Articles tagged with Menopause
Higher levels of perfluorocarbons associated with increased odds of experiencing menopause in women between 42 and 64 years old. Women with high PFCs also had lower estradiol concentrations.
The European Menopause and Andropause Society publishes two important position statements covering common management problems in post-reproductive health, including hormone therapy options for Cardiovascular disease and Osteoporosis. The statements provide summary recommendations for clinicians to manage menopause-related symptoms.
A large cohort study found that hormone therapy started at menopause increases breast cancer risk, particularly among women who start therapy before or soon after menopause. The study's results support previous findings and provide new insights into the relationship between timing of hormone therapy and breast cancer risk.
Research suggests that smoking before menopause may be associated with an increased risk of developing breast cancer. Women who smoked more or longer had a higher risk of breast cancer, while passive smoking was not linked to an increased risk.
Researchers at UNC Chapel Hill are conducting a clinical trial to determine if estrogen replacement therapy can help prevent depression and cardiovascular illness in women between 45-55. The study, funded by the NIH, aims to identify which women will benefit from estradiol treatment during perimenopause.
A genetic test predicting early menopause risk could help UK women in their 30s plan families. Researchers identified four genes associated with early menopause and found they combined to have a larger impact on the condition.
The International Menopause Society launches new treatment recommendations for postmenopausal vaginal atrophy, a condition affecting up to half of women after menopause. The guidelines aim to improve awareness and understanding of VA among women, who often live with the condition unnecessarily due to fear of hormone replacement therapy.
A new soy-based natural S-equol supplement reduced the frequency of moderate to severe hot flashes and muscle and joint pain in postmenopausal U.S. women. The study found that lower doses of Natural S-equol significantly improved symptoms, with no clinically significant adverse effects.
The European Menopause and Andropause Society (EMAS) has published four position statements on common management problems in the post-reproductive health of women. The statements cover the management of menopause in the context of obesity, epilepsy, endometriosis, and premature ovarian failure.
A new study from Virginia Commonwealth University finds that antidepressant desvenlafaxine, known as Pristiq, effectively treats major depression in women during perimenopause and menopause. The medication showed significant improvement in symptoms, with response rates of 58.6% for those taking Pristiq compared to 38.2% on placebo.
Research suggests that SE5-OH containing Natural S-equol can help alleviate hot flushes and other menopausal symptoms. Additionally, studies have found that soy-based diets may help prevent bone loss in postmenopausal women.
A new study from the University of Sheffield found that social and psychological factors have a bigger impact on women's sex lives during menopause than previously thought. The research suggests that individual experiences vary greatly, with external factors like relationships and care-giving playing a significant role.
A study on killer whales and pilot whales reveals a common link with humans in the evolution of menopause. Females in these species become genetically related to those they live with as they get older, leading to a 'grandmother' role that helps ensure group survival.
A new study by Dr. Fahimeh Ramezani Tehrani predicts the age when women will hit menopause using a simple blood test. The researchers found that the accuracy of the test is high, with an average difference between predicted and actual ages of just a third of a year.
Women who experience early menopause are more than twice as likely to have a heart attack, stroke, or other cardiovascular disease event later in life. The study also found that early menopause remained a risk factor even after controlling for hormone replacement therapy and major cardiovascular risk factors.
A study identified nine key symptoms associated with late-onset hypogonadism, including decreased sexual function and energy levels. The researchers found that testosterone treatment may only be useful in a small number of cases, highlighting the need for clear diagnosis criteria.
SE5-OH containing natural S-equol significantly reduced frequency of hot flushes in postmenopausal women. The compound had no effect on reproductive hormones E2 and FSH, suggesting its potential as a critical component in reducing menopausal symptoms.
Researchers found that increased follicle-stimulating hormone (FSH) levels correspond to lower bone density in postmenopausal women. FSH stimulates the production of cytokines, such as interleukin-1 beta, which activate osteoclasts and lead to bone loss.
New analyses confirm that combination hormone therapy increases the risk of heart disease in healthy postmenopausal women, particularly those who begin therapy within 10 years of menopause. The risk is more pronounced among women who start therapy 10 years or more after menopause.
A large-scale study found that estrogen-only hormone replacement therapy (HRT) may increase the risk of developing asthma after menopause. Women who used estrogen-only HRT were 21% more likely to develop asthma than those who never used HRT, with a significant increased risk among non-smokers and those with previous allergies.
