A new study reveals striking biological similarities between five major illnesses, including long Covid and PTSD, suggesting common underlying mechanisms. Chronic fatigue syndrome, rheumatoid arthritis, and multiple sclerosis may be driven by shared regulatory networks in immune and metabolic systems.
A new grant will allow researchers to develop a non-invasive magnetic resonance imaging (MRI) exam to detect early changes in tissue and improve diagnosis and treatment for lymphedema and lipedema. The SALT MRI approach tracks sodium, adipose tissue, and lymphatic fluids to better understand how they affect lymphatic function.
Researchers identify a specialized lymphatic network in the brain that enables cerebrospinal fluid drainage, which declines with age but can be restored through intranasal VEGF-C delivery. This discovery provides new insights into brain waste clearance and its link to neurodegenerative disorders.
Researchers found that overlapping yak urine and dung patches produce far less nitrous oxide than expected, contradicting the assumption of additive emissions. The study suggests a balance between two competing processes, preventing emissions from rising as much as expected.
Researchers at the University of Zurich have identified 10 biomarkers in saliva that can detect acute sleep deprivation. The study uses machine-learning methods to analyze metabolic changes in saliva, providing a new milestone for forensic research.
A study found that regularly assessing gastric residual volume in critically ill children being enterally fed significantly improved nutritional achievement at 72 hours. Not routine assessments every 6 hours had similar results, demonstrating noninferiority.
Researchers developed a nanowire device that selectively captures cancer-related extracellular vesicles from the blood serum of ovarian cancer patients. The technology uses high-performance zinc oxide nanowires and achieves efficient capture of cancer biomarkers with minimal physical burden on patients.
Researchers at Kyushu University developed a new mathematical model that simulates oxygen transport by red blood cells through tiny blood vessels and their delivery to surrounding tissues. The findings show that RBCs can naturally adjust the amount of oxygen released based on local requirements.
Researchers discovered that human urine contains essential nutrients for plants, including nitrogen, phosphorus, and potassium. The team developed a low-energy process to concentrate urine into a fertiliser-rich stream, reducing the burden on treatment plants.
The oXiris membrane addresses complex sepsis by integrating diffusion, convection, and adsorptive properties to remove inflammatory mediators. Early physiological improvements and potential benefits for cardiac surgery-associated acute kidney injury and severe COVID-19 have been reported in observational studies.
Researchers found that sleep-deprived individuals experience attentional failures coinciding with a flushing of CSF from the brain. During these lapses, physiological changes occur, including a flux of CSF out and then back in. The study suggests that the brain attempts to compensate for lost cleansing by initiating pulses of CSF flow.
A team of Virginia Tech researchers has discovered new insights into blood thinners and bone builders, heparin. The findings may lead to designing safer and more reliable heparin therapies. Heparin's molecular composition affects its ability to bind calcium, influencing its effectiveness in biomineralization and blood clotting.
A multicenter study found significant variation in how US hospitals define blood culture contamination, which can lead to inaccurate diagnoses and unnecessary treatments. The study suggests that standardizing definitions could improve the accuracy of diagnoses and optimize treatments.
Researchers at EHU developed a portable, cost-effective system for generating high-quality platelet-rich plasma (PRP), minimizing platelet activation and preserving therapeutic efficacy. The device uses gravity sedimentation and can extract up to 300 micro-liters of PRP from 1 milliliter of blood in just 40 minutes.
A new study has provided insights into how blood stains cotton fabrics, allowing investigators to gather additional information from forensic evidence. The researchers found that the number and spread of 'fingers' in the bloodstain correlate to the velocity of the blood spatter, with faster-moving blood leaving more prominent tendrils.
Researchers identified hundreds of molecular markers in saliva associated with systemic pathological processes beyond the oral cavity. These markers can reflect genetic heritability of diseases such as prostate cancer, coronary disease, and Type 2 diabetes.
Researchers developed a method using microRNA and messenger RNA to identify five common human body fluids at crime scenes. The combined mRNA and miRNA system showed significant advantages over previous methods, providing a scientific reference for RNA-based body fluid identifications.
Researchers at Sahmyook University repurposed meclofenamate to treat abnormal respiratory mucus, reducing mucin secretion and characteristics of respiratory mucus. This study offers an alternative solution for patients with respiratory diseases, saving time and costs compared to conventional drug development strategies.
Researchers developed predictive models using serum microRNAs to identify patients at risk of requiring early palliative care. The study used serum samples from 178 patients with various types of cancer and found that miRNA-based models had higher accuracy than clinical models in predicting referral to a palliative care unit.
A new study by NC State University found that total formulation impacts surface sanitizer efficacy against norovirus, with only alcohol-based products showing significant reduction. Additionally, paper towels used to clean up messes can be a source of cross-contamination.
