A study found that plasma pentosidine levels, a marker of advanced glycation end products, were significantly associated with impaired processing speed in schizophrenia patients. The results suggest that reducing AGEs may contribute to improving cognitive function and promoting recovery in patients with schizophrenia.
SourceTokyo Metropolitan Institute of Medical Science·JournalPLOS ONE·TypeData/statistical analysis·DateAug 12, 2021
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers at Baylor College of Medicine developed a machine learning algorithm that analyzes DNA methylation patterns in blood samples to identify individuals with schizophrenia. The study achieved an 80% accuracy rate and identified epigenetic markers that differ between people diagnosed with the condition and those without it.
SourceBaylor College of Medicine·JournalTranslational Psychiatry·TypeExperimental study·DateAug 3, 2021
Researchers have discovered the amygdala's role in pre-attentive mechanisms, shedding light on its connection to schizophrenia and other disorders. The study found that activating brain stem inhibitory neurons via the amygdala is crucial for startle inhibition.
SourceUniversity of Massachusetts Amherst·JournalBMC Biology·TypeExperimental study·DateJul 29, 2021
Scientists have discovered a protein biomarker in blood that could help diagnose schizophrenia at an early age. The study found high levels of active CRMP2 protein, which is uniquely imbalanced in people diagnosed with the condition.
SourceSanford Burnham Prebys·JournalProceedings of the National Academy of Sciences·DateJul 27, 2021
Researchers at the University of Otago have created a new animal model that can accurately simulate psychosis in rats. This breakthrough finding opens up new possibilities for understanding brain mechanisms and developing more effective treatments for schizophrenia.
SourceUniversity of Otago·JournalJournal of Psychopharmacology·DateJul 14, 2021
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers found impaired neurotransmitter release and synaptic signaling in human-derived neurons from patients with schizophrenia and a rare genetic mutation. This discovery provides insight into the cellular pathways perturbed in schizophrenia and offers a lead for studying this biology.
SourceUniversity of Massachusetts Amherst·JournalProceedings of the National Academy of Sciences·DateJul 13, 2021
A study by CU researchers found that choline deficiency in Black pregnant women is linked to increased risk of developmental and behavioral issues in their children's later lives. The research also highlights healthcare disparities in caring for Black mothers and their children in the US.
SourceUniversity of Colorado Anschutz Medical Campus·JournalSchizophrenia Bulletin·DateJul 7, 2021
Researchers have found 22 lipids linked to lower symptom improvement in people with schizophrenia during treatment. The study's findings suggest a complex interplay between metabolic abnormalities and psychiatric health, highlighting the potential of lipidomics as a promising field for new discoveries.
SourceSkolkovo Institute of Science and Technology (Skoltech)·JournalBiomolecules·DateJul 6, 2021
Research found that mice with impaired methylglyoxal detoxification systems exhibited schizophrenia-like behavioral abnormalities, including social interaction and cognitive memory impairments. Low levels of vitamin B6 were also observed in mice and patients with schizophrenia.
SourceTokyo Metropolitan Institute of Medical Science·JournalRedox Biology·DateJul 2, 2021
Neuroscientists at UCL have identified abnormalities in the way memories are 'replayed' in the brains of people with schizophrenia. The study found that individuals with schizophrenia were less able to build a structure of the task, with impaired neural replay linked to their symptoms.
SourceUniversity College London·JournalCell·DateJun 30, 2021
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
Researchers found significant correlations between brain capillary curvature and neurite thickness radius in schizophrenia patients, but not between capillary diameter and neurite thickness. The study suggests neurovascular abnormalities contribute to schizophrenia.
SourceTokyo Metropolitan Institute of Medical Science·JournalScientific Reports·DateJun 13, 2021
A recent study has found a possible link between prostate cancer and schizophrenia, with certain gene polymorphisms correlated to disease prognosis. Polymorphisms in genes controlling neurotransmitter metabolism were studied in patients with prostate cancer, revealing a potential protective effect against schizophrenia-like symptoms.
