Articles tagged with Arteries
Researchers at Vanderbilt University have found that endothelial cells in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue. This discovery could lead to new treatments for heart failure and repair after a heart attack, particularly in cases of coronary artery disease.
Researchers at USF and CUMC developed a novel microRNA-based strategy to selectively inhibit blood vessel re-narrowing while promoting vessel healing. The therapy achieved 80% endothelial cell coverage in rat models, reducing thrombosis and functional vascular responses.
New technique reveals correlations between arterial health and cognitive decline in older adults, highlighting the importance of cerebrovascular well-being for healthy aging. The study also explores the impact of stress on arterial stiffness and its consequences for brain function.
Researchers at the University of Leeds have identified a key gene involved in blood vessel formation, which may help understand how complex life begins. The discovery could lead to new possibilities for treating cardiovascular disease and cancer by targeting changes in blood flow.
A new study published in Menopause finds that lifelong soy consumption helps prevent atherosclerosis and improves cholesterol levels in premenopausal monkeys. After menopause, switching to a soy diet can also improve cholesterol levels, but has limited effect on plaque progression.
Research suggests that ancient cultures may have been plagued by atherosclerosis due to chronic infection, inflammation, or exposure to smoke. The study of mummies from various cultures reveals a high incidence of the disease, which contradicts the expectation that modern lifestyles are the primary cause.
A rare case of a posterior spinal artery aneurysm caused by Ecstasy use has been reported, highlighting the risk of severe complications from recreational drug taking. The teenager's symptoms worsened after a week, leading to an emergency transfer and successful surgery.
A pilot study found that participants with PAD increased their ability to walk unassisted after consuming dark chocolate rich in polyphenols. The improvements were modest but suggested a potential therapeutic strategy for countering cardiovascular complications.
A Northwestern Medicine study found that adults who adopt healthy lifestyle behaviors in their 30s and 40s can control and potentially reverse coronary artery disease. The study also showed that losing healthy habits as they age leads to a measurable negative impact on heart health.
The study found no difference in mortality rates between patients who received preoperative beta-blockers and those who did not. However, patients who received preoperative beta-blockers had higher rates of new-onset atrial fibrillation compared to those who did not.
A new study suggests cranial ultrasound is more sensitive and equally specific as temporal artery biopsy in diagnosing giant cell arteritis. The test has high predictive accuracy, making it a promising replacement for the current gold standard.
Researchers have found that coating stents with vitamin C could lower implant-related risks by inhibiting smooth muscle cell growth and encouraging endothelial cells. This technique could make stents safer for millions of Americans who receive them annually.
A new study found that a home-based walking program significantly improved walking ability in patients with clogged leg arteries, even 12 months after the program started. The program reduced symptoms of peripheral artery disease (PAD) and increased walking distance.
A study published in PNAS suggests that Kawasaki disease may be caused by airborne aerosols from northeast China, possibly related to the fungus Candida. The findings indicate a strong link between wind patterns and disease outbreaks in Japan, with Candida species identified as the dominant airborne fungus.
A new study by CU-Boulder reveals that an antioxidant called MitoQ can reverse the negative effects of aging on arteries, improving vascular function and reducing the risk of heart disease. MitoQ targets mitochondria, specific cell structures responsible for oxidative stress, and restores endothelial function in old mice.
A study reveals that women with peripheral artery disease (PAD) experience excellent treatment outcomes, with higher success rates compared to men. Despite having more severe symptoms, women performed just as well in minimally invasive procedures like angioplasty and stent placement.
Researchers developed a new ultrasound device that can identify vulnerable arterial plaques, which are more likely to break off and cause heart attacks or strokes. The device uses dual-frequency intravascular ultrasound technology to detect contrast agents, making it easier to highlight vulnerable plaques on ultrasound images.
Researchers used CT angiography to assess coronary artery plaque volume index (PVI) in asymptomatic diabetic patients. PVI was related to age, BMI, and duration of diabetes, highlighting the importance of obesity as a modifiable risk factor.
A new study by LA BioMed Research found that a calcium score can predict heart disease risk among adults with minimal or no known risk factors. Adults with low to moderate calcium scores were more likely to die from heart disease than those with no calcified plaque buildup.
A Johns Hopkins study reveals that long-term HIV infections increase the risk of plaque buildup in coronary arteries, regardless of other risk factors. The researchers found noncalcified and partly calcified plaques more prevalent in HIV-infected men, suggesting a higher risk of heart attacks.
