Articles tagged with Digital Publishing
Researchers found that NSD2 helps maintain MM cell identity by reorganizing DNA and influencing gene activity. This discovery could shape future treatment approaches for patients with t(4;14) myeloma.
Researchers discovered senolytics can target Alzheimer's disease-associated brain enzymes AChE and BChE without affecting healthy ones. This selective approach may lead to safer treatments that improve memory and reduce inflammation in older adults.
A new study reveals Japanese citizens broadly susceptible to illiberal narratives, posing risks to Japan's political discourse. The research found that illiberal narratives exert a stronger influence than mainstream democratic messaging.
The MIT Press has funded the open publication of 320 books through its Direct to Open framework, which shifts from market-based purchase models to collaborative library-supported open access. This approach has shown significant usage and citation increases for Humanities and STEAM books, with a notable impact on global readership.
The SpongeBoost project visualizes sponge functions in wetlands using a comic book, simplifying complex concepts for experts and non-experts. The first edition of the comic book is available online, promoting nature-based solutions to enhance landscape resilience.
A study using NHANES data found that inflammation, rather than diet and exercise, has the strongest association with telomere shortening. Managing chronic inflammation may be key to preserving telomere length and promoting healthy aging.
The University of Würzburg's Thesaurus Linguarum Hethaeorum Digitalis (TLHdig) offers online access to over 400,000 transliterated lines of cuneiform texts, expanding researchers' ability to study ancient Near Eastern languages.
In 2024, MDPI published 238,000 peer-reviewed open-access articles, tripling its research integrity team size. The publisher expanded its global workforce to 6,650 staff across 21 offices, publishing more than 25 million downloads of fully open-access research.
A new study found that treating aged mice with montelukast improved retinal health by reducing inflammation and boosting proteasome activity. This approach may offer a promising new way to slow age-related vision loss and protect eye health in older adults.
A new study presents a proof-of-concept leptomeningeal neural organoid (LMNO) fusion model to study meninges-brain signaling. The co-culture system of neural organoids fused with fetal leptomeninges from mice demonstrates stability and interface characteristics.
A new editorial highlights a growing concern in cancer care: radiotherapy may leave behind residual disease that can lead to worse long-term outcomes. Studies have shown that patients with residual disease are more likely to experience cancer recurrence and shorter survival, emphasizing the need for regular biopsy-based tests.
The company will use AI translation tools to publish books in multiple languages, making them accessible to a broader audience. This initiative aims to promote better understanding between cultures and accelerate awareness of knowledge required to meet today's challenges.
The WIN Consortium is transforming cancer care through personalized medicine, leveraging AI, molecular profiling, and clinical trials. The organization's innovations, including N-of-1 clinical trials and WINTHER and WINGPO trials, are helping clinicians make more precise treatment decisions and improving outcomes for cancer patients.
Breast cancer survivors experience accelerated aging due to detrimental effects of BC and its treatments, particularly systemic therapies. The study highlights the need for ongoing monitoring and potential strategies to slow down aging in cancer survivors.
A research team at Kumamoto University developed a deep learning-based method for analyzing the cytoskeleton more accurately and efficiently than ever before. This technique enabled more reliable measurements of cytoskeleton density, which is critical for understanding cellular structure and function.
Impact Journals is proud to exhibit at the AACR Annual Meeting 2025, featuring its esteemed journals Aging-US, Oncotarget, Oncoscience, and Genes & Cancer. The meeting highlights significant advancements in cancer research, aligning with Impact Journals' mission to disseminate impactful scientific research.
A new study investigates how AI can empower communities to actively participate in scientific research, addressing critical ethical considerations. The research aims to advance health equity and public health outcomes by enhancing citizen science with AI technologies such as conversational AI, generative AI, and predictive analytics.
A cross-sectional survey revealed high costs, inadequate training, and poor financing as major challenges to gastrointestinal endoscopy practice in Nigeria. Locally developed innovations have eased the practice, preventing it from collapsing.
A recent study found that 45.9% of ChatGPT-generated feedback was rejected by second-language learners, with content-focused feedback facing higher rejection rates. The researchers identified four key factors driving rejection: misalignment with goals or external standards, and the subjective nature of content-related suggestions.
The Biodiversity Data Journal has launched its own data portal on GBIF, providing seamless access to nearly 300,000 biological organism occurrences. The portal also offers direct access to over 800 datasets and 1,000 citations of associated journal articles.
This theme issue explores digital health solutions to address social isolation, health literacy, and cultural influences on aging health. Contributors are encouraged to submit their work by September 30, 2025.