The International Menopause Society consensus statement emphasizes the importance of raising awareness about cardiovascular disease risks in postmenopausal women. The statement also concludes that hormone replacement therapy (HRT) is generally safe and may have cardioprotective effects, particularly for younger women.
A study of postmenopausal women found that the risk of hip fractures steeply rises with age, being seven times higher in 70-74 year olds than in 50-54 year olds. The study also discovered a slightly increased risk for early menopause before age 45.
A combination of estrogen and a selective estrogen receptor modulator (SERM) may relieve menopause symptoms and lower breast cancer risk without the progestin side effects. Researchers treated breast and endometrial cell lines with the hormone mix, finding that it blocked cell growth and prevented proliferation.
A clinical trial found that a supplement containing SE5-OH and Natural S-equol improved menopausal symptoms, including reducing hot flashes by 58.7 percent, in postmenopausal Japanese women. The study also showed positive improvements in other menopause symptoms.
A new study published in the International Journal of Cancer found that women who experienced non-natural menopause are at almost twice the risk of developing lung cancer compared to women who experienced natural menopause. The increased risk was particularly observed among women who had both their ovaries surgically removed.
Women experience cognitive decline during the menopause transition, with verbal memory and processing speed affected. However, these declines are temporary and resolve once women enter postmenopause, suggesting that estrogen or progesterone may have a beneficial impact on brain function before menopause.
A genome-wide association study identified 20 single nucleotide polymorphisms related to an earlier menopause, which could affect fertility in women. The study suggests that understanding these genetic variants may help improve fertility treatment for women with infertility issues.
A new survey reveals that post-menopausal women are reluctant to discuss vaginal dryness and pain due to embarrassment, affecting up to 47% who prefer discussing symptoms with a female physician. Despite this, 67% of those treated experience improvements in quality of life and sexual activity.
Researchers have identified two chromosomal regions associated with the age at which females experience their first menstrual period (menarche) and the onset of natural menopause. The study may help shed light on the prevention of breast and endometrial cancer, osteoporosis, and cardiovascular disease.
A systematic review of 106 studies found that acupuncture is not effective in reducing the frequency and severity of hot flushes during menopause. While one study suggested favorable effects of acupuncture on symptom severity, the overall evidence does not support its use as a treatment option.
A new study published in Menopause: The Journal of the North American Menopause Society found that transdermal estrogen delivery may not increase the risk of blood clots in postmenopausal women, unlike oral delivery. The study suggests that transdermal HT delivery may be a safer alternative for some women.
A study found that women with a history of breast cancer who use synthetic steroid tibolone are at a 40% increased risk of recurrence. The drug was linked to distant metastases, which are often fatal. Tibolone should not be prescribed to breast cancer patients.
Primary ovarian insufficiency is a menopause-like condition affecting girls and young women, characterized by loss of menstrual periods, infertility, and hot flashes. A comprehensive plan provides recommendations for diagnosis and treatment, including hormone replacement therapy and counseling.
A study by Université Laval researchers found that omega-3 supplements significantly improved menopause-related mental health problems, including depression and hot flashes, in women aged 40 to 55. However, the effectiveness of omega-3s for more severe depressive symptoms was limited.
A new study has found a possible connection between shorter menopause and faster progression of atherosclerosis, which can lead to heart disease. Women who transitioned more quickly through menopause were at higher risk for a higher rate of progression of preclinical atherosclerosis.
Chronic kidney disease exacts a significant toll on women's sexuality and gynecologic health, with hormonal changes affecting body functions. Experts will explore the impact of CKD on women's sexual life cycle, fertility, and pregnancy from adolescence through menopause.
Researchers at the University of Michigan found that declines in anti-Mullerian hormone (AMH) and inhibin B concentrations predict the time to menopause, while changes in follicle-stimulating hormone (FSH) stages identify different reproductive periods. This information can help women understand their biological clock and fertility.
The University of Nottingham is conducting a study to understand women's experiences working through menopause, with the goal of providing useful information for women, employers, and doctors. The research aims to address the significant gap in understanding the effects of menopause on women's working life.
A study published in Sleep found that postmenopausal women slept longer than premenopausal women, with deeper sleep and increased total sleep time. However, the rate of change in sex hormones during menopause was also associated with poor subjective sleep quality.
A recent observational study published in the Journal of the National Cancer Institute suggests that hormone therapy may be safe for postmenopausal women with BRCA mutations. The study found a 42% relative reduction in breast cancer risk among women who used hormone therapy, although further research is needed to confirm these findings.