A study found lower risks of heart attack, death, and procedures to re-open the artery in patients receiving drug-eluting stents followed by individualized blood-thinning medication. The results challenge existing guidelines for prolonged anti-platelet therapy after stent placement.
New studies confirm coronary artery calcium scans as a reliable indicator of long-term heart disease risk, outperforming other tests in low-risk patients. The tests have been shown to detect early signs of plaque accumulation and hardening of the arteries.
A study found that women who ate a diet high in fruits and vegetables as young adults were less likely to have plaque build-up in their arteries 20 years later. In contrast, men did not show the same benefit. The study's findings support the importance of developing healthy eating habits early in life.
A study of nearly 500 men found that nonsurgical prostate artery embolization improved symptoms by 72% at three years, while preserving fertility. The treatment, which involves blocking blood flow to the prostate, also showed promise in cases where the problem recurred.
Surgeons in France have successfully replaced aortic valves without opening the chest in two patients. This innovative technique, known as TEAVR, shows promise for improving quality of life by reducing chest trauma and enabling faster recovery times.
Researchers find that a novel approach to accessing the uterus, using the wrist instead of the groin artery, can significantly reduce pain and trauma for women undergoing uterine fibroid embolization. The transradial access technique allows patients to walk immediately after treatment, improving their experience.
A study evaluated the role of infliximab in treating Kawasaki disease, a condition that can lead to irreversible heart damage if not diagnosed or treated promptly. Infliximab treatment was found to be safe and effective in preventing coronary artery damage in children with Kawasaki disease.
Researchers aim to develop nanoparticles that target prostate cancer cells with a genotoxin drug. The nanoparticles will also promote healing in damaged blood vessels by mimicking platelets and catching circulating endothelial progenitor cells.
Researchers developed a catheter-based device with volumetric imaging, enabling better guidance for surgeons in the heart. The device, integrating ultrasound transducers with processing electronics on a single chip, allows for real-time 3-D images and significantly improves patient outcomes.
Researchers at Clemson University have developed sticky nanoparticles that can deliver drugs targeting damaged arteries, providing a new method to fight heart disease. The nanoparticles, coated with a sticky protein, latch onto damaged arteries and release drugs in slow fashion, reducing the need for surgical interventions.
African-Americans are 39 times more likely to die from a stroke after an infection compared to other ethnic groups. Infection promotes blood clot formation and fat buildup in arteries, contributing to higher stroke mortality rates among blacks.
Researchers found that individuals with consistently elevated blood pressure levels throughout early adulthood had a higher risk of coronary artery calcification, a key indicator of heart disease. The study identified five distinct blood pressure trajectories, and those who exhibited increasing or elevated BP levels over time had large...
Researchers at Cleveland Clinic have discovered a process by which high-density lipoprotein (HDL) loses its cardio-protective properties and promotes inflammation. The study identified the structure of dysfunctional apoA1/HDL and found that higher levels raise cardiovascular disease risk in patients.
A multicenter study found that a Mediterranean diet supplemented with extra-virgin olive oil or nuts significantly reduced the risk of peripheral artery disease. The study, published in JAMA, included over 7,400 participants and followed them for nearly five years.
A study published in JAMA found that coronary artery calcium (CAC) density is associated with lower risk of cardiovascular events. Researchers suggest re-evaluating the CAC scoring system to incorporate density and other variables, as dense plaques may be more stable than previously thought.
Researchers at Case Western Reserve University are developing imaging technology to improve treatment and survival rates for ischemic heart disease patients. The new technology uses high-speed computer analysis to help doctors determine if stents are restoring circulation as designed, reducing the risk of failure.
Researchers found that fetal umbilical veins exhibit stress relaxation and creep properties similar to those of middle cerebral arteries, making them a suitable alternative for reconstruction. These findings indicate that the fetal umbilical vein can be transplanted to repair middle cerebral artery injury with favorable outcomes.
A new study published in the European Heart Journal found that coronary artery calcium screening is an accurate and personalized assessment for individuals at high or low risk of a heart attack or death from coronary artery disease. The study used data from almost 7,000 adult participants and showed that 15% of those considered at very...
Researchers devised a mathematical model to improve treatment options for coronary heart disease (CHD), which accounts for 18% of US deaths annually. The model helps explain the factors governing drug release and distribution in drug-eluting stents, providing valuable insight into developing better treatments.
Researchers found that blood vessels in face transplant recipients reorganize themselves, creating new networks to ensure healthy circulation. This understanding could improve surgical planning and assessment of potential complications, potentially shortening operation time and reducing procedure-associated complications.