SourceImpact Journals LLC·JournalOncotarget·DateJun 11, 2021
A study using protein mapping reveals that abnormal glutamate levels in the brains of schizophrenic patients can lead to oxidative stress and apoptosis in neurons, while oligodendrocytes display different responses. This knowledge may contribute to the development of more targeted treatments for schizophrenia.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalEuropean Archives of Psychiatry and Clinical Neuroscience·DateJun 7, 2021
A new study from Columbia University found that young adults with schizophrenia have the highest suicide risk and those aged 65 and older have the lowest. People with schizophrenia overall have a 4.5-fold increased risk of dying from suicide.
SourceColumbia University Irving Medical Center·JournalJAMA Psychiatry·DateMay 26, 2021
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
A study found that Vitamin B6 deficiency is associated with social deficits, cognitive impairment, and hyperactivated noradrenergic systems in mice. Supplementing the brain with Vitamin B6 improved these abnormalities, suggesting a potential therapeutic strategy for schizophrenia patients with Vitamin B6 deficiency.
SourceTokyo Metropolitan Institute of Medical Science·JournalTranslational Psychiatry·DateMay 25, 2021
Researchers discovered that mitochondrial dysfunction is linked to schizophrenia in patients with 22q11.2 deletion syndrome, who are 25 times more likely to develop the condition. Increased mitochondrial biogenesis is associated with the absence of schizophrenia.
SourceChildren's Hospital of Philadelphia·JournalJAMA Psychiatry·DateMay 19, 2021
A new study successfully treated flies displaying behavioral problems linked to schizophrenia-associated genes using common anti-psychotics. The research identified two key genes, Rim and CACNA1A/CACNA1B, which are involved in neurotransmitter release and electrical signaling in neurons.
SourceUniversity of Bristol·JournalTranslational Psychiatry·DateMay 19, 2021
Research finds that medications commonly prescribed for schizophrenia may worsen brain functioning, particularly among patients taking multiple psychotropic drugs. A study of 1,120 participants with schizophrenia found that 63% had an anticholinergic cognitive burden score of at least 3.
SourceUniversity of California - San Diego·JournalAmerican Journal of Psychiatry·DateMay 17, 2021
Sony Alpha a7 IV (Body Only)
Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers used genetic engineering tools to create a virus that can enter specific neurons and insert new genetic code, inducing modified protein production. In mice tests, the alteration was sufficient to modify brain activity, indicating potential biomarker for psychiatric disorders like schizophrenia and autism.
SourceFundação de Amparo à Pesquisa do Estado de São Paulo·DateMay 12, 2021
A new study from Aarhus University finds that almost half of parents with children to a parent with schizophrenia or bipolar disorder also meet the criteria for a mental disorder. This can impact family life and child development. The study suggests increased attention is needed for these families, with specialized efforts recommended.
SourceAarhus University·JournalSchizophrenia Bulletin·DateMay 4, 2021
A study by Penn researchers found that people with schizophrenia have a compromised blood-brain barrier, allowing the immune system to improperly influence the central nervous system. This inflammation contributes to the condition's symptoms. The findings may also apply to other mental disorders.
SourceUniversity of Pennsylvania·JournalBrain·DateApr 20, 2021
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
A simple dietary supplement betaine reduces behavioral symptoms in mice with a genetic mutation that causes schizophrenia. Betaine supplements likely protect proteins that build neurons' cellular skeletons, restoring healthy structures.
SourceUniversity of Tokyo·JournalCell Reports·DateApr 19, 2021
A new study published in Translational Psychiatry reveals that individuals with high genetic predisposition to schizophrenia are disproportionately affected by cannabis use, experiencing a 60% higher risk of psychotic experiences. Cannabis users, compared to non-users, have higher rates of psychotic experiences across the board.
SourceCentre for Addiction and Mental Health·JournalTranslational Psychiatry·DateApr 13, 2021
A multinational study of nearly 200,000 people found significant sex-dependent differences in the genetics of schizophrenia, bipolar disorder, and major depressive disorders. The findings suggest that interactions between genes and sex may affect disease risk and progression.