A Chinese research team has created a single-step femtosecond laser 4D printing technology that enables rapid and precise micro-scale deformation of smart hydrogels. The innovation mimics the hierarchical structure of butterfly wings, promising applications in flexible electronics and minimally invasive medicine.
Core-shell nanoparticles offer effective drug encapsulation, shielding from degradation, and controlled release. This innovation enables targeted drug delivery, improving treatment outcomes and reducing side effects. The versatility of these nanoparticles allows for tailored materials to suit different therapeutic needs.
Researchers found that GenAI feedback offers timely and personalized feedback, educational benefits as an essay editor and tutor, and social benefits as a supportive environment. However, challenges include limited AI skills, dependency risk, and emotional understanding limitations.
The article discusses the need for bioanalytical assays to measure immune responses to oligonucleotide therapeutic drugs, especially when they include carriers or conjugates. Highly specific antibodies may enhance the development and production of ONTs, expanding studies on their safety and efficacy.
A comprehensive analysis of Bluesky reveals its structure, polarization, and political leanings. The platform's users, particularly those from X (formerly Twitter), exhibit left-leaning tendencies, as evident in the majority of shared links and content. The study also highlights how Bluesky diverges on the Israel-Palestine conflict topic.
Researchers from Yale University and Altos Labs have identified age-invariant genes that stay the same across all tissues during aging. These genes are linked to essential cellular functions, challenging the common belief that gene dysregulation drives aging.
A new test called EpiAgePublic estimates biological age using only three DNA sites in the ELOVL2 gene, simplifying traditional methods while maintaining accuracy. The study found that EpiAgePublic accurately tracks aging patterns and can identify factors accelerating the aging process.
A consensus statement by the Chinese College of Interventionalists promotes CBCT use in liver malignancy therapies, addressing limitations and challenges. The integration of artificial intelligence and technological innovations are expected to refine CBCT's efficacy and safety.
Researchers have discovered several novel downstream p53 targets that could lead to improved cancer therapies. The study highlights the critical role of p53 in preventing cancer and identifies two new genes, ALDH3A1 and NECTIN4, as potential targets for cancer treatment.
A study found that pro-inflammatory molecules contribute to benign prostatic hyperplasia (BPH) in aging men, especially those with metabolic syndrome. Men with BPH had higher levels of pro-inflammatory markers and lower anti-inflammatory substances, suggesting a link between inflammation and prostate conditions.
A synthetic retinoic acid-inducible gene I (RIG-I) agonist RNA has been shown to induce innate immune signaling and death of hepatocellular carcinoma cells in vitro. The addition of recombinant interferon-b potentiated this cell death, suggesting a potential new mechanism for treating patients with liver cancer.
A rare case of adenomyosis in an 81-year-old postmenopausal woman closely resembles invasive endometrial cancer, emphasizing the challenges of diagnosing this condition. Further studies are needed to refine diagnostic protocols and determine risk factors for postmenopausal patients.
ABT-263 eliminates harmful aging cells in the gut, reducing inflammation and lowering cancer risk in a mouse model of GI cancer. The study suggests that removing senescent cells could help prevent radiation-related GI cancer, highlighting the potential of senolytic drugs as a preventive treatment.
Researchers found that a combination of Panitumumab and low-dose Capecitabine is an effective and well-tolerated maintenance regimen for patients with wild-type KRAS metastatic colorectal cancer. The treatment delayed disease progression while managing side effects, improving patients' quality of life.
Osteosarcoma cells often have extra copies of the SETDB1 gene, making the cancer more aggressive and harder to treat. Blocking SETDB1 may help the immune system recognize and attack osteosarcoma cells, offering a promising new way to treat this type of bone cancer.
A rare case report highlights the association between systemic mastocytosis and severe osteoporosis in a young adult patient, emphasizing the importance of early diagnosis and consideration of SM as an underlying cause. The study aims to raise awareness about this underrecognized condition and its potential impact on bone health.
The expanded partnership makes it easier for researchers to discover OA funding opportunities through Taylor & Francis OA agreements. Researchers can now explore an additional 178 titles, including unique journal profiles and enhanced discoverability on ResearchGate.
A study found that DNA methylation clocks used in forensic science and epigenetics are less reliable when applied to non-blood tissues, such as lungs, colon, and kidneys. The researchers suggest that organ-specific epigenetic clocks may be needed to improve biological age prediction.
Researchers at UMH develop a mathematical model with three allocation rules to improve revenue sharing on streaming platforms. The model aims to address the issue of opaque revenue distribution, prioritizing creators' needs and promoting fairness.