Researchers at the University of British Columbia identified a new high-salt receptor, IR7c, in fruit flies that governs their ability to detect dangerously high concentrations of salt. This discovery provides insights into how animals sense and avoid excessive salt, which is essential for survival but can be toxic in high amounts.
Researchers developed a disposable electrochemical sensor using graphite-based molecularly imprinted polymers to detect theophylline levels. The sensor can identify low concentrations of theophylline (2.5 μg/mL) in whole blood within 3 seconds, enabling real-time monitoring and potential overdose prevention.
Researchers developed a single-use sensor strip that can detect cerebrospinal fluid (CSF) leaks, providing a rapid diagnostic tool for patients with brain and spinal cord injuries. The test uses antibodies specific to proteins found in human CSF, detecting leaks even when other substances are present.
A team of scientists at McGill University has invented a smart device for personalized skin care inspired by the male diving beetle. The device collects and monitors body fluids while sticking to the skin's surface, paving the way for more accurate diagnostics and treatment for skin diseases like acne.
A recent study found that hikers' performance during hot weather conditions was impaired, resulting in slower speeds and increased risk of heat-related illness. The researchers also discovered that most hikers did not bring enough fluid to compensate for sweat loss, with less fit participants being most negatively affected.
Researchers at MIT have developed a portable sensor that can accurately measure patients' hydration levels using nuclear magnetic resonance (NMR) relaxometry. The device has the potential to improve dialysis treatment for patients with kidney disease and could also benefit people with congestive heart failure, athletes, and elderly ind...
Aphid soldiers expel lipid-rich fluids to create a soft clot around the gall wound, which is swiftly hardened and melanin-darkened through phenoloxidase. This collective action amplifies an immune response for social defense, providing molecular clues to altruistic social defense mechanisms.
Researchers found no significant link between fluid infusion and brain injury in children with DKA, contrary to decades of clinical practice. The study provides more treatment flexibility for clinicians, but the authors continue to investigate potential causes of neurological damage.
A new study by Thomas Jefferson University found that women who received IV fluids at a higher rate during labor were less likely to need a cesarean section and had shorter labors. The study pooled data from seven small clinical trials involving over 1,200 women.
Research finds that cold and carbonation reduce thirst more effectively than room temperature, with astringency, sweetness, or mild acidification having no effect. This knowledge could help guide sensory approaches to improve hydration in elderly, soldiers, and athletes at risk for dehydration.
A study published in JAMA found that children with mild gastroenteritis and minimal dehydration experienced fewer treatment failures when offered half-strength apple juice followed by their preferred fluid choice compared to those who received electrolyte maintenance solution. The results suggest that diluted apple juice may be an appr...
A commentary published in Annals of Internal Medicine highlights two factors contributing to Ebola infection among healthcare workers: insufficient supply of personal protective equipment and inadequate donning/doffing procedures. To prevent transmission, the authors recommend a structured process for gear removal.
A new study found that bed bugs can survive freezing temperatures for a certain period, but prolonged exposure to cold can lead to their death. The researchers discovered that minimum exposure times of 80 hours at -16°C are required for 100% mortality.
Three winning teams received a $10,000 prize for their innovative projects addressing underserved populations and individuals with disabilities. The Personalized Monitoring of Enzyme Dynamics project focused on cancer treatment personalization, while the Microflora Refinement System tackled Clostridium difficile infections.
A new backboard cover, Board Armor, has been developed to reduce infection rates in patients and save valuable emergency response time. The synthetic material disposable cover prevents bodily fluids from contaminating the backboard and eliminates the need for cleaning between uses.
A study by McMaster University found that milk is more effective than water or sports drinks in rehydrating children after exercise. Milk provides high-quality protein, carbohydrates, calcium, and electrolytes, helping the body retain fluid better and supporting muscle development.
A study by Ben-Gurion University researchers found a higher incidence of insufficient amniotic fluid levels in the summer months. Pregnant women are advised to drink 10 glasses of water per day and avoid direct sun exposure to prevent fetal dehydration.
The National Institute of Standards and Technology (NIST) will develop a measurement assessment material for proteins, mimicking human plasma proteome complexity. This collaboration aims to evaluate existing proteomic technologies, develop new ones, and establish reliable measurement tools for cancer research.
A three-week study of ten obese volunteers with mild type 2 diabetes mellitus found that a very low-carbohydrate diet led to an average weight loss of 3.6 pounds, primarily due to reduced calorie intake rather than loss of body fluid or increased metabolism. The results suggest that carbohydrate restriction may stimulate excessive appe...
A new study by University at Buffalo exercise scientists reveals that dehydration can induce bronchospasm before exercise and exacerbate exercise-induced asthma. Researchers found that individuals with asthma are more sensitive to dehydration, leading to reduced respiratory capacity and increased difficulty during physical activity.