found that niacin therapy provides no benefit and may even be harmful for patients with vascular disease. The study showed a higher incidence of bleeding, infections, new onset diabetes, and gastrointestinal problems among those receiving the drug.
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Exposure to statin TV ads was linked to higher rates of high cholesterol diagnosis and statin use, especially among those at low risk for heart disease
SourceSpringer·JournalJournal of General Internal Medicine·DateMar 7, 2013
Researchers found that LDL cholesterol increases by an average of 7mg/dL in winter compared to summer, resulting in a 8% overall increase in high cholesterol prevalence. Seasonal variations in metabolism and behavior may contribute to these changes.
A study by 98-year-old researcher Fred Kummerow found that oxidized lipids contribute to heart disease by increasing calcium deposition on the arterial wall and interrupting blood flow. Oxidized cholesterol was also linked to an increased synthesis of a blood-clotting agent, thromboxane.
SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalAmerican Research Journal of Cardiovascular Diseases·DateFeb 27, 2013
Researchers at LSU Health Sciences Center have identified a new gene mutation causing Schnyder corneal dystrophy, a rare hereditary eye disease. The mutation is linked to vitamin K metabolism and may lead to the development of a new treatment using vitamin K supplements.
SourceLouisiana State University Health Sciences Center·JournalHuman Mutation·DateFeb 21, 2013
Researchers at the University of Gothenburg have made significant findings on the link between gut bacteria and cholesterol metabolism. The study reveals that gut bacteria can reduce bile acid synthesis in the liver by signaling through a specific protein, which could lead to new treatments for cardiovascular disease.
SourceUniversity of Gothenburg·JournalCell Metabolism·DateFeb 18, 2013
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.