SourceMassachusetts General Hospital·JournalBiological Psychiatry·DateMar 23, 2021
A pilot study from North Carolina State University and the University of North Carolina at Chapel Hill found evidence of Bartonella infection in the blood of people with schizophrenia and schizoaffective disorder. The study suggests a potential link between Bartonella infection and neuropsychiatric disease, particularly schizophrenia.
SourceNorth Carolina State University·JournalVector-Borne and Zoonotic Diseases·DateMar 23, 2021
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Researchers found that people with schizophrenia, bipolar disorder, or major depression are more likely to die within 30 days and one year after a heart attack. The study highlights chronic health inequalities faced by those with serious mental illness and calls for urgent action to address disparities.
SourceUniversity of Edinburgh·JournalBMC Medicine·DateMar 22, 2021
High-strength nicotine e-cigarettes have been found to be an effective smoking cessation method for adults with schizophrenia. In a 12-week study, 40 participants showed a sustained 50% reduction in smoking or complete abstinence, and significant improvements in blood pressure, heart rate, and quality of life.
SourceOxford University Press USA·JournalNicotine & Tobacco Research·DateMar 16, 2021
Researchers identified somatic gene mutations in brain cells of people with schizophrenia that disrupted synaptic function and affected proteins critical for neural signaling. The study found that these rare mutations could contribute to the disease's neuropathology, particularly in genes associated with glutamate receptor function.
SourceElsevier·JournalBiological Psychiatry·DateMar 9, 2021
Researchers have determined the three-dimensional structure of glycine transporter GlyT1, providing insight into its regulation and potential inhibition. This discovery could lead to effective drugs that inhibit GlyT1 function, with major implications for treating schizophrenia and other mental disorders.
A comprehensive study combining 27 research studies and 10,000 participant data reveals strong associations between cardiovascular risk factors and cognitive impairment in individuals with schizophrenia. The findings suggest that managing cardiovascular conditions is essential to mitigate cognitive decline in these patients.
SourceJAMA Network·JournalJAMA Psychiatry·DateMar 3, 2021
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
A new study by researchers at the University of Texas Health Science Center at Houston found that dropping out of high school, having schizophrenia, or a co-occurring personality disorder increases the likelihood of someone becoming a high utilizer. The research used machine learning to analyze deidentified electronic health record dat...
SourceUniversity of Texas Health Science Center at Houston·JournalJournal of Health Care for the Poor and Underserved·DateFeb 26, 2021
Researchers identified key risk genes associated with schizophrenia and their impact on antipsychotic medication efficacy. Examining these single nucleotide polymorphisms (SNPs) can help differentiate between responsive and treatment-resistant patients.
SourceBentham Science Publishers·JournalCurrent Pharmaceutical Design·DateFeb 25, 2021
Scientists used X-ray technology to compare brain tissues of schizophrenia patients with those of healthy individuals, revealing unique structural differences. The findings suggest a link between these differences and the onset of the disease, paving the way for potential new treatments.
SourceDOE/Argonne National Laboratory·JournalTranslational Psychiatry·DateFeb 23, 2021
Researchers found that neuron structures differ between brain areas and individuals, with variations in shape and curvature affecting cognitive functions. The study used nanotomography to analyze brain tissue samples from 34 schizophrenia and 4 control cases.
SourceTokyo Metropolitan Institute of Medical Science·JournalThe Journal of Positive Psychology·DateFeb 10, 2021
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
A significant link between placental gene-expression loci and neonatal brain volume was found, with stronger correlations in males than females. Early life complications may exacerbate the risk of neurodevelopmental illness in individuals with schizophrenia-associated genetic markers.
SourceProceedings of the National Academy of Sciences·JournalProceedings of the National Academy of Sciences·DateFeb 8, 2021
A genetic scoring study published in PNAS found that specific genes in the placenta can predict a baby's brain size at birth and its rate of cognitive development, which may lead to schizophrenia later in life. The study suggests that targeting placental health may reduce schizophrenia risk, particularly in males.