A study found that estrogen therapy reduced the risk of fractures after menopause, particularly in women aged 50-64 years. The use of post-menopausal hormone replacement therapy increased greatly during this period and was estimated to cause nearly half of the decline in fracture rates among women.
A large trial found significant improvements in quality of life, sleep and joint pain for post-menopausal women on hormone replacement therapy. Researchers also noted improved sexuality among participants.
Researchers at the University of Missouri discovered significant changes in the brain's vascular system after menopause. The study advises extreme caution when using estrogen-based hormone therapies due to potential complications and adverse effects on vascular health.
A new animal study suggests that estrogen treatment is not toxic per se, but its effects on the brain depend on an individual's reproductive age. In rats, estrogen therapy reduced brain damage when given before menopause, but increased it after, highlighting a narrow window of time for neuroprotective benefits.
A recent study found that women with delayed sleep phase syndrome are more likely to experience irregular menstrual cycles and premenstrual symptoms. The research suggests that circadian misalignment may play a role in these menstrual irregularities. Further investigation is needed to confirm these findings.
Global menopause experts conclude that HRT is safe and beneficial for healthy women in the early postmenopausal period. The Zürich Summit reviews evidence on the safety, risks, and benefits of HRT, finding no increased risk of chronic heart disease or breast cancer in this group. HRT also maintains bone health and may delay cognitive d...
Treatment advances for fibroids and endometriosis aim to preserve reproductive potential while treating these conditions. Novel conservative approaches, including medical treatments and non-invasive procedures, are now available, offering women more choices during menopause.
A new study published in the Journal of Clinical Endocrinology & Metabolism reveals that anti-Müllerian hormone (AMH) levels can predict a woman's reproductive age and onset of menopause. AMH levels reflect the number of small follicles present in a woman's ovaries, enabling monthly ovulations.
A study of 121,700 women found that postmenopausal hormone therapy is associated with a higher risk of stroke, even in younger women taking hormones near menopause. The risk was strongest for those taking larger doses and longer durations of hormone therapy.
Researchers found that hormone therapy started around menopause onset may have similar benefits as those without risk factors for heart disease. The study suggests that current guidelines may need to be revised for younger women taking hormone therapy.
A study of 110 women entering menopause found that sleep disruption was the most severe symptom reported, affecting 95% of participants. Despite changes in frequency of other symptoms as they progressed through the menopause, sleep difficulties remained constant, contradicting earlier research.
Menopause is thought to be an evolutionary adaptation that helps minimize reproductive competition between females in the same family unit. The researchers propose that older women should cease breeding when younger women start to breed, explaining the observed timing of reproductive cessation in humans.
Research highlights the importance of social support and accurate information for menopausal women in rural areas, who often struggle to access reliable healthcare. Trained nurses and female community leaders can play a key role in building local support networks and providing comprehensive care.
A study of wild chimpanzees found they do not experience menopause, unlike humans and most other primates. In contrast to human females with several decades of post-reproductive life, chimpanzee reproductive declines occur in tandem with overall mortality.
A study of 10 postmenopausal women found that lower estradiol levels and higher luteinizing hormone (LH) levels correlated with poor sleep quality. Higher body temperature before and during sleep also contributed to poorer sleep efficiency and increased LH levels.
A study published by the American Academy of Neurology found that hormone therapy taken in early post-menopause has no effect on women's memory, but may lead to increased sexual interest. The research involved 180 women who underwent tests on cognitive function, emotional status, and sleep.
Only 29% of women surveyed knew about the landmark hormone therapy study two years after its announcement, highlighting a flawed mechanism for communicating crucial health information to patients. The study found that discussions with physicians were key to retaining this knowledge, but many women reported never having such conversations.
Researchers at Stanford University and UCSB found that older men's fertility contributes to human longevity by postponing the date with death. This effect has a spillover impact on women due to gene passing, benefiting the population as a whole.
Research suggests that removing ovaries before menopause may lead to increased risks of cognitive decline and movement disorders such as Parkinson's disease. Women who underwent surgery at a younger age were found to be more likely to develop dementia and Parkinsonism.
Researchers show that traditional mating patterns make men essential to understanding the 'wall of death,' a puzzle in human lifespan. Men's reproductive patterns differ from women's, with earlier and more gradual decline after female menopause.