An international multicenter study found that men and women with mild coronary artery disease and similar cardiovascular risk profiles share similar prognoses. The study analyzed data from 27,725 individuals in six countries and revealed that nonobstructive coronary artery disease conferred a similar adverse risk of death or heart atta...
A new study reports that individuals who underwent left gastric artery embolization experienced a 7.9% decrease in body weight, highlighting potential new avenue for obesity research. The procedure blocks the production of ghrelin, leading to decreased appetite and weight loss.
A study found that younger Hispanic and black women have a higher risk of in-hospital death after a heart attack compared to white men. Additionally, they are more likely to suffer from diabetes and have limited access to treatment options such as percutaneous coronary interventions or coronary artery bypass surgery.
A national study published in NEJM found that comprehensive medical therapy is as effective as renal stenting in preventing clinical events for patients with renal artery stenosis. The study, led by Rhode Island Hospital researchers, involved over 947 participants and followed them for up to seven years.
A clinical study found that exercise with GM-CSF boosts mobility in patients with peripheral artery disease. Participants who responded strongly to GM-CSF treatment showed significant improvements in maximum walking time.
A phase 2 study found that GM-CSF therapy did not improve treadmill walking time in patients with intermittent claudication, a common symptom of peripheral artery disease. The treatment may still warrant further investigation due to observed secondary outcomes.
A study of 3,398 participants found that higher coronary artery calcium (CAC) density was associated with a lower risk of heart disease and cardiovascular events. The researchers discovered that CAC volume was positively correlated with CHD and CVD risk, while CAC density was inversely related.
The HYBRID trial found that combining minimally invasive CABG with percutaneous coronary intervention is feasible and safe for patients with multi-vessel disease. At one year, 89.8% of the hybrid group was free from major adverse cardiac events.
The LEVANT 2 trial presents favorable 6-month data on drug-coated balloon angioplasty for treating femoropopliteal artery disease. Patients treated with a drug-coated balloon experienced higher primary patency rates (92.3%) compared to those receiving standard PTA alone.
A recent study confirms that medication and lifestyle changes are safer and more effective at preventing stroke than surgical stenting. The study found no significant benefit of surgery in reducing the risk of new strokes or death among patients with narrowed brain arteries.
A study published in Neurology found that elderly individuals with hardening of the arteries are more likely to have beta-amyloid plaques in the brain, a hallmark of Alzheimer's disease. The study also showed that increased arterial stiffness was associated with a higher risk of developing dementia.
A study published in JAMA found that coronary artery bypass graft (CABG) surgery provides slightly better health status and quality of life than procedures using drug-eluting stents for patients with diabetes and multiple arteries affected, but this difference disappears beyond 2 years.
Researchers found JAM-A facilitates immune cell recruitment to arteries, promoting plaque formation. Reducing JAM-A levels can slow lesion growth, but deleting the molecule from monocytes causes damage and increases plaques.
A researcher at UT Arlington is working on a new method using nanoparticles to recruit stem cells and build needed stents in failing blood vessels. The goal is to treat peripheral artery disease, which affects about 8 million Americans, with a less invasive approach that could save patients' lives.
A recent study published in The Lancet Diabetes and Endocrinology found that people with diabetes have a 30% lower risk of dying if they undergo coronary artery bypass surgery (CABG) rather than angioplasty and inserting a stent (PCI). This significant finding has public health implications due to the large difference in outcomes.
Researchers at The University of Manchester and medical institutes in Italy have identified a gene variant associated with vasospasm, a rare cause of heart attacks. This discovery could lead to the development of new drugs to treat this condition.
Researchers have discovered a compound that successfully blocks smooth muscle growth and promotes repair of the injured endothelium in stented arteries. This innovation has the potential to eliminate blood clots forming inside stents, reducing the risk of complications.
The AQUARIUS trial found that Aliskiren reduced major cardiovascular events and slowed atherosclerosis progression in patients with prehypertension. The study suggests these patients may benefit from more aggressive treatment of their blood pressure to reduce risk of death, stroke, and heart attack.
A recent trial by Cleveland Clinic found that the drug RVX-208 failed to improve coronary health in patients with low HDL cholesterol, contradicting previous hopes for an 'HDL-raising' treatment. The study used intravascular ultrasonography to assess plaque buildup and found no significant difference between RVX-208 and placebo.
A Facebook intervention led to increased HIV testing among high-risk men, with a peer-led group showing significant results. The study found that more participants requested an HIV testing kit after 12 weeks compared to the control group.