SourceUniversity of North Carolina Health Care·JournalProceedings of the National Academy of Sciences·DateFeb 8, 2021
Researchers found modest differences in gene expression between individuals with a mental disorder and those without, but more pronounced differences in transcript levels. The study identifies specific transcripts associated with each disorder, providing insights into their distinctness and potential treatment responses.
SourceNIH/National Institute of Mental Health·JournalNeuropsychopharmacology·DateFeb 8, 2021
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
A recent observational study of 7,300 adults with COVID-19 found that individuals with a schizophrenia spectrum diagnosis had an increased risk of death, while mood and anxiety disorders were not associated with higher mortality rates. The study suggests that psychiatric disorders may be linked to poorer outcomes in patients with COVID-19
A new study finds that people with schizophrenia are almost three times more likely to die from COVID-19 than those without the mental disorder. The study, led by researchers at NYU Langone Health, shows that schizophrenia is the biggest risk factor for death after age, with a 2.7-fold increased odds of dying.
SourceNYU Langone Health / NYU Grossman School of Medicine·JournalJAMA Psychiatry·DateJan 27, 2021
Researchers developed a machine learning tool to analyze brain scans and identify risk for earlier diagnosis and treatment. The tool accurately identified individuals with schizotypal personality traits at high risk of developing schizophrenia.
SourceUniversity of Alberta Faculty of Medicine & Dentistry·JournalSchizophrenia·DateJan 26, 2021
A new drug target for schizophrenia will be assessed using a technical approach developed by researchers from the University of Oxford and Earlham Institute. The goal is to identify proteins that may represent promising targets for treatment, which could lead to improved understanding and development of novel treatments.
A study conducted at the University of Turku found that patients with schizophrenia have an increased risk of developing Parkinson's disease. The research suggests that alterations in the brain's dopamine system may be a key factor contributing to this increased risk.
SourceUniversity of Turku·JournalMovement Disorders·DateJan 15, 2021
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
Researchers at UTHealth have discovered a gene signaling pathway linked to schizophrenia using human-induced pluripotent stem cells. The PI3K/GSK3 pathway was found to be dysregulated in neurons from patients with schizophrenia, with SGK1 inhibitor being associated with the condition.
SourceUniversity of Texas Health Science Center at Houston·JournalNeuropsychopharmacology·DateDec 21, 2020
Researchers from the University of Tsukuba found that low-intensity exercise during adolescence can significantly reduce abnormal behaviors in a mouse model of schizophrenia. The study suggests that mild exercise habits during development could have a powerful preventative effect in individuals genetically predisposed to schizophrenia.
SourceUniversity of Tsukuba·JournalBiochemical and Biophysical Research Communications·DateDec 16, 2020
A recent study has identified a genetic variation that influences cognition and IQ in people with schizophrenia, suggesting the possibility of developing new therapies to target learning and memory problems. Higher levels of a specific brain chemical were found to be associated with better visual and working memory.
SourceJohns Hopkins Medicine·JournalAmerican Journal of Psychiatry·DateDec 3, 2020
Researchers found that combining long-acting antipsychotic medication with cognitive training led to significant improvements in cognitive deficits and work/school functioning in schizophrenia patients. The study, published in Psychological Medicine, suggests a potential breakthrough in treating the condition.
SourceUniversity of California - Los Angeles Health Sciences·JournalPsychological Medicine·DateNov 19, 2020
Researchers at Cornell Tech used smartphone data to predict episodes of schizophrenic relapse, analyzing movement, ambient sound and sleep patterns. The method found a median 108% increase in behavior anomalies before relapse.
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
A computer brain circuit has identified a potential mechanism for impaired decision making in schizophrenia, linked to reduced activity of molecules called NDMA receptors. The model's results provide new insight that may inform future treatments for neuropsychiatric conditions.
