Articles tagged with Semen
A recent study found that a higher body fat percentage is linked to lower sperm counts and changes in male reproductive hormones. Men with high body fat percentages had lower semen volume, sperm concentration, and testosterone levels compared to those with normal body fat percentages.
A nationwide study found substantial regional differences in sperm quality, with men in northern Spain recording the strongest semen quality. Lifestyle habits were broadly similar across regions, suggesting environmental exposures may play a role in male reproductive health.
Researchers developed a new methodology to identify biomarkers for male infertility, enabling comprehensive analysis of lipids and metabolites. They found 955 potential metabolites and 473 lipids that could be present in sperm.
Research from the University of Colorado Anschutz suggests that stress experienced by a father before conception may alter small molecular signals in sperm, shaping early development and later physical growth. The study found that increased levels of let 7f 5p in fertilized eggs mimic the biological effects of paternal stress.
A human study found that prenatal and childhood exposure to persistent environmental chemicals may influence sperm chromosomal integrity decades later. Higher levels of PCBs and PFASs were associated with extra chromosomes in adulthood, increasing the risk of miscarriages and congenital birth defects.
Researchers have found a correlation between exposure to widely used pesticides and lower sperm quality in male rodents. The review of 21 studies indicates that neonicotinoid pesticides may disrupt hormones and damage testicular tissue, leading to potential harm to human reproductive health.
A review of 21 experimental studies suggests that exposure to neonicotinoid pesticides can lower sperm quality and disrupt hormones in males. The studies found that these insecticides, commonly used in farming, can be absorbed into soil, water, and plants, leading to potential harm to human reproductive health.
A recent study published in Oncoscience found that lifestyle choices and hormonal imbalances significantly impact male fertility in Indian men. The research discovered a strong association between poor habits such as tobacco and alcohol use, heat exposure, and body weight with lower semen quality and higher DNA damage.
Research shows that low phosphate levels in blood are associated with reduced sperm motility and poor semen quality. The findings suggest a potential link between phosphate and male fertility, highlighting the importance of understanding biological factors involved in reproductive health.
A large study of nearly 80,000 men found that those with better semen quality lived two to three years longer than those with poorer semen quality. The research suggests that poor semen quality may be an indicator of underlying health issues, and could potentially detect early signs of disease.
A study found that men infected with high-risk types of HPV could experience sperm death from oxidative stress, leading to impaired fertility. The researchers also discovered a weakened local immune response in the urogenital tract, which may contribute to these effects.
A recent study published in JAMA found that transgender women on hormone therapy have drastically lower PSA levels, which may lead to delayed diagnosis and treatment of prostate cancer. The researchers analyzed Veterans Health Administration records and recommended caution when interpreting PSA values in transgender women.
Researchers found SARS-CoV-2 in male reproductive cells even when PCR testing failed, revealing a prolonged infection period of up to 90 days. The virus can remain in sperm for 110 days, reducing semen quality and raising concerns for natural conception and assisted reproduction.
The project aims to overcome limitations of conventional semen analyses by examining mitochondrial DNA levels in sperm as a novel biomarker of sperm fitness. Researchers will evaluate relationships between mtDNA biomarkers and male reproductive health using large study samples.
Men with low sperm count or none have a higher risk of developing cancer, including at younger ages, compared to fertile men. Families of azoospermic men have a significantly increased risk of five cancers, while families of oligozoospermic men have a higher risk of colon, bone and joint, and testicular cancers.
Researchers at Salk Institute find a new method to interrupt sperm production using an HDAC inhibitor, which blocks fertility without affecting libido. The treatment's reversibility is attributed to its ability to modulate gene expression downstream of retinoic acid.
In a groundbreaking study, researchers observed that serotine bats mate without penetration, using their oversized penises like an extra arm to engage in contact mating. The bats' penises are seven times longer and wider than their partners' vaginas, making penetration impossible.
A large cross-sectional study of over 2,800 young men in Switzerland found an association between mobile phone use and lower sperm concentration. While no link was discovered to poor sperm motility or morphology, the results suggest that reduced semen quality may be linked to increased mobile phone usage.
A new specimen collection system has been developed to enhance assisted reproductive technologies by providing a simple one-step method for selecting high-quality sperm for ICSI. The system, known as NovaSort, uses a barrier mesh to isolate mobile sperm without damaging their DNA.
New study finds that men who suffered from mild COVID-19 have lower sperm concentrations and motility even three months after recovery. The researchers believe that the virus may cause permanent damage to male fertility, leading to long-term decline in semen quality.