A new analysis found a 50% higher rate of hate speech on X after Elon Musk purchased the platform, with bot accounts remaining unchanged. The study contradicts previous claims of reduced hate speech and bot activity on X.
A recent study found that cold temperatures allow the bird pink eye pathogen to survive on bird feeders for up to seven days, causing more severe disease in birds compared to warmer temperatures. Regular cleaning of feeder surfaces with bleach can help mitigate the spread of the disease.
A new case report reveals a rare and aggressive form of leukemia developing from donor cells nine years after a stem cell transplant. The disease, driven by genetic mutations in key genes, progresses despite intensive treatment and ultimately proves fatal.
A new genetic mutation, RUFY1-RET fusion, was discovered in a patient with stage IV CD-74-ROS1 fusion NSCLC who developed resistance to lorlatinib. The finding highlights the importance of ongoing genetic testing to guide therapy decisions.
A large study found pregnant women with cervical cancer face higher health risks during pregnancy and childbirth, including premature birth and cesarean sections. However, the babies' health is largely unaffected, with no significant differences in birth defects or stillbirths.
A study found clear differences in brain health between Hispanic and non-Hispanic White older adults, with Hispanic participants scoring lower on tests of memory, attention, and problem-solving despite similar mental health. Researchers emphasize the importance of considering social, economic, and cultural factors when developing progr...
Researchers discovered that a topical ABT-263 treatment effectively reduces aged skin senescence markers, priming the skin for improved subsequent wound healing. The treatment also triggered inflammation, which surprisingly helped the healing process by 'waking up' the skin's repair systems.
Dr. Gunther Eysenbach is stepping down as CEO of JMIR Publications to focus on innovation in academic publishing and AI-driven solutions. Sean Jeong takes over with a proven track record in digital transformation, agile delivery, and program execution.
A new algorithm proposes measuring quadriceps muscle mass for more accurate sarcopenia diagnosis, potentially leading to earlier detection and better treatment options. Ultrasound imaging is recommended as a cost-effective and practical solution for diagnosing sarcopenia in clinical settings.
A recent study evaluating NewsGuard's media reliability rating service found no evidence of bias against conservative news outlets. The analysis of over 11,000 sources in nine countries revealed stable trustworthiness scores since 2022, with the US receiving lower ratings due to hyper-partisan sources lacking editorial practices.
Researchers found a genetic change, pR552*, that could give the RB1 gene a new function leading to cancer growth. This challenges the common belief that both copies of the RB1 gene must be damaged for cancer to develop.
Aging cats with chronic kidney disease (CKD) have lower levels of key kidney transporter genes, leading to impaired waste removal. Monitoring these transporters and toxin buildup may help detect CKD early and improve treatment options.
Researchers tracked cfDNA levels before, during, and after colorectal cancer surgery, revealing significant increases associated with age, comorbidities, and surgical manipulation. The study suggests that cfDNA could serve as a non-invasive biomarker to monitor patient outcomes and evaluate surgical effectiveness.
Researchers discovered that removing arginase-II gene can slow down muscle aging in mice, leading to improved muscle health and reduced inflammation. This finding suggests targeting the Arg-II gene could help maintain muscle strength and mobility in older adults.
The new eReader combines full range of features, including personalization, powerful search and offline access, to provide a seamless experience. Developed in conjunction with Taylor & Francis' accessibility team, it meets European Accessibility Act requirements and supports ePub3 format.
A new study published in Oncotarget discovered an anti-correlation between PD-1 and KLRG1 expression in human tumor infiltrating CD8 T cells. This finding suggests the potential for combination therapy to enhance cancer treatment by targeting both markers simultaneously, which could lead to more significant and long-lasting benefits.
The Global Conference on Gerophysics aims to bridge statistical mechanics, complex systems theory, and dynamical modeling with biological mechanisms of aging. The conference will bring together leading scientists to promote healthy longevity and reshape our understanding of the aging process.
A study found that a simple blood test could predict breast cancer risk in older women by measuring biological aging via DNA methylation changes. Lifestyle factors, such as obesity and hormone replacement therapy, also influenced epigenetic aging and breast cancer risk.
A new study published in Aging found that pioglitazone reduced the frequency of skin ulcers in Werner syndrome patients. The research suggests that pioglitazone's anti-inflammatory properties may help wounds heal faster and prevent ulcers from forming.
A meta-analysis found a dose-dependent relationship between alcohol consumption and the risks of cirrhosis and HCC in HBV patients, with daily alcohol consumption exceeding 12g increasing risk by 6.2% and 11.5% respectively.