Researchers found that people with a genetic deletion syndrome are more excitable and experience abnormalities in calcium signaling, leading to an increased risk of developing schizophrenia. The study identified a single gene, DGCR8, as the main player in these cellular defects.
SourceStanford Medicine·JournalNature Medicine·DateSep 28, 2020
The research will develop biomarkers and clinical assessments to improve treatment outcomes for adolescents and young adults at risk of schizophrenia. The five-year study will recruit 1,040 patients with Clinical High Risk (CHR) and healthy controls, using data-driven methods to predict individual clinical trajectories.
SourceUniversity of California - Los Angeles Health Sciences·DateSep 15, 2020
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Digital phenotyping approaches combine smartphone data analysis and machine learning to monitor patients with psychosis spectrum illnesses. Researchers identified promising tools for care improvement, calling for larger studies and expanded efforts in early diagnosis and treatment.
SourceWolters Kluwer Health·JournalHarvard Review of Psychiatry·DateSep 15, 2020
Researchers found that depression is an intrinsic part of early phase psychotic disorders and suggest targeting depression as a key factor in treatment. The study suggests antidepressants alongside anti-psychotic drugs could be an effective additional first-line treatment for psychosis.
SourceUniversity of Birmingham·JournalSchizophrenia Bulletin·DateAug 17, 2020
Researchers at the University of Tokyo have developed a machine learning algorithm that can distinguish between different psychiatric diagnoses, including autism spectrum disorder and schizophrenia. The algorithm uses MRI brain scans to identify variations in brain thickness, surface area, or volume.
SourceUniversity of Tokyo·JournalTranslational Psychiatry·DateAug 17, 2020
Researchers at Kumamoto University found that DNA methylation in the serotonin transporter gene is inversely correlated with amygdala volume in male patients with schizophrenia and bipolar disorder. The study suggests a potential biomarker for onset prediction, diagnosis, and therapeutic effects.
SourceKumamoto University·JournalSchizophrenia Bulletin·DateJul 9, 2020
Kestrel 3000 Pocket Weather Meter
Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.
Researchers at UMBC develop independent vector analysis (IVA) for common subspace extraction (CS) to analyze fMRI data, identifying subgroups of schizophrenia patients with significant clinical significance. The method preserves nuances in data while rendering statistically significant groupings.
SourceUniversity of Maryland Baltimore County·JournalNeuroImage·DateJun 26, 2020
A study of 75,000 patients with schizophrenia spectrum disorders found that those who experienced a mood disorder or hospitalization prior to diagnosis were at the highest risk for suicide. The researchers suggest increasing age limits for first episode psychosis programs and extending clinical follow-up care as potential solutions.
SourceCentre for Addiction and Mental Health·JournalSchizophrenia Research·DateJun 18, 2020
Researchers discovered a link between NMDA receptor dysfunction and sleep spindle deficit in schizophrenia. Medicines targeting these receptors may help treat psychiatric disorders, such as psychosis.
SourceNational Research University Higher School of Economics·JournalSchizophrenia Research·DateJun 5, 2020
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
A new UC San Francisco study found that precise synchronization of high-frequency brain waves is crucial for learning to let go of old rules and make way for new updates. Disrupting these synchronized waves can lead to perseverative behaviors, a common symptom in schizophrenia.
SourceUniversity of California - San Francisco·JournalNature Neuroscience·DateMay 29, 2020
Recent genome-wide association studies identify genetic variants associated with schizophrenia, promising new treatments targeting the underlying biology and pathophysiology of the disorder. Researchers review efforts to bridge the gap between genetic findings and innovative treatments.
SourceWolters Kluwer Health·JournalJournal of Clinical Psychopharmacology·DateMay 21, 2020
Research found that complement gene variants contribute to sex-based differences in vulnerability to autoimmune diseases lupus and Sjögren's syndrome, as well as mental disorder schizophrenia. Complement protein levels vary between men and women, with different age-related elevations and effects on disease incidence.
SourceUniversity of Alabama at Birmingham·JournalNature·DateMay 18, 2020
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.