Researchers developed a new approach to evaluate HIV infection through the entire male genital tract, showing that productive HIV infection occurs in all organs of the male genital tract. Antiretroviral treatment can suppress HIV production and prevent penile HIV infection by using pre-exposure prophylaxis with an antiviral drug.
Researchers at São Paulo State University developed a new technique for analyzing male fertility potential using flow cytometry, which can detect and analyze chemical and physical characteristics of human sperm simultaneously. This technique has the potential to enhance the accuracy of fertility prediction and treatment.
Researchers identified over 1,000 genes with age-related methylation changes in human sperm. These changes are associated with increased offspring disease susceptibility for neurodevelopmental disorders. The study found no correlation between paternal BMI or semen quality and age-related methylation changes.
Scientists have detected monkeypox virus in the testes of macaques during acute infection and found preliminary evidence of persistent infection in two convalescent animals. The study highlights the potential for sexual transmission of the virus in humans, particularly in convalescent male patients.
A recent study published in ACS Omega analyzed protein levels in semen of men who recovered from COVID-19 and found significant reductions in sperm count, motility, and normally shaped sperm. The researchers also detected changes in fertility-related proteins such as semenogelin 1 and prosaposin.
A new test, RHEOLEX, can quickly detect breeding bull fertility levels using a simple, home pregnancy test-like device. The test mimics the biological process of rheotaxis, in which sperm swim upstream in the reproductive tract, to quantify the sperm's ability.
Scientists discovered two new targets, EPPIN domains, to block sperm motility, a complex process that allows sperm to reach the egg. The study demonstrates the feasibility of using mice as models for in vivo trials, simplifying preclinical studies and paving the way for novel male contraceptives.
Researchers at Washington State University developed a new form of non-hormonal, over-the-counter contraception by blocking prostate-specific-antigen in human ejaculate samples. This prevents semen from liquefying, trapping most sperm and allowing for effective fertilization prevention.
Researchers found that men exposed to endocrine disruptors in utero are twice as likely to have low semen volume and sperm count. Exposure to pesticides, phthalates, and heavy metals is associated with poorer sperm quality.
A study from Keck Medicine of USC found that a mail-in sperm testing kit can accurately analyze semen up to 52 hours after collection, surpassing the current one-hour test. This innovation allows men to provide specimens from home, improving flexibility and accessibility for fertility evaluations.
Researchers investigated semen tests in men infected with SARS-CoV-2, finding notable differences in test results and clinical features. The study revealed distinct patterns of sperm abnormalities and hormone imbalances among these patients.
Researchers analyzed data from Chinese men who recently had COVID-19 and found no evidence of the virus in semen or testes. However, the study's limitations mean it cannot fully rule out the possibility of sexual transmission.
The clitoris activates changes in the reproductive tract to create readiness for sperm to fertilize an egg. Removal of the clitoris may lead to both sexual and reproductive disabilities.
Researchers have discovered that certain molecules in semen, known as miRNAs, may serve as non-invasive biomarkers for prostate cancer. The study found that these molecules can provide reliable information to help diagnose and predict the progression of the disease.
Scientists found that frequent and sustained semen exposure can change the characteristics of immune cells targeted by HIV-1, reducing susceptibility to future infections. While it does not block infection, repeated semen exposure may promote host resistance, raising new hypotheses for HIV vaccine studies and prevention strategies.
Researchers identified a potent pheromone called spermine in the semen of sea lampreys that attracts only ovulatory female sea lampreys. The discovery may reveal a new mechanism for male animals to recruit mates through chemical cues in semen, potentially with implications for conservation and management of sea lamprey populations.
A study of almost 5000 IVF/ICSI cycles found that paternal age over 51 years significantly affects the chance of success, while miscarriage rates remain unchanged. Men are advised to not delay fatherhood due to declining natural fertility with increasing age.
A large population study has found that paternal smoking is associated with lower total sperm counts and concentrations in adult sons, regardless of maternal smoking. The study, which analyzed data from over 778 young men, found an 8-9% decline in sperm count and concentration among sons of fathers who smoked daily.
A large-scale study found that long-term cryopreservation of semen does not affect pregnancy and live birth rates in women using donor sperm. The study analyzed 119,558 semen samples stored for up to 15 years and found similar success rates in IVF and donor insemination, despite a decline in frozen sperm survival rate over time.
The first nationwide study on semen quality in Switzerland found that 38% of young men have semen parameter values above the WHO norms. Poor semen quality is associated with an increased risk of testicular cancer and infertility, with 25% of men having less than 40% motile spermatozoa.
Scientists at University of Sydney have successfully used 50-year-old ram sperm to impregnate 34 Merino ewes, demonstrating the viability of long-term frozen storage. The resulting live birth rate was comparable to that of recently frozen semen.
A new study published in Human Reproduction found that men who have smoked marijuana at some point in their life had significantly higher concentrations of sperm compared to men who have never smoked. The study also found no significant difference in sperm concentrations between current and former marijuana smokers.
A unique switching valve in the sperm-storage organ of Neotrogla insects allows females to receive two capsules of semen at once, leading to fierce competition over mating and eventual evolution of a female penis. The discovery, published in eLife, has potential applications in biomimetics and nanotechnology.
A recent study of 744 infertile men found that 15.4% had undiagnosed prediabetes, with factors including older age and high follicle stimulating hormone levels linked to the condition. The study suggests that infertility in men may be associated with impaired glucose metabolism.
A recent study published in Molecular and Cellular Proteomics found that men should have frequent sex around the time of ovulation to improve their chances of conception. The research suggests that longer periods of abstinence can cause DNA damage in sperm, negatively impacting fertility rates.
Men who wear loose-fitting boxers have significantly higher sperm concentrations and total sperm counts compared to those who don't. Researchers found a potential compensatory mechanism where decreased sperm production triggers hormone production boosts to stimulate gonad activity.
A new study published in Human Reproduction journal found that men who wear boxer shorts have higher sperm concentrations than those who wear tighter fitting underwear. The researchers also discovered a link between the type of underwear and lower levels of follicle-stimulating hormone (FSH), which stimulates sperm production.
A randomized trial found that a 14-week nut-rich diet significantly improved sperm quality, including increased count, vitality, and motility. The study also showed a reduction in sperm DNA fragmentation, associated with better male fertility.
A study of 5,177 male partners of infertile couples found that low sperm counts are associated with metabolic alterations, cardiovascular risk, and low bone mass. Men with low sperm counts were more likely to have a bigger waistline, higher blood pressure, and lower HDL cholesterol.
Researchers detected yellow fever virus in urine and semen samples from a patient who survived the disease almost a month after infection. The discovery suggests the virus may be contagious for a period longer than previously thought, potentially allowing asymptomatic individuals to transmit the disease.
A study of 796 male volunteers found that shorter or longer sleep durations were associated with lower High DNA Stainability in sperm. Volunteers sleeping 6.5 hours or less had 30% lower DNA stainability compared to those sleeping 7-7.5 hours.
Significant declines in sperm counts among men in Western countries are alarming, with a 52% fall between 1973 and 2011. The research highlights the need for further investigation into the causes of these trends, which may be linked to exposure to endocrine-disrupting chemicals.
A meta-analysis of studies found frequent sperm aberrations and lower fertility rates among men after undergoing Roux-en-Y gastric bypass procedures. Researchers identified elevated estrogen hormone levels and deficient vitamin D as potential factors contributing to semen abnormalities and reduced fertility.
Researchers found that populations of males who have sex with males can form an outbreak-sustaining core, while heterosexual populations experience smaller outbreaks. This raises concerns about silent, sustained outbreaks in the community, particularly among men who are least likely to get tested for Zika.
Researchers at the University of North Carolina Health Care found that Ebola virus RNA can persist in the semen of survivors for more than two years after infection. This persistence has important implications for transmission and may require an update to World Health Organization guidelines.
Researchers discovered that semen amyloids help dispose of excess and defective sperm, facilitating immune cell removal and quality control. This process may favor the survival of fittest sperm and contribute to successful reproduction.
A reliable clinical assay can detect the Zika virus from semen samples with a limit of detection of 5 viral copies per mL of semen. This assay has been validated through experiments with 100 semen samples spiked with recombinant Accuplex ZIKV and tested for other viruses.
A Washington State University researcher has found that the uterus in female mice contains enzymes that break down semen, making it less gel-like and easier to swim. The study highlights an underappreciated complication in semen liquefaction and could lead to diagnostic tools for unexplained infertility.
A new smartphone-based device can analyze sperm concentration and motility with high accuracy, making it a game-changer for fertility care. The device has been tested with 350 clinical semen specimens and shows promise in detecting abnormal semen samples.
Scientists have developed a low-cost smartphone attachment for at-home fertility testing, enabling men to monitor their semen quality. The Fertilex platform can detect abnormal semen samples with over 95% accuracy, providing a reliable resource for the millions affected by